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Items: 38


The Aminoalkylindole BML-190 Negatively Regulates Chitosan Synthesis via the Cyclic AMP/Protein Kinase A1 Pathway in Cryptococcus neoformans.

Maybruck BT, Lam WC, Specht CA, Ilagan MXG, Donlin MJ, Lodge JK.

mBio. 2019 Dec 17;10(6). pii: e02264-19. doi: 10.1128/mBio.02264-19.


Synthesis and Evaluation of Troponoids as a New Class of Antibiotics.

Cao F, Orth C, Donlin MJ, Adegboyega P, Meyers MJ, Murelli RP, Elagawany M, Elgendy B, Tavis JE.

ACS Omega. 2018 Nov 30;3(11):15125-15133. doi: 10.1021/acsomega.8b01754. Epub 2018 Nov 8.


Cryptococcus neoformans Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis.

Upadhya R, Baker LG, Lam WC, Specht CA, Donlin MJ, Lodge JK.

mBio. 2018 Nov 20;9(6). pii: e02087-18. doi: 10.1128/mBio.02087-18.


A fluorogenic C. neoformans reporter strain with a robust expression of m-cherry expressed from a safe haven site in the genome.

Upadhya R, Lam WC, Maybruck BT, Donlin MJ, Chang AL, Kayode S, Ormerod KL, Fraser JA, Doering TL, Lodge JK.

Fungal Genet Biol. 2017 Nov;108:13-25. doi: 10.1016/j.fgb.2017.08.008. Epub 2017 Sep 12.


Troponoids Can Inhibit Growth of the Human Fungal Pathogen Cryptococcus neoformans.

Donlin MJ, Zunica A, Lipnicky A, Garimallaprabhakaran AK, Berkowitz AJ, Grigoryan A, Meyers MJ, Tavis JE, Murelli RP.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02574-16. doi: 10.1128/AAC.02574-16. Print 2017 Apr.


Hepatitis B virus genetic diversity has minimal impact on sensitivity of the viral ribonuclease H to inhibitors.

Lu G, Villa JA, Donlin MJ, Edwards TC, Cheng X, Heier RF, Meyers MJ, Tavis JE.

Antiviral Res. 2016 Nov;135:24-30. doi: 10.1016/j.antiviral.2016.09.009. Epub 2016 Sep 28.


A Functional Interplay between Human Immunodeficiency Virus Type 1 Protease Residues 77 and 93 Involved in Differential Regulation of Precursor Autoprocessing and Mature Protease Activity.

Counts CJ, Ho PS, Donlin MJ, Tavis JE, Chen C.

PLoS One. 2015 Apr 20;10(4):e0123561. doi: 10.1371/journal.pone.0123561. eCollection 2015.


Checkpoint blockade immunotherapy relies on T-bet but not Eomes to induce effector function in tumor-infiltrating CD8+ T cells.

Berrien-Elliott MM, Yuan J, Swier LE, Jackson SR, Chen CL, Donlin MJ, Teague RM.

Cancer Immunol Res. 2015 Feb;3(2):116-24. doi: 10.1158/2326-6066.CIR-14-0159. Epub 2014 Dec 16.


Cross talk between the cell wall integrity and cyclic AMP/protein kinase A pathways in Cryptococcus neoformans.

Donlin MJ, Upadhya R, Gerik KJ, Lam W, VanArendonk LG, Specht CA, Sharma NK, Lodge JK.

mBio. 2014 Aug 12;5(4). pii: e01573-14. doi: 10.1128/mBio.01573-14.


HCV genome-wide genetic analyses in context of disease progression and hepatocellular carcinoma.

Donlin MJ, Lomonosova E, Kiss A, Cheng X, Cao F, Curto TM, Di Bisceglie A, Tavis JE.

PLoS One. 2014 Jul 31;9(7):e103748. doi: 10.1371/journal.pone.0103748. eCollection 2014.


Inflammation programs self-reactive CD8+ T cells to acquire T-box-mediated effector function but does not prevent deletional tolerance.

Jackson SR, Yuan J, Berrien-Elliott MM, Chen CL, Meyer JM, Donlin MJ, Teague RM.

J Leukoc Biol. 2014 Sep;96(3):397-410. doi: 10.1189/jlb.1A0913-500RR. Epub 2014 May 13.


Cryptococcus at work: gene expression during human infection.

Upadhya R, Donlin MJ, Lodge JK.

mBio. 2014 Apr 22;5(2):e01097. doi: 10.1128/mBio.01097-14.


p38MAPK plays a crucial role in stromal-mediated tumorigenesis.

Alspach E, Flanagan KC, Luo X, Ruhland MK, Huang H, Pazolli E, Donlin MJ, Marsh T, Piwnica-Worms D, Monahan J, Novack DV, McAllister SS, Stewart SA.

Cancer Discov. 2014 Jun;4(6):716-29. doi: 10.1158/2159-8290.CD-13-0743. Epub 2014 Mar 26.


Global transcriptome profile of Cryptococcus neoformans during exposure to hydrogen peroxide induced oxidative stress.

Upadhya R, Campbell LT, Donlin MJ, Aurora R, Lodge JK.

PLoS One. 2013;8(1):e55110. doi: 10.1371/journal.pone.0055110. Epub 2013 Jan 28.


Hepatitis C virus envelope glycoprotein signatures are associated with treatment failure and modulation of viral entry and neutralization.

Schvoerer E, Moenne-Loccoz R, Murray JM, Velay A, Turek M, Fofana I, Fafi-Kremer S, Erba AC, Habersetzer F, Doffoël M, Gut JP, Donlin MJ, Tavis JE, Zeisel MB, Stoll-Keller F, Baumert TF.

J Infect Dis. 2013 Apr 15;207(8):1306-15. doi: 10.1093/infdis/jit032. Epub 2013 Jan 18.


Coordinated evolution among hepatitis C virus genomic sites is coupled to host factors and resistance to interferon.

Lara J, Tavis JE, Donlin MJ, Lee WM, Yuan HJ, Pearlman BL, Vaughan G, Forbi JC, Xia GL, Khudyakov YE.

In Silico Biol. 2011-2012;11(5-6):213-24. doi: 10.3233/ISB-2012-0456.


Genome-wide networks of amino acid covariances are common among viruses.

Donlin MJ, Szeto B, Gohara DW, Aurora R, Tavis JE.

J Virol. 2012 Mar;86(6):3050-63. doi: 10.1128/JVI.06857-11. Epub 2012 Jan 11.


Prospects for personalizing antiviral therapy for hepatitis C virus with pharmacogenetics.

Tavis JE, Donlin MJ, Aurora R, Fan X, Di Bisceglie AM.

Genome Med. 2011 Feb 8;3(2):8. doi: 10.1186/gm222.


Morphine modulation of thrombospondin levels in astrocytes and its implications for neurite outgrowth and synapse formation.

Ikeda H, Miyatake M, Koshikawa N, Ochiai K, Yamada K, Kiss A, Donlin MJ, Panneton WM, Churchill JD, Green M, Siddiqui AM, Leinweber AL, Crews NR, Ezerskiy LA, Rendell VR, Belcheva MM, Coscia CJ.

J Biol Chem. 2010 Dec 3;285(49):38415-27. doi: 10.1074/jbc.M110.109827. Epub 2010 Oct 2.


Genetic and biochemical diversity in the HCV NS5B RNA polymerase in the context of interferon α plus ribavirin therapy.

Cao F, Donlin MJ, Turner K, Cheng X, Tavis JE.

J Viral Hepat. 2011 May;18(5):349-57. doi: 10.1111/j.1365-2893.2010.01316.x.


KRE genes are required for beta-1,6-glucan synthesis, maintenance of capsule architecture and cell wall protein anchoring in Cryptococcus neoformans.

Gilbert NM, Donlin MJ, Gerik KJ, Specht CA, Djordjevic JT, Wilson CF, Sorrell TC, Lodge JK.

Mol Microbiol. 2010 Apr;76(2):517-34. doi: 10.1111/j.1365-2958.2010.07119.x. Epub 2010 Apr 6.


Contribution of genome-wide HCV genetic differences to outcome of interferon-based therapy in Caucasian American and African American patients.

Donlin MJ, Cannon NA, Aurora R, Li J, Wahed AS, Di Bisceglie AM, Tavis JE; Virahep-C Study Group.

PLoS One. 2010 Feb 3;5(2):e9032. doi: 10.1371/journal.pone.0009032.


Using the Generic Genome Browser (GBrowse).

Donlin MJ.

Curr Protoc Bioinformatics. 2009 Dec;Chapter 9:Unit 9.9. doi: 10.1002/0471250953.bi0909s28.


Evidence for action of ribavirin through the hepatitis C virus RNA polymerase.

Cannon NA, Donlin MJ, Mayes LM, Lyra AC, Di Bisceglie AM, Tavis JE.

J Viral Hepat. 2009 Aug;16(8):595-604. doi: 10.1111/j.1365-2893.2009.01109.x. Epub 2009 Feb 23.


Genome-wide hepatitis C virus amino acid covariance networks can predict response to antiviral therapy in humans.

Aurora R, Donlin MJ, Cannon NA, Tavis JE.

J Clin Invest. 2009 Jan;119(1):225-36. doi: 10.1172/JCI37085. Epub 2008 Dec 22.


Hepatitis C virus diversity and evolution in the full open-reading frame during antiviral therapy.

Cannon NA, Donlin MJ, Fan X, Aurora R, Tavis JE; Virahep-C Study Group.

PLoS One. 2008 May 7;3(5):e2123. doi: 10.1371/journal.pone.0002123.


Using the Generic Genome Browser (GBrowse).

Donlin MJ.

Curr Protoc Bioinformatics. 2007 Mar;Chapter 9:Unit 9.9. doi: 10.1002/0471250953.bi0909s17.


Pretreatment sequence diversity differences in the full-length hepatitis C virus open reading frame correlate with early response to therapy.

Donlin MJ, Cannon NA, Yao E, Li J, Wahed A, Taylor MW, Belle SH, Di Bisceglie AM, Aurora R, Tavis JE; Virahep-C Study Group.

J Virol. 2007 Aug;81(15):8211-24. Epub 2007 May 23.


Chitosan, the deacetylated form of chitin, is necessary for cell wall integrity in Cryptococcus neoformans.

Baker LG, Specht CA, Donlin MJ, Lodge JK.

Eukaryot Cell. 2007 May;6(5):855-67. Epub 2007 Mar 30.


Posttranslational, translational, and transcriptional responses to nitric oxide stress in Cryptococcus neoformans: implications for virulence.

Missall TA, Pusateri ME, Donlin MJ, Chambers KT, Corbett JA, Lodge JK.

Eukaryot Cell. 2006 Mar;5(3):518-29.


A chitin synthase and its regulator protein are critical for chitosan production and growth of the fungal pathogen Cryptococcus neoformans.

Banks IR, Specht CA, Donlin MJ, Gerik KJ, Levitz SM, Lodge JK.

Eukaryot Cell. 2005 Nov;4(11):1902-12.


Cell wall integrity is dependent on the PKC1 signal transduction pathway in Cryptococcus neoformans.

Gerik KJ, Donlin MJ, Soto CE, Banks AM, Banks IR, Maligie MA, Selitrennikoff CP, Lodge JK.

Mol Microbiol. 2005 Oct;58(2):393-408.


The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans.

Loftus BJ, Fung E, Roncaglia P, Rowley D, Amedeo P, Bruno D, Vamathevan J, Miranda M, Anderson IJ, Fraser JA, Allen JE, Bosdet IE, Brent MR, Chiu R, Doering TL, Donlin MJ, D'Souza CA, Fox DS, Grinberg V, Fu J, Fukushima M, Haas BJ, Huang JC, Janbon G, Jones SJ, Koo HL, Krzywinski MI, Kwon-Chung JK, Lengeler KB, Maiti R, Marra MA, Marra RE, Mathewson CA, Mitchell TG, Pertea M, Riggs FR, Salzberg SL, Schein JE, Shvartsbeyn A, Shin H, Shumway M, Specht CA, Suh BB, Tenney A, Utterback TR, Wickes BL, Wortman JR, Wye NH, Kronstad JW, Lodge JK, Heitman J, Davis RW, Fraser CM, Hyman RW.

Science. 2005 Feb 25;307(5713):1321-4. Epub 2005 Jan 13.


Effectiveness of individually tailored calendars in promoting childhood immunization in urban public health centers.

Kreuter MW, Caburnay CA, Chen JJ, Donlin MJ.

Am J Public Health. 2004 Jan;94(1):122-7.


Disseminating effective health promotion programs from prevention research to community organizations.

Caburnay CA, Kreuter MW, Donlin MJ.

J Public Health Manag Pract. 2001 Mar;7(2):81-9.


Mutants affecting nucleotide recognition by T7 DNA polymerase.

Donlin MJ, Johnson KA.

Biochemistry. 1994 Dec 13;33(49):14908-17.


Kinetic partitioning between the exonuclease and polymerase sites in DNA error correction.

Donlin MJ, Patel SS, Johnson KA.

Biochemistry. 1991 Jan 15;30(2):538-46.


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