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Items: 20

1.

Ruxolitinib inhibits cyclosporine-induced proliferation of cutaneous squamous cell carcinoma.

Abikhair Burgo M, Roudiani N, Chen J, Santana AL, Doudican N, Proby C, Felsen D, Carucci JA.

JCI Insight. 2018 Sep 6;3(17). pii: 120750. doi: 10.1172/jci.insight.120750. eCollection 2018 Sep 6.

2.

Inhibition of the CRAF/prohibitin interaction reverses CRAF-dependent resistance to vemurafenib.

Doudican NA, Orlow SJ.

Oncogene. 2017 Jan 19;36(3):423-428. doi: 10.1038/onc.2016.214. Epub 2016 Jun 20.

PMID:
27321184
3.

Personalization of cancer treatment using predictive simulation.

Doudican NA, Kumar A, Singh NK, Nair PR, Lala DA, Basu K, Talawdekar AA, Sultana Z, Tiwari KK, Tyagi A, Abbasi T, Vali S, Vij R, Fiala M, King J, Perle M, Mazumder A.

J Transl Med. 2015 Feb 1;13:43. doi: 10.1186/s12967-015-0399-y.

4.

Predictive simulation approach for designing cancer therapeutic regimens with novel biological mechanisms.

Doudican NA, Mazumder A, Kapoor S, Sultana Z, Kumar A, Talawdekar A, Basu K, Agrawal A, Aggarwal A, Shetty K, Singh NK, Kumar C, Tyagi A, Singh NK, Darlybai JC, Abbasi T, Vali S.

J Cancer. 2014 Apr 25;5(6):406-16. doi: 10.7150/jca.7680. eCollection 2014.

5.

Identification of agents that promote endoplasmic reticulum stress using an assay that monitors luciferase secretion.

Doudican NA, Wen SY, Mazumder A, Orlow SJ.

J Biomol Screen. 2014 Apr;19(4):575-84. doi: 10.1177/1087057113517549. Epub 2013 Dec 26.

6.

Antagonistic effect of small-molecule inhibitors of Wnt/β-catenin in multiple myeloma.

Narayanan BA, Doudican NA, Park J, Xu D, Narayanan NK, Dasgupta R, Mazumder A.

Anticancer Res. 2012 Nov;32(11):4697-707.

7.

XIAP downregulation accompanies mebendazole growth inhibition in melanoma xenografts.

Doudican NA, Byron SA, Pollock PM, Orlow SJ.

Anticancer Drugs. 2013 Feb;24(2):181-8. doi: 10.1097/CAD.0b013e32835a43f1.

PMID:
23059386
8.

Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells via stress-mediated pathways.

Doudican NA, Wen SY, Mazumder A, Orlow SJ.

Oncol Rep. 2012 Nov;28(5):1851-8. doi: 10.3892/or.2012.1977. Epub 2012 Aug 22.

9.

Albendazole sensitizes cancer cells to ionizing radiation.

Patel K, Doudican NA, Schiff PB, Orlow SJ.

Radiat Oncol. 2011 Nov 17;6:160. doi: 10.1186/1748-717X-6-160.

10.

Fluvastatin enhances sorafenib cytotoxicity in melanoma cells via modulation of AKT and JNK signaling pathways.

Zhang S, Doudican NA, Quay E, Orlow SJ.

Anticancer Res. 2011 Oct;31(10):3259-65.

PMID:
21965734
11.

Disulfiram induces copper-dependent stimulation of reactive oxygen species and activation of the extrinsic apoptotic pathway in melanoma.

Morrison BW, Doudican NA, Patel KR, Orlow SJ.

Melanoma Res. 2010 Feb;20(1):11-20. doi: 10.1097/CMR.0b013e328334131d.

PMID:
19966593
12.

Celastrol synergistically enhances temozolomide cytotoxicity in melanoma cells.

Chen M, Rose AE, Doudican N, Osman I, Orlow SJ.

Mol Cancer Res. 2009 Dec;7(12):1946-53. doi: 10.1158/1541-7786.MCR-09-0243. Epub 2009 Nov 24.

13.

Enhancement of arsenic trioxide cytotoxicity by dietary isothiocyanates in human leukemic cells via a reactive oxygen species-dependent mechanism.

Doudican NA, Bowling B, Orlow SJ.

Leuk Res. 2010 Feb;34(2):229-34. doi: 10.1016/j.leukres.2009.05.017. Epub 2009 Jun 21.

14.

Mitochondrial DNA oxidative damage and mutagenesis in Saccharomyces cerevisiae.

Griffiths LM, Doudican NA, Shadel GS, Doetsch PW.

Methods Mol Biol. 2009;554:267-86. doi: 10.1007/978-1-59745-521-3_17.

PMID:
19513680
15.

Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells.

Doudican N, Rodriguez A, Osman I, Orlow SJ.

Mol Cancer Res. 2008 Aug;6(8):1308-15. doi: 10.1158/1541-7786.MCR-07-2159. Epub 2008 Jul 30.

16.

Inhibition of mitochondrial protein translation sensitizes melanoma cells to arsenic trioxide cytotoxicity via a reactive oxygen species dependent mechanism.

Bowling BD, Doudican N, Manga P, Orlow SJ.

Cancer Chemother Pharmacol. 2008 Dec;63(1):37-43. doi: 10.1007/s00280-008-0705-y. Epub 2008 Feb 23.

17.

Oxidative DNA damage causes mitochondrial genomic instability in Saccharomyces cerevisiae.

Doudican NA, Song B, Shadel GS, Doetsch PW.

Mol Cell Biol. 2005 Jun;25(12):5196-204.

18.

Differential involvement of the related DNA helicases Pif1p and Rrm3p in mtDNA point mutagenesis and stability.

O'Rourke TW, Doudican NA, Zhang H, Eaton JS, Doetsch PW, Shadel GS.

Gene. 2005 Jul 18;354:86-92.

PMID:
15907372
19.

Mitochondrial dysfunction due to oxidative mitochondrial DNA damage is reduced through cooperative actions of diverse proteins.

O'Rourke TW, Doudican NA, Mackereth MD, Doetsch PW, Shadel GS.

Mol Cell Biol. 2002 Jun;22(12):4086-93.

20.

Cloning and characterization of murine p53 upstream sequences reveals additional positive transcriptional regulatory elements.

Reisman D, Eaton E, McMillin D, Doudican NA, Boggs K.

Gene. 2001 Aug 22;274(1-2):129-37.

PMID:
11675005

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