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Items: 30


Microbial ecology perturbation in human IgA deficiency.

Fadlallah J, El Kafsi H, Sterlin D, Juste C, Parizot C, Dorgham K, Autaa G, Gouas D, Almeida M, Lepage P, Pons N, Le Chatelier E, Levenez F, Kennedy S, Galleron N, de Barros JP, Malphettes M, Galicier L, Boutboul D, Mathian A, Miyara M, Oksenhendler E, Amoura Z, Doré J, Fieschi C, Ehrlich SD, Larsen M, Gorochov G.

Sci Transl Med. 2018 May 2;10(439). pii: eaan1217. doi: 10.1126/scitranslmed.aan1217.


Involvement of NK Cells and NKp30 Pathway in Antisynthetase Syndrome.

Hervier B, Perez M, Allenbach Y, Devilliers H, Cohen F, Uzunhan Y, Ouakrim H, Dorgham K, Méritet JF, Longchampt E, Stenzel W, Cremer I, Benveniste O, Vieillard V.

J Immunol. 2016 Sep 1;197(5):1621-30. doi: 10.4049/jimmunol.1501902. Epub 2016 Aug 10.


Identification of the Single Immunodominant Region of the Native Human CC Chemokine Receptor 6 Recognized by Mouse Monoclonal Antibodies.

Dorgham K, Dejou C, Piesse C, Gorochov G, Pène J, Yssel H.

PLoS One. 2016 Jun 23;11(6):e0157740. doi: 10.1371/journal.pone.0157740. eCollection 2016.


ECL1i, d(LGTFLKC), a novel, small peptide that specifically inhibits CCL2-dependent migration.

Auvynet C, Baudesson de Chanville C, Hermand P, Dorgham K, Piesse C, Pouchy C, Carlier L, Poupel L, Barthélémy S, Felouzis V, Lacombe C, Sagan S, Chemtob S, Quiniou C, Salomon B, Deterre P, Sennlaub F, Combadière C.

FASEB J. 2016 Jun;30(6):2370-81. doi: 10.1096/fj.201500116. Epub 2016 Mar 15. Erratum in: FASEB J. 2017 Feb;31(2):852.


Generating Chemokine Analogs with Enhanced Pharmacological Properties Using Phage Display.

Dorgham K, Cerini F, Gaertner H, Melotti A, Rossitto-Borlat I, Gorochov G, Hartley O.

Methods Enzymol. 2016;570:47-72. doi: 10.1016/bs.mie.2015.09.014. Epub 2015 Nov 14.


HIV-Infected Spleens Present Altered Follicular Helper T Cell (Tfh) Subsets and Skewed B Cell Maturation.

Colineau L, Rouers A, Yamamoto T, Xu Y, Urrutia A, Pham HP, Cardinaud S, Samri A, Dorgham K, Coulon PG, Cheynier R, Hosmalin A, Oksenhendler E, Six A, Kelleher AD, Zaunders J, Koup RA, Autran B, Moris A, Graff-Dubois S.

PLoS One. 2015 Oct 26;10(10):e0140978. doi: 10.1371/journal.pone.0140978. eCollection 2015.


Gene transfer of two entry inhibitors protects CD4⁺ T cell from HIV-1 infection in humanized mice.

Petit NY, Baillou C, Burlion A, Dorgham K, Levacher B, Amiel C, Schneider V, Lemoine FM, Gorochov G, Marodon G.

Gene Ther. 2016 Feb;23(2):144-50. doi: 10.1038/gt.2015.101. Epub 2015 Oct 21.


Ultraviolet light converts propranolol, a nonselective β-blocker and potential lupus-inducing drug, into a proinflammatory AhR ligand.

Dorgham K, Amoura Z, Parizot C, Arnaud L, Frances C, Pionneau C, Devilliers H, Pinto S, Zoorob R, Miyara M, Larsen M, Yssel H, Gorochov G, Mathian A.

Eur J Immunol. 2015 Nov;45(11):3174-87. doi: 10.1002/eji.201445144. Epub 2015 Oct 16.


Targeting both viral and host determinants of human immunodeficiency virus entry, using a new lentiviral vector coexpressing the T20 fusion inhibitor and a selective CCL5 intrakine.

Petit N, Dorgham K, Levacher B, Burlion A, Gorochov G, Marodon G.

Hum Gene Ther Methods. 2014 Aug;25(4):232-40. doi: 10.1089/hgtb.2014.034.


Identification of a cellular ligand for the natural cytotoxicity receptor NKp44.

Baychelier F, Sennepin A, Ermonval M, Dorgham K, Debré P, Vieillard V.

Blood. 2013 Oct 24;122(17):2935-42. doi: 10.1182/blood-2013-03-489054. Epub 2013 Aug 19.


Pharmacological inhibition of the chemokine receptor, CX3CR1, reduces atherosclerosis in mice.

Poupel L, Boissonnas A, Hermand P, Dorgham K, Guyon E, Auvynet C, Charles FS, Lesnik P, Deterre P, Combadiere C.

Arterioscler Thromb Vasc Biol. 2013 Oct;33(10):2297-305. doi: 10.1161/ATVBAHA.112.300930. Epub 2013 Jul 25.


CX3CR1 reduces Ly6Chigh-monocyte motility within and release from the bone marrow after chemotherapy in mice.

Jacquelin S, Licata F, Dorgham K, Hermand P, Poupel L, Guyon E, Deterre P, Hume DA, Combadière C, Boissonnas A.

Blood. 2013 Aug 1;122(5):674-83. doi: 10.1182/blood-2013-01-480749. Epub 2013 Jun 17.


Specific targeting of caspase-9/PP2A interaction as potential new anti-cancer therapy.

Arrouss I, Nemati F, Roncal F, Wislez M, Dorgham K, Vallerand D, Rabbe N, Karboul N, Carlotti F, Bravo J, Mazier D, Decaudin D, Rebollo A.

PLoS One. 2013 Apr 23;8(4):e60816. doi: 10.1371/journal.pone.0060816. Print 2013.


Role of CX3CR1 receptor in monocyte/macrophage driven neovascularization.

Kumar AH, Martin K, Turner EC, Buneker CK, Dorgham K, Deterre P, Caplice NM.

PLoS One. 2013;8(2):e57230. doi: 10.1371/journal.pone.0057230. Epub 2013 Feb 21.


Activated and resting regulatory T cell exhaustion concurs with high levels of interleukin-22 expression in systemic sclerosis lesions.

Mathian A, Parizot C, Dorgham K, Trad S, Arnaud L, Larsen M, Miyara M, Hié M, Piette JC, Frances C, Yssel H, Amoura Z, Gorochov G.

Ann Rheum Dis. 2012 Jul;71(7):1227-34. doi: 10.1136/annrheumdis-2011-200709.


Exhausted cytotoxic control of Epstein-Barr virus in human lupus.

Larsen M, Sauce D, Deback C, Arnaud L, Mathian A, Miyara M, Boutolleau D, Parizot C, Dorgham K, Papagno L, Appay V, Amoura Z, Gorochov G.

PLoS Pathog. 2011 Oct;7(10):e1002328. doi: 10.1371/journal.ppat.1002328. Epub 2011 Oct 20.


CD4+ T cell depletion in human immunodeficiency virus (HIV) infection: role of apoptosis.

Février M, Dorgham K, Rebollo A.

Viruses. 2011 May;3(5):586-612. doi: 10.3390/v3050586. Epub 2011 May 12. Review.


Multiparameter grouping delineates heterogeneous populations of human IL-17 and/or IL-22 T-cell producers that share antigen specificities with other T-cell subsets.

Larsen M, Arnaud L, Hié M, Parizot C, Dorgham K, Shoukry M, Kemula M, Barete S, Derai D, Sauce D, Amoura Z, Pène J, Yssel H, Gorochov G.

Eur J Immunol. 2011 Sep;41(9):2596-605. doi: 10.1002/eji.201041131. Epub 2011 Aug 4.


CCL20 and β-defensin-2 induce arrest of human Th17 cells on inflamed endothelium in vitro under flow conditions.

Ghannam S, Dejou C, Pedretti N, Giot JP, Dorgham K, Boukhaddaoui H, Deleuze V, Bernard FX, Jorgensen C, Yssel H, Pène J.

J Immunol. 2011 Feb 1;186(3):1411-20. doi: 10.4049/jimmunol.1000597. Epub 2010 Dec 22.


[Cytokines and T cell differentiation in systemic sclerosis].

Trad S, Granel B, Parizot C, Dorgham K, Hanslik T, Marie I, Amoura Z.

Rev Med Interne. 2011 Aug;32(8):472-85. doi: 10.1016/j.revmed.2010.07.015. Epub 2010 Sep 17. Review. French.


Subtle conformational changes between CX3CR1 genetic variants as revealed by resonance energy transfer assays.

Darbandi-Tehrani K, Hermand P, Carvalho S, Dorgham K, Couvineau A, Lacapère JJ, Combadière C, Deterre P.

FASEB J. 2010 Nov;24(11):4585-98. doi: 10.1096/fj.10-156612. Epub 2010 Jul 28.


An engineered CX3CR1 antagonist endowed with anti-inflammatory activity.

Dorgham K, Ghadiri A, Hermand P, Rodero M, Poupel L, Iga M, Hartley O, Gorochov G, Combadière C, Deterre P.

J Leukoc Biol. 2009 Oct;86(4):903-11. doi: 10.1189/jlb.0308158. Epub 2009 Jul 1.


Engineered CCR5 superagonist chemokine as adjuvant in anti-tumor DNA vaccination.

Dorgham K, Abadie V, Iga M, Hartley O, Gorochov G, Combadière B.

Vaccine. 2008 Jun 19;26(26):3252-60. doi: 10.1016/j.vaccine.2008.04.003. Epub 2008 Apr 24.


Prominent plasmacytosis following intravenous immunoglobulin correlates with clinical improvement in Guillain-Barré syndrome.

Mori I, Parizot C, Dorgham K, Demeret S, Amoura Z, Bolgert F, Gorochov G.

PLoS One. 2008 May 7;3(5):e2109. doi: 10.1371/journal.pone.0002109.


The immune paradox of sarcoidosis and regulatory T cells.

Miyara M, Amoura Z, Parizot C, Badoual C, Dorgham K, Trad S, Kambouchner M, Valeyre D, Chapelon-Abric C, Debré P, Piette JC, Gorochov G.

J Exp Med. 2006 Feb 20;203(2):359-70. Epub 2006 Jan 23. Erratum in: J Exp Med. 2006 Feb 20;203(2):477.


Global natural regulatory T cell depletion in active systemic lupus erythematosus.

Miyara M, Amoura Z, Parizot C, Badoual C, Dorgham K, Trad S, Nochy D, Debré P, Piette JC, Gorochov G.

J Immunol. 2005 Dec 15;175(12):8392-400.


Immunogenicity of HIV type 1 gp120 CD4 binding site phage mimotopes.

Dorgham K, Dogan I, Bitton N, Parizot C, Cardona V, Debré P, Hartley O, Gorochov G.

AIDS Res Hum Retroviruses. 2005 Jan;21(1):82-92.


Phage-displayed libraries of peptide/major histocompatibility complexes.

Dogan I, Dorgham K, Chang HC, Parizot C, Lemaître F, Ferradini L, Reinherz EL, Debré P, Gorochov G.

Eur J Immunol. 2004 Feb;34(2):598-607.


Human immunodeficiency virus type 1 entry inhibitors selected on living cells from a library of phage chemokines.

Hartley O, Dorgham K, Perez-Bercoff D, Cerini F, Heimann A, Gaertner H, Offord RE, Pancino G, Debré P, Gorochov G.

J Virol. 2003 Jun;77(12):6637-44.


Effect of tyrosine kinase inhibitor STI571 on the kinase activity of wild-type and various mutated c-kit receptors found in mast cell neoplasms.

Zermati Y, De Sepulveda P, Féger F, Létard S, Kersual J, Castéran N, Gorochov G, Dy M, Ribadeau Dumas A, Dorgham K, Parizot C, Bieche Y, Vidaud M, Lortholary O, Arock M, Hermine O, Dubreuil P.

Oncogene. 2003 Feb 6;22(5):660-4.


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