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Immunological Comparison of Native and Recombinant Hen's Egg Yolk Allergen, Chicken Serum Albumin (Gal d 5), Produced in Kluveromyces lactis.

De Silva C, Dhanapala P, King S, Doran T, Tang M, Suphioglu C.

Nutrients. 2018 Jun 12;10(6). pii: E757. doi: 10.3390/nu10060757.


Incorporation of an Azobenzene β-Turn Peptidomimetic into Amyloid-β to Probe Potential Structural Motifs Leading to β-Sheet Self-Assembly.

Doran TM, Nilsson BL.

Methods Mol Biol. 2018;1777:387-406. doi: 10.1007/978-1-4939-7811-3_25.


Increasing socioeconomic gap between the young and old: temporal trends in health and overall deprivation in England by age, sex, urbanity and ethnicity, 2004-2015.

Kontopantelis E, Mamas MA, van Marwijk H, Buchan I, Ryan AM, Doran T.

J Epidemiol Community Health. 2018 Jul;72(7):636-644. doi: 10.1136/jech-2017-209895. Epub 2018 Mar 19.


Making and breaking a health service.

Doran T.

Health Econ Policy Law. 2018 Mar 16:1-6. doi: 10.1017/S1744133118000087. [Epub ahead of print]


Spatial distribution of clinical computer systems in primary care in England in 2016 and implications for primary care electronic medical record databases: a cross-sectional population study.

Kontopantelis E, Stevens RJ, Helms PJ, Edwards D, Doran T, Ashcroft DM.

BMJ Open. 2018 Feb 28;8(2):e020738. doi: 10.1136/bmjopen-2017-020738.


Innovative approaches to genome editing in avian species.

Cooper CA, Doran TJ, Challagulla A, Tizard MLV, Jenkins KA.

J Anim Sci Biotechnol. 2018 Feb 9;9:15. doi: 10.1186/s40104-018-0231-7. eCollection 2018. Review.


Regional variation and predictors of over-registration in English primary care in 2014: a spatial analysis.

Burch P, Doran T, Kontopantelis E.

J Epidemiol Community Health. 2018 Jun;72(6):532-538. doi: 10.1136/jech-2017-210176. Epub 2018 Feb 15.


Chronic morbidity, deprivation and primary medical care spending in England in 2015-16: a cross-sectional spatial analysis.

Kontopantelis E, Mamas MA, van Marwijk H, Ryan AM, Bower P, Guthrie B, Doran T.

BMC Med. 2018 Feb 14;16(1):19. doi: 10.1186/s12916-017-0996-0.


Health equity monitoring for healthcare quality assurance.

Cookson R, Asaria M, Ali S, Shaw R, Doran T, Goldblatt P.

Soc Sci Med. 2018 Feb;198:148-156. doi: 10.1016/j.socscimed.2018.01.004. Epub 2018 Jan 6.


Geographical epidemiology of health and overall deprivation in England, its changes and persistence from 2004 to 2015: a longitudinal spatial population study.

Kontopantelis E, Mamas MA, van Marwijk H, Ryan AM, Buchan IE, Ashcroft DM, Doran T.

J Epidemiol Community Health. 2018 Feb;72(2):140-147. doi: 10.1136/jech-2017-209999. Epub 2017 Dec 20.


Variations in mortality across the week following emergency admission to hospital: linked retrospective observational analyses of hospital episode data in England, 2004/5 to 2013/14.

Han L, Meacock R, Anselmi L, Kristensen SR, Sutton M, Doran T, Clough S, Power M.

Southampton (UK): NIHR Journals Library; 2017 Nov.


Impact of out-of-hours admission on patient mortality: longitudinal analysis in a tertiary acute hospital.

Han L, Sutton M, Clough S, Warner R, Doran T.

BMJ Qual Saf. 2018 Jun;27(6):445-454. doi: 10.1136/bmjqs-2017-006784. Epub 2017 Sep 29.


The role of the Quality and Outcomes Framework in the care of long-term conditions: a systematic review.

Forbes LJ, Marchand C, Doran T, Peckham S.

Br J Gen Pract. 2017 Nov;67(664):e775-e784. doi: 10.3399/bjgp17X693077. Epub 2017 Sep 25. Review.


Modulating Supramolecular Peptide Hydrogel Viscoelasticity Using Biomolecular Recognition.

DiMaio JTM, Doran TM, Ryan DM, Raymond DM, Nilsson BL.

Biomacromolecules. 2017 Nov 13;18(11):3591-3599. doi: 10.1021/acs.biomac.7b00925. Epub 2017 Sep 14.


Closing the mortality gap for severe mental illness: are we going in the right direction?

Siddiqi N, Doran T, Prady SL, Taylor J.

Br J Psychiatry. 2017 Sep;211(3):130-131. doi: 10.1192/bjp.bp.117.203026.


North-South disparities in English mortality1965-2015: longitudinal population study.

Buchan IE, Kontopantelis E, Sperrin M, Chandola T, Doran T.

J Epidemiol Community Health. 2017 Sep;71(9):928-936. doi: 10.1136/jech-2017-209195. Epub 2017 Aug 7. Erratum in: J Epidemiol Community Health. 2017 Oct 27;:.


Alcohol consumption and all-cause mortality: an analysis of general practice database records for patients with long-term conditions.

Stewart D, Han L, Doran T, McCambridge J.

J Epidemiol Community Health. 2017 Aug;71(8):729-735. doi: 10.1136/jech-2017-209241. Epub 2017 Jul 5.


Identifying primary care quality indicators for people with serious mental illness: a systematic review.

Kronenberg C, Doran T, Goddard M, Kendrick T, Gilbody S, Dare CR, Aylott L, Jacobs R.

Br J Gen Pract. 2017 Aug;67(661):e519-e530. doi: 10.3399/bjgp17X691721. Epub 2017 Jul 3. Review.


shRNAs targeting either the glycoprotein or polymerase genes inhibit Viral haemorrhagic septicaemia virus replication in zebrafish ZF4 cells.

Clarke BD, McColl KA, Ward AC, Doran TJ.

Antiviral Res. 2017 May;141:124-132. doi: 10.1016/j.antiviral.2017.02.012. Epub 2017 Feb 24.


Hypoallergenic Variant of the Major Egg White Allergen Gal d 1 Produced by Disruption of Cysteine Bridges.

Dhanapala P, Withanage-Dona D, Tang ML, Doran T, Suphioglu C.

Nutrients. 2017 Feb 21;9(2). pii: E171. doi: 10.3390/nu9020171.


Impact of Provider Incentives on Quality and Value of Health Care.

Doran T, Maurer KA, Ryan AM.

Annu Rev Public Health. 2017 Mar 20;38:449-465. doi: 10.1146/annurev-publhealth-032315-021457. Epub 2016 Dec 15. Review.


High-throughput Identification of DNA-Encoded IgG Ligands that Distinguish Active and Latent Mycobacterium tuberculosis Infections.

Mendes KR, Malone ML, Ndungu JM, Suponitsky-Kroyter I, Cavett VJ, McEnaney PJ, MacConnell AB, Doran TM, Ronacher K, Stanley K, Utset O, Walzl G, Paegel BM, Kodadek T.

ACS Chem Biol. 2017 Jan 20;12(1):234-243. doi: 10.1021/acschembio.6b00855. Epub 2016 Dec 13.


Generation of gene edited birds in one generation using sperm transfection assisted gene editing (STAGE).

Cooper CA, Challagulla A, Jenkins KA, Wise TG, O'Neil TE, Morris KR, Tizard ML, Doran TJ.

Transgenic Res. 2017 Jun;26(3):331-347. doi: 10.1007/s11248-016-0003-0. Epub 2016 Nov 28.


Arrival by ambulance explains variation in mortality by time of admission: retrospective study of admissions to hospital following emergency department attendance in England.

Anselmi L, Meacock R, Kristensen SR, Doran T, Sutton M.

BMJ Qual Saf. 2017 Aug;26(8):613-621. doi: 10.1136/bmjqs-2016-005680. Epub 2016 Oct 18.


Sodium channel-inhibiting drugs and cancer survival: protocol for a cohort study using the CPRD primary care database.

Fairhurst C, Martin F, Watt I, Doran T, Bland M, Brackenbury WJ.

BMJ Open. 2016 Sep 6;6(9):e011661. doi: 10.1136/bmjopen-2016-011661.


Higher mortality rates amongst emergency patients admitted to hospital at weekends reflect a lower probability of admission.

Meacock R, Anselmi L, Kristensen SR, Doran T, Sutton M.

J Health Serv Res Policy. 2017 Jan;22(1):12-19. doi: 10.1177/1355819616649630. Epub 2016 Jul 8.


Strategies to enable the adoption of animal biotechnology to sustainably improve global food safety and security.

Tizard M, Hallerman E, Fahrenkrug S, Newell-McGloughlin M, Gibson J, de Loos F, Wagner S, Laible G, Han JY, D'Occhio M, Kelly L, Lowenthal J, Gobius K, Silva P, Cooper C, Doran T.

Transgenic Res. 2016 Oct;25(5):575-95. doi: 10.1007/s11248-016-9965-1. Epub 2016 May 31. Review.


Long-term evidence for the effect of pay-for-performance in primary care on mortality in the UK: a population study.

Ryan AM, Krinsky S, Kontopantelis E, Doran T.

Lancet. 2016 Jul 16;388(10041):268-74. doi: 10.1016/S0140-6736(16)00276-2. Epub 2016 May 17.


The costs of inequality: whole-population modelling study of lifetime inpatient hospital costs in the English National Health Service by level of neighbourhood deprivation.

Asaria M, Doran T, Cookson R.

J Epidemiol Community Health. 2016 Oct;70(10):990-6. doi: 10.1136/jech-2016-207447. Epub 2016 May 17.


Discovery of Phosphorylated Peripherin as a Major Humoral Autoantigen in Type 1 Diabetes Mellitus.

Doran TM, Morimoto J, Simanski S, Koesema EJ, Clark LF, Pels K, Stoops SL, Pugliese A, Skyler JS, Kodadek T.

Cell Chem Biol. 2016 May 19;23(5):618-628. doi: 10.1016/j.chembiol.2016.04.006. Epub 2016 May 12.


Chemical Tools To Monitor and Manipulate Adaptive Immune Responses.

Doran TM, Sarkar M, Kodadek T.

J Am Chem Soc. 2016 May 18;138(19):6076-94. doi: 10.1021/jacs.6b02954. Epub 2016 May 3. Review.


Analysing indicators of performance, satisfaction, or safety using empirical logit transformation.

Stevens S, Valderas JM, Doran T, Perera R, Kontopantelis E.

BMJ. 2016 Mar 10;352:i1114. doi: 10.1136/bmj.i1114. No abstract available.


Modelling Conditions and Health Care Processes in Electronic Health Records: An Application to Severe Mental Illness with the Clinical Practice Research Datalink.

Olier I, Springate DA, Ashcroft DM, Doran T, Reeves D, Planner C, Reilly S, Kontopantelis E.

PLoS One. 2016 Feb 26;11(2):e0146715. doi: 10.1371/journal.pone.0146715. eCollection 2016.


Molecular and immunological analysis of hen's egg yolk allergens with a focus on YGP42 (Gal d 6).

De Silva C, Dhanapala P, Doran T, Tang MLK, Suphioglu C.

Mol Immunol. 2016 Mar;71:152-160. doi: 10.1016/j.molimm.2016.02.005. Epub 2016 Feb 18.


Advances in genetic engineering of the avian genome: "Realising the promise".

Doran TJ, Cooper CA, Jenkins KA, Tizard ML.

Transgenic Res. 2016 Jun;25(3):307-19. doi: 10.1007/s11248-016-9926-8. Epub 2016 Jan 28. Review.


Overexpression of Anti-Müllerian Hormone Disrupts Gonadal Sex Differentiation, Blocks Sex Hormone Synthesis, and Supports Cell Autonomous Sex Development in the Chicken.

Lambeth LS, Morris K, Ayers KL, Wise TG, O'Neil T, Wilson S, Cao Y, Sinclair AH, Cutting AD, Doran TJ, Smith CA.

Endocrinology. 2016 Mar;157(3):1258-75. doi: 10.1210/en.2015-1571. Epub 2016 Jan 25.


How a universal health system reduces inequalities: lessons from England.

Asaria M, Ali S, Doran T, Ferguson B, Fleetcroft R, Goddard M, Goldblatt P, Laudicella M, Raine R, Cookson R.

J Epidemiol Community Health. 2016 Jul;70(7):637-43. doi: 10.1136/jech-2015-206742. Epub 2016 Jan 19.


Primary care consultation rates among people with and without severe mental illness: a UK cohort study using the Clinical Practice Research Datalink.

Kontopantelis E, Olier I, Planner C, Reeves D, Ashcroft DM, Gask L, Doran T, Reilly S.

BMJ Open. 2015 Dec 16;5(12):e008650. doi: 10.1136/bmjopen-2015-008650.


Inequalities in physical comorbidity: a longitudinal comparative cohort study of people with severe mental illness in the UK.

Reilly S, Olier I, Planner C, Doran T, Reeves D, Ashcroft DM, Gask L, Kontopantelis E.

BMJ Open. 2015 Dec 15;5(12):e009010. doi: 10.1136/bmjopen-2015-009010.


Associations between exemption and survival outcomes in the UK's primary care pay-for-performance programme: a retrospective cohort study.

Kontopantelis E, Springate DA, Ashcroft DM, Valderas JM, van der Veer SN, Reeves D, Guthrie B, Doran T.

BMJ Qual Saf. 2016 Sep;25(9):657-70. doi: 10.1136/bmjqs-2015-004602. Epub 2015 Dec 1.


Transgenic Chickens Overexpressing Aromatase Have High Estrogen Levels but Maintain a Predominantly Male Phenotype.

Lambeth LS, Morris KR, Wise TG, Cummins DM, O'Neil TE, Cao Y, Sinclair AH, Doran TJ, Smith CA.

Endocrinology. 2016 Jan;157(1):83-90. doi: 10.1210/en.2015-1697. Epub 2015 Nov 10.


Impact of the Prevalence of Concordant and Discordant Conditions on the Quality of Diabetes Care in Family Practices in England.

Ricci-Cabello I, Stevens S, Kontopantelis E, Dalton AR, Griffiths RI, Campbell JL, Doran T, Valderas JM.

Ann Fam Med. 2015 Nov;13(6):514-22. doi: 10.1370/afm.1848.


Anti-Müllerian Hormone Is Required for Chicken Embryonic Urogenital System Growth but Not Sexual Differentiation.

Lambeth LS, Ayers K, Cutting AD, Doran TJ, Sinclair AH, Smith CA.

Biol Reprod. 2015 Dec;93(6):138. doi: 10.1095/biolreprod.115.131664. Epub 2015 Oct 28.


Reliable diagnosis of murine type 1 diabetes using a panel of autoantigens and "antigen surrogates" mounted onto a liquid array.

Doran TM, Morimoto J, Simanski S, McEnaney PJ, Kodadek T.

Mol Biosyst. 2015 Nov;11(11):3156-63. doi: 10.1039/c5mb00521c.


The death of death rates?

Doran T, Bloor K, Maynard A.

BMJ. 2015 Jul 14;351:h3466. doi: 10.1136/bmj.h3466. No abstract available.


High affinity binding of conformationally constrained synthetic oligomers to an antigen-specific antibody: Discovery of a diagnostically useful synthetic ligand for murine Type 1 diabetes autoantibodies.

Doran TM, Gao Y, Simanski S, McEnaney P, Kodadek T.

Bioorg Med Chem Lett. 2015 Nov 1;25(21):4910-4917. doi: 10.1016/j.bmcl.2015.05.046. Epub 2015 May 27.


Regression based quasi-experimental approach when randomisation is not an option: interrupted time series analysis.

Kontopantelis E, Doran T, Springate DA, Buchan I, Reeves D.

BMJ. 2015 Jun 9;350:h2750. doi: 10.1136/bmj.h2750. No abstract available.


Interlaboratory Validation for a Real-Time PCR Salmonella Detection Method Using the ABI 7500 FAST Real-Time PCR System.

Cheng CM, Doran T, Lin W, Chen KS, Williams-Hill D, Pamboukian R.

J Food Prot. 2015 Jun;78(6):1119-24. doi: 10.4315/0362-028X.JFP-14-244.


What are the Costs and Benefits of Providing Comprehensive Seven-day Services for Emergency Hospital Admissions?

Meacock R, Doran T, Sutton M.

Health Econ. 2015 Aug;24(8):907-12. doi: 10.1002/hec.3207. Epub 2015 May 22.


Does a local financial incentive scheme reduce inequalities in the delivery of clinical care in a socially deprived community? A longitudinal data analysis.

Glidewell L, West R, Hackett JE, Carder P, Doran T, Foy R.

BMC Fam Pract. 2015 May 14;16:61. doi: 10.1186/s12875-015-0279-9.

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