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Items: 1 to 50 of 131

1.

Do haematopoietic stem cells age?

Dorshkind K, Höfer T, Montecino-Rodriguez E, Pioli PD, Rodewald HR.

Nat Rev Immunol. 2019 Nov 18. doi: 10.1038/s41577-019-0236-2. [Epub ahead of print] Review.

PMID:
31740804
2.

Plasma Cells Are Obligate Effectors of Enhanced Myelopoiesis in Aging Bone Marrow.

Pioli PD, Casero D, Montecino-Rodriguez E, Morrison SL, Dorshkind K.

Immunity. 2019 Aug 20;51(2):351-366.e6. doi: 10.1016/j.immuni.2019.06.006. Epub 2019 Jul 11.

PMID:
31303400
3.

B1 B cell progenitors.

Ghosn E, Dorshkind K, Herzenberg LA, Holodick N, Kantor A, Montecino-Rodriguez E, Rothstein TL, Silverman GJ, Yang Y, Yoder MC, Yoshimoto M.

Science. 2019 Apr 19;364(6437):248. doi: 10.1126/science.aax6784. Epub 2019 Apr 18. No abstract available.

PMID:
31000655
4.

Lymphoid-Biased Hematopoietic Stem Cells Are Maintained with Age and Efficiently Generate Lymphoid Progeny.

Montecino-Rodriguez E, Kong Y, Casero D, Rouault A, Dorshkind K, Pioli PD.

Stem Cell Reports. 2019 Mar 5;12(3):584-596. doi: 10.1016/j.stemcr.2019.01.016. Epub 2019 Feb 21.

5.

Differential Expression of PU.1 and Key T Lineage Transcription Factors Distinguishes Fetal and Adult T Cell Development.

Montecino-Rodriguez E, Casero D, Fice M, Le J, Dorshkind K.

J Immunol. 2018 Mar 15;200(6):2046-2056. doi: 10.4049/jimmunol.1701336. Epub 2018 Feb 7.

6.

Distinct Genetic Networks Orchestrate the Emergence of Specific Waves of Fetal and Adult B-1 and B-2 Development.

Montecino-Rodriguez E, Fice M, Casero D, Berent-Maoz B, Barber CL, Dorshkind K.

Immunity. 2016 Sep 20;45(3):527-539. doi: 10.1016/j.immuni.2016.07.012. Epub 2016 Aug 23.

7.

The expansion of thymopoiesis in neonatal mice is dependent on expression of high mobility group a 2 protein (Hmga2).

Berent-Maoz B, Montecino-Rodriguez E, Fice M, Casero D, Seet CS, Crooks GM, Lowry W, Dorshkind K.

PLoS One. 2015 May 1;10(5):e0125414. doi: 10.1371/journal.pone.0125414. eCollection 2015.

8.

Murine B-1 B cell progenitors initiate B-acute lymphoblastic leukemia with features of high-risk disease.

Montecino-Rodriguez E, Li K, Fice M, Dorshkind K.

J Immunol. 2014 Jun 1;192(11):5171-8. doi: 10.4049/jimmunol.1303170. Epub 2014 Apr 21.

9.

Shared signaling systems in myeloid cell-mediated muscle regeneration.

Tidball JG, Dorshkind K, Wehling-Henricks M.

Development. 2014 Mar;141(6):1184-96. doi: 10.1242/dev.098285. Review.

10.

Causes, consequences, and reversal of immune system aging.

Montecino-Rodriguez E, Berent-Maoz B, Dorshkind K.

J Clin Invest. 2013 Mar;123(3):958-65. doi: 10.1172/JCI64096. Epub 2013 Mar 1. Review.

11.

Genetic regulation of thymocyte progenitor aging.

Berent-Maoz B, Montecino-Rodriguez E, Dorshkind K.

Semin Immunol. 2012 Oct;24(5):303-8. doi: 10.1016/j.smim.2012.04.006. Epub 2012 May 2. Review.

12.

Fibroblast growth factor-7 partially reverses murine thymocyte progenitor aging by repression of Ink4a.

Berent-Maoz B, Montecino-Rodriguez E, Signer RA, Dorshkind K.

Blood. 2012 Jun 14;119(24):5715-21. doi: 10.1182/blood-2011-12-400002. Epub 2012 May 3.

13.

B-1 B cell development in the fetus and adult.

Montecino-Rodriguez E, Dorshkind K.

Immunity. 2012 Jan 27;36(1):13-21. doi: 10.1016/j.immuni.2011.11.017. Review.

14.

Developmental relationships between B-1 and B-2 progenitors.

Barber CL, Montecino-Rodriguez E, Dorshkind K.

Cell Cycle. 2011 Nov 15;10(22):3810-1. doi: 10.4161/cc.10.22.18190. Epub 2011 Nov 15. No abstract available.

15.

Formation of B-1 B cells from neonatal B-1 transitional cells exhibits NF-κB redundancy.

Montecino-Rodriguez E, Dorshkind K.

J Immunol. 2011 Dec 1;187(11):5712-9. doi: 10.4049/jimmunol.1102416. Epub 2011 Oct 26.

16.

Reduced production of B-1-specified common lymphoid progenitors results in diminished potential of adult marrow to generate B-1 cells.

Barber CL, Montecino-Rodriguez E, Dorshkind K.

Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13700-4. doi: 10.1073/pnas.1107172108. Epub 2011 Aug 1.

17.

Embryonic day 9 yolk sac and intra-embryonic hemogenic endothelium independently generate a B-1 and marginal zone progenitor lacking B-2 potential.

Yoshimoto M, Montecino-Rodriguez E, Ferkowicz MJ, Porayette P, Shelley WC, Conway SJ, Dorshkind K, Yoder MC.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1468-73. doi: 10.1073/pnas.1015841108. Epub 2011 Jan 5.

18.

Not a split decision for human hematopoiesis.

Dorshkind K.

Nat Immunol. 2010 Jul;11(7):569-70. doi: 10.1038/ni0710-569. No abstract available.

PMID:
20562840
19.

Immature B-cell progenitors survive oncogenic stress and efficiently initiate Ph+ B-acute lymphoblastic leukemia.

Signer RA, Montecino-Rodriguez E, Witte ON, Dorshkind K.

Blood. 2010 Oct 7;116(14):2522-30. doi: 10.1182/blood-2010-01-264093. Epub 2010 Jun 18.

20.

Age-associated declines in immune system development and function: causes, consequences, and reversal.

Dorshkind K, Swain S.

Curr Opin Immunol. 2009 Aug;21(4):404-7. doi: 10.1016/j.coi.2009.07.001. Epub 2009 Jul 23. No abstract available.

21.

The ageing immune system: is it ever too old to become young again?

Dorshkind K, Montecino-Rodriguez E, Signer RA.

Nat Rev Immunol. 2009 Jan;9(1):57-62. doi: 10.1038/nri2471. Review.

PMID:
19104499
22.

Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16Ink4a and Arf.

Signer RA, Montecino-Rodriguez E, Witte ON, Dorshkind K.

Genes Dev. 2008 Nov 15;22(22):3115-20. doi: 10.1101/gad.1715808.

23.

Linking the hematopoietic microenvironment to imatinib-resistant Ph+ B-ALL.

Dorshkind K, Witte ON.

Genes Dev. 2007 Sep 15;21(18):2249-52. No abstract available.

24.

Fate decisions regulating bone marrow and peripheral B lymphocyte development.

Monroe JG, Dorshkind K.

Adv Immunol. 2007;95:1-50. Review.

PMID:
17869609
25.

Generation of functionally distinct B lymphocytes from common myeloid progenitors.

Yang GX, Lian ZX, Chuang YH, Shu SA, Moritoki Y, Lan R, Wakabayashi K, Ansari AA, Dorshkind K, Ikehara S, Gershwin ME.

Clin Exp Immunol. 2007 Nov;150(2):349-57. Epub 2007 Sep 5.

26.

The protean nature of cells in the B lymphocyte lineage.

Hardy RR, Kincade PW, Dorshkind K.

Immunity. 2007 Jun;26(6):703-14. Review.

27.

Age-related defects in B lymphopoiesis underlie the myeloid dominance of adult leukemia.

Signer RA, Montecino-Rodriguez E, Witte ON, McLaughlin J, Dorshkind K.

Blood. 2007 Sep 15;110(6):1831-9. Epub 2007 Jun 6.

28.

Stromal cell-dependent growth of B-1 B cell progenitors in the absence of direct contact.

Montecino-Rodriguez E, Dorshkind K.

Nat Protoc. 2006;1(3):1140-4.

PMID:
17406395
29.

Fetal B-cell lymphopoiesis and the emergence of B-1-cell potential.

Dorshkind K, Montecino-Rodriguez E.

Nat Rev Immunol. 2007 Mar;7(3):213-9. Review.

PMID:
17318232
30.

Aging, B lymphopoiesis, and patterns of leukemogenesis.

Signer RA, Montecino-Rodriguez E, Dorshkind K.

Exp Gerontol. 2007 May;42(5):391-5. Epub 2006 Dec 20. Review.

31.

New perspectives in B-1 B cell development and function.

Montecino-Rodriguez E, Dorshkind K.

Trends Immunol. 2006 Sep;27(9):428-33. Epub 2006 Jul 24. Review.

PMID:
16861037
32.

Evolving patterns of lymphopoiesis from embryogenesis through senescence.

Montecino-Rodriguez E, Dorshkind K.

Immunity. 2006 Jun;24(6):659-62. Review. Erratum in: Immunity. 2006 Jul;25(1):177.

33.

Hematopoiesis flies high with Ikaros.

Smale ST, Dorshkind K.

Nat Immunol. 2006 Apr;7(4):367-9. No abstract available.

PMID:
16550201
34.

Identification of a B-1 B cell-specified progenitor.

Montecino-Rodriguez E, Leathers H, Dorshkind K.

Nat Immunol. 2006 Mar;7(3):293-301. Epub 2006 Jan 22.

PMID:
16429139
35.

Effects of aging on the common lymphoid progenitor to pro-B cell transition.

Min H, Montecino-Rodriguez E, Dorshkind K.

J Immunol. 2006 Jan 15;176(2):1007-12.

36.

Reassessing the role of growth hormone and sex steroids in thymic involution.

Min H, Montecino-Rodriguez E, Dorshkind K.

Clin Immunol. 2006 Jan;118(1):117-23. Epub 2005 Sep 26.

PMID:
16188505
37.

Transgenic expression of Helios in B lineage cells alters B cell properties and promotes lymphomagenesis.

Dovat S, Montecino-Rodriguez E, Schuman V, Teitell MA, Dorshkind K, Smale ST.

J Immunol. 2005 Sep 15;175(6):3508-15.

38.

Reevaluating current models of thymic involution.

Montecino-Rodriquez E, Min H, Dorshkind K.

Semin Immunol. 2005 Oct;17(5):356-61. Review.

PMID:
15967677
39.

Effects of aging on early B- and T-cell development.

Min H, Montecino-Rodriguez E, Dorshkind K.

Immunol Rev. 2005 Jun;205:7-17. Review.

PMID:
15882341
40.

Reduction in the developmental potential of intrathymic T cell progenitors with age.

Min H, Montecino-Rodriguez E, Dorshkind K.

J Immunol. 2004 Jul 1;173(1):245-50.

41.

Macrophages and stromal cells phagocytose apoptotic bone marrow-derived B lineage cells.

Dogusan Z, Montecino-Rodriguez E, Dorshkind K.

J Immunol. 2004 Apr 15;172(8):4717-23.

42.

Got MLL? Definitive hematopoiesis requires MLL gene expression.

Dorshkind K, Witte O.

Mol Cell. 2004 Mar 26;13(6):765-6.

43.

Age-related changes in lymphocyte development and function.

Linton PJ, Dorshkind K.

Nat Immunol. 2004 Feb;5(2):133-9. Review.

PMID:
14749784
44.

Effects of housing on the thymic deficiency in dwarf mice and its reversal by growth hormone administration.

Dorshkind K, Welniak L, Gault RA, Hixon J, Montecino-Rodriguez E, Horseman ND, Gertner JM, Murphy WJ.

Clin Immunol. 2003 Nov;109(2):197-202.

PMID:
14597218
45.

To T or not to T: reassessing the common lymphoid progenitor.

Montecino-Rodriguez E, Dorshkind K.

Nat Immunol. 2003 Feb;4(2):100-1. No abstract available.

PMID:
12555090
46.

Identification of B/macrophage progenitors in adult bone marrow.

Montecino-Rodriguez E, Dorshkind K.

Semin Immunol. 2002 Dec;14(6):371-6. Review.

PMID:
12457609
47.

B-cell development in the thymus is limited by inhibitory signals from the thymic microenvironment.

Hashimoto Y, Montecino-Rodriguez E, Leathers H, Stephan RP, Dorshkind K.

Blood. 2002 Nov 15;100(10):3504-11. Epub 2002 Jul 5.

PMID:
12393710
48.

Stem cells and lineage plasticity: the challenge to existing paradigms.

Dorshkind K.

Immunol Rev. 2002 Sep;187:5-8. Review. No abstract available.

PMID:
12366678
49.

Increased frequency of pre-pro B cells in the bone marrow of New Zealand Black (NZB) mice: implications for a developmental block in B cell differentiation.

Lian ZX, Kita H, Okada T, Hsu T, Shultz LD, Dorshkind K, Ansari AA, Ikehara S, Naiki M, Gershwin ME.

Dev Immunol. 2002 Mar;9(1):35-45.

50.

Age-related alterations in the lymphohematopoietic and B-lineage precursor populations in NZB mice.

Lian ZX, Okada T, Kita H, Hsu T, Shultz LD, Dorshkind K, Ansari AA, Naiki M, Ikehara S, Gershwin ME.

Stem Cells. 2002;20(4):293-300.

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