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Items: 40

1.

A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis.

Mayo MJ, Pockros PJ, Jones D, Bowlus CL, Levy C, Patanwala I, Bacon B, Luketic V, Vuppalanchi R, Medendorp S, Dorenbaum A, Kennedy C, Novak P, Gu J, Apostol G, Hirschfield GM.

Hepatol Commun. 2019 Feb 1;3(3):365-381. doi: 10.1002/hep4.1305. eCollection 2019 Mar.

2.

Safety, tolerability and pharmacodynamics of apical sodium-dependent bile acid transporter inhibition with volixibat in healthy adults and patients with type 2 diabetes mellitus: a randomised placebo-controlled trial.

Tiessen RG, Kennedy CA, Keller BT, Levin N, Acevedo L, Gedulin B, van Vliet AA, Dorenbaum A, Palmer M.

BMC Gastroenterol. 2018 Jan 5;18(1):3. doi: 10.1186/s12876-017-0736-0.

3.

Rhinology Future Debates, an EUFOREA Report.

Fokkens WJ, Bachert C, Bernal-Sprekelsen M, Bousquet J, Djandji M, Dorenbaum A, Hakimi-Mehr D, Hendry S, Hopkins C, Leunig A, Mannent L, Mucha D, Onerci M, Pugin B, Toppila-Salmi S, Rowe P, Seys SF, Stimson S, Strzembosz A, Hellings PW.

Rhinology. 2017 Dec 1;55(4):298-304. doi: 10.4193/Rhin17.221.

PMID:
29166426
4.

Development of a Novel Tool to Assess the Impact of Itching in Pediatric Cholestasis.

Kamath BM, Abetz-Webb L, Kennedy C, Hepburn B, Gauthier M, Johnson N, Medendorp S, Dorenbaum A, Todorova L, Shneider BL.

Patient. 2018 Feb;11(1):69-82. doi: 10.1007/s40271-017-0266-4.

5.

Impact of asthma exacerbations and asthma triggers on asthma-related quality of life in patients with severe or difficult-to-treat asthma.

Luskin AT, Chipps BE, Rasouliyan L, Miller DP, Haselkorn T, Dorenbaum A.

J Allergy Clin Immunol Pract. 2014 Sep-Oct;2(5):544-52.e1-2. doi: 10.1016/j.jaip.2014.02.011. Epub 2014 Jul 3.

PMID:
25213047
6.

Single-dose, subcutaneous recombinant phenylalanine ammonia lyase conjugated with polyethylene glycol in adult patients with phenylketonuria: an open-label, multicentre, phase 1 dose-escalation trial.

Longo N, Harding CO, Burton BK, Grange DK, Vockley J, Wasserstein M, Rice GM, Dorenbaum A, Neuenburg JK, Musson DG, Gu Z, Sile S.

Lancet. 2014 Jul 5;384(9937):37-44. doi: 10.1016/S0140-6736(13)61841-3. Epub 2014 Apr 14.

7.

Clinical burden and predictors of asthma exacerbations in patients on guideline-based steps 4-6 asthma therapy in the TENOR cohort.

Calhoun WJ, Haselkorn T, Mink DR, Miller DP, Dorenbaum A, Zeiger RS.

J Allergy Clin Immunol Pract. 2014 Mar-Apr;2(2):193-200. doi: 10.1016/j.jaip.2013.11.013.

PMID:
24607048
8.

Phenotypes determined by cluster analysis in severe or difficult-to-treat asthma.

Schatz M, Hsu JW, Zeiger RS, Chen W, Dorenbaum A, Chipps BE, Haselkorn T.

J Allergy Clin Immunol. 2014 Jun;133(6):1549-56. doi: 10.1016/j.jaci.2013.10.006. Epub 2013 Dec 4.

PMID:
24315502
9.

Chaperone-like therapy with tetrahydrobiopterin in clinical trials for phenylketonuria: is genotype a predictor of response?

Sarkissian CN, Gamez A, Scott P, Dauvillier J, Dorenbaum A, Scriver CR, Stevens RC.

JIMD Rep. 2012;5:59-70. doi: 10.1007/8904_2011_96. Epub 2011 Dec 6.

10.

Assessment of asthma control and asthma exacerbations in the epidemiology and natural history of asthma: outcomes and treatment regimens (TENOR) observational cohort.

Chipps BE, Zeiger RS, Dorenbaum A, Borish L, Wenzel SE, Miller DP, Hayden ML, Bleecker ER, Simons FE, Szefler SJ, Weiss ST, Haselkorn T; TENOR Study Group.

Curr Respir Care Rep. 2012 Dec;1(4):259-269. Epub 2012 Sep 20.

11.

Safety of extended treatment with sapropterin dihydrochloride in patients with phenylketonuria: results of a phase 3b study.

Burton BK, Nowacka M, Hennermann JB, Lipson M, Grange DK, Chakrapani A, Trefz F, Dorenbaum A, Imperiale M, Kim SS, Fernhoff PM.

Mol Genet Metab. 2011 Aug;103(4):315-22. doi: 10.1016/j.ymgme.2011.03.020. Epub 2011 Mar 31.

PMID:
21646032
12.

Relative bioavailability of sapropterin from intact and dissolved sapropterin dihydrochloride tablets and the effects of food: a randomized, open-label, crossover study in healthy adults.

Musson DG, Kramer WG, Foehr ED, Bieberdorf FA, Hornfeldt CS, Kim SS, Dorenbaum A.

Clin Ther. 2010 Feb;32(2):338-46. doi: 10.1016/j.clinthera.2010.02.012.

PMID:
20206791
13.

Efficacy of sapropterin dihydrochloride in increasing phenylalanine tolerance in children with phenylketonuria: a phase III, randomized, double-blind, placebo-controlled study.

Trefz FK, Burton BK, Longo N, Casanova MM, Gruskin DJ, Dorenbaum A, Kakkis ED, Crombez EA, Grange DK, Harmatz P, Lipson MH, Milanowski A, Randolph LM, Vockley J, Whitley CB, Wolff JA, Bebchuk J, Christ-Schmidt H, Hennermann JB; Sapropterin Study Group.

J Pediatr. 2009 May;154(5):700-7. doi: 10.1016/j.jpeds.2008.11.040. Epub 2009 Mar 4.

PMID:
19261295
14.

Pharmacokinetics of sapropterin in patients with phenylketonuria.

Feillet F, Clarke L, Meli C, Lipson M, Morris AA, Harmatz P, Mould DR, Green B, Dorenbaum A, Giovannini M, Foehr E; Sapropterin Research Group.

Clin Pharmacokinet. 2008;47(12):817-25. doi: 10.2165/0003088-200847120-00006.

PMID:
19026037
15.

Safety and efficacy of 22 weeks of treatment with sapropterin dihydrochloride in patients with phenylketonuria.

Lee P, Treacy EP, Crombez E, Wasserstein M, Waber L, Wolff J, Wendel U, Dorenbaum A, Bebchuk J, Christ-Schmidt H, Seashore M, Giovannini M, Burton BK, Morris AA; Sapropterin Research Group.

Am J Med Genet A. 2008 Nov 15;146A(22):2851-9. doi: 10.1002/ajmg.a.32562.

PMID:
18932221
16.

The response of patients with phenylketonuria and elevated serum phenylalanine to treatment with oral sapropterin dihydrochloride (6R-tetrahydrobiopterin): a phase II, multicentre, open-label, screening study.

Burton BK, Grange DK, Milanowski A, Vockley G, Feillet F, Crombez EA, Abadie V, Harding CO, Cederbaum S, Dobbelaere D, Smith A, Dorenbaum A.

J Inherit Metab Dis. 2007 Oct;30(5):700-7. Epub 2007 Sep 12.

PMID:
17846916
17.

Pharmacokinetics of oral zidovudine administered during labour: a preliminary study.

Mirochnick M, Rodman JH, Robbins BL, Fridland A, Gandía J, Hitti J, Bardeguez A, Rathore MH, Gonzalez Garcia A, Cababasay M, Samson P, Mofenson L, Bryson YJ, Dorenbaum A.

HIV Med. 2007 Oct;8(7):451-6.

18.

Efficacy of sapropterin dihydrochloride (tetrahydrobiopterin, 6R-BH4) for reduction of phenylalanine concentration in patients with phenylketonuria: a phase III randomised placebo-controlled study.

Levy HL, Milanowski A, Chakrapani A, Cleary M, Lee P, Trefz FK, Whitley CB, Feillet F, Feigenbaum AS, Bebchuk JD, Christ-Schmidt H, Dorenbaum A; Sapropterin Research Group.

Lancet. 2007 Aug 11;370(9586):504-10.

PMID:
17693179
19.

Phenylalanine blood levels and clinical outcomes in phenylketonuria: a systematic literature review and meta-analysis.

Waisbren SE, Noel K, Fahrbach K, Cella C, Frame D, Dorenbaum A, Levy H.

Mol Genet Metab. 2007 Sep-Oct;92(1-2):63-70. Epub 2007 Jun 25.

PMID:
17591452
20.

Efficacy and safety of heparinase I versus protamine in patients undergoing coronary artery bypass grafting with and without cardiopulmonary bypass.

Stafford-Smith M, Lefrak EA, Qazi AG, Welsby IJ, Barber L, Hoeft A, Dorenbaum A, Mathias J, Rochon JJ, Newman MF; Members of the Global Perioperative Research Organization.

Anesthesiology. 2005 Aug;103(2):229-40.

PMID:
16052104
21.

The impact of race/ethnicity on mother-to-child HIV transmission in the United States in Pediatric AIDS Clinical Trials Group Protocol 316.

Cunningham CK, Balasubramanian R, Delke I, Maupin R, Mofenson L, Dorenbaum A, Sullivan JL, Gonzalez-Garcia A, Thorpe E, Rathore M, Gelber RD.

J Acquir Immune Defic Syndr. 2004 Jul 1;36(3):800-7.

PMID:
15213563
22.

Maternal toxicity and pregnancy complications in human immunodeficiency virus-infected women receiving antiretroviral therapy: PACTG 316.

Watts DH, Balasubramanian R, Maupin RT Jr, Delke I, Dorenbaum A, Fiore S, Newell ML, Delfraissy JF, Gelber RD, Mofenson LM, Culnane M, Cunningham CK; PACTG 316 Study Team.

Am J Obstet Gynecol. 2004 Feb;190(2):506-16.

PMID:
14981398
23.

Predose infant nevirapine concentration with the two-dose intrapartum neonatal nevirapine regimen: association with timing of maternal intrapartum nevirapine dose.

Mirochnick M, Dorenbaum A, Blanchard S, Cunningham CK, Gelber RD, Mofenson L, Culnane M, Sullivan JL.

J Acquir Immune Defic Syndr. 2003 Jun 1;33(2):153-6.

PMID:
12794547
24.

Tattoo pigment in lymph nodes mimicking metastatic malignant melanoma.

Friedman T, Westreich M, Mozes SN, Dorenbaum A, Herman O.

Plast Reconstr Surg. 2003 May;111(6):2120-2. No abstract available.

PMID:
12711995
25.

When the time comes to talk about HIV: factors associated with diagnostic disclosure and emotional distress in HIV-infected children.

Lester P, Chesney M, Cooke M, Weiss R, Whalley P, Perez B, Glidden D, Petru A, Dorenbaum A, Wara D.

J Acquir Immune Defic Syndr. 2002 Nov 1;31(3):309-17.

PMID:
12439206
26.

Concentrations of protease inhibitors in cord blood after in utero exposure.

Mirochnick M, Dorenbaum A, Holland D, Cunningham-Schrader B, Cunningham C, Gelber R, Mofenson L, Culnane M, Connor J, Sullivan JL.

Pediatr Infect Dis J. 2002 Sep;21(9):835-8.

PMID:
12352805
27.

Envelope-based HIV vaccines.

Donnelly JJ, Barnett SW, Dorenbaum A, Stamatatos L.

Science. 2002 Aug 23;297(5585):1277-8; author reply 1277-8. No abstract available.

PMID:
12194177
28.

Development of resistance mutations in women receiving standard antiretroviral therapy who received intrapartum nevirapine to prevent perinatal human immunodeficiency virus type 1 transmission: a substudy of pediatric AIDS clinical trials group protocol 316.

Cunningham CK, Chaix ML, Rekacewicz C, Britto P, Rouzioux C, Gelber RD, Dorenbaum A, Delfraissy JF, Bazin B, Mofenson L, Sullivan JL.

J Infect Dis. 2002 Jul 15;186(2):181-8. Epub 2002 Jun 26.

PMID:
12134253
29.

Two-dose intrapartum/newborn nevirapine and standard antiretroviral therapy to reduce perinatal HIV transmission: a randomized trial.

Dorenbaum A, Cunningham CK, Gelber RD, Culnane M, Mofenson L, Britto P, Rekacewicz C, Newell ML, Delfraissy JF, Cunningham-Schrader B, Mirochnick M, Sullivan JL; International PACTG 316 Team.

JAMA. 2002 Jul 10;288(2):189-98.

PMID:
12095383
30.

Two-stitch technique for distal shaft hypospadias repair.

Herman O, Heller L, Dorenbaum A, Westreich M.

Ann Plast Surg. 2002 Feb;48(2):209-12.

PMID:
11910231
31.

HIV medical advances explored at retrovirus conference.

Dorenbaum A, Miserez AR.

AIDS Policy Law. 2001 May 25;16(10):4. No abstract available.

PMID:
11569980
32.

When parents reject interventions to reduce postnatal human immunodeficiency virus transmission.

Wolf LE, Lo B, Beckerman KP, Dorenbaum A, Kilpatrick SJ, Weintrub PS.

Arch Pediatr Adolesc Med. 2001 Aug;155(8):927-33. Review.

PMID:
11483121
33.

Nevirapine: pharmacokinetic considerations in children and pregnant women.

Mirochnick M, Clarke DF, Dorenbaum A.

Clin Pharmacokinet. 2000 Oct;39(4):281-93. Review.

PMID:
11069214
34.

Cytokine profile of a long-term pediatric HIV survivor with hyper-IgE syndrome and a normal CD4 T-cell count.

Seroogy CM, Wara DW, Bluth MH, Dorenbaum A, White C, Durkin HG, Elder ME.

J Allergy Clin Immunol. 1999 Nov;104(5):1045-51.

PMID:
10550751
35.

Sleep disturbances in children with human immunodeficiency virus infection.

Franck LS, Johnson LM, Lee K, Hepner C, Lambert L, Passeri M, Manio E, Dorenbaum A, Wara D.

Pediatrics. 1999 Nov;104(5):e62.

PMID:
10545588
36.
37.

Phase I safety and pharmacokinetics study of micronized atovaquone in human immunodeficiency virus-infected infants and children. Pediatric AIDS Clinical Trials Group.

Hughes W, Dorenbaum A, Yogev R, Beauchamp B, Xu J, McNamara J, Moye J, Purdue L, van Dyke R, Rogers M, Sadler B.

Antimicrob Agents Chemother. 1998 Jun;42(6):1315-8.

38.

Transmission of HIV-1 in infants born to seropositive mothers: PCR-amplified proviral DNA detected by flow cytometric analysis of immunoreactive beads.

Dorenbaum A, Venkateswaran KS, Yang G, Comeau AM, Wara D, Vyas GN.

J Acquir Immune Defic Syndr Hum Retrovirol. 1997 May 1;15(1):35-42.

PMID:
9215652
39.

Recurrent Staphylococcus aureus renal abscess in a child positive for the human immunodeficiency virus.

Brandeis JM, Baskin LS, Kogan BA, Wara D, Dorenbaum A.

Urology. 1995 Aug;46(2):246-8.

PMID:
7624995
40.

Recovery of Malassezia pachydermatis from eight infants in a neonatal intensive care nursery: clinical and laboratory features.

Larocco M, Dorenbaum A, Robinson A, Pickering LK.

Pediatr Infect Dis J. 1988 Jun;7(6):398-401.

PMID:
3134645

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