Sort by
Items per page

Send to

Choose Destination

Search results

Items: 38


Platelet heterogeneity in activation-induced glycoprotein shedding: functional effects.

Baaten CCFMJ, Swieringa F, Misztal T, Mastenbroek TG, Feijge MAH, Bock PE, Donners MMPC, Collins PW, Li R, van der Meijden PEJ, Heemskerk JWM.

Blood Adv. 2018 Sep 25;2(18):2320-2331. doi: 10.1182/bloodadvances.2017011544.


Colors of attraction: Modeling insect flight to light behavior.

Donners M, van Grunsven RHA, Groenendijk D, van Langevelde F, Bikker JW, Longcore T, Veenendaal E.

J Exp Zool A Ecol Integr Physiol. 2018 Jun 26. doi: 10.1002/jez.2188. [Epub ahead of print]


A Disintegrin and Metalloproteases (ADAMs) in Cardiovascular, Metabolic and Inflammatory Diseases: Aspects for Theranostic Approaches.

van der Vorst EPC, Weber C, Donners MMPC.

Thromb Haemost. 2018 Jul;118(7):1167-1175. doi: 10.1055/s-0038-1660479. Epub 2018 Jun 6.


Message in a Microbottle: Modulation of Vascular Inflammation and Atherosclerosis by Extracellular Vesicles.

van der Vorst EPC, de Jong RJ, Donners MMPC.

Front Cardiovasc Med. 2018 Jan 22;5:2. doi: 10.3389/fcvm.2018.00002. eCollection 2018. Review.


Heterogeneity of atherosclerotic plaque macrophage origin, phenotype and functions: Implications for treatment.

Nagenborg J, Goossens P, Biessen EAL, Donners MMPC.

Eur J Pharmacol. 2017 Dec 5;816:14-24. doi: 10.1016/j.ejphar.2017.10.005. Epub 2017 Oct 5. Review.


Whole body and hematopoietic ADAM8 deficiency does not influence advanced atherosclerotic lesion development, despite its association with human plaque progression.

Theodorou K, van der Vorst EPC, Gijbels MJ, Wolfs IMJ, Jeurissen M, Theelen TL, Sluimer JC, Wijnands E, Cleutjens JP, Li Y, Jansen Y, Weber C, Ludwig A, Bentzon JF, Bartsch JW, Biessen EAL, Donners MMPC.

Sci Rep. 2017 Sep 15;7(1):11670. doi: 10.1038/s41598-017-10549-x.


Disease- or Storage-Associated Structural Modifications Are Unlikely to Explain HDL Pro-inflammatory Effects on Macrophages.

van der Vorst EPC, Theodorou K, Biessen EAL, Donners MMPC.

Cell Metab. 2017 Jul 5;26(1):4-5. doi: 10.1016/j.cmet.2017.05.017. Epub 2017 Jun 22.


Response of bats to light with different spectra: light-shy and agile bat presence is affected by white and green, but not red light.

Spoelstra K, van Grunsven RHA, Ramakers JJC, Ferguson KB, Raap T, Donners M, Veenendaal EM, Visser ME.

Proc Biol Sci. 2017 May 31;284(1855). pii: 20170075. doi: 10.1098/rspb.2017.0075.


HDL and macrophages: explaining the clinical failures and advancing HDL-based therapeutics in cardiovascular diseases?

van der Vorst EPC, Theodorou K, Biessen EAL, Donners MMPC.

Expert Rev Cardiovasc Ther. 2017 May;15(5):343-344. doi: 10.1080/14779072.2017.1313115. Epub 2017 Apr 10. No abstract available.


Fine Tuning Cell Migration by a Disintegrin and Metalloproteinases.

Dreymueller D, Theodorou K, Donners M, Ludwig A.

Mediators Inflamm. 2017;2017:9621724. doi: 10.1155/2017/9621724. Epub 2017 Feb 5. Review.


High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling.

van der Vorst EPC, Theodorou K, Wu Y, Hoeksema MA, Goossens P, Bursill CA, Aliyev T, Huitema LFA, Tas SW, Wolfs IMJ, Kuijpers MJE, Gijbels MJ, Schalkwijk CG, Koonen DPY, Abdollahi-Roodsaz S, McDaniels K, Wang CC, Leitges M, Lawrence T, Plat J, Van Eck M, Rye KA, Touqui L, de Winther MPJ, Biessen EAL, Donners MMPC.

Cell Metab. 2017 Jan 10;25(1):197-207. doi: 10.1016/j.cmet.2016.10.013. Epub 2016 Nov 17.


Prevention of oxLDL uptake leads to decreased atherosclerosis in hematopoietic NPC1-deficient Ldlr-/- mice.

Jeurissen MLJ, Walenbergh SMA, Houben T, Gijbels MJJ, Li J, Hendrikx T, Oligschlaeger Y, van Gorp PJ, Binder CJ, Donners MMPC, Shiri-Sverdlov R.

Atherosclerosis. 2016 Dec;255:59-65. doi: 10.1016/j.atherosclerosis.2016.10.038. Epub 2016 Oct 20.


Cathepsin K Deficiency Prevents the Aggravated Vascular Remodeling Response to Flow Cessation in ApoE-/- Mice.

Donners MM, Bai L, Lutgens SP, Wijnands E, Johnson J, Schurgers LJ, Liu CL, Daemen MJ, Cleutjens KB, Shi GP, Biessen EA, Heeneman S.

PLoS One. 2016 Sep 16;11(9):e0162595. doi: 10.1371/journal.pone.0162595. eCollection 2016.


ADAM17 controls IL-6 signaling by cleavage of the murine IL-6Rα from the cell surface of leukocytes during inflammatory responses.

Yan I, Schwarz J, Lücke K, Schumacher N, Schumacher V, Schmidt S, Rabe B, Saftig P, Donners M, Rose-John S, Mittrücker HW, Chalaris A.

J Leukoc Biol. 2016 May;99(5):749-60. doi: 10.1189/jlb.3A0515-207R. Epub 2015 Nov 11.


Platelet CD40L Modulates Thrombus Growth Via Phosphatidylinositol 3-Kinase β, and Not Via CD40 and IκB Kinase α.

Kuijpers MJ, Mattheij NJ, Cipolla L, van Geffen JP, Lawrence T, Donners MM, Boon L, Lievens D, Torti M, Noels H, Gerdes N, Cosemans JM, Lutgens E, Heemskerk JW.

Arterioscler Thromb Vasc Biol. 2015 Jun;35(6):1374-81. doi: 10.1161/ATVBAHA.114.305127. Epub 2015 Apr 23.


Bone marrow-specific caspase-1/11 deficiency inhibits atherosclerosis development in Ldlr(-/-) mice.

Hendrikx T, Jeurissen ML, van Gorp PJ, Gijbels MJ, Walenbergh SM, Houben T, van Gorp R, Pöttgens CC, Stienstra R, Netea MG, Hofker MH, Donners MM, Shiri-Sverdlov R.

FEBS J. 2015 Jun;282(12):2327-38. doi: 10.1111/febs.13279. Epub 2015 Apr 20. Erratum in: FEBS J. 2016 Jul;283(14 ):2749.


Experimental illumination of natural habitat--an experimental set-up to assess the direct and indirect ecological consequences of artificial light of different spectral composition.

Spoelstra K, van Grunsven RH, Donners M, Gienapp P, Huigens ME, Slaterus R, Berendse F, Visser ME, Veenendaal E.

Philos Trans R Soc Lond B Biol Sci. 2015 May 5;370(1667). pii: 20140129. doi: 10.1098/rstb.2014.0129.


Myeloid A disintegrin and metalloproteinase domain 10 deficiency modulates atherosclerotic plaque composition by shifting the balance from inflammation toward fibrosis.

van der Vorst EP, Jeurissen M, Wolfs IM, Keijbeck A, Theodorou K, Wijnands E, Schurgers L, Weber S, Gijbels MJ, Hamers AA, Dreymueller D, Rose-John S, de Winther MP, Ludwig A, Saftig P, Biessen EA, Donners MM.

Am J Pathol. 2015 Apr;185(4):1145-55. doi: 10.1016/j.ajpath.2014.11.028. Epub 2015 Feb 7.


Reversal of hypoxia in murine atherosclerosis prevents necrotic core expansion by enhancing efferocytosis.

Marsch E, Theelen TL, Demandt JA, Jeurissen M, van Gink M, Verjans R, Janssen A, Cleutjens JP, Meex SJ, Donners MM, Haenen GR, Schalkwijk CG, Dubois LJ, Lambin P, Mallat Z, Gijbels MJ, Heemskerk JW, Fisher EA, Biessen EA, Janssen BJ, Daemen MJ, Sluimer JC.

Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2545-53. doi: 10.1161/ATVBAHA.114.304023. Epub 2014 Sep 25.


Leukocytes require ADAM10 but not ADAM17 for their migration and inflammatory recruitment into the alveolar space.

Pruessmeyer J, Hess FM, Alert H, Groth E, Pasqualon T, Schwarz N, Nyamoya S, Kollert J, van der Vorst E, Donners M, Martin C, Uhlig S, Saftig P, Dreymueller D, Ludwig A.

Blood. 2014 Jun 26;123(26):4077-88. doi: 10.1182/blood-2013-09-511543. Epub 2014 May 15.


Regulation of adult hematopoiesis by the a disintegrin and metalloproteinase 10 (ADAM10).

Weber S, Wetzel S, Prox J, Lehmann T, Schneppenheim J, Donners M, Saftig P.

Biochem Biophys Res Commun. 2013 Dec 13;442(3-4):234-41. doi: 10.1016/j.bbrc.2013.11.020. Epub 2013 Nov 15.


Reprogramming macrophages to an anti-inflammatory phenotype by helminth antigens reduces murine atherosclerosis.

Wolfs IM, Stöger JL, Goossens P, Pöttgens C, Gijbels MJ, Wijnands E, van der Vorst EP, van Gorp P, Beckers L, Engel D, Biessen EA, Kraal G, van Die I, Donners MM, de Winther MP.

FASEB J. 2014 Jan;28(1):288-99. doi: 10.1096/fj.13-235911. Epub 2013 Sep 16.


Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo.

Jetten N, Verbruggen S, Gijbels MJ, Post MJ, De Winther MP, Donners MM.

Angiogenesis. 2014 Jan;17(1):109-18. doi: 10.1007/s10456-013-9381-6. Epub 2013 Sep 8.


Local delivery of polarized macrophages improves reperfusion recovery in a mouse hind limb ischemia model.

Jetten N, Donners MM, Wagenaar A, Cleutjens JP, van Rooijen N, de Winther MP, Post MJ.

PLoS One. 2013 Jul 24;8(7):e68811. doi: 10.1371/journal.pone.0068811. Print 2013.


Cell surface-expressed phosphatidylserine as therapeutic target to enhance phagocytosis of apoptotic cells.

Schutters K, Kusters DH, Chatrou ML, Montero-Melendez T, Donners M, Deckers NM, Krysko DV, Vandenabeele P, Perretti M, Schurgers LJ, Reutelingsperger CP.

Cell Death Differ. 2013 Jan;20(1):49-56. doi: 10.1038/cdd.2012.107. Epub 2012 Sep 7.


A disintegrin and metalloproteases: molecular scissors in angiogenesis, inflammation and atherosclerosis.

van der Vorst EP, Keijbeck AA, de Winther MP, Donners MM.

Atherosclerosis. 2012 Oct;224(2):302-8. doi: 10.1016/j.atherosclerosis.2012.04.023. Epub 2012 May 8. Review.


Hematopoietic miR155 deficiency enhances atherosclerosis and decreases plaque stability in hyperlipidemic mice.

Donners MM, Wolfs IM, Stöger LJ, van der Vorst EP, Pöttgens CC, Heymans S, Schroen B, Gijbels MJ, de Winther MP.

PLoS One. 2012;7(4):e35877. doi: 10.1371/journal.pone.0035877. Epub 2012 Apr 25.


Differentiation factors and cytokines in the atherosclerotic plaque micro-environment as a trigger for macrophage polarisation.

Wolfs IM, Donners MM, de Winther MP.

Thromb Haemost. 2011 Nov;106(5):763-71. doi: 10.1160/TH11-05-0320. Epub 2011 Sep 22. Review.


Feed-forward signaling by membrane-bound ligand receptor circuit: the case of NOTCH DELTA-like 4 ligand in endothelial cells.

Caolo V, van den Akker NM, Verbruggen S, Donners MM, Swennen G, Schulten H, Waltenberger J, Post MJ, Molin DG.

J Biol Chem. 2010 Dec 24;285(52):40681-9. doi: 10.1074/jbc.M110.176065. Epub 2010 Oct 19.


A disintegrin and metalloprotease 10 is a novel mediator of vascular endothelial growth factor-induced endothelial cell function in angiogenesis and is associated with atherosclerosis.

Donners MM, Wolfs IM, Olieslagers S, Mohammadi-Motahhari Z, Tchaikovski V, Heeneman S, van Buul JD, Caolo V, Molin DG, Post MJ, Waltenberger J.

Arterioscler Thromb Vasc Biol. 2010 Nov;30(11):2188-95. doi: 10.1161/ATVBAHA.110.213124. Epub 2010 Sep 2.


The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling.

Donners MM, Beckers L, Lievens D, Munnix I, Heemskerk J, Janssen BJ, Wijnands E, Cleutjens J, Zernecke A, Weber C, Ahonen CL, Benbow U, Newby AC, Noelle RJ, Daemen MJ, Lutgens E.

Blood. 2008 May 1;111(9):4596-604. doi: 10.1182/blood-2007-05-088906. Epub 2008 Jan 14.


CD40 and its ligand in atherosclerosis.

Lutgens E, Lievens D, Beckers L, Donners M, Daemen M.

Trends Cardiovasc Med. 2007 May;17(4):118-23. Review.


Drug-induced immunomodulation to affect the development and progression of atherosclerosis: a new opportunity?

Heeneman S, Donners MM, Bai L, Daemen MJ.

Expert Rev Cardiovasc Ther. 2007 Mar;5(2):345-64. Review.


Low-dose FK506 blocks collar-induced atherosclerotic plaque development and stabilizes plaques in ApoE-/- mice.

Donners MM, Bot I, De Windt LJ, van Berkel TJ, Daemen MJ, Biessen EA, Heeneman S.

Am J Transplant. 2005 Jun;5(6):1204-15.


Proteomic analysis of differential protein expression in human atherosclerotic plaque progression.

Donners MM, Verluyten MJ, Bouwman FG, Mariman EC, Devreese B, Vanrobaeys F, van Beeumen J, van den Akker LH, Daemen MJ, Heeneman S.

J Pathol. 2005 May;206(1):39-45.


Inflammation and restenosis: implications for therapy.

Donners MM, Daemen MJ, Cleutjens KB, Heeneman S.

Ann Med. 2003;35(7):523-31. Review.


Serine protease inhibitor Serp-1 strongly impairs atherosclerotic lesion formation and induces a stable plaque phenotype in ApoE-/-mice.

Bot I, von der Thüsen JH, Donners MM, Lucas A, Fekkes ML, de Jager SC, Kuiper J, Daemen MJ, van Berkel TJ, Heeneman S, Biessen EA.

Circ Res. 2003 Sep 5;93(5):464-71. Epub 2003 Aug 14.


Increased arterial expression of a glycosylated haptoglobin isoform after balloon dilation.

Smeets MB, Sluijter JP, Donners MM, Velema E, Heeneman S, Pasterkamp G, de Kleijn DP.

Cardiovasc Res. 2003 Jun 1;58(3):689-95.


Supplemental Content

Loading ...
Support Center