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Items: 1 to 50 of 103

1.

Human papillomavirus type 16 causes a defined subset of conjunctival in situ squamous cell carcinomas.

Griffin H, Singh Mudhar H, Rundle P, Shiraz A, Mahmood R, Egawa N, Quint W, Rennie IG, Doorbar J.

Mod Pathol. 2019 Sep 4. doi: 10.1038/s41379-019-0350-5. [Epub ahead of print]

PMID:
31485010
2.

Grading immunohistochemical markers p16INK4a and HPV E4 identifies productive and transforming lesions caused by low- and high-risk HPV within high-grade anal squamous intraepithelial lesions.

Leeman A, Jenkins D, Marra E, van Zummeren M, Pirog EC, van de Sandt MM, van Eeden A, Schim van der Loeff MF, Doorbar J, de Vries HJC, van Kemenade FJ, Meijer CJLM, Quint WGV.

Br J Dermatol. 2019 Jul 14. doi: 10.1111/bjd.18342. [Epub ahead of print]

PMID:
31302935
3.

Roles for E1-independent replication and E6-mediated p53 degradation during low-risk and high-risk human papillomavirus genome maintenance.

Murakami I, Egawa N, Griffin H, Yin W, Kranjec C, Nakahara T, Kiyono T, Doorbar J.

PLoS Pathog. 2019 May 13;15(5):e1007755. doi: 10.1371/journal.ppat.1007755. eCollection 2019 May.

4.

Refining our understanding of cervical neoplasia and its cellular origins.

Doorbar J, Griffin H.

Papillomavirus Res. 2019 Jun;7:176-179. doi: 10.1016/j.pvr.2019.04.005. Epub 2019 Apr 8. Review.

5.

Whole tissue cervical mapping of HPV infection: Molecular evidence for focal latent HPV infection in humans.

Hammer A, de Koning MN, Blaakaer J, Steiniche T, Doorbar J, Griffin H, Mejlgaard E, Svanholm H, Quint WG, Gravitt PE.

Papillomavirus Res. 2019 Jun;7:82-87. doi: 10.1016/j.pvr.2019.02.004. Epub 2019 Feb 14.

6.

Risk stratification of cervical disease using detection of human papillomavirus (HPV) E4 protein and cellular MCM protein in clinical liquid based cytology samples.

Stevenson A, Kavanagh K, Pan J, Stevenson L, Griffin H, Doorbar J, Scott E, Deeny M, Cuschieri K, Graham SV.

J Clin Virol. 2018 Nov;108:19-25. doi: 10.1016/j.jcv.2018.08.011. Epub 2018 Aug 31.

7.

The Role of Human Papillomaviruses and Polyomaviruses in BRAF-Inhibitor Induced Cutaneous Squamous Cell Carcinoma and Benign Squamoproliferative Lesions.

Purdie KJ, Proby CM, Rizvi H, Griffin H, Doorbar J, Sommerlad M, Feltkamp MC, der Meijden EV, Inman GJ, South AP, Leigh IM, Harwood CA.

Front Microbiol. 2018 Aug 14;9:1806. doi: 10.3389/fmicb.2018.01806. eCollection 2018.

8.

HPV E4 expression and DNA hypermethylation of CADM1, MAL, and miR124-2 genes in cervical cancer and precursor lesions.

Zummeren MV, Kremer WW, Leeman A, Bleeker MCG, Jenkins D, Sandt MV, Doorbar J, Heideman DAM, Steenbergen RDM, Snijders PJF, Kenter GG, Quint WGV, Berkhof J, Meijer CJLM.

Mod Pathol. 2018 Dec;31(12):1842-1850. doi: 10.1038/s41379-018-0101-z. Epub 2018 Aug 22.

PMID:
30135508
9.

Presence or Absence of Significant HPVE4 Expression in High-grade Anal Intraepithelial Neoplasia With p16/Ki-67 Positivity Indicates Distinct Patterns of Neoplasia: A Study Combining Immunohistochemistry and Laser Capture Microdissection PCR.

Leeman A, Pirog EC, Doorbar J, van de Sandt MM, van Kemenade FJ, Jenkins D, Quint WGV.

Am J Surg Pathol. 2018 Apr;42(4):463-471. doi: 10.1097/PAS.0000000000000984.

PMID:
29438174
10.

Mutations in HPV18 E1^E4 Impact Virus Capsid Assembly, Infectivity Competence, and Maturation.

Biryukov J, Myers JC, McLaughlin-Drubin ME, Griffin HM, Milici J, Doorbar J, Meyers C.

Viruses. 2017 Dec 19;9(12). pii: E385. doi: 10.3390/v9120385.

11.

The high-risk HPV E6 target scribble (hScrib) is required for HPV E6 expression in cervical tumour-derived cell lines.

Kranjec C, Tomaić V, Massimi P, Nicolaides L, Doorbar J, Banks L.

Papillomavirus Res. 2016 Dec;2:70-77. doi: 10.1016/j.pvr.2016.04.001. Epub 2016 Apr 7.

12.

p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells.

Periyasamy M, Singh AK, Gemma C, Kranjec C, Farzan R, Leach DA, Navaratnam N, Pálinkás HL, Vértessy BG, Fenton TR, Doorbar J, Fuller-Pace F, Meek DW, Coombes RC, Buluwela L, Ali S.

Nucleic Acids Res. 2017 Nov 2;45(19):11056-11069. doi: 10.1093/nar/gkx721.

13.

HPV8-E6 Interferes with Syntenin-2 Expression through Deregulation of Differentiation, Methylation and Phosphatidylinositide-Kinase Dependent Mechanisms.

Marx B, Miller-Lazic D, Doorbar J, Majewski S, Hofmann K, Hufbauer M, Akgül B.

Front Microbiol. 2017 Sep 8;8:1724. doi: 10.3389/fmicb.2017.01724. eCollection 2017.

14.

Host control of human papillomavirus infection and disease.

Doorbar J.

Best Pract Res Clin Obstet Gynaecol. 2018 Feb;47:27-41. doi: 10.1016/j.bpobgyn.2017.08.001. Epub 2017 Aug 12. Review.

PMID:
28919159
15.

Modulation of basal cell fate during productive and transforming HPV-16 infection is mediated by progressive E6-driven depletion of Notch.

Kranjec C, Holleywood C, Libert D, Griffin H, Mahmood R, Isaacson E, Doorbar J.

J Pathol. 2017 Aug;242(4):448-462. doi: 10.1002/path.4917.

16.

HPV16 and 18 genome amplification show different E4-dependence, with 16E4 enhancing E1 nuclear accumulation and replicative efficiency via its cell cycle arrest and kinase activation functions.

Egawa N, Wang Q, Griffin HM, Murakami I, Jackson D, Mahmood R, Doorbar J.

PLoS Pathog. 2017 Mar 17;13(3):e1006282. doi: 10.1371/journal.ppat.1006282. eCollection 2017 Mar.

17.

The low-risk papillomaviruses.

Egawa N, Doorbar J.

Virus Res. 2017 Mar 2;231:119-127. doi: 10.1016/j.virusres.2016.12.017. Epub 2016 Dec 28. Review.

18.

The CXCL12/CXCR4 Signaling Pathway: A New Susceptibility Factor in Human Papillomavirus Pathogenesis.

Meuris F, Carthagena L, Jaracz-Ros A, Gaudin F, Cutolo P, Deback C, Xue Y, Thierry F, Doorbar J, Bachelerie F.

PLoS Pathog. 2016 Dec 5;12(12):e1006039. doi: 10.1371/journal.ppat.1006039. eCollection 2016 Dec.

19.

Carcinogenic human papillomavirus infection.

Schiffman M, Doorbar J, Wentzensen N, de Sanjosé S, Fakhry C, Monk BJ, Stanley MA, Franceschi S.

Nat Rev Dis Primers. 2016 Dec 1;2:16086. doi: 10.1038/nrdp.2016.86. Review.

PMID:
27905473
20.

Interaction of the Human Papillomavirus E6 Oncoprotein with Sorting Nexin 27 Modulates Endocytic Cargo Transport Pathways.

Ganti K, Massimi P, Manzo-Merino J, Tomaić V, Pim D, Playford MP, Lizano M, Roberts S, Kranjec C, Doorbar J, Banks L.

PLoS Pathog. 2016 Sep 20;12(9):e1005854. doi: 10.1371/journal.ppat.1005854. eCollection 2016 Sep.

21.

Human papillomavirus infection and induction of neoplasia: a matter of fitness.

Kranjec C, Doorbar J.

Curr Opin Virol. 2016 Oct;20:129-136. doi: 10.1016/j.coviro.2016.08.011. Epub 2016 Sep 3. Review.

PMID:
27600900
23.

Detection of Papillomavirus Gene Expression Patterns in Tissue Sections.

Griffin H, Doorbar J.

Curr Protoc Microbiol. 2016 May 6;41:14B.7.1-14B.7.20. doi: 10.1002/cpmc.6.

PMID:
27153382
24.

Model systems of human papillomavirus-associated disease.

Doorbar J.

J Pathol. 2016 Jan;238(2):166-79. doi: 10.1002/path.4656. Epub 2015 Dec 10. Review.

PMID:
26456009
25.

Investigating Diagnostic Problems of CIN1 and CIN2 Associated With High-risk HPV by Combining the Novel Molecular Biomarker PanHPVE4 With P16INK4a.

van Baars R, Griffin H, Wu Z, Soneji YJ, van de Sandt M, Arora R, van der Marel J, Ter Harmsel B, Jach R, Okon K, Huras H, Jenkins D, Quint W, Doorbar J.

Am J Surg Pathol. 2015 Nov;39(11):1518-1528. doi: 10.1097/PAS.0000000000000498.

26.

Presence of human papillomavirus in semen of healthy men is firmly associated with HPV infections of the penile epithelium.

Luttmer R, Dijkstra MG, Snijders PJF, Jordanova ES, King AJ, Pronk DTM, Foresta C, Garolla A, Hompes PGA, Berkhof J, Bleeker MCG, Doorbar J, Heideman DAM, Meijer CJLM.

Fertil Steril. 2015 Oct;104(4):838-844.e8. doi: 10.1016/j.fertnstert.2015.06.028. Epub 2015 Jul 23.

PMID:
26211884
27.

Human Papillomaviruses; Epithelial Tropisms, and the Development of Neoplasia.

Egawa N, Egawa K, Griffin H, Doorbar J.

Viruses. 2015 Jul 16;7(7):3863-90. doi: 10.3390/v7072802. Review.

28.

Stratification of HPV-induced cervical pathology using the virally encoded molecular marker E4 in combination with p16 or MCM.

Griffin H, Soneji Y, Van Baars R, Arora R, Jenkins D, van de Sandt M, Wu Z, Quint W, Jach R, Okon K, Huras H, Singer A, Doorbar J.

Mod Pathol. 2015 Jul;28(7):977-93. doi: 10.1038/modpathol.2015.52. Epub 2015 May 8.

29.

Human papillomavirus molecular biology and disease association.

Doorbar J, Egawa N, Griffin H, Kranjec C, Murakami I.

Rev Med Virol. 2015 Mar;25 Suppl 1:2-23. doi: 10.1002/rmv.1822. Review.

30.

Identification of the skin virome in a boy with widespread human papillomavirus-2-positive warts that completely regressed after administration of tetravalent human papillomavirus vaccine.

Landini MM, Borgogna C, Peretti A, Doorbar J, Griffin H, Mignone F, Lai A, Urbinati L, Matteelli A, Gariglio M, De Andrea M.

Br J Dermatol. 2015 Aug;173(2):597-600. doi: 10.1111/bjd.13707. Epub 2015 Jun 25. No abstract available.

31.

Human Beta-papillomavirus infection and keratinocyte carcinomas.

Quint KD, Genders RE, de Koning MN, Borgogna C, Gariglio M, Bouwes Bavinck JN, Doorbar J, Feltkamp MC.

J Pathol. 2015 Jan;235(2):342-54. doi: 10.1002/path.4425. Review.

PMID:
25131163
32.

Characterization of skin lesions induced by skin-tropic α- and β-papillomaviruses in a patient with epidermodysplasia verruciformis.

Borgogna C, Landini MM, Lanfredini S, Doorbar J, Bouwes Bavinck JN, Quint KD, de Koning MN, Genders RE, Gariglio M.

Br J Dermatol. 2014 Dec;171(6):1550-4. doi: 10.1111/bjd.13156. Epub 2014 Nov 30.

PMID:
24902472
33.

α- and β-papillomavirus infection in a young patient with an unclassified primary T-cell immunodeficiency and multiple mucosal and cutaneous lesions.

Landini MM, Borgogna C, Peretti A, Colombo E, Zavattaro E, Boldorini R, Miglio U, Doorbar J, Ravanini P, Kumar R, Moratto D, Badolato R, De Andrea M, Gariglio M.

J Am Acad Dermatol. 2014 Jul;71(1):108-15.e1. doi: 10.1016/j.jaad.2014.01.859. Epub 2014 Mar 4.

34.

Improved detection reveals active β-papillomavirus infection in skin lesions from kidney transplant recipients.

Borgogna C, Lanfredini S, Peretti A, De Andrea M, Zavattaro E, Colombo E, Quaglia M, Boldorini R, Miglio U, Doorbar J, Bavinck JN, Quint KD, de Koning MN, Landolfo S, Gariglio M.

Mod Pathol. 2014 Aug;27(8):1101-15. doi: 10.1038/modpathol.2013.240. Epub 2014 Jan 3. Erratum in: Mod Pathol. 2014 Jun;27(6):917.

35.

Comprehensive control of human papillomavirus infections and related diseases.

Bosch FX, Broker TR, Forman D, Moscicki AB, Gillison ML, Doorbar J, Stern PL, Stanley M, Arbyn M, Poljak M, Cuzick J, Castle PE, Schiller JT, Markowitz LE, Fisher WA, Canfell K, Denny LA, Franco EL, Steben M, Kane MA, Schiffman M, Meijer CJ, Sankaranarayanan R, Castellsagué X, Kim JJ, Brotons M, Alemany L, Albero G, Diaz M, de Sanjosé S; authors of ICO Monograph Comprehensive Control of HPV Infections and Related Diseases Vaccine Volume 30, Supplement 5, 2012.

Vaccine. 2013 Dec 31;31 Suppl 7:H1-31. doi: 10.1016/j.vaccine.2013.10.003.

PMID:
24332295
36.

Comprehensive control of human papillomavirus infections and related diseases.

Bosch FX, Broker TR, Forman D, Moscicki AB, Gillison ML, Doorbar J, Stern PL, Stanley M, Arbyn M, Poljak M, Cuzick J, Castle PE, Schiller JT, Markowitz LE, Fisher WA, Canfell K, Denny LA, Franco EL, Steben M, Kane MA, Schiffman M, Meijer CJ, Sankaranarayanan R, Castellsagué X, Kim JJ, Brotons M, Alemany L, Albero G, Diaz M, de Sanjosé S; ICO Monograph 'Comprehensive Control of HPV Infections and Related Diseases' Vaccine Volume 30, Supplement 5, 2012.

Vaccine. 2013 Dec 30;31 Suppl 6:G1-31. doi: 10.1016/j.vaccine.2013.10.002. Review.

PMID:
24331817
37.

Comprehensive control of human papillomavirus infections and related diseases.

Bosch FX, Broker TR, Forman D, Moscicki AB, Gillison ML, Doorbar J, Stern PL, Stanley M, Arbyn M, Poljak M, Cuzick J, Castle PE, Schiller JT, Markowitz LE, Fisher WA, Canfell K, Denny LA, Franco EL, Steben M, Kane MA, Schiffman M, Meijer CJ, Sankaranarayanan R, Castellsagué X, Kim JJ, Brotons M, Alemany L, Albero G, Diaz M, de Sanjosé S; authors of the ICO Monograph ‘Comprehensive Control of HPV Infections and Related Diseases’ Vaccine Volume 30, Supplement 5, 2012.

Vaccine. 2013 Dec 29;31 Suppl 5:F1-31. doi: 10.1016/j.vaccine.2013.10.001. Review.

PMID:
24331745
38.

Comprehensive control of human papillomavirus infections and related diseases.

Bosch FX, Broker TR, Forman D, Moscicki AB, Gillison ML, Doorbar J, Stern PL, Stanley M, Arbyn M, Poljak M, Cuzick J, Castle PE, Schiller JT, Markowitz LE, Fisher WA, Canfell K, Denny LA, Franco EL, Steben M, Kane MA, Schiffman M, Meijer CJ, Sankaranarayanan R, Castellsagué X, Kim JJ, Brotons M, Alemany L, Albero G, Diaz M, de Sanjosé S; Authors of the ICO Monograph ‘Comprehensive Control of HPV Infections and Related Diseases’ Vaccine Volume 30, Supplement 5, 2012.

Vaccine. 2013 Nov 22;31 Suppl 8:I1-31. doi: 10.1016/j.vaccine.2013.07.026. Review.

39.

Immunosuppression facilitates the reactivation of latent papillomavirus infections.

Maglennon GA, McIntosh PB, Doorbar J.

J Virol. 2014 Jan;88(1):710-6. doi: 10.1128/JVI.02589-13. Epub 2013 Oct 30.

40.

The E4 protein; structure, function and patterns of expression.

Doorbar J.

Virology. 2013 Oct;445(1-2):80-98. doi: 10.1016/j.virol.2013.07.008. Epub 2013 Sep 7.

41.

Expression of betapapillomavirus oncogenes increases the number of keratinocytes with stem cell-like properties.

Hufbauer M, Biddle A, Borgogna C, Gariglio M, Doorbar J, Storey A, Pfister H, Mackenzie I, Akgül B.

J Virol. 2013 Nov;87(22):12158-65. doi: 10.1128/JVI.01510-13. Epub 2013 Sep 4.

42.

Latent papillomavirus infections and their regulation.

Doorbar J.

Curr Opin Virol. 2013 Aug;3(4):416-21. doi: 10.1016/j.coviro.2013.06.003. Epub 2013 Jun 29. Review.

PMID:
23816390
43.

ONCOGENIC HUMAN PAPILLOMAVIRUSES: High-Risk Human Papillomaviruses: Towards a Better Understanding of the Mechanisms of Viral Transformation, Latency and Immune-Escape.

Cid Arregui A, Gariglio P, Kanda T, Doorbar J.

Open Virol J. 2012;6:160-2. doi: 10.2174/1874357901206010160. Epub 2012 Dec 28. No abstract available.

44.

The biology of papillomavirus latency.

Maglennon GA, Doorbar J.

Open Virol J. 2012;6:190-7. doi: 10.2174/1874357901206010190. Epub 2012 Dec 28.

45.

E4 antibodies facilitate detection and type-assignment of active HPV infection in cervical disease.

Griffin H, Wu Z, Marnane R, Dewar V, Molijn A, Quint W, Van Hoof C, Struyf F, Colau B, Jenkins D, Doorbar J.

PLoS One. 2012;7(12):e49974. doi: 10.1371/journal.pone.0049974. Epub 2012 Dec 3.

46.

The biology and life-cycle of human papillomaviruses.

Doorbar J, Quint W, Banks L, Bravo IG, Stoler M, Broker TR, Stanley MA.

Vaccine. 2012 Nov 20;30 Suppl 5:F55-70. doi: 10.1016/j.vaccine.2012.06.083. Review.

PMID:
23199966
47.

Human papillomavirus type 8 interferes with a novel C/EBPβ-mediated mechanism of keratinocyte CCL20 chemokine expression and Langerhans cell migration.

Sperling T, Ołdak M, Walch-Rückheim B, Wickenhauser C, Doorbar J, Pfister H, Malejczyk M, Majewski S, Keates AC, Smola S.

PLoS Pathog. 2012;8(7):e1002833. doi: 10.1371/journal.ppat.1002833. Epub 2012 Jul 26.

48.

Quantitative measurement of human papillomavirus type 16 e5 oncoprotein levels in epithelial cell lines by mass spectrometry.

Sahab Z, Sudarshan SR, Liu X, Zhang Y, Kirilyuk A, Kamonjoh CM, Simic V, Dai Y, Byers SW, Doorbar J, Suprynowicz FA, Schlegel R.

J Virol. 2012 Sep;86(17):9465-73. doi: 10.1128/JVI.01032-12. Epub 2012 Jun 27.

49.

HPV-18 E2^E4 chimera: 2 new spliced transcripts and proteins induced by keratinocyte differentiation.

Tan CL, Gunaratne J, Lai D, Carthagena L, Wang Q, Xue YZ, Quek LS, Doorbar J, Bachelerie F, Thierry F, Bellanger S.

Virology. 2012 Jul 20;429(1):47-56. doi: 10.1016/j.virol.2012.03.023. Epub 2012 Apr 27.

50.

Reconstruction of human papillomavirus type 16-mediated early-stage neoplasia implicates E6/E7 deregulation and the loss of contact inhibition in neoplastic progression.

Isaacson Wechsler E, Wang Q, Roberts I, Pagliarulo E, Jackson D, Untersperger C, Coleman N, Griffin H, Doorbar J.

J Virol. 2012 Jun;86(11):6358-64. doi: 10.1128/JVI.07069-11. Epub 2012 Mar 28.

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