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Items: 1 to 50 of 189

1.

A randomised, multi-centre trial of total ankle replacement versus ankle arthrodesis in the treatment of patients with end stage ankle osteoarthritis (TARVA): statistical analysis plan.

Muller P, Skene SS, Chowdhury K, Cro S, Goldberg AJ, Doré CJ; TARVA Study Group.

Trials. 2020 Feb 18;21(1):197. doi: 10.1186/s13063-019-3973-4.

2.

Belimumab after B cell depletion therapy in patients with systemic lupus erythematosus (BEAT Lupus) protocol: a prospective multicentre, double-blind, randomised, placebo-controlled, 52-week phase II clinical trial.

Jones A, Muller P, Dore CJ, Ikeji F, Caverly E, Chowdhury K, Isenberg DA, Gordon C, Ehrenstein MR.

BMJ Open. 2019 Dec 16;9(12):e032569. doi: 10.1136/bmjopen-2019-032569.

3.

Minimally invasive autopsy for fetuses and children based on a combination of post-mortem MRI and endoscopic examination: a feasibility study.

Lewis C, Hutchinson JC, Riddington M, Hill M, Arthurs OJ, Fisher J, Wade A, Doré CJ, Chitty LS, Sebire NJ.

Health Technol Assess. 2019 Aug;23(46):1-104. doi: 10.3310/hta23460.

4.

Assessing feasibility of routine identification tools for mental health disorder in neurology clinics.

Bennett SD, Heyman I, Coughtrey AE, Buszewicz M, Byford S, Dore CJ, Fonagy P, Ford T, Moss-Morris R, Stephenson T, Varadkar S, Walker E, Shafran R.

Arch Dis Child. 2019 Dec;104(12):1161-1166. doi: 10.1136/archdischild-2018-316595. Epub 2019 May 11.

PMID:
31079075
5.

Neprilysin inhibition for pulmonary arterial hypertension: a randomized, double-blind, placebo-controlled, proof-of-concept trial.

Hobbs AJ, Moyes AJ, Baliga RS, Ghedia D, Ochiel R, Sylvestre Y, Doré CJ, Chowdhury K, Maclagan K, Quartly HL, Sofat R, Smit A, Schreiber BE, Coghlan GJ, MacAllister RJ.

Br J Pharmacol. 2019 May;176(9):1251-1267. doi: 10.1111/bph.14621. Epub 2019 Mar 31.

PMID:
30761523
6.
7.

Regulatory T cells as a biomarker for response to adalimumab in rheumatoid arthritis.

Nguyen DX, Cotton A, Attipoe L, Ciurtin C, Doré CJ, Ehrenstein MR.

J Allergy Clin Immunol. 2018 Sep;142(3):978-980.e9. doi: 10.1016/j.jaci.2018.04.026. Epub 2018 Jun 20. No abstract available.

8.

Optimizing treatment with tumour necrosis factor inhibitors in rheumatoid arthritis-a proof of principle and exploratory trial: is dose tapering practical in good responders?

Ibrahim F, Lorente-Cánovas B, Doré CJ, Bosworth A, Ma MH, Galloway JB, Cope AP, Pande I, Walker D, Scott DL.

Rheumatology (Oxford). 2017 Nov 1;56(11):2004-2014. doi: 10.1093/rheumatology/kex315.

9.

Ophthalmic statistics note 12: multivariable or multivariate: what's in a name?

Bunce C, Czanner G, Grzeda MT, Doré CJ, Freemantle N.

Br J Ophthalmol. 2017 Oct;101(10):1303-1305. doi: 10.1136/bjophthalmol-2017-310846. Epub 2017 Aug 16. No abstract available.

10.

Ophthalmic statistics note 11: logistic regression.

Stephenson J, Bunce C, Doré CJ, Freemantle N; Ophthalmic Statistics Group.

Br J Ophthalmol. 2016 Dec;100(12):1594-1595. doi: 10.1136/bjophthalmol-2016-309223. Epub 2016 Nov 3. No abstract available.

11.

The effect of vitamin D supplementation on knee osteoarthritis, the VIDEO study: a randomised controlled trial.

Arden NK, Cro S, Sheard S, Doré CJ, Bara A, Tebbs SA, Hunter DJ, James S, Cooper C, O'Neill TW, Macgregor A, Birrell F, Keen R.

Osteoarthritis Cartilage. 2016 Nov;24(11):1858-1866. doi: 10.1016/j.joca.2016.05.020. Epub 2016 Jun 2.

12.

Total ankle replacement versus arthrodesis (TARVA): protocol for a multicentre randomised controlled trial.

Goldberg AJ, Zaidi R, Thomson C, Doré CJ, Skene SS, Cro S, Round J, Molloy A, Davies M, Karski M, Kim L, Cooke P; TARVA study group.

BMJ Open. 2016 Sep 6;6(9):e012716. doi: 10.1136/bmjopen-2016-012716.

13.

Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised, controlled, open-label, phase 2/3, non-inferiority trial.

Cohen H, Hunt BJ, Efthymiou M, Arachchillage DR, Mackie IJ, Clawson S, Sylvestre Y, Machin SJ, Bertolaccini ML, Ruiz-Castellano M, Muirhead N, Doré CJ, Khamashta M, Isenberg DA; RAPS trial investigators.

Lancet Haematol. 2016 Sep;3(9):e426-36. doi: 10.1016/S2352-3026(16)30079-5.

14.

SPIRIT 2013 Statement: defining standard protocol items for clinical trials.

Chan AW, Tetzlaff JM, Altman DG, Laupacis A, Gøtzsche PC, Krle A-Jerić K, Hrobjartsson A, Mann H, Dickersin K, Berlin JA, Dore CJ, Parulekar WR, Summerskill WS, Groves T, Schulz KF, Sox HC, Rockhold FW, Rennie D, Moher D.

Rev Panam Salud Publica. 2015 Dec;38(6):506-14.

15.

Ophthalmic statistics note 10: data transformations.

Bunce C, Stephenson J, Doré CJ, Freemantle N; Ophthalmic Statistics Group.

Br J Ophthalmol. 2016 Dec;100(12):1591-1593. doi: 10.1136/bjophthalmol-2016-308824. Epub 2016 Jul 18. No abstract available.

PMID:
27432738
16.

Results of a prepilot study of potential test material for the external quality assessment of reticulocyte haemoglobin content.

Hinchliffe RF, Mahon A, Thomas W, Doré CJ, Briggs C, De la Salle B, Hyde K.

Int J Lab Hematol. 2016 Aug;38(4):e86-8. doi: 10.1111/ijlh.12514. Epub 2016 Jun 16. No abstract available.

PMID:
27307309
17.

SWIM (sickle with ibuprofen and morphine) randomised controlled trial fails to recruit: lessons learnt.

Cho G, Anie KA, Buckton J, Kiilu P, Layton M, Alexander L, Hemmaway C, Sutton D, Amos C, Doré CJ, Kahan B, Meredith S.

BMJ Open. 2016 Jun 9;6(6):e011276. doi: 10.1136/bmjopen-2016-011276.

18.

Bias was reduced in an open-label trial through the removal of subjective elements from the outcome definition.

Kahan BC, Doré CJ, Murphy MF, Jairath V.

J Clin Epidemiol. 2016 Sep;77:38-43. doi: 10.1016/j.jclinepi.2016.05.008. Epub 2016 Jun 1.

PMID:
27262238
19.

Ophthalmic statistics note 9: parametric versus non-parametric methods for data analysis.

Skene SS, Bunce C, Freemantle N, Doré CJ; Ophthalmic Statistics Group.

Br J Ophthalmol. 2016 Jul;100(7):877-878. doi: 10.1136/bjophthalmol-2015-308252. Epub 2016 Apr 27. No abstract available.

20.

Nutritional Evaluation and Optimisation in Neonates: a randomized, double-blind controlled trial of amino acid regimen and intravenous lipid composition in preterm parenteral nutrition.

Uthaya S, Liu X, Babalis D, Doré CJ, Warwick J, Bell J, Thomas L, Ashby D, Durighel G, Ederies A, Yanez-Lopez M, Modi N.

Am J Clin Nutr. 2016 Jun;103(6):1443-52. doi: 10.3945/ajcn.115.125138. Epub 2016 Apr 20.

21.

Ophthalmic statistics note 8: missing data--exploring the unknown.

Bunce C, Quartilho A, Freemantle N, Doré CJ; Ophthalmic Statistics Group.

Br J Ophthalmol. 2016 Mar;100(3):291-4. doi: 10.1136/bjophthalmol-2015-307821. Epub 2015 Dec 30. No abstract available.

22.

Randomised, single-masked non-inferiority trial of femtosecond laser-assisted versus manual phacoemulsification cataract surgery for adults with visually significant cataract: the FACT trial protocol.

Day AC, Burr JM, Bunce C, Doré CJ, Sylvestre Y, Wormald RP, Round J, McCudden V, Rubin G, Wilkins MR; FACT Group.

BMJ Open. 2015 Nov 27;5(11):e010381. doi: 10.1136/bmjopen-2015-010381.

23.

A re-randomisation design for clinical trials.

Kahan BC, Forbes AB, Doré CJ, Morris TP.

BMC Med Res Methodol. 2015 Nov 5;15:96. doi: 10.1186/s12874-015-0082-2.

24.

A randomised controlled trial of flow driver and bubble continuous positive airway pressure in preterm infants in a resource-limited setting.

Mazmanyan P, Mellor K, Doré CJ, Modi N.

Arch Dis Child Fetal Neonatal Ed. 2016 Jan;101(1):F16-20. doi: 10.1136/archdischild-2015-308464. Epub 2015 Aug 13.

PMID:
26271753
25.

Quantitative Maximum Shear-Wave Stiffness of Breast Masses as a Predictor of Histopathologic Severity.

Berg WA, Mendelson EB, Cosgrove DO, Doré CJ, Gay J, Henry JP, Cohen-Bacrie C.

AJR Am J Roentgenol. 2015 Aug;205(2):448-55. doi: 10.2214/AJR.14.13448.

PMID:
26204299
26.

Ophthalmic statistics note 7: multiple hypothesis testing—to adjust or not to adjust.

Cipriani V, Quartilho A, Bunce C, Freemantle N, Doré CJ; Ophthalmic Statistics Group.

Br J Ophthalmol. 2015 Sep;99(9):1155-7. doi: 10.1136/bjophthalmol-2015-306784. Epub 2015 Jun 25. No abstract available.

27.

Restrictive versus liberal blood transfusion for acute upper gastrointestinal bleeding (TRIGGER): a pragmatic, open-label, cluster randomised feasibility trial.

Jairath V, Kahan BC, Gray A, Doré CJ, Mora A, James MW, Stanley AJ, Everett SM, Bailey AA, Dallal H, Greenaway J, Le Jeune I, Darwent M, Church N, Reckless I, Hodge R, Dyer C, Meredith S, Llewelyn C, Palmer KR, Logan RF, Travis SP, Walsh TS, Murphy MF.

Lancet. 2015 Jul 11;386(9989):137-44. doi: 10.1016/S0140-6736(14)61999-1. Epub 2015 May 5.

PMID:
25956718
28.

Rivaroxaban in antiphospholipid syndrome (RAPS) protocol: a prospective, randomized controlled phase II/III clinical trial of rivaroxaban versus warfarin in patients with thrombotic antiphospholipid syndrome, with or without SLE.

Cohen H, Doré CJ, Clawson S, Hunt BJ, Isenberg D, Khamashta M, Muirhead N; RAPS Trial Protocol Collaborators.

Lupus. 2015 Sep;24(10):1087-94. doi: 10.1177/0961203315581207. Epub 2015 May 4.

29.

A randomised trial of granulocyte-macrophage colony-stimulating factor for neonatal sepsis: childhood outcomes at 5 years.

Marlow N, Morris T, Brocklehurst P, Carr R, Cowan F, Patel N, Petrou S, Redshaw M, Modi N, Doré CJ.

Arch Dis Child Fetal Neonatal Ed. 2015 Jul;100(4):F320-6. doi: 10.1136/archdischild-2014-307410. Epub 2015 Apr 28.

30.

Ophthalmic statistics note 6: effect sizes matter.

Cook JA, Bunce C, Doré CJ, Freemantle N; Ophthalmic Statistics Group.

Br J Ophthalmol. 2015 May;99(5):580-1. doi: 10.1136/bjophthalmol-2014-306303. Epub 2015 Feb 26. No abstract available.

31.

Ophthalmic statistics note 5: diagnostic tests—sensitivity and specificity.

Saunders LJ, Zhu H, Bunce C, Doré CJ, Freemantle N, Crabb DP; Ophthalmic Statistics Group.

Br J Ophthalmol. 2015 Sep;99(9):1168-70. doi: 10.1136/bjophthalmol-2014-306055. Epub 2014 Dec 8. Review.

32.

Second-line agents in myositis: 1-year factorial trial of additional immunosuppression in patients who have partially responded to steroids.

Ibrahim F, Choy E, Gordon P, Doré CJ, Hakim A, Kitas G, Isenberg D, Griffiths B, Lecky B, Chakravarty K, Winer J, Danko K, Cooper RG, White-Alao B, Scott DL.

Rheumatology (Oxford). 2015 Jun;54(6):1050-5. doi: 10.1093/rheumatology/keu442. Epub 2014 Nov 27.

33.

Reducing bias in open-label trials where blinded outcome assessment is not feasible: strategies from two randomised trials.

Kahan BC, Cro S, Doré CJ, Bratton DJ, Rehal S, Maskell NA, Rahman N, Jairath V.

Trials. 2014 Nov 21;15:456. doi: 10.1186/1745-6215-15-456.

34.

Ophthalmic Statistics Note 4: analysing data from randomised controlled trials with baseline and follow-up measurements.

Nash R, Bunce C, Freemantle N, Doré CJ, Rogers CA; Ophthalmic Statistics Group.

Br J Ophthalmol. 2014 Nov;98(11):1467-9. doi: 10.1136/bjophthalmol-2014-305614. Epub 2014 Aug 7. No abstract available.

35.

The risks and rewards of covariate adjustment in randomized trials: an assessment of 12 outcomes from 8 studies.

Kahan BC, Jairath V, Doré CJ, Morris TP.

Trials. 2014 Apr 23;15:139. doi: 10.1186/1745-6215-15-139.

36.

Rehabilitation following surgery for lumbar spinal stenosis. A Cochrane review.

McGregor AH, Probyn K, Cro S, Doré CJ, Burton AK, Balagué F, Pincus T, Fairbank J.

Spine (Phila Pa 1976). 2014 Jun 1;39(13):1044-54. doi: 10.1097/BRS.0000000000000355. Review.

PMID:
24732858
37.

Ophthalmic statistics note: the perils of dichotomising continuous variables.

Cumberland PM, Czanner G, Bunce C, Doré CJ, Freemantle N, García-Fiñana M; Ophthalmic Statistics Group.

Br J Ophthalmol. 2014 Jun;98(6):841-3. doi: 10.1136/bjophthalmol-2014-304930. Epub 2014 Mar 28. No abstract available.

38.

Ophthalmic statistics note 2: absence of evidence is not evidence of absence.

Bunce C, Patel KV, Xing W, Freemantle N, Doré CJ; Ophthalmic Statistics Group.

Br J Ophthalmol. 2014 May;98(5):703-5. doi: 10.1136/bjophthalmol-2013-304811. Epub 2014 Mar 3. No abstract available.

39.

Quantifying missing annual emission sources of heavy metals in the United Kingdom with an atmospheric transport model.

Dore AJ, Hallsworth S, McDonald AG, Werner M, Kryza M, Abbot J, Nemitz E, Dore CJ, Malcolm H, Vieno M, Reis S, Fowler D.

Sci Total Environ. 2014 May 1;479-480:171-80. doi: 10.1016/j.scitotenv.2014.02.001. Epub 2014 Feb 20.

40.

Three-year outcomes of cultured limbal epithelial allografts in aniridia and Stevens-Johnson syndrome evaluated using the Clinical Outcome Assessment in Surgical Trials assessment tool.

Shortt AJ, Bunce C, Levis HJ, Blows P, Doré CJ, Vernon A, Secker GA, Tuft SJ, Daniels JT.

Stem Cells Transl Med. 2014 Feb;3(2):265-75. doi: 10.5966/sctm.2013-0025. Epub 2014 Jan 17.

41.

Ophthalmic statistics note 1: unit of analysis.

Bunce C, Patel KV, Xing W, Freemantle N, Doré CJ; Ophthalmic Statistics Group.

Br J Ophthalmol. 2014 Mar;98(3):408-12. doi: 10.1136/bjophthalmol-2013-304587. Epub 2013 Dec 19. No abstract available.

42.

Rehabilitation following surgery for lumbar spinal stenosis.

McGregor AH, Probyn K, Cro S, Doré CJ, Burton AK, Balagué F, Pincus T, Fairbank J.

Cochrane Database Syst Rev. 2013 Dec 9;(12):CD009644. doi: 10.1002/14651858.CD009644.pub2. Review.

PMID:
24323844
43.

An exploration of patients' expectation of and satisfaction with surgical outcome.

McGregor AH, Doré CJ, Morris TP.

Eur Spine J. 2013 Dec;22(12):2836-44. doi: 10.1007/s00586-013-2971-6. Epub 2013 Aug 30.

44.
45.

Restrictive vs liberal blood transfusion for acute upper gastrointestinal bleeding: rationale and protocol for a cluster randomized feasibility trial.

Jairath V, Kahan BC, Gray A, Doré CJ, Mora A, Dyer C, Stokes EA, Llewelyn C, Bailey AA, Dallal H, Everett SM, James MW, Stanley AJ, Church N, Darwent M, Greenaway J, Le Jeune I, Reckless I, Campbell HE, Meredith S, Palmer KR, Logan RF, Travis SP, Walsh TS, Murphy MF.

Transfus Med Rev. 2013 Jul;27(3):146-53. doi: 10.1016/j.tmrv.2013.04.001. Epub 2013 May 22.

46.

SPIRIT 2013 statement: defining standard protocol items for clinical trials.

Chan AW, Tetzlaff JM, Altman DG, Laupacis A, Gøtzsche PC, Krleža-Jerić K, Hróbjartsson A, Mann H, Dickersin K, Berlin JA, Doré CJ, Parulekar WR, Summerskill WS, Groves T, Schulz KF, Sox HC, Rockhold FW, Rennie D, Moher D.

Ann Intern Med. 2013 Feb 5;158(3):200-7. doi: 10.7326/0003-4819-158-3-201302050-00583.

47.

Spectral-domain optical coherence tomography in subjects over 60 years of age, and its implications for designing clinical trials.

Comyn O, Bunce C, Patel PJ, Doré CJ.

Br J Ophthalmol. 2013 Apr;97(4):533. doi: 10.1136/bjophthalmol-2012-302923. Epub 2012 Dec 25. No abstract available.

PMID:
23269678
48.

Color Doppler ultrasonography of lumbar artery blood flow in patients with low back pain.

Espahbodi S, Doré CJ, Humphries KN, Hughes SP.

Spine (Phila Pa 1976). 2013 Feb 15;38(4):E230-6. doi: 10.1097/BRS.0b013e31827ecd6e.

PMID:
23197013
49.

National audit of the use of surgery and radiological embolization after failed endoscopic haemostasis for non-variceal upper gastrointestinal bleeding.

Jairath V, Kahan BC, Logan RF, Hearnshaw SA, Dore CJ, Travis SP, Murphy MF, Palmer KR.

Br J Surg. 2012 Dec;99(12):1672-80. doi: 10.1002/bjs.8932. Epub 2012 Sep 28.

PMID:
23023268
50.

A randomized, double-blind, placebo-controlled trial of low-dose oral prednisolone for treating painful hand osteoarthritis.

Wenham CY, Hensor EM, Grainger AJ, Hodgson R, Balamoody S, Doré CJ, Emery P, Conaghan PG.

Rheumatology (Oxford). 2012 Dec;51(12):2286-94. doi: 10.1093/rheumatology/kes219. Epub 2012 Sep 6.

PMID:
22956551

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