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Items: 43

1.

Implications of Image-Defined Risk Factors and Primary-Site Response on Local Control and Radiation Treatment Delivery in the Management of High-Risk Neuroblastoma: Is There a Role for De-escalation of Adjuvant Primary-Site Radiation Therapy?

Lucas JT Jr, McCarville MB, Cooper DA, Doubrovin M, Wakefield D, Santiago T, Li Y, Li X, Krasin M, Santana V, Furman W, Davidoff AM.

Int J Radiat Oncol Biol Phys. 2019 Mar 15;103(4):869-877. doi: 10.1016/j.ijrobp.2018.11.041. Epub 2018 Nov 26.

PMID:
30496881
2.

Managing local-regional failure in children with high-risk neuroblastoma: A single institution experience.

Dove AP, Manole BA, Wakefield DV, Cross SJ, Doubrovin M, Shulkin BL, Merchant TE, Davidoff AM, Furman WL, Krasin MJ, Santana VM, Lucas JT Jr.

Pediatr Blood Cancer. 2018 Dec;65(12):e27408. doi: 10.1002/pbc.27408. Epub 2018 Sep 30.

PMID:
30270551
3.

Evaluation of 11C-Methionine PET and Anatomic MRI Associations in Diffuse Intrinsic Pontine Glioma.

Tinkle CL, Duncan EC, Doubrovin M, Han Y, Li Y, Kim H, Broniscer A, Snyder SE, Merchant TE, Shulkin BL.

J Nucl Med. 2019 Mar;60(3):312-319. doi: 10.2967/jnumed.118.212514. Epub 2018 Aug 2.

4.

Radiomics Features Differentiate Between Normal and Tumoral High-Fdg Uptake.

Hsu CY, Doubrovin M, Hua CH, Mohammed O, Shulkin BL, Kaste S, Federico S, Metzger M, Krasin M, Tinkle C, Merchant TE, Lucas JT Jr.

Sci Rep. 2018 Mar 2;8(1):3913. doi: 10.1038/s41598-018-22319-4.

5.

Developmental Venous Anomalies Mimicking Neoplasm on 11C-Methionine PET and DSC Perfusion MRI.

Harreld JH, Doubrovin M, Butch ER, Edwards A, Shulkin B.

Clin Nucl Med. 2017 May;42(5):e275-e276. doi: 10.1097/RLU.0000000000001637.

6.

Characterization of a c-Rel Inhibitor That Mediates Anticancer Properties in Hematologic Malignancies by Blocking NF-κB-Controlled Oxidative Stress Responses.

Shono Y, Tuckett AZ, Liou HC, Doubrovina E, Derenzini E, Ouk S, Tsai JJ, Smith OM, Levy ER, Kreines FM, Ziegler CG, Scallion MI, Doubrovin M, Heller G, Younes A, O'Reilly RJ, van den Brink MR, Zakrzewski JL.

Cancer Res. 2016 Jan 15;76(2):377-89. doi: 10.1158/0008-5472.CAN-14-2814. Epub 2016 Jan 7.

7.

Monitoring the induction of heat shock factor 1/heat shock protein 70 expression following 17-allylamino-demethoxygeldanamycin treatment by positron emission tomography and optical reporter gene imaging.

Doubrovin M, Che JT, Serganova I, Moroz E, Solit DB, Ageyeva L, Kochetkova T, Pillarsetti N, Finn R, Rosen N, Blasberg RG.

Mol Imaging. 2012 Feb;11(1):67-76.

8.

Successful treatment of EBV-associated posttransplantation lymphoma after cord blood transplantation using third-party EBV-specific cytotoxic T lymphocytes.

Barker JN, Doubrovina E, Sauter C, Jaroscak JJ, Perales MA, Doubrovin M, Prockop SE, Koehne G, O'Reilly RJ.

Blood. 2010 Dec 2;116(23):5045-9. doi: 10.1182/blood-2010-04-281873. Epub 2010 Sep 8.

9.

(124)I-iodopyridopyrimidinone for PET of Abl kinase-expressing tumors in vivo.

Doubrovin M, Kochetkova T, Santos E, Veach DR, Smith-Jones P, Pillarsetty N, Balatoni J, Bornmann W, Gelovani J, Larson SM.

J Nucl Med. 2010 Jan;51(1):121-9. doi: 10.2967/jnumed.109.066126.

10.

Multimodality imaging of TGFbeta signaling in breast cancer metastases.

Serganova I, Moroz E, Vider J, Gogiberidze G, Moroz M, Pillarsetty N, Doubrovin M, Minn A, Thaler HT, Massague J, Gelovani J, Blasberg R.

FASEB J. 2009 Aug;23(8):2662-72. doi: 10.1096/fj.08-126920. Epub 2009 Mar 26.

11.

Imaging transgene activity in vivo.

Gade TP, Koutcher JA, Spees WM, Beattie BJ, Ponomarev V, Doubrovin M, Buchanan IM, Beresten T, Zakian KL, Le HC, Tong WP, Mayer-Kuckuk P, Blasberg RG, Gelovani JG.

Cancer Res. 2008 Apr 15;68(8):2878-84. doi: 10.1158/0008-5472.CAN-07-6028.

12.

In vivo imaging and quantitation of adoptively transferred human antigen-specific T cells transduced to express a human norepinephrine transporter gene.

Doubrovin MM, Doubrovina ES, Zanzonico P, Sadelain M, Larson SM, O'Reilly RJ.

Cancer Res. 2007 Dec 15;67(24):11959-69.

13.

HSP70-inducible hNIS-IRES-eGFP reporter imaging: response to heat shock.

Che J, Doubrovin M, Serganova I, Ageyeva L, Beresten T, Finn R, Blasberg R.

Mol Imaging. 2007 Nov-Dec;6(6):404-16.

PMID:
18053411
14.

Imaging hNET reporter gene expression with 124I-MIBG.

Moroz MA, Serganova I, Zanzonico P, Ageyeva L, Beresten T, Dyomina E, Burnazi E, Finn RD, Doubrovin M, Blasberg RG.

J Nucl Med. 2007 May;48(5):827-36.

15.

A human-derived reporter gene for noninvasive imaging in humans: mitochondrial thymidine kinase type 2.

Ponomarev V, Doubrovin M, Shavrin A, Serganova I, Beresten T, Ageyeva L, Cai C, Balatoni J, Alauddin M, Gelovani J.

J Nucl Med. 2007 May;48(5):819-26. Epub 2007 Apr 27.

16.

Molecular imaging of EGFR kinase activity in tumors with 124I-labeled small molecular tracer and positron emission tomography.

Pal A, Glekas A, Doubrovin M, Balatoni J, Namavari M, Beresten T, Maxwell D, Soghomonyan S, Shavrin A, Ageyeva L, Finn R, Larson SM, Bornmann W, Gelovani JG.

Mol Imaging Biol. 2006 Sep-Oct;8(5):262-77. Erratum in: Mol Imaging Biol. 2006 Nov-Dec;8(6):373. Namavari, Mohammed [added].

PMID:
16897320
17.

Molecular imaging reveals skeletal engraftment sites of transplanted bone marrow cells.

Mayer-Kuckuk P, Doubrovin M, Bidaut L, Budak-Alpdogan T, Cai S, Hubbard V, Alpdogan O, van den Brink M, Bertino JR, Blasberg RG, Banerjee D, Gelovani J.

Cell Transplant. 2006;15(1):75-82.

PMID:
16700332
18.

[131I]FIAU labeling of genetically transduced, tumor-reactive lymphocytes: cell-level dosimetry and dose-dependent toxicity.

Zanzonico P, Koehne G, Gallardo HF, Doubrovin M, Doubrovina E, Finn R, Blasberg RG, Riviere I, O'Reilly RJ, Sadelain M, Larson SM.

Eur J Nucl Med Mol Imaging. 2006 Sep;33(9):988-97. Epub 2006 Apr 11.

PMID:
16607546
19.

Imaging herpes viral thymidine kinase-1 reporter gene expression with a new 18F-labeled probe: 2'-fluoro-2'-deoxy-5-[18F]fluoroethyl-1-beta-d-arabinofuranosyl uracil.

Balatoni JA, Doubrovin M, Ageyeva L, Pillarsetty N, Finn RD, Gelovani JG, Blasberg RG.

Nucl Med Biol. 2005 Nov;32(8):811-9.

PMID:
16253805
20.

hNIS-IRES-eGFP dual reporter gene imaging.

Che J, Doubrovin M, Serganova I, Ageyeva L, Zanzonico P, Blasberg R.

Mol Imaging. 2005 Apr-Jun;4(2):128-36.

PMID:
16105513
21.

SPECT imaging of herpes simplex virus type1 thymidine kinase gene expression by [(123)I]FIAU(1).

Choi SR, Zhuang ZP, Chacko AM, Acton PD, Tjuvajev-Gelovani J, Doubrovin M, Chu DC, Kung HF.

Acad Radiol. 2005 Jul;12(7):798-805.

PMID:
16039533
22.

High-resolution imaging of bone precursor cells within the intact bone marrow cavity of living mice.

Mayer-Kuckuk P, Gade TP, Buchanan IM, Doubrovin M, Ageyeva L, Bertino JR, Boskey AL, Blasberg RG, Koutcher JA, Banerjee D.

Mol Ther. 2005 Jul;12(1):33-41.

23.

Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors.

Minn AJ, Kang Y, Serganova I, Gupta GP, Giri DD, Doubrovin M, Ponomarev V, Gerald WL, Blasberg R, Massagué J.

J Clin Invest. 2005 Jan;115(1):44-55.

24.

Multimodality in vivo molecular-genetic imaging.

Doubrovin M, Serganova I, Mayer-Kuckuk P, Ponomarev V, Blasberg RG.

Bioconjug Chem. 2004 Nov-Dec;15(6):1376-88. Review.

PMID:
15546205
25.
26.

PET-based reporter gene imaging. Assessment of endogenous molecular-genetic events.

Doubrovin M, Ponomarev V, Blasberg RG.

IEEE Eng Med Biol Mag. 2004 Jul-Aug;23(4):38-50. Review. No abstract available.

PMID:
15508384
27.

Positron emission tomography (PET) imaging of tumor-localized Salmonella expressing HSV1-TK.

Soghomonyan SA, Doubrovin M, Pike J, Luo X, Ittensohn M, Runyan JD, Balatoni J, Finn R, Tjuvajev JG, Blasberg R, Bermudes D.

Cancer Gene Ther. 2005 Jan;12(1):101-8.

PMID:
15499377
28.

Molecular imaging of temporal dynamics and spatial heterogeneity of hypoxia-inducible factor-1 signal transduction activity in tumors in living mice.

Serganova I, Doubrovin M, Vider J, Ponomarev V, Soghomonyan S, Beresten T, Ageyeva L, Serganov A, Cai S, Balatoni J, Blasberg R, Gelovani J.

Cancer Res. 2004 Sep 1;64(17):6101-8.

29.

In vivo 5-fluorouracil and fluoronucleotide T1 relaxation time measurements using the variable nutation angle method.

Gade TP, Spees WM, Le HC, Zakian KL, Ponomarev V, Doubrovin M, Gelovani JG, Koutcher JA.

Magn Reson Med. 2004 Jul;52(1):169-73.

30.

A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging.

Ponomarev V, Doubrovin M, Serganova I, Vider J, Shavrin A, Beresten T, Ivanova A, Ageyeva L, Tourkova V, Balatoni J, Bornmann W, Blasberg R, Gelovani Tjuvajev J.

Eur J Nucl Med Mol Imaging. 2004 May;31(5):740-51. Epub 2004 Mar 11.

PMID:
15014901
31.

Evasion from NK cell immunity by MHC class I chain-related molecules expressing colon adenocarcinoma.

Doubrovina ES, Doubrovin MM, Vider E, Sisson RB, O'Reilly RJ, Dupont B, Vyas YM.

J Immunol. 2003 Dec 15;171(12):6891-9.

32.

Development of a new reporter gene system--dsRed/xanthine phosphoribosyltransferase-xanthine for molecular imaging of processes behind the intact blood-brain barrier.

Doubrovin M, Ponomarev V, Serganova I, Soghomonian S, Myagawa T, Beresten T, Ageyeva L, Sadelain M, Koutcher J, Blasberg RG, Tjuvajev JG.

Mol Imaging. 2003 Apr;2(2):93-112.

PMID:
12964307
33.

Imaging expression of cytosine deaminase-herpes virus thymidine kinase fusion gene (CD/TK) expression with [124I]FIAU and PET.

Hackman T, Doubrovin M, Balatoni J, Beresten T, Ponomarev V, Beattie B, Finn R, Bornmann W, Blasberg R, Tjuvajev JG.

Mol Imaging. 2002 Jan-Mar;1(1):36-42.

PMID:
12920859
34.

Cytoplasmically retargeted HSV1-tk/GFP reporter gene mutants for optimization of noninvasive molecular-genetic imaging.

Ponomarev V, Doubrovin M, Serganova I, Beresten T, Vider J, Shavrin A, Ageyeva L, Balatoni J, Blasberg R, Tjuvajev JG.

Neoplasia. 2003 May-Jun;5(3):245-54. doi: 10.1016/S1476-5586(03)80056-8.

35.

Imaging of dihydrofolate reductase fusion gene expression in xenografts of human liver metastases of colorectal cancer in living rats.

Mayer-Kuckuk P, Doubrovin M, Gusani NJ, Gade T, Balatoni J, Akhurst T, Finn R, Fong Y, Koutcher JA, Larson S, Blasberg R, Tjuvajev JG, Bertino JR, Banerjee D.

Eur J Nucl Med Mol Imaging. 2003 Sep;30(9):1281-91. Epub 2003 Mar 27.

PMID:
12664136
36.

Serial in vivo imaging of the targeted migration of human HSV-TK-transduced antigen-specific lymphocytes.

Koehne G, Doubrovin M, Doubrovina E, Zanzonico P, Gallardo HF, Ivanova A, Balatoni J, Teruya-Feldstein J, Heller G, May C, Ponomarev V, Ruan S, Finn R, Blasberg RG, Bornmann W, Riviere I, Sadelain M, O'Reilly RJ, Larson SM, Tjuvajev JG.

Nat Biotechnol. 2003 Apr;21(4):405-13. Epub 2003 Mar 24.

PMID:
12652311
37.

Comparison of radiolabeled nucleoside probes (FIAU, FHBG, and FHPG) for PET imaging of HSV1-tk gene expression.

Tjuvajev JG, Doubrovin M, Akhurst T, Cai S, Balatoni J, Alauddin MM, Finn R, Bornmann W, Thaler H, Conti PS, Blasberg RG.

J Nucl Med. 2002 Aug;43(8):1072-83.

38.

Cells exposed to antifolates show increased cellular levels of proteins fused to dihydrofolate reductase: a method to modulate gene expression.

Mayer-Kuckuk P, Banerjee D, Malhotra S, Doubrovin M, Iwamoto M, Akhurst T, Balatoni J, Bornmann W, Finn R, Larson S, Fong Y, Gelovani Tjuvajev J, Blasberg R, Bertino JR.

Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3400-5. Epub 2002 Mar 12.

39.

Tumor-specific transcriptional targeting of suicide gene therapy.

Qiao J, Doubrovin M, Sauter BV, Huang Y, Guo ZS, Balatoni J, Akhurst T, Blasberg RG, Tjuvajev JG, Chen SH, Woo SL.

Gene Ther. 2002 Feb;9(3):168-75.

40.

Imaging TCR-dependent NFAT-mediated T-cell activation with positron emission tomography in vivo.

Ponomarev V, Doubrovin M, Lyddane C, Beresten T, Balatoni J, Bornman W, Finn R, Akhurst T, Larson S, Blasberg R, Sadelain M, Tjuvajev JG.

Neoplasia. 2001 Nov-Dec;3(6):480-8.

41.

Imaging transcriptional regulation of p53-dependent genes with positron emission tomography in vivo.

Doubrovin M, Ponomarev V, Beresten T, Balatoni J, Bornmann W, Finn R, Humm J, Larson S, Sadelain M, Blasberg R, Gelovani Tjuvajev J.

Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9300-5.

42.

Positron emission tomography imaging for herpes virus infection: Implications for oncolytic viral treatments of cancer.

Bennett JJ, Tjuvajev J, Johnson P, Doubrovin M, Akhurst T, Malholtra S, Hackman T, Balatoni J, Finn R, Larson SM, Federoff H, Blasberg R, Fong Y.

Nat Med. 2001 Jul;7(7):859-63.

PMID:
11433353
43.

Role of chemotherapy in the treatment of low-grade gliomas.

Doubrovin MM, Finlay JL.

Crit Rev Neurosurg. 1998 Sep 14;8(5):310-6.

PMID:
9732546

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