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Items: 1 to 50 of 287

1.

S. Jonathan Singer: A man who loved ideas and detested walls.

Doolittle RF.

Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):3550-3551. doi: 10.1073/pnas.1703437114. Epub 2017 Mar 21. No abstract available.

2.

The conversion of fibrinogen to fibrin: A brief history of some key events.

Doolittle RF.

Matrix Biol. 2017 Jul;60-61:5-7. doi: 10.1016/j.matbio.2016.08.002. Epub 2016 Aug 9. Review.

PMID:
27519977
3.

Some Important Milestones in the Field of Blood Clotting.

Doolittle RF.

J Innate Immun. 2016;8(1):23-9. doi: 10.1159/000442470. Epub 2015 Dec 15. Review.

4.

Bioinformatic Characterization of Genes and Proteins Involved in Blood Clotting in Lampreys.

Doolittle RF.

J Mol Evol. 2015 Oct;81(3-4):121-30. doi: 10.1007/s00239-015-9701-0. Epub 2015 Oct 5.

5.

Clotting of mammalian fibrinogens by papain: a re-examination.

Doolittle RF.

Biochemistry. 2014 Oct 28;53(42):6687-94. doi: 10.1021/bi5010987. Epub 2014 Oct 15.

6.

TRF2 and the evolution of the bilateria.

Duttke SH, Doolittle RF, Wang YL, Kadonaga JT.

Genes Dev. 2014 Oct 1;28(19):2071-6. doi: 10.1101/gad.250563.114.

7.

Health websites: accessibility and usability for American sign language users.

Kushalnagar P, Naturale J, Paludneviciene R, Smith SR, Werfel E, Doolittle R, Jacobs S, DeCaro J.

Health Commun. 2015;30(8):830-7. doi: 10.1080/10410236.2013.853226. Epub 2014 Jun 5.

8.

Correlating structure and function during the evolution of fibrinogen-related domains.

Doolittle RF, McNamara K, Lin K.

Protein Sci. 2012 Dec;21(12):1808-23. doi: 10.1002/pro.2177. Review.

9.

Peptide-derivatized albumins that inhibit fibrin polymerization.

Watson JW, Doolittle RF.

Biochemistry. 2011 Nov 15;50(45):9923-7. doi: 10.1021/bi201406c. Epub 2011 Oct 19.

PMID:
22010909
10.

Clots vs bugs: who's ahead?

Doolittle RF.

Blood. 2011 Sep 1;118(9):2382-4. doi: 10.1182/blood-2011-06-357574. No abstract available.

PMID:
21885608
11.

The protochordate Ciona intestinalis has a protein like full-length vertebrate fibrinogen.

Doolittle RF.

J Innate Immun. 2012;4(2):219-22. doi: 10.1159/000329823. Epub 2011 Aug 20.

12.

Coagulation in vertebrates with a focus on evolution and inflammation.

Doolittle RF.

J Innate Immun. 2011;3(1):9-16. doi: 10.1159/000321005. Epub 2010 Oct 28. Review.

13.

The roots of bioinformatics in protein evolution.

Doolittle RF.

PLoS Comput Biol. 2010 Jul 29;6(7):e1000875. doi: 10.1371/journal.pcbi.1000875. Review. No abstract available.

14.

Climate change and the integrity of science.

Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, Berenbaum MR, Berlin OB, Bjorkman PJ, Blackburn E, Blamont JE, Botchan MR, Boyer JS, Boyle EA, Branton D, Briggs SP, Briggs WR, Brill WJ, Britten RJ, Broecker WS, Brown JH, Brown PO, Brunger AT, Cairns J Jr, Canfield DE, Carpenter SR, Carrington JC, Cashmore AR, Castilla JC, Cazenave A, Chapin FS 3rd, Ciechanover AJ, Clapham DE, Clark WC, Clayton RN, Coe MD, Conwell EM, Cowling EB, Cowling RM, Cox CS, Croteau RB, Crothers DM, Crutzen PJ, Daily GC, Dalrymple GB, Dangl JL, Darst SA, Davies DR, Davis MB, De Camilli PV, Dean C, DeFries RS, Deisenhofer J, Delmer DP, DeLong EF, DeRosier DJ, Diener TO, Dirzo R, Dixon JE, Donoghue MJ, Doolittle RF, Dunne T, Ehrlich PR, Eisenstadt SN, Eisner T, Emanuel KA, Englander SW, Ernst WG, Falkowski PG, Feher G, Ferejohn JA, Fersht A, Fischer EH, Fischer R, Flannery KV, Frank J, Frey PA, Fridovich I, Frieden C, Futuyma DJ, Gardner WR, Garrett CJ, Gilbert W, Goldberg RB, Goodenough WH, Goodman CS, Goodman M, Greengard P, Hake S, Hammel G, Hanson S, Harrison SC, Hart SR, Hartl DL, Haselkorn R, Hawkes K, Hayes JM, Hille B, Hökfelt T, House JS, Hout M, Hunten DM, Izquierdo IA, Jagendorf AT, Janzen DH, Jeanloz R, Jencks CS, Jury WA, Kaback HR, Kailath T, Kay P, Kay SA, Kennedy D, Kerr A, Kessler RC, Khush GS, Kieffer SW, Kirch PV, Kirk K, Kivelson MG, Klinman JP, Klug A, Knopoff L, Kornberg H, Kutzbach JE, Lagarias JC, Lambeck K, Landy A, Langmuir CH, Larkins BA, Le Pichon XT, Lenski RE, Leopold EB, Levin SA, Levitt M, Likens GE, Lippincott-Schwartz J, Lorand L, Lovejoy CO, Lynch M, Mabogunje AL, Malone TF, Manabe S, Marcus J, Massey DS, McWilliams JC, Medina E, Melosh HJ, Meltzer DJ, Michener CD, Miles EL, Mooney HA, Moore PB, Morel FM, Mosley-Thompson ES, Moss B, Munk WH, Myers N, Nair GB, Nathans J, Nester EW, Nicoll RA, Novick RP, O'Connell JF, Olsen PE, Opdyke ND, Oster GF, Ostrom E, Pace NR, Paine RT, Palmiter RD, Pedlosky J, Petsko GA, Pettengill GH, Philander SG, Piperno DR, Pollard TD, Price PB Jr, Reichard PA, Reskin BF, Ricklefs RE, Rivest RL, Roberts JD, Romney AK, Rossmann MG, Russell DW, Rutter WJ, Sabloff JA, Sagdeev RZ, Sahlins MD, Salmond A, Sanes JR, Schekman R, Schellnhuber J, Schindler DW, Schmitt J, Schneider SH, Schramm VL, Sederoff RR, Shatz CJ, Sherman F, Sidman RL, Sieh K, Simons EL, Singer BH, Singer MF, Skyrms B, Sleep NH, Smith BD, Snyder SH, Sokal RR, Spencer CS, Steitz TA, Strier KB, Südhof TC, Taylor SS, Terborgh J, Thomas DH, Thompson LG, Tjian RT, Turner MG, Uyeda S, Valentine JW, Valentine JS, Van Etten JL, van Holde KE, Vaughan M, Verba S, von Hippel PH, Wake DB, Walker A, Walker JE, Watson EB, Watson PJ, Weigel D, Wessler SR, West-Eberhard MJ, White TD, Wilson WJ, Wolfenden RV, Wood JA, Woodwell GM, Wright HE Jr, Wu C, Wunsch C, Zoback ML.

Science. 2010 May 7;328(5979):689-90. doi: 10.1126/science.328.5979.689. No abstract available. Erratum in: Science. 2010 May 14;328(5980):826.

15.

Step-by-step evolution of vertebrate blood coagulation.

Doolittle RF.

Cold Spring Harb Symp Quant Biol. 2009;74:35-40. doi: 10.1101/sqb.2009.74.001. Epub 2009 Aug 10. Review.

PMID:
19667012
16.

Two families of synthetic peptides that enhance fibrin turbidity and delay fibrinolysis by different mechanisms.

Pandi L, Kollman JM, Lopez-Lira F, Burrows JM, Riley M, Doolittle RF.

Biochemistry. 2009 Aug 4;48(30):7201-8. doi: 10.1021/bi900647g.

PMID:
19588915
17.

Evolution of the fibrinogen gamma' chain: implications for the binding of factor XIII, thrombin and platelets.

Doolittle RF, Hong S, Wilcox D.

J Thromb Haemost. 2009 Aug;7(8):1431-3. doi: 10.1111/j.1538-7836.2009.03519.x. Epub 2009 Jun 22. No abstract available.

18.

3D airway reconstruction using visible human data set and human casts with comparison to morphometric data.

Robinson RJ, Russo J, Doolittle RL.

Anat Rec (Hoboken). 2009 Jul;292(7):1028-44. doi: 10.1002/ar.20898.

19.

Crystal structure of human fibrinogen.

Kollman JM, Pandi L, Sawaya MR, Riley M, Doolittle RF.

Biochemistry. 2009 May 12;48(18):3877-86. doi: 10.1021/bi802205g.

PMID:
19296670
20.

Evolution of the contact phase of vertebrate blood coagulation.

Ponczek MB, Gailani D, Doolittle RF.

J Thromb Haemost. 2008 Nov;6(11):1876-83. doi: 10.1111/j.1538-7836.2008.03143.x. Epub 2008 Aug 28. Erratum in: J Thromb Haemost. 2008 Dec;6(12):2228.

21.

Searching for differences between fibrinogen and fibrin that affect the initiation of fibrinolysis.

Doolittle RF.

Cardiovasc Hematol Agents Med Chem. 2008 Jul;6(3):181-9. Review.

PMID:
18673232
22.

Genomic evidence for a simpler clotting scheme in jawless vertebrates.

Doolittle RF, Jiang Y, Nand J.

J Mol Evol. 2008 Feb;66(2):185-96. doi: 10.1007/s00239-008-9074-8. Epub 2008 Feb 19.

PMID:
18283387
23.

Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini.

Doolittle RF, Pandi L.

Biochemistry. 2007 Sep 4;46(35):10033-8. Epub 2007 Aug 10.

PMID:
17688324
24.

Use of asthmatic pulmonary function test data to predict lung deposition.

Robinson RJ, Doolittle RL, Diflorio JN.

J Aerosol Med. 2007 Summer;20(2):141-62.

PMID:
17536952
25.

The occurrence of type S1A serine proteases in sponge and jellyfish.

Rojas A, Doolittle RF.

J Mol Evol. 2006 Dec;55(6):790-4.

PMID:
17476731
27.

Binding of synthetic B knobs to fibrinogen changes the character of fibrin and inhibits its ability to activate tissue plasminogen activator and its destruction by plasmin.

Doolittle RF, Pandi L.

Biochemistry. 2006 Feb 28;45(8):2657-67. Erratum in: Biochemistry. 2006 Apr 4;45(13):4338.

PMID:
16489759
28.

Natively unfolded regions of the vertebrate fibrinogen molecule.

Doolittle RF, Kollman JM.

Proteins. 2006 May 1;63(2):391-7. Review.

PMID:
16288455
29.

Evolutionary aspects of whole-genome biology.

Doolittle RF.

Curr Opin Struct Biol. 2005 Jun;15(3):248-53. Review.

PMID:
15963888
30.

Martin David Kamen (27 August 1913 - 31 August 2002).

Doolittle RF.

Proc Am Philos Soc. 2004 Dec;148(4):499-503. No abstract available.

PMID:
15818877
31.

Unusual non-crystallographic symmetry in crystals of a 420 kDa crustacean clottable protein.

Kollman JM, Doolittle RF.

Acta Crystallogr D Biol Crystallogr. 2005 Apr;61(Pt 4):485-9. Epub 2005 Mar 24.

PMID:
15805605
32.

Molecular cloning of a new cDNA and expression of 3-hydroxy-3-methylglutaryl-CoA synthase gene from Hevea brasiliensis.

Sirinupong N, Suwanmanee P, Doolittle RF, Suvachitanont W.

Planta. 2005 Jun;221(4):502-12. Epub 2005 Mar 3.

PMID:
15744497
33.

Phylogeny determined by protein domain content.

Yang S, Doolittle RF, Bourne PE.

Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):373-8. Epub 2005 Jan 3.

34.

Some comments on John Ferry's most enduring paper.

Doolittle RF.

Biophys Chem. 2004 Dec 20;112(2-3):177-80.

35.

Determining the crystal structure of fibrinogen.

Doolittle RF.

J Thromb Haemost. 2004 May;2(5):683-9.

36.

Re: Regulatory Toxicology and Pharmacology.

Axelson O, Balbus JM, Cohen G, Davis D, Donnay A, Doolittle R, Duran BM, Egilman D, Epstein SS, Goldman L, Grandjean P, Hansen ES, Heltne P, Huff J, Infante P, Jacobson MF, Joshi TK, LaDou J, Landrigan PJ, Lee PR, Lockwood AH, MacGregor G, Melnick R, Messing K, Needleman H, Ozonoff D, Ravanesi B, Richter ED, Sass J, Schubert D, Suzuki D, Teitelbaum D, Temple NJ, Terracini B, Thompson A, Tickner J, Tomatis L, Upton AC, Whyatt RM, Wigmore D, Wilson T, Wing SB, Sharpe VA.

Int J Occup Environ Health. 2003 Oct-Dec;9(4):386-9; author reply 389-90. No abstract available.

PMID:
14664493
37.

Editorial policies on financial disclosure.

Jacobson MF, Sharpe VA, Angell M, Ashford NA, Blum A, Chary LK, Cho M, Coull BC, Davis D, Doolittle RF, Egilman D, Epstein SS, Greenberg M, Hooper K, Huff J, Joshi TK, Krimsky S, LaDou J, Levenstein C, Miles S, Needleman H, Pellegrino ED, Ravanesi B, Sass J, Schecter A, Schneiderman JS, Schubert D, Soffritti M, Suzuki D, Takaro TK, Temple NJ, Terracini B, Thompson A, Wallinga D, Wing S.

Nat Neurosci. 2003 Oct;6(10):1001. No abstract available.

PMID:
14513030
38.

X-ray crystallographic studies on fibrinogen and fibrin.

Doolittle RF.

J Thromb Haemost. 2003 Jul;1(7):1559-65. Review.

39.

The evolution of vertebrate blood coagulation as viewed from a comparison of puffer fish and sea squirt genomes.

Jiang Y, Doolittle RF.

Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7527-32. Epub 2003 Jun 13.

40.

Some notes on crystallizing fibrinogen and fibrin fragments.

Doolittle RF.

Biophys Chem. 2003;100(1-3):307-13.

PMID:
12646373
41.
42.
43.

The grand assault.

Doolittle RF.

Nature. 2002 Oct 3;419(6906):493-4. No abstract available. Erratum in: Nature 2002 Oct 24;419(6909):799.

PMID:
12368861
44.

Crystal structure of fragment D from lamprey fibrinogen complexed with the peptide Gly-His-Arg-Pro-amide.

Yang Z, Spraggon G, Pandi L, Everse SJ, Riley M, Doolittle RF.

Biochemistry. 2002 Aug 13;41(32):10218-24.

PMID:
12162736
45.

Biodiversity: microbial genomes multiply.

Doolittle RF.

Nature. 2002 Apr 18;416(6882):697-700. No abstract available.

PMID:
11961543
46.

Bacterial actins? An evolutionary perspective.

Doolittle RF, York AL.

Bioessays. 2002 Apr;24(4):293-6. Review.

PMID:
11948613
47.

Kindergarten health assessment reports: what do schools really learn from them?

Clemens C, Doolittle RP, Hoyle M.

Clin Pediatr (Phila). 2002 Mar;41(2):93-8.

PMID:
11931338
48.

Crystal structure of native chicken fibrinogen at 2.7 A resolution.

Yang Z, Kollman JM, Pandi L, Doolittle RF.

Biochemistry. 2001 Oct 23;40(42):12515-23.

PMID:
11601975
49.

Determining divergence times with protein clocks.

Doolittle RF, Feng DF, Cho G.

Biol Bull. 1999 Jun;196(3):356-7; discussion 357-8. No abstract available.

PMID:
11536911
50.

Crystal structure studies on fibrinogen and fibrin.

Doolittle RF, Yang Z, Mochalkin I.

Ann N Y Acad Sci. 2001;936:31-43. Review.

PMID:
11460486

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