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Items: 21


Humanized Mice for Live-Attenuated Vaccine Research: From Unmet Potential to New Promises.

O'Connell AK, Douam F.

Vaccines (Basel). 2020 Jan 21;8(1). pii: E36. doi: 10.3390/vaccines8010036. Review.


Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses.

Douam F, Ziegler CGK, Hrebikova G, Fant B, Leach R, Parsons L, Wang W, Gaska JM, Winer BY, Heller B, Shalek AK, Ploss A.

Nat Commun. 2018 Nov 28;9(1):5031. doi: 10.1038/s41467-018-07478-2.


Yellow Fever Virus: Knowledge Gaps Impeding the Fight Against an Old Foe.

Douam F, Ploss A.

Trends Microbiol. 2018 Nov;26(11):913-928. doi: 10.1016/j.tim.2018.05.012. Epub 2018 Jun 19. Review.


Species-specific disruption of STING-dependent antiviral cellular defenses by the Zika virus NS2B3 protease.

Ding Q, Gaska JM, Douam F, Wei L, Kim D, Balev M, Heller B, Ploss A.

Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):E6310-E6318. doi: 10.1073/pnas.1803406115. Epub 2018 Jun 18.


The use of humanized mice for studies of viral pathogenesis and immunity.

Douam F, Ploss A.

Curr Opin Virol. 2018 Apr;29:62-71. doi: 10.1016/j.coviro.2018.03.003. Epub 2018 Mar 28. Review.


A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism.

Douam F, Fusil F, Enguehard M, Dib L, Nadalin F, Schwaller L, Hrebikova G, Mancip J, Mailly L, Montserret R, Ding Q, Maisse C, Carlot E, Xu K, Verhoeyen E, Baumert TF, Ploss A, Carbone A, Cosset FL, Lavillette D.

PLoS Pathog. 2018 Mar 5;14(3):e1006908. doi: 10.1371/journal.ppat.1006908. eCollection 2018 Mar.


Type III Interferon-Mediated Signaling Is Critical for Controlling Live Attenuated Yellow Fever Virus Infection In Vivo.

Douam F, Soto Albrecht YE, Hrebikova G, Sadimin E, Davidson C, Kotenko SV, Ploss A.

mBio. 2017 Aug 15;8(4). pii: e00819-17. doi: 10.1128/mBio.00819-17.


Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome.

Douam F, Hrebikova G, Albrecht YE, Sellau J, Sharon Y, Ding Q, Ploss A.

Nat Commun. 2017 Mar 14;8:14781. doi: 10.1038/ncomms14781.


Recent advances in understanding hepatitis C.

Douam F, Ding Q, Ploss A.

F1000Res. 2016 Feb 3;5. pii: F1000 Faculty Rev-131. doi: 10.12688/f1000research.7354.1. eCollection 2016. Review.


Specialization of Hepatitis C Virus Envelope Glycoproteins for B Lymphocytes in Chronically Infected Patients.

Douam F, Bobay LM, Maurin G, Fresquet J, Calland N, Maisse C, Durand T, Cosset FL, Féray C, Lavillette D.

J Virol. 2015 Nov 4;90(2):992-1008. doi: 10.1128/JVI.02516-15. Print 2016 Jan 15.


Genetic Dissection of the Host Tropism of Human-Tropic Pathogens.

Douam F, Gaska JM, Winer BY, Ding Q, von Schaewen M, Ploss A.

Annu Rev Genet. 2015;49:21-45. doi: 10.1146/annurev-genet-112414-054823. Epub 2015 Sep 25. Review.


A Lentiviral Vector Allowing Physiologically Regulated Membrane-anchored and Secreted Antibody Expression Depending on B-cell Maturation Status.

Fusil F, Calattini S, Amirache F, Mancip J, Costa C, Robbins JB, Douam F, Lavillette D, Law M, Defrance T, Verhoeyen E, Cosset FL.

Mol Ther. 2015 Nov;23(11):1734-1747. doi: 10.1038/mt.2015.148. Epub 2015 Aug 18.


New Insights into the Understanding of Hepatitis C Virus Entry and Cell-to-Cell Transmission by Using the Ionophore Monensin A.

Fénéant L, Potel J, François C, Sané F, Douam F, Belouzard S, Calland N, Vausselin T, Rouillé Y, Descamps V, Baumert TF, Duverlie G, Lavillette D, Hober D, Dubuisson J, Wychowski C, Cocquerel L.

J Virol. 2015 Aug;89(16):8346-64. doi: 10.1128/JVI.00192-15. Epub 2015 Jun 3.


Proteomic approaches to analyzing hepatitis C virus biology.

Douam F, Ploss A.

Proteomics. 2015 Jun;15(12):2051-65. doi: 10.1002/pmic.201500009. Epub 2015 May 5. Review.


The mechanism of HCV entry into host cells.

Douam F, Lavillette D, Cosset FL.

Prog Mol Biol Transl Sci. 2015;129:63-107. doi: 10.1016/bs.pmbts.2014.10.003. Epub 2014 Dec 12. Review.


The expression of the hepatocyte SLAMF3 (CD229) receptor enhances the hepatitis C virus infection.

Cartier F, Marcq I, Douam F, Ossart C, Regnier A, Debuysscher V, Lavillette D, Bouhlal H.

PLoS One. 2014 Jun 13;9(6):e99601. doi: 10.1371/journal.pone.0099601. eCollection 2014.


Up-regulation of the ATP-binding cassette transporter A1 inhibits hepatitis C virus infection.

Bocchetta S, Maillard P, Yamamoto M, Gondeau C, Douam F, Lebreton S, Lagaye S, Pol S, Helle F, Plengpanich W, Guérin M, Bourgine M, Michel ML, Lavillette D, Roingeard P, le Goff W, Budkowska A.

PLoS One. 2014 Mar 19;9(3):e92140. doi: 10.1371/journal.pone.0092140. eCollection 2014.


Critical interaction between E1 and E2 glycoproteins determines binding and fusion properties of hepatitis C virus during cell entry.

Douam F, Dao Thi VL, Maurin G, Fresquet J, Mompelat D, Zeisel MB, Baumert TF, Cosset FL, Lavillette D.

Hepatology. 2014 Mar;59(3):776-88. doi: 10.1002/hep.26733. Epub 2014 Jan 28.


Plant science and agricultural productivity: why are we hitting the yield ceiling?

de Bossoreille de Ribou S, Douam F, Hamant O, Frohlich MW, Negrutiu I.

Plant Sci. 2013 Sep;210:159-76. doi: 10.1016/j.plantsci.2013.05.010. Epub 2013 May 23. Review.


The antimalarial ferroquine is an inhibitor of hepatitis C virus.

Vausselin T, Calland N, Belouzard S, Descamps V, Douam F, Helle F, François C, Lavillette D, Duverlie G, Wahid A, Fénéant L, Cocquerel L, Guérardel Y, Wychowski C, Biot C, Dubuisson J.

Hepatology. 2013 Jul;58(1):86-97. doi: 10.1002/hep.26273. Epub 2013 May 14.


Distinct roles in folding, CD81 receptor binding and viral entry for conserved histidine residues of hepatitis C virus glycoprotein E1 and E2.

Boo I, teWierik K, Douam F, Lavillette D, Poumbourios P, Drummer HE.

Biochem J. 2012 Apr 1;443(1):85-94. doi: 10.1042/BJ20110868.


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