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Items: 8

1.

Tacrolimus troughs and genetic determinants of metabolism in kidney transplant recipients: A comparison of four ancestry groups.

Mohamed ME, Schladt DP, Guan W, Wu B, van Setten J, Keating BJ, Iklé D, Remmel RP, Dorr CR, Mannon RB, Matas AJ, Israni AK, Oetting WS, Jacobson PA; DeKAF Genomics and GEN03 Investigators.

Am J Transplant. 2019 Apr 6. doi: 10.1111/ajt.15385. [Epub ahead of print]

PMID:
30953600
2.

Genetic Variants Associated With Immunosuppressant Pharmacokinetics and Adverse Effects in the DeKAF Genomics Genome-wide Association Studies.

Oetting WS, Wu B, Schladt DP, Guan W, van Setten J, Keating BJ, Iklé D, Remmel RP, Dorr CR, Mannon RB, Matas AJ, Israni AK, Jacobson PA; DeKAF Genomics and GEN-03 Investigators.

Transplantation. 2019 Jun;103(6):1131-1139. doi: 10.1097/TP.0000000000002625.

PMID:
30801552
3.

Analysis of 75 Candidate SNPs Associated with Acute Rejection in Kidney Transplant Recipients: Validation of rs2910164 in MicroRNA MIR146A.

Oetting WS, Schladt DP, Dorr CR, Wu B, Guan W, Remmel RP, Iklé D, Mannon RB, Matas AJ, Israni AK, Jacobson PA; DeKAF Genomics and GEN03 Investigators.

Transplantation. 2019 Feb 11. doi: 10.1097/TP.0000000000002659. [Epub ahead of print]

PMID:
30801535
4.

Identification of genetic variants associated with tacrolimus metabolism in kidney transplant recipients by extreme phenotype sampling and next generation sequencing.

Dorr CR, Wu B, Remmel RP, Muthusamy A, Schladt DP, Abrahante JE, Guan W, Mannon RB, Matas AJ, Oetting WS, Jacobson PA, Israni AK; for DeKAF Genomics.

Pharmacogenomics J. 2018 Nov 16. doi: 10.1038/s41397-018-0063-z. [Epub ahead of print]

5.

Genetics of acute rejection after kidney transplantation.

Dorr CR, Oetting WS, Jacobson PA, Israni AK.

Transpl Int. 2018 Mar;31(3):263-277. doi: 10.1111/tri.13084. Epub 2017 Nov 8. Review.

6.

CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism.

Dorr CR, Remmel RP, Muthusamy A, Fisher J, Moriarity BS, Yasuda K, Wu B, Guan W, Schuetz EG, Oetting WS, Jacobson PA, Israni AK.

Drug Metab Dispos. 2017 Aug;45(8):957-965. doi: 10.1124/dmd.117.076307. Epub 2017 May 22.

7.

Deceased-Donor Apolipoprotein L1 Renal-Risk Variants Have Minimal Effects on Liver Transplant Outcomes.

Dorr CR, Freedman BI, Hicks PJ, Brown WM, Russell GB, Julian BA, Pastan SO, Gautreaux MD, Muthusamy A, Chinnakotla S, Hauptfeld V, Bray RA, Kirk AD, Divers J, Israni AK.

PLoS One. 2016 Apr 7;11(4):e0152775. doi: 10.1371/journal.pone.0152775. eCollection 2016.

8.

Triterpene derivatives that inhibit human immunodeficiency virus type 1 replication.

Dorr CR, Yemets S, Kolomitsyna O, Krasutsky P, Mansky LM.

Bioorg Med Chem Lett. 2011 Jan 1;21(1):542-5. doi: 10.1016/j.bmcl.2010.10.078.

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