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Items: 39

1.

Preface.

Clarke C, Dontu G, Hilton H, Meier-Abt F, Sartorius C.

J Mammary Gland Biol Neoplasia. 2015 Jun;20(1-2):5-7. doi: 10.1007/s10911-015-9345-0. No abstract available.

PMID:
26385464
2.

Of mice and women: a comparative tissue biology perspective of breast stem cells and differentiation.

Dontu G, Ince TA.

J Mammary Gland Biol Neoplasia. 2015 Jun;20(1-2):51-62. doi: 10.1007/s10911-015-9341-4. Epub 2015 Aug 19. Review.

3.

Modeling the breast cancer bone metastatic niche in complex three-dimensional cocultures.

Marlow R, Dontu G.

Methods Mol Biol. 2015;1293:213-20. doi: 10.1007/978-1-4939-2519-3_12.

PMID:
26040690
4.

Models of breast morphogenesis based on localization of stem cells in the developing mammary lobule.

Honeth G, Schiavinotto T, Vaggi F, Marlow R, Kanno T, Shinomiya I, Lombardi S, Buchupalli B, Graham R, Gazinska P, Ramalingam V, Burchell J, Purushotham AD, Pinder SE, Csikasz-Nagy A, Dontu G.

Stem Cell Reports. 2015 Apr 14;4(4):699-711. doi: 10.1016/j.stemcr.2015.02.013. Epub 2015 Mar 26.

5.

Growth hormone is secreted by normal breast epithelium upon progesterone stimulation and increases proliferation of stem/progenitor cells.

Lombardi S, Honeth G, Ginestier C, Shinomiya I, Marlow R, Buchupalli B, Gazinska P, Brown J, Catchpole S, Liu S, Barkan A, Wicha M, Purushotham A, Burchell J, Pinder S, Dontu G.

Stem Cell Reports. 2014 Jun 3;2(6):780-93. doi: 10.1016/j.stemcr.2014.05.005. eCollection 2014 Jun 3.

6.

Aldehyde dehydrogenase and estrogen receptor define a hierarchy of cellular differentiation in the normal human mammary epithelium.

Honeth G, Lombardi S, Ginestier C, Hur M, Marlow R, Buchupalli B, Shinomiya I, Gazinska P, Bombelli S, Ramalingam V, Purushotham AD, Pinder SE, Dontu G.

Breast Cancer Res. 2014 May 27;16(3):R52. doi: 10.1186/bcr3663.

7.

A novel model of dormancy for bone metastatic breast cancer cells.

Marlow R, Honeth G, Lombardi S, Cariati M, Hessey S, Pipili A, Mariotti V, Buchupalli B, Foster K, Bonnet D, Grigoriadis A, Rameshwar P, Purushotham A, Tutt A, Dontu G.

Cancer Res. 2013 Dec 1;73(23):6886-99. doi: 10.1158/0008-5472.CAN-13-0991. Epub 2013 Oct 21.

8.

Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors.

Schott AF, Landis MD, Dontu G, Griffith KA, Layman RM, Krop I, Paskett LA, Wong H, Dobrolecki LE, Lewis MT, Froehlich AM, Paranilam J, Hayes DF, Wicha MS, Chang JC.

Clin Cancer Res. 2013 Mar 15;19(6):1512-24. doi: 10.1158/1078-0432.CCR-11-3326. Epub 2013 Jan 22.

9.

Delineation of breast cancer cell hierarchy identifies the subset responsible for dormancy.

Patel SA, Ramkissoon SH, Bryan M, Pliner LF, Dontu G, Patel PS, Amiri S, Pine SR, Rameshwar P.

Sci Rep. 2012;2:906. doi: 10.1038/srep00906. Epub 2012 Nov 30.

10.

International expert consensus on primary systemic therapy in the management of early breast cancer: highlights of the Fourth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2010).

Berruti A, Generali D, Kaufmann M, Puztai L, Curigliano G, Aglietta M, Gianni L, Miller WR, Untch M, Sotiriou C, Daidone M, Conte P, Kennedy D, Damia G, Petronini P, Di Cosimo S, Bruzzi P, Dowsett M, Desmedt C, Mansel RE, Olivetti L, Tondini C, Sapino A, Fenaroli P, Tortora G, Thorne H, Bertolini F, Ferrozzi F, Danova M, Tagliabue E, de Azambuja E, Makris A, Tampellini M, Dontu G, Van't Veer L, Harris AL, Fox SB, Dogliotti L, Bottini A.

J Natl Cancer Inst Monogr. 2011;2011(43):147-51. doi: 10.1093/jncimonographs/lgr037.

PMID:
22043063
11.

Dicer-mediated upregulation of BCRP confers tamoxifen resistance in human breast cancer cells.

Selever J, Gu G, Lewis MT, Beyer A, Herynk MH, Covington KR, Tsimelzon A, Dontu G, Provost P, Di Pietro A, Boumendjel A, Albain K, Miele L, Weiss H, Barone I, Ando S, Fuqua SA.

Clin Cancer Res. 2011 Oct 15;17(20):6510-21. doi: 10.1158/1078-0432.CCR-11-1403. Epub 2011 Aug 30.

12.

Xenotransplantation of breast cancers.

Cariati M, Marlow R, Dontu G.

Methods Mol Biol. 2011;731:471-82. doi: 10.1007/978-1-61779-080-5_38.

PMID:
21516430
13.

Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks.

Liu S, Ginestier C, Ou SJ, Clouthier SG, Patel SH, Monville F, Korkaya H, Heath A, Dutcher J, Kleer CG, Jung Y, Dontu G, Taichman R, Wicha MS.

Cancer Res. 2011 Jan 15;71(2):614-24. doi: 10.1158/0008-5472.CAN-10-0538. Epub 2011 Jan 11. Erratum in: Cancer Res. 2011 Mar 15;71(6):2407.

14.

MicroRNAs: shortcuts in dealing with molecular complexity?

Dontu G, de Rinaldis E.

Breast Cancer Res. 2010;12(1):301. doi: 10.1186/bcr2455.

15.

CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts.

Ginestier C, Liu S, Diebel ME, Korkaya H, Luo M, Brown M, Wicinski J, Cabaud O, Charafe-Jauffret E, Birnbaum D, Guan JL, Dontu G, Wicha MS.

J Clin Invest. 2010 Feb;120(2):485-97. doi: 10.1172/JCI39397. Epub 2010 Jan 4.

16.

Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer.

Charafe-Jauffret E, Ginestier C, Iovino F, Tarpin C, Diebel M, Esterni B, Houvenaeghel G, Extra JM, Bertucci F, Jacquemier J, Xerri L, Dontu G, Stassi G, Xiao Y, Barsky SH, Birnbaum D, Viens P, Wicha MS.

Clin Cancer Res. 2010 Jan 1;16(1):45-55. doi: 10.1158/1078-0432.CCR-09-1630. Epub 2009 Dec 22.

17.

Targeting breast stem cells with the cancer preventive compounds curcumin and piperine.

Kakarala M, Brenner DE, Korkaya H, Cheng C, Tazi K, Ginestier C, Liu S, Dontu G, Wicha MS.

Breast Cancer Res Treat. 2010 Aug;122(3):777-85. doi: 10.1007/s10549-009-0612-x. Epub 2009 Nov 7.

18.

Breast cancer metastasis: challenges and opportunities.

Lu J, Steeg PS, Price JE, Krishnamurthy S, Mani SA, Reuben J, Cristofanilli M, Dontu G, Bidaut L, Valero V, Hortobagyi GN, Yu D.

Cancer Res. 2009 Jun 15;69(12):4951-3. doi: 10.1158/0008-5472.CAN-09-0099. Epub 2009 May 26. No abstract available.

19.

Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis.

Huang EH, Hynes MJ, Zhang T, Ginestier C, Dontu G, Appelman H, Fields JZ, Wicha MS, Boman BM.

Cancer Res. 2009 Apr 15;69(8):3382-9. doi: 10.1158/0008-5472.CAN-08-4418. Epub 2009 Mar 31.

20.

Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature.

Charafe-Jauffret E, Ginestier C, Iovino F, Wicinski J, Cervera N, Finetti P, Hur MH, Diebel ME, Monville F, Dutcher J, Brown M, Viens P, Xerri L, Bertucci F, Stassi G, Dontu G, Birnbaum D, Wicha MS.

Cancer Res. 2009 Feb 15;69(4):1302-13. doi: 10.1158/0008-5472.CAN-08-2741. Epub 2009 Feb 3.

21.

[Stem cells and epithelial cancers: the example of breast cancer].

Charafe-Jauffret E, Ginestier C, Monville F, Wicinski J, Bertucci F, Viens P, Xerri L, Cabaud O, Dontu G, Wicha MS, Birnbaum D.

Ann Pathol. 2008 Nov;28 Spec No 1(1):S30-2. doi: 10.1016/j.annpat.2008.09.005. Epub 2008 Oct 17. French. No abstract available.

PMID:
18984292
22.

Breast cancer stem cell markers - the rocky road to clinical applications.

Dontu G.

Breast Cancer Res. 2008;10(5):110. doi: 10.1186/bcr2130. Epub 2008 Sep 15.

23.

Monitoring serial changes in circulating human breast cancer cells in murine xenograft models.

Eliane JP, Repollet M, Luker KE, Brown M, Rae JM, Dontu G, Schott AF, Wicha M, Doyle GV, Hayes DF, Luker GD.

Cancer Res. 2008 Jul 15;68(14):5529-32. doi: 10.1158/0008-5472.CAN-08-0630.

24.

Cancer stem cells in breast: current opinion and future challenges.

Charafe-Jauffret E, Monville F, Ginestier C, Dontu G, Birnbaum D, Wicha MS.

Pathobiology. 2008;75(2):75-84. doi: 10.1159/000123845. Epub 2008 Jun 10. Review.

25.

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome.

Ginestier C, Hur MH, Charafe-Jauffret E, Monville F, Dutcher J, Brown M, Jacquemier J, Viens P, Kleer CG, Liu S, Schott A, Hayes D, Birnbaum D, Wicha MS, Dontu G.

Cell Stem Cell. 2007 Nov;1(5):555-67. doi: 10.1016/j.stem.2007.08.014.

26.

BRCA1 regulates human mammary stem/progenitor cell fate.

Liu S, Ginestier C, Charafe-Jauffret E, Foco H, Kleer CG, Merajver SD, Dontu G, Wicha MS.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1680-5. doi: 10.1073/pnas.0711613105. Epub 2008 Jan 29.

27.

[The cancer stem cell: the breast cancer driver].

Ginestier C, Korkaya H, Dontu G, Birnbaum D, Wicha MS, Charafe-Jauffret E.

Med Sci (Paris). 2007 Dec;23(12):1133-9. Review. French.

28.

Breast cancer stem cells-research opportunities utilizing mathematical modeling.

Ashkenazi R, Jackson TL, Dontu G, Wicha MS.

Stem Cell Rev. 2007 Jun;3(2):176-82. Review.

PMID:
17873350
29.

Stem cells in mammary development and carcinogenesis: implications for prevention and treatment.

Dontu G, Liu S, Wicha MS.

Stem Cell Rev. 2005;1(3):207-13. Review.

PMID:
17142857
30.

Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells.

Liu S, Dontu G, Mantle ID, Patel S, Ahn NS, Jackson KW, Suri P, Wicha MS.

Cancer Res. 2006 Jun 15;66(12):6063-71.

31.

Cancer stem cells: an old idea--a paradigm shift.

Wicha MS, Liu S, Dontu G.

Cancer Res. 2006 Feb 15;66(4):1883-90; discussion 1895-6.

32.

Mammary stem cells, self-renewal pathways, and carcinogenesis.

Liu S, Dontu G, Wicha MS.

Breast Cancer Res. 2005;7(3):86-95. Epub 2005 Mar 30. Review.

33.

Survival of mammary stem cells in suspension culture: implications for stem cell biology and neoplasia.

Dontu G, Wicha MS.

J Mammary Gland Biol Neoplasia. 2005 Jan;10(1):75-86. Review.

34.

Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells.

Dontu G, Jackson KW, McNicholas E, Kawamura MJ, Abdallah WM, Wicha MS.

Breast Cancer Res. 2004;6(6):R605-15. Epub 2004 Aug 16.

35.

Breast cancer, stem/progenitor cells and the estrogen receptor.

Dontu G, El-Ashry D, Wicha MS.

Trends Endocrinol Metab. 2004 Jul;15(5):193-7. Review.

PMID:
15223047
36.

Stem cells in normal breast development and breast cancer.

Dontu G, Al-Hajj M, Abdallah WM, Clarke MF, Wicha MS.

Cell Prolif. 2003 Oct;36 Suppl 1:59-72. Review.

37.

In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells.

Dontu G, Abdallah WM, Foley JM, Jackson KW, Clarke MF, Kawamura MJ, Wicha MS.

Genes Dev. 2003 May 15;17(10):1253-70.

38.

[The prevalence of antibodies to the hepatitis C virus (HCV) in patients with post-transfusional hepatitis and blood donors in Moldova].

Iancu L, Turcu T, Apetrei C, Porumb S, Dimitriu S, Donţu G, Mândru R, Moraru E, Duca M.

Bacteriol Virusol Parazitol Epidemiol. 1993 Jan-Jun;38(1-2):76-80. Romanian. No abstract available.

PMID:
9132116
39.

A new staining technique for the identification of Cryptosporidium oocysts in faecal smears.

Ungureanu EM, Dontu GE.

Trans R Soc Trop Med Hyg. 1992 Nov-Dec;86(6):638. No abstract available.

PMID:
1283794

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