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Items: 1 to 50 of 69

1.

Effects of Alterations to the CX3C Motif and Secreted Form of Human Respiratory Syncytial Virus (RSV) G Protein on Immune Responses to a Parainfluenza Virus Vector Expressing the RSV G Protein.

Liang B, Kabatova B, Kabat J, Dorward DW, Liu X, Surman S, Liu X, Moseman AP, Buchholz UJ, Collins PL, Munir S.

J Virol. 2019 Mar 21;93(7). pii: e02043-18. doi: 10.1128/JVI.02043-18. Print 2019 Apr 1.

PMID:
30651356
2.

Regulatory T cells mediate specific suppression by depleting peptide-MHC class II from dendritic cells.

Akkaya B, Oya Y, Akkaya M, Al Souz J, Holstein AH, Kamenyeva O, Kabat J, Matsumura R, Dorward DW, Glass DD, Shevach EM.

Nat Immunol. 2019 Feb;20(2):218-231. doi: 10.1038/s41590-018-0280-2. Epub 2019 Jan 14.

3.

Increased Mitochondrial Biogenesis and Reactive Oxygen Species Production Accompany Prolonged CD4+ T Cell Activation.

Akkaya B, Roesler AS, Miozzo P, Theall BP, Al Souz J, Smelkinson MG, Kabat J, Traba J, Sack MN, Brzostowski JA, Pena M, Dorward DW, Pierce SK, Akkaya M.

J Immunol. 2018 Dec 1;201(11):3294-3306. doi: 10.4049/jimmunol.1800753. Epub 2018 Oct 29.

PMID:
30373851
4.

A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation.

Breglio KF, Amato R, Eastman R, Lim P, Sa JM, Guha R, Ganesan S, Dorward DW, Klumpp-Thomas C, McKnight C, Fairhurst RM, Roberts D, Thomas C, Simon AK.

Malar J. 2018 Oct 26;17(1):391. doi: 10.1186/s12936-018-2532-x.

5.

Cutting Edge: Quantitative Determination of CD40L Threshold for IL-12 and IL-23 Production from Dendritic Cells.

Abdi K, Laky K, Padhan K, Petrovas C, Skinner J, Kabat J, Dorward DW, Brzostowski J, Long EO, Trinchieri G, Varma R.

J Immunol. 2018 Nov 15;201(10):2879-2884. doi: 10.4049/jimmunol.1800721. Epub 2018 Oct 12.

6.

Second signals rescue B cells from activation-induced mitochondrial dysfunction and death.

Akkaya M, Traba J, Roesler AS, Miozzo P, Akkaya B, Theall BP, Sohn H, Pena M, Smelkinson M, Kabat J, Dahlstrom E, Dorward DW, Skinner J, Sack MN, Pierce SK.

Nat Immunol. 2018 Aug;19(8):871-884. doi: 10.1038/s41590-018-0156-5. Epub 2018 Jul 9.

7.

Toll-like receptor 9 antagonizes antibody affinity maturation.

Akkaya M, Akkaya B, Kim AS, Miozzo P, Sohn H, Pena M, Roesler AS, Theall BP, Henke T, Kabat J, Lu J, Dorward DW, Dahlstrom E, Skinner J, Miller LH, Pierce SK.

Nat Immunol. 2018 Mar;19(3):255-266. doi: 10.1038/s41590-018-0052-z. Epub 2018 Feb 23.

8.

Early Intracellular Trafficking of Granulibacter bethesdensis in Human Macrophages.

Chu J, Smelkinson MG, Dorward DW, Zarember KA, Gallin JI.

Infect Immun. 2017 May 23;85(6). pii: e00847-16. doi: 10.1128/IAI.00847-16. Print 2017 Jun.

9.

Cellular prion protein is present in mitochondria of healthy mice.

Faris R, Moore RA, Ward A, Race B, Dorward DW, Hollister JR, Fischer ER, Priola SA.

Sci Rep. 2017 Feb 2;7:41556. doi: 10.1038/srep41556.

10.

Survival of Carbapenem-Resistant Klebsiella pneumoniae Sequence Type 258 in Human Blood.

DeLeo FR, Kobayashi SD, Porter AR, Freedman B, Dorward DW, Chen L, Kreiswirth BN.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02533-16. doi: 10.1128/AAC.02533-16. Print 2017 Apr.

11.

Cytoarchitecture of Zika virus infection in human neuroblastoma and Aedes albopictus cell lines.

Offerdahl DK, Dorward DW, Hansen BT, Bloom ME.

Virology. 2017 Jan 15;501:54-62. doi: 10.1016/j.virol.2016.11.002. Epub 2016 Nov 16.

12.

Packaging and Prefusion Stabilization Separately and Additively Increase the Quantity and Quality of Respiratory Syncytial Virus (RSV)-Neutralizing Antibodies Induced by an RSV Fusion Protein Expressed by a Parainfluenza Virus Vector.

Liang B, Ngwuta JO, Herbert R, Swerczek J, Dorward DW, Amaro-Carambot E, Mackow N, Kabatova B, Lingemann M, Surman S, Yang L, Chen M, Moin SM, Kumar A, McLellan JS, Kwong PD, Graham BS, Schaap-Nutt A, Collins PL, Munir S.

J Virol. 2016 Oct 14;90(21):10022-10038. doi: 10.1128/JVI.01196-16. Print 2016 Nov 1.

13.

Zinc-Induced Polymerization of Killer-Cell Ig-like Receptor into Filaments Promotes Its Inhibitory Function at Cytotoxic Immunological Synapses.

Kumar S, Rajagopalan S, Sarkar P, Dorward DW, Peterson ME, Liao HS, Guillermier C, Steinhauser ML, Vogel SS, Long EO.

Mol Cell. 2016 Apr 7;62(1):21-33. doi: 10.1016/j.molcel.2016.03.009.

14.

Phagocytosis and Killing of Carbapenem-Resistant ST258 Klebsiella pneumoniae by Human Neutrophils.

Kobayashi SD, Porter AR, Dorward DW, Brinkworth AJ, Chen L, Kreiswirth BN, DeLeo FR.

J Infect Dis. 2016 May 15;213(10):1615-22. doi: 10.1093/infdis/jiw001. Epub 2016 Jan 14.

15.

Prion Protein Prolines 102 and 105 and the Surrounding Lysine Cluster Impede Amyloid Formation.

Kraus A, Anson KJ, Raymond LD, Martens C, Groveman BR, Dorward DW, Caughey B.

J Biol Chem. 2015 Aug 28;290(35):21510-22. doi: 10.1074/jbc.M115.665844. Epub 2015 Jul 14.

16.

Efficient uptake and dissemination of scrapie prion protein by astrocytes and fibroblasts from adult hamster brain.

Hollister JR, Lee KS, Dorward DW, Baron GS.

PLoS One. 2015 Jan 30;10(1):e0115351. doi: 10.1371/journal.pone.0115351. eCollection 2015.

17.

Validation of normal human bronchial epithelial cells as a model for influenza A infections in human distal trachea.

Davis AS, Chertow DS, Moyer JE, Suzich J, Sandouk A, Dorward DW, Logun C, Shelhamer JH, Taubenberger JK.

J Histochem Cytochem. 2015 May;63(5):312-28. doi: 10.1369/0022155415570968. Epub 2015 Jan 20.

18.

Charge neutralization of the central lysine cluster in prion protein (PrP) promotes PrP(Sc)-like folding of recombinant PrP amyloids.

Groveman BR, Kraus A, Raymond LD, Dolan MA, Anson KJ, Dorward DW, Caughey B.

J Biol Chem. 2015 Jan 9;290(2):1119-28. doi: 10.1074/jbc.M114.619627. Epub 2014 Nov 21.

19.

Glycosylphosphatidylinositol anchoring directs the assembly of Sup35NM protein into non-fibrillar, membrane-bound aggregates.

Marshall KE, Offerdahl DK, Speare JO, Dorward DW, Hasenkrug A, Carmody AB, Baron GS.

J Biol Chem. 2014 May 2;289(18):12245-63. doi: 10.1074/jbc.M114.556639. Epub 2014 Mar 13.

20.

Staphylococcus aureus leukotoxin GH promotes formation of neutrophil extracellular traps.

Malachowa N, Kobayashi SD, Freedman B, Dorward DW, DeLeo FR.

J Immunol. 2013 Dec 15;191(12):6022-9. doi: 10.4049/jimmunol.1301821. Epub 2013 Nov 4.

21.

Yersinia pestis subverts the dermal neutrophil response in a mouse model of bubonic plague.

Shannon JG, Hasenkrug AM, Dorward DW, Nair V, Carmody AB, Hinnebusch BJ.

MBio. 2013 Aug 27;4(5):e00170-13. doi: 10.1128/mBio.00170-13.

22.

Role for chlamydial inclusion membrane proteins in inclusion membrane structure and biogenesis.

Mital J, Miller NJ, Dorward DW, Dooley CA, Hackstadt T.

PLoS One. 2013 May 17;8(5):e63426. doi: 10.1371/journal.pone.0063426. Print 2013.

23.

Characterization of the Bhanja serogroup viruses (Bunyaviridae): a novel species of the genus Phlebovirus and its relationship with other emerging tick-borne phleboviruses.

Matsuno K, Weisend C, Travassos da Rosa AP, Anzick SL, Dahlstrom E, Porcella SF, Dorward DW, Yu XJ, Tesh RB, Ebihara H.

J Virol. 2013 Apr;87(7):3719-28. doi: 10.1128/JVI.02845-12. Epub 2013 Jan 16.

24.

Characterization of the Bat proteins in the oxidative stress response of Leptospira biflexa.

Stewart PE, Carroll JA, Dorward DW, Stone HH, Sarkar A, Picardeau M, Rosa PA.

BMC Microbiol. 2012 Dec 13;12:290. doi: 10.1186/1471-2180-12-290.

25.

A three-dimensional comparison of tick-borne flavivirus infection in mammalian and tick cell lines.

Offerdahl DK, Dorward DW, Hansen BT, Bloom ME.

PLoS One. 2012;7(10):e47912. doi: 10.1371/journal.pone.0047912. Epub 2012 Oct 24.

26.

Isolation of novel synthetic prion strains by amplification in transgenic mice coexpressing wild-type and anchorless prion proteins.

Raymond GJ, Race B, Hollister JR, Offerdahl DK, Moore RA, Kodali R, Raymond LD, Hughson AG, Rosenke R, Long D, Dorward DW, Baron GS.

J Virol. 2012 Nov;86(21):11763-78. doi: 10.1128/JVI.01353-12. Epub 2012 Aug 22.

27.

Scanning electron microscopy.

Fischer ER, Hansen BT, Nair V, Hoyt FH, Dorward DW.

Curr Protoc Microbiol. 2012 May;Chapter 2:Unit 2B.2.. doi: 10.1002/9780471729259.mc02b02s25.

28.

Effect of glycans and the glycophosphatidylinositol anchor on strain dependent conformations of scrapie prion protein: improved purifications and infrared spectra.

Baron GS, Hughson AG, Raymond GJ, Offerdahl DK, Barton KA, Raymond LD, Dorward DW, Caughey B.

Biochemistry. 2011 May 31;50(21):4479-90. doi: 10.1021/bi2003907. Epub 2011 May 3.

29.

Rapid neutrophil destruction following phagocytosis of Staphylococcus aureus.

Kobayashi SD, Braughton KR, Palazzolo-Ballance AM, Kennedy AD, Sampaio E, Kristosturyan E, Whitney AR, Sturdevant DE, Dorward DW, Holland SM, Kreiswirth BN, Musser JM, DeLeo FR.

J Innate Immun. 2010;2(6):560-75. doi: 10.1159/000317134. Epub 2010 Jun 26.

30.

Coxiella burnetii phase I and II variants replicate with similar kinetics in degradative phagolysosome-like compartments of human macrophages.

Howe D, Shannon JG, Winfree S, Dorward DW, Heinzen RA.

Infect Immun. 2010 Aug;78(8):3465-74. doi: 10.1128/IAI.00406-10. Epub 2010 Jun 1.

31.

Biological characterization of Chlamydia trachomatis plasticity zone MACPF domain family protein CT153.

Taylor LD, Nelson DE, Dorward DW, Whitmire WM, Caldwell HD.

Infect Immun. 2010 Jun;78(6):2691-9. doi: 10.1128/IAI.01455-09. Epub 2010 Mar 29.

32.

Acid phosphatases do not contribute to the pathogenesis of type A Francisella tularensis.

Child R, Wehrly TD, Rockx-Brouwer D, Dorward DW, Celli J.

Infect Immun. 2010 Jan;78(1):59-67. doi: 10.1128/IAI.00965-09. Epub 2009 Oct 26.

33.

The heart is an early target of anthrax lethal toxin in mice: a protective role for neuronal nitric oxide synthase (nNOS).

Moayeri M, Crown D, Dorward DW, Gardner D, Ward JM, Li Y, Cui X, Eichacker P, Leppla SH.

PLoS Pathog. 2009 May;5(5):e1000456. doi: 10.1371/journal.ppat.1000456. Epub 2009 May 29.

34.

Chimeric human parainfluenza virus bearing the Ebola virus glycoprotein as the sole surface protein is immunogenic and highly protective against Ebola virus challenge.

Bukreyev A, Marzi A, Feldmann F, Zhang L, Yang L, Ward JM, Dorward DW, Pickles RJ, Murphy BR, Feldmann H, Collins PL.

Virology. 2009 Jan 20;383(2):348-61. doi: 10.1016/j.virol.2008.09.030. Epub 2008 Nov 17.

35.

Specific biarsenical labeling of cell surface proteins allows fluorescent- and biotin-tagging of amyloid precursor protein and prion proteins.

Taguchi Y, Shi ZD, Ruddy B, Dorward DW, Greene L, Baron GS.

Mol Biol Cell. 2009 Jan;20(1):233-44. doi: 10.1091/mbc.E08-06-0635. Epub 2008 Nov 5.

36.

Induction of TRAIL- and TNF-alpha-dependent apoptosis in human monocyte-derived dendritic cells by microfilariae of Brugia malayi.

Semnani RT, Venugopal PG, Mahapatra L, Skinner JA, Meylan F, Chien D, Dorward DW, Chaussabel D, Siegel RM, Nutman TB.

J Immunol. 2008 Nov 15;181(10):7081-9.

37.

Development and validation of a model for predicting emergency admissions over the next year (PEONY): a UK historical cohort study.

Donnan PT, Dorward DW, Mutch B, Morris AD.

Arch Intern Med. 2008 Jul 14;168(13):1416-22. doi: 10.1001/archinte.168.13.1416.

PMID:
18625922
38.

The avian malaria parasite Plasmodium gallinaceum causes marked structural changes on the surface of its host erythrocyte.

Nagao E, Arie T, Dorward DW, Fairhurst RM, Dvorak JA.

J Struct Biol. 2008 Jun;162(3):460-7. doi: 10.1016/j.jsb.2008.03.005. Epub 2008 Mar 21.

39.

Ultrastructural analysis of bacteria-host cell interactions.

Dorward DW.

Methods Mol Biol. 2008;431:173-87.

PMID:
18287756
40.

Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA.

Wang R, Braughton KR, Kretschmer D, Bach TH, Queck SY, Li M, Kennedy AD, Dorward DW, Klebanoff SJ, Peschel A, DeLeo FR, Otto M.

Nat Med. 2007 Dec;13(12):1510-4. Epub 2007 Nov 11.

PMID:
17994102
41.

Genome sequence analysis of the emerging human pathogenic acetic acid bacterium Granulibacter bethesdensis.

Greenberg DE, Porcella SF, Zelazny AM, Virtaneva K, Sturdevant DE, Kupko JJ 3rd, Barbian KD, Babar A, Dorward DW, Holland SM.

J Bacteriol. 2007 Dec;189(23):8727-36. Epub 2007 Sep 7.

42.

Immunization of primates with a Newcastle disease virus-vectored vaccine via the respiratory tract induces a high titer of serum neutralizing antibodies against highly pathogenic avian influenza virus.

DiNapoli JM, Yang L, Suguitan A Jr, Elankumaran S, Dorward DW, Murphy BR, Samal SK, Collins PL, Bukreyev A.

J Virol. 2007 Nov;81(21):11560-8. Epub 2007 Aug 22.

43.

Ultrasensitive detection of scrapie prion protein using seeded conversion of recombinant prion protein.

Atarashi R, Moore RA, Sim VL, Hughson AG, Dorward DW, Onwubiko HA, Priola SA, Caughey B.

Nat Methods. 2007 Aug;4(8):645-50. Epub 2007 Jul 22.

PMID:
17643109
44.

Dectin-1 promotes fungicidal activity of human neutrophils.

Kennedy AD, Willment JA, Dorward DW, Williams DL, Brown GD, DeLeo FR.

Eur J Immunol. 2007 Feb;37(2):467-78.

45.

Is Panton-Valentine leukocidin the major virulence determinant in community-associated methicillin-resistant Staphylococcus aureus disease?

Voyich JM, Otto M, Mathema B, Braughton KR, Whitney AR, Welty D, Long RD, Dorward DW, Gardner DJ, Lina G, Kreiswirth BN, DeLeo FR.

J Infect Dis. 2006 Dec 15;194(12):1761-70. Epub 2006 Nov 2.

PMID:
17109350
46.

A novel bacterium associated with lymphadenitis in a patient with chronic granulomatous disease.

Greenberg DE, Ding L, Zelazny AM, Stock F, Wong A, Anderson VL, Miller G, Kleiner DE, Tenorio AR, Brinster L, Dorward DW, Murray PR, Holland SM.

PLoS Pathog. 2006 Apr;2(4):e28. Epub 2006 Apr 14.

47.

Inhibition of chlamydiae by primary alcohols correlates with the strain-specific complement of plasticity zone phospholipase D genes.

Nelson DE, Crane DD, Taylor LD, Dorward DW, Goheen MM, Caldwell HD.

Infect Immun. 2006 Jan;74(1):73-80.

48.

Insights into mechanisms used by Staphylococcus aureus to avoid destruction by human neutrophils.

Voyich JM, Braughton KR, Sturdevant DE, Whitney AR, Saïd-Salim B, Porcella SF, Long RD, Dorward DW, Gardner DJ, Kreiswirth BN, Musser JM, DeLeo FR.

J Immunol. 2005 Sep 15;175(6):3907-19.

49.

Genome-wide protective response used by group A Streptococcus to evade destruction by human polymorphonuclear leukocytes.

Voyich JM, Sturdevant DE, Braughton KR, Kobayashi SD, Lei B, Virtaneva K, Dorward DW, Musser JM, DeLeo FR.

Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1996-2001. Epub 2003 Feb 6.

50.

Staphylococcus aureus aconitase inactivation unexpectedly inhibits post-exponential-phase growth and enhances stationary-phase survival.

Somerville GA, Chaussee MS, Morgan CI, Fitzgerald JR, Dorward DW, Reitzer LJ, Musser JM.

Infect Immun. 2002 Nov;70(11):6373-82.

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