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Quercetin protects against atherosclerosis by regulating the expression of PCSK9, CD36, PPARγ, LXRα and ABCA1.

Jia Q, Cao H, Shen D, Li S, Yan L, Chen C, Xing S, Dou F.

Int J Mol Med. 2019 Sep;44(3):893-902. doi: 10.3892/ijmm.2019.4263. Epub 2019 Jul 3.


Anti-atherosclerotic effects of LXRα agonist through induced conversion of M1 macrophage to M2.

Dou F, Chen J, Cao H, Jia Q, Shen D, Liu T, Chen C.

Am J Transl Res. 2019 Jun 15;11(6):3825-3840. eCollection 2019.


Laboratory and Clinical Evaluation of DNA Microarray for the Detection of Carbapenemase Genes in Gram-Negative Bacteria from Hospitalized Patients.

Song Y, Dou F, He S, Zhou Y, Liu Q.

Biomed Res Int. 2019 May 13;2019:8219748. doi: 10.1155/2019/8219748. eCollection 2019.


Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity.

Kazak L, Rahbani JF, Samborska B, Lu GZ, Jedrychowski MP, Lajoie M, Zhang S, Ramsay LC, Dou FY, Tenen D, Chouchani ET, Dzeja P, Watson IR, Tsai L, Rosen ED, Spiegelman BM.

Nat Metab. 2019;1(3):360-370. doi: 10.1038/s42255-019-0035-x. Epub 2019 Feb 25. No abstract available.


Effect of Quercetin on Atherosclerosis Based on Expressions of ABCA1, LXR-α and PCSK9 in ApoE-/- Mice.

Li SS, Cao H, Shen DZ, Chen C, Xing SL, Dou FF, Jia QL.

Chin J Integr Med. 2019 May 30. doi: 10.1007/s11655-019-2942-9. [Epub ahead of print]


Study on the multi-targets mechanism of triphala on cardio-cerebral vascular diseases based on network pharmacology.

Wang W, Liu T, Yang L, Ma Y, Dou F, Shi L, Wen A, Ding Y.

Biomed Pharmacother. 2019 Aug;116:108994. doi: 10.1016/j.biopha.2019.108994. Epub 2019 May 18.


An Evolutionarily Conserved uORF Regulates PGC1α and Oxidative Metabolism in Mice, Flies, and Bluefin Tuna.

Dumesic PA, Egan DF, Gut P, Tran MT, Parisi A, Chatterjee N, Jedrychowski M, Paschini M, Kazak L, Wilensky SE, Dou F, Bogoslavski D, Cartier JA, Perrimon N, Kajimura S, Parikh SM, Spiegelman BM.

Cell Metab. 2019 Jul 2;30(1):190-200.e6. doi: 10.1016/j.cmet.2019.04.013. Epub 2019 May 16.


Biobased Sanitizer Delivery System for Improved Sanitation of Bacterial and Fungal Biofilms.

Huang K, Dou F, Nitin N.

ACS Appl Mater Interfaces. 2019 May 15;11(19):17204-17214. doi: 10.1021/acsami.9b02428. Epub 2019 Apr 30.


Synthesis and evaluation of histamine H3 receptor ligand based on lactam scaffold as agents for treating neuropathic pain.

Dou F, Cao X, Jing P, Wu C, Zhang Y, Chen Y, Zhang G.

Bioorg Med Chem Lett. 2019 Jun 15;29(12):1492-1496. doi: 10.1016/j.bmcl.2019.04.015. Epub 2019 Apr 8.


Microbial Transformation of Flavonoids by Isaria fumosorosea ACCC 37814.

Dou F, Wang Z, Li G, Dun B.

Molecules. 2019 Mar 15;24(6). pii: E1028. doi: 10.3390/molecules24061028.


Proteomic Analysis of Hydroxysafflor Yellow A Against Cerebral Ischemia/Reperfusion Injury in Rats.

Xu H, Liu T, Wang W, Su N, Yang L, Yang Z, Dou F, Cui J, Fei F, Ma J, Wen A, Ding Y.

Rejuvenation Res. 2019 Mar 19. doi: 10.1089/rej.2018.2145. [Epub ahead of print]


EriB targeted inhibition of microglia activity attenuates MPP+ induced DA neuron injury through the NF-κB signaling pathway.

Dou F, Chu X, Zhang B, Liang L, Lu G, Ding J, Chen S.

Mol Brain. 2018 Dec 18;11(1):75. doi: 10.1186/s13041-018-0418-z.


Synthesis and Biological Evaluation of Sigma-1 (σ1 ) Receptor Ligands Based on Phenyl-1,2,4-oxadiazole Derivatives.

Cao X, Yao Z, Dou F, Zhang Y, Qiu Y, Zhao S, Xu X, Liu X, Liu BF, Chen Y, Zhang G.

Chem Biodivers. 2019 Mar;16(3):e1800599. doi: 10.1002/cbdv.201800599. Epub 2019 Feb 18.


Disrupted-in-schizophrenia-1 protects synaptic plasticity in a transgenic mouse model of Alzheimer's disease as a mitophagy receptor.

Wang ZT, Lu MH, Zhang Y, Ji WL, Lei L, Wang W, Fang LP, Wang LW, Yu F, Wang J, Li ZY, Wang JR, Wang TH, Dou F, Wang QW, Wang XL, Li S, Ma QH, Xu RX.

Aging Cell. 2019 Feb;18(1):e12860. doi: 10.1111/acel.12860. Epub 2018 Nov 28.


Ca2+-dependent endoplasmic reticulum stress correlation with astrogliosis involves upregulation of KCa3.1 and inhibition of AKT/mTOR signaling.

Yu Z, Dou F, Wang Y, Hou L, Chen H.

J Neuroinflammation. 2018 Nov 15;15(1):316. doi: 10.1186/s12974-018-1351-x.


Microarray-Based Detection and Clinical Evaluation for Helicobacter pylori Resistance to Clarithromycin or Levofloxacin and the Genotype of CYP2C19 in 1083 Patients.

Song Y, Dou F, Zhou Z, Yang N, Zhong J, Pan J, Liu Q, Zhang J, Wang S.

Biomed Res Int. 2018 Sep 10;2018:2684836. doi: 10.1155/2018/2684836. eCollection 2018.


Brain Aging: Hsp90 and Neurodegenerative Diseases.

Wang K, Shang Y, Dou F.

Adv Exp Med Biol. 2018;1086:93-103. doi: 10.1007/978-981-13-1117-8_6. Review.


Aloe-Emodin Ameliorates Renal Fibrosis Via Inhibiting PI3K/Akt/mTOR Signaling Pathway In Vivo and In Vitro.

Dou F, Liu Y, Liu L, Wang J, Sun T, Mu F, Guo Q, Guo C, Jia N, Liu W, Ding Y, Wen A.

Rejuvenation Res. 2019 Jun;22(3):218-229. doi: 10.1089/rej.2018.2104. Epub 2018 Oct 24.


Overexpressed TTC3 Protein Tends to be Cleaved into Fragments and Form Aggregates in the Nucleus.

Gong Y, Wang K, Xiao SP, Mi P, Li W, Shang Y, Dou F.

Neuromolecular Med. 2019 Mar;21(1):85-96. doi: 10.1007/s12017-018-8509-7. Epub 2018 Sep 10.


Modulation of the gamma-secretase activity as a therapy against human hepatocellular carcinoma.

Shen Y, Yin Y, Peng Y, Lv D, Miao F, Dou F, Zhang J.

J Cancer Res Ther. 2018 Jun;14(Supplement):S473-S479. doi: 10.4103/0973-1482.174542.


Ablation of PM20D1 reveals N-acyl amino acid control of metabolism and nociception.

Long JZ, Roche AM, Berdan CA, Louie SM, Roberts AJ, Svensson KJ, Dou FY, Bateman LA, Mina AI, Deng Z, Jedrychowski MP, Lin H, Kamenecka TM, Asara JM, Griffin PR, Banks AS, Nomura DK, Spiegelman BM.

Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6937-E6945. doi: 10.1073/pnas.1803389115. Epub 2018 Jul 2.


Ultra Performance Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry-Based Metabonomics Reveal Protective Effect of Terminalia chebula Extract on Ischemic Stroke Rats.

Liu W, Mu F, Liu T, Xu H, Chen J, Jia N, Zhang Y, Dou F, Shi L, Li Y, Wen A, Ding Y.

Rejuvenation Res. 2018 Dec;21(6):541-552. doi: 10.1089/rej.2018.2082. Epub 2018 Jul 17.


Genome-wide identification of genes involved in polyamine biosynthesis and the role of exogenous polyamines in Malus hupehensis Rehd. under alkaline stress.

Gong X, Dou F, Cheng X, Zhou J, Zou Y, Ma F.

Gene. 2018 Aug 30;669:52-62. doi: 10.1016/j.gene.2018.05.077. Epub 2018 May 22.


Association between oncogenic status and risk of venous thromboembolism in patients with non-small cell lung cancer.

Dou F, Li H, Zhu M, Liang L, Zhang Y, Yi J, Zhang Y.

Respir Res. 2018 May 9;19(1):88. doi: 10.1186/s12931-018-0791-2.


Discovery of Hydrolysis-Resistant Isoindoline N-Acyl Amino Acid Analogues that Stimulate Mitochondrial Respiration.

Lin H, Long JZ, Roche AM, Svensson KJ, Dou FY, Chang MR, Strutzenberg T, Ruiz C, Cameron MD, Novick SJ, Berdan CA, Louie SM, Nomura DK, Spiegelman BM, Griffin PR, Kamenecka TM.

J Med Chem. 2018 Apr 12;61(7):3224-3230. doi: 10.1021/acs.jmedchem.8b00029. Epub 2018 Mar 22.


An Integrated Lipidomics and Phenotype Study Reveals Protective Effect and Biochemical Mechanism of Traditionally Used Alisma orientale Juzepzuk in Chronic Kidney Disease.

Dou F, Miao H, Wang JW, Chen L, Wang M, Chen H, Wen AD, Zhao YY.

Front Pharmacol. 2018 Feb 8;9:53. doi: 10.3389/fphar.2018.00053. eCollection 2018.


Synergistic neuroprotective effects of Danshensu and hydroxysafflor yellow A on cerebral ischemia-reperfusion injury in rats.

Xu H, Liu W, Liu T, Su N, Guo C, Feng X, Dou F, Ding Y, Shi L, Wen A.

Oncotarget. 2017 Dec 15;8(70):115434-115443. doi: 10.18632/oncotarget.23272. eCollection 2017 Dec 29.


Tetratricopeptide repeat domain 3 overexpression tends to form aggregates and inhibit ubiquitination and degradation of DNA polymerase γ.

Gong Y, Wang X, Shang X, Xiao SP, Li W, Shang Y, Dou F.

Oncotarget. 2017 Nov 17;8(63):106475-106485. doi: 10.18632/oncotarget.22476. eCollection 2017 Dec 5.


Salidroside slows the progression of EA.hy926 cell senescence by regulating the cell cycle in an atherosclerosis model.

Sun L, Dou F, Chen J, Chi H, Xing S, Liu T, Sun S, Chen C.

Mol Med Rep. 2018 Jan;17(1):257-263. doi: 10.3892/mmr.2017.7872. Epub 2017 Oct 25.


PD-L1 and PD-1 expression are correlated with distinctive clinicopathological features in papillary thyroid carcinoma.

Bai Y, Niu D, Huang X, Jia L, Kang Q, Dou F, Ji X, Xue W, Liu Y, Li Z, Feng Q, Lin D, Kakudo K.

Diagn Pathol. 2017 Oct 3;12(1):72. doi: 10.1186/s13000-017-0662-z.


Ramsey interferometry of a bosonic Josephson junction in an optical cavity.

Li SC, Dou FQ, Fu LB.

Opt Lett. 2017 Oct 1;42(19):3952-3955. doi: 10.1364/OL.42.003952.


Exogenous Melatonin Alleviates Alkaline Stress in Malus hupehensis Rehd. by Regulating the Biosynthesis of Polyamines.

Gong X, Shi S, Dou F, Song Y, Ma F.

Molecules. 2017 Sep 13;22(9). pii: E1542. doi: 10.3390/molecules22091542.


Telmisartan improves vascular remodeling through ameliorating prooxidant and profibrotic mechanisms in hypertension via the involvement of transforming growth factor-β1.

Shang P, Liu T, Liu W, Li Y, Dou F, Zhang Y, Sun L, Zhang T, Zhu Z, Mu F, Ding Y, Wen A.

Mol Med Rep. 2017 Oct;16(4):4537-4544. doi: 10.3892/mmr.2017.7177. Epub 2017 Aug 4.


Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.

Chen L, Chen DQ, Wang M, Liu D, Chen H, Dou F, Vaziri ND, Zhao YY.

Chem Biol Interact. 2017 Aug 1;273:56-72. doi: 10.1016/j.cbi.2017.05.025. Epub 2017 Jun 2.


Biomarkers of oxidative damage in bacteria for the assessment of sanitation efficacy in lettuce wash water.

Cossu A, Dou F, Young GM, Nitin N.

Appl Microbiol Biotechnol. 2017 Jul;101(13):5365-5375. doi: 10.1007/s00253-017-8314-5. Epub 2017 May 16.


Use of a combination of CEA and tumor budding to identify high-risk patients with stage II colon cancer.

Du C, Xue W, Dou F, Peng Y, Yao Y, Zhao J, Gu J.

Int J Biol Markers. 2017 Jul 24;32(3):e267-e273. doi: 10.5301/jbm.5000255.


Mussel-Inspired Thermoresponsive Polypeptide-Pluronic Copolymers for Versatile Surgical Adhesives and Hemostasis.

Lu D, Wang H, Li T, Li Y, Dou F, Sun S, Guo H, Liao S, Yang Z, Wei Q, Lei Z.

ACS Appl Mater Interfaces. 2017 May 24;9(20):16756-16766. doi: 10.1021/acsami.6b16575. Epub 2017 May 15.


[Clinicopathologic characteristics of thyroid-like follicular carcinoma of the kidney: an analysis of five cases and review of literature].

Chen X, Dou FX, Cheng XB, Guo AT, Shi HY.

Zhonghua Bing Li Xue Za Zhi. 2016 Oct 8;45(10):687-691. doi: 10.3760/cma.j.issn.0529-5807.2016.10.004. Review. Chinese.


Activation of the KCa3.1 channel contributes to traumatic scratch injury-induced reactive astrogliosis through the JNK/c-Jun signaling pathway.

Yi M, Dou F, Lu Q, Yu Z, Chen H.

Neurosci Lett. 2016 Jun 15;624:62-71. doi: 10.1016/j.neulet.2016.05.004. Epub 2016 May 6.


Soil Texture and Cultivar Effects on Rice (Oryza sativa, L.) Grain Yield, Yield Components and Water Productivity in Three Water Regimes.

Dou F, Soriano J, Tabien RE, Chen K.

PLoS One. 2016 Mar 15;11(3):e0150549. doi: 10.1371/journal.pone.0150549. eCollection 2016.


[Children acute sinusitis conservative treatment of orbital cellulitis].

Sun X, Dou F, Li W.

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Nov;29(21):1908-10. Chinese. No abstract available.


Cycloheximide Treatment Causes a ZVAD-Sensitive Protease-Dependent Cleavage of Human Tau in Drosophila Cells.

Geng J, Xia L, Li W, Zhao C, Dou F.

J Alzheimers Dis. 2016;49(4):1161-8. doi: 10.3233/JAD-150423.


Selective Modulation of Axonal Sodium Channel Subtypes by 5-HT1A Receptor in Cortical Pyramidal Neuron.

Yin L, Rasch MJ, He Q, Wu S, Dou F, Shu Y.

Cereb Cortex. 2017 Jan 1;27(1):509-521. doi: 10.1093/cercor/bhv245.


Application of intra-molecular fluorescence complementation in the topology examination of polytopic proteins in living cells.

Chang X, Cao G, Wang K, Zhang X, Dou F.

Acta Biochim Biophys Sin (Shanghai). 2015 Aug;47(8):654-6. doi: 10.1093/abbs/gmv048. Epub 2015 Jun 9. No abstract available.


Simulation of biomass yield and soil organic carbon under bioenergy sorghum production.

Dou F, Wight JP, Wilson LT, Storlien JO, Hons FM.

PLoS One. 2014 Dec 22;9(12):e115598. doi: 10.1371/journal.pone.0115598. eCollection 2014.


Fuzzy temporal logic based railway passenger flow forecast model.

Dou F, Jia L, Wang L, Xu J, Huang Y.

Comput Intell Neurosci. 2014;2014:950371. doi: 10.1155/2014/950371. Epub 2014 Nov 5.


Construction of human Fab library and screening of a single-domain antibody of amyloid-beta 42 oligomers.

Yuan Z, Du M, Chen Y, Dou F.

Neural Regen Res. 2013 Nov 25;8(33):3107-15. doi: 10.3969/j.issn.1673-5374.2013.33.004.


Optimal path choice in railway passenger travel network based on residual train capacity.

Dou F, Yan K, Huang Y, Wang L, Jia L.

ScientificWorldJournal. 2014;2014:153949. doi: 10.1155/2014/153949. Epub 2014 Jul 6.


[An outbreak of beta-hemolytic streptococcal caused tonsillitis in a hospital of Chengdu city].

Zhang S, Feng M, Zeng W, Tuo X, He Y, An H, He Y, Chen W, Liu Z, Feng G, Chen J, Dou F.

Zhonghua Liu Xing Bing Xue Za Zhi. 2014 Mar;35(3):295-8. Chinese.


The C-terminus of tau protein plays an important role in its stability and toxicity.

Geng J, Xia L, Li W, Dou F.

J Mol Neurosci. 2015 Jan;55(1):251-259. doi: 10.1007/s12031-014-0314-7. Epub 2014 May 2.


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