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Items: 25


Knockdown of T-bet expression in Mart-127-35 -specific T-cell-receptor-engineered human CD4(+)  CD25(-) and CD8(+) T cells attenuates effector function.

Jha SS, Chakraborty NG, Singh P, Mukherji B, Dorsky DI.

Immunology. 2015 May;145(1):124-35. doi: 10.1111/imm.12431.


The HIVToolbox 2 web system integrates sequence, structure, function and mutation analysis.

Sargeant DP, Deverasetty S, Strong CL, Alaniz IJ, Bartlett A, Brandon NR, Brooks SB, Brown FA, Bufi F, Chakarova M, David RP, Dobritch KM, Guerra HP, Hedden MW, Kumra R, Levitt KS, Mathew KR, Matti R, Maza DQ, Mistry S, Novakovic N, Pomerantz A, Portillo J, Rafalski TF, Rathnayake VR, Rezapour N, Songao S, Tuggle SL, Yousif S, Dorsky DI, Schiller MR.

PLoS One. 2014 Jun 2;9(6):e98810. doi: 10.1371/journal.pone.0098810. eCollection 2014.


MHC-I-restricted melanoma antigen specific TCR-engineered human CD4+ T cells exhibit multifunctional effector and helper responses, in vitro.

Ray S, Chhabra A, Chakraborty NG, Hegde U, Dorsky DI, Chodon T, von Euw E, Comin-Anduix B, Koya RC, Ribas A, Economou JS, Rosenberg SA, Mukherji B; UCLA-CALTECH-CHLA-USC-UCONN Consortium on Translational Program in Engineered Immunity.

Clin Immunol. 2010 Sep;136(3):338-47. doi: 10.1016/j.clim.2010.04.013. Epub 2010 May 23.


CD4+CD25- T cells transduced to express MHC class I-restricted epitope-specific TCR synthesize Th1 cytokines and exhibit MHC class I-restricted cytolytic effector function in a human melanoma model.

Chhabra A, Yang L, Wang P, Comin-Anduix B, Das R, Chakraborty NG, Ray S, Mehrotra S, Yang H, Hardee CL, Hollis R, Dorsky DI, Koya R, Kohn DB, Ribas A, Economou JS, Baltimore D, Mukherji B.

J Immunol. 2008 Jul 15;181(2):1063-70.


Activation-induced cell death of human melanoma specific cytotoxic T lymphocytes is mediated by apoptosis-inducing factor.

Chhabra A, Mehrotra S, Chakraborty NG, Dorsky DI, Mukherji B.

Eur J Immunol. 2006 Dec;36(12):3167-74.


Antigen presentation by MART-1 adenovirus-transduced interleukin-10-polarized human monocyte-derived dendritic cells.

Mehrotra S, Chhabra A, Chakraborty A, Chattopadhyay S, Slowik M, Stevens R, Zengou R, Mathias C, Butterfield LH, Dorsky DI, Economou JS, Mukherji B, Chakraborty NG.

Immunology. 2004 Dec;113(4):472-81.


Rescuing melanoma epitope-specific cytolytic T lymphocytes from activation-induced cell death, by SP600125, an inhibitor of JNK: implications in cancer immunotherapy.

Mehrotra S, Chhabra A, Chattopadhyay S, Dorsky DI, Chakraborty NG, Mukherji B.

J Immunol. 2004 Nov 15;173(10):6017-24.


Enhancement of implantable glucose sensor function in vivo using gene transfer-induced neovascularization.

Klueh U, Dorsky DI, Kreutzer DL.

Biomaterials. 2005 Apr;26(10):1155-63.


Cross-presentation of a human tumor antigen delivered to dendritic cells by HSV VP22-mediated protein translocation.

Chhabra A, Mehrotra S, Chakraborty NG, Mukherji B, Dorsky DI.

Eur J Immunol. 2004 Oct;34(10):2824-33.


Use of vascular endothelial cell growth factor gene transfer to enhance implantable sensor function in vivo.

Klueh U, Dorsky DI, Kreutzer DL.

J Biomed Mater Res A. 2003 Dec 15;67(4):1072-86.


Ex ova chick chorioallantoic membrane as a novel model for evaluation of tissue responses to biomaterials and implants.

Klueh U, Dorsky DI, Moussy F, Kreutzer DL.

J Biomed Mater Res A. 2003 Dec 1;67(3):838-43.


Regulation of melanoma epitope-specific cytolytic T lymphocyte response by immature and activated dendritic cells, in vitro.

Mehrotra S, Stevens R, Zengou R, Chakraborty NG, Butterfield LH, Economou JS, Dorsky DI, Mukherji B.

Cancer Res. 2003 Sep 1;63(17):5607-14.


Detection of HIV-1 infection with a green fluorescent protein reporter system.

Dorsky DI, Wells M, Harrington RD.

J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Dec 1;13(4):308-13.


Human eosinophils express CD4 protein and bind human immunodeficiency virus 1 gp120.

Lucey DR, Dorsky DI, Nicholson-Weller A, Weller PF.

J Exp Med. 1989 Jan 1;169(1):327-32.


Expression of herpes simplex virus type 1 DNA polymerase in Saccharomyces cerevisiae and detection of virus-specific enzyme activity in cell-free lysates.

Haffey ML, Stevens JT, Terry BJ, Dorsky DI, Crumpacker CS, Wietstock SM, Ruyechan WT, Field AK.

J Virol. 1988 Dec;62(12):4493-8.


Drugs five years later: acyclovir.

Dorsky DI, Crumpacker CS.

Ann Intern Med. 1987 Dec;107(6):859-74. Review.


Carboxy terminus of polyoma middle-sized tumor antigen is required for attachment to membranes, associated protein kinase activities, and cell transformation.

Carmichael GG, Schaffhausen BS, Dorsky DI, Oliver DB, Benjamin TL.

Proc Natl Acad Sci U S A. 1982 Jun;79(11):3579-83.

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