Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 139


Systematic analysis reveals the prevalence and principles of bypassable gene essentiality.

Li J, Wang HT, Wang WT, Zhang XR, Suo F, Ren JY, Bi Y, Xue YX, Hu W, Dong MQ, Du LL.

Nat Commun. 2019 Mar 1;10(1):1002. doi: 10.1038/s41467-019-08928-1.


DAF-16 stabilizes the aging transcriptome and is activated in mid-aged Caenorhabditis elegans to cope with internal stress.

Li ST, Zhao HQ, Zhang P, Liang CY, Zhang YP, Hsu AL, Dong MQ.

Aging Cell. 2019 Feb 17:e12896. doi: 10.1111/acel.12896. [Epub ahead of print]


The USTC co-opts an ancient machinery to drive piRNA transcription in C. elegans.

Weng C, Kosalka J, Berkyurek AC, Stempor P, Feng X, Mao H, Zeng C, Li WJ, Yan YH, Dong MQ, Morero NR, Zuliani C, Barabas O, Ahringer J, Guang S, Miska EA.

Genes Dev. 2019 Jan 1;33(1-2):90-102. doi: 10.1101/gad.319293.118. Epub 2018 Dec 19.


Author Correction: Cryo-EM structure of the exocyst complex.

Mei K, Li Y, Wang S, Shao G, Wang J, Ding Y, Luo G, Yue P, Liu JJ, Wang X, Dong MQ, Wang HW, Guo W.

Nat Struct Mol Biol. 2018 Dec;25(12):1137. doi: 10.1038/s41594-018-0157-y.


Comprehensive identification of peptides in tandem mass spectra using an efficient open search engine.

Chi H, Liu C, Yang H, Zeng WF, Wu L, Zhou WJ, Wang RM, Niu XN, Ding YH, Zhang Y, Wang ZW, Chen ZL, Sun RX, Liu T, Tan GM, Dong MQ, Xu P, Zhang PH, He SM.

Nat Biotechnol. 2018 Oct 8. doi: 10.1038/nbt.4236. [Epub ahead of print]


Connective tissue growth factor (CCN2) is a matricellular preproprotein controlled by proteolytic activation.

Kaasbøll OJ, Gadicherla AK, Wang JH, Monsen VT, Hagelin EMV, Dong MQ, Attramadal H.

J Biol Chem. 2018 Nov 16;293(46):17953-17970. doi: 10.1074/jbc.RA118.004559. Epub 2018 Sep 27.


CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature.

Louveau A, Herz J, Alme MN, Salvador AF, Dong MQ, Viar KE, Herod SG, Knopp J, Setliff JC, Lupi AL, Da Mesquita S, Frost EL, Gaultier A, Harris TH, Cao R, Hu S, Lukens JR, Smirnov I, Overall CC, Oliver G, Kipnis J.

Nat Neurosci. 2018 Oct;21(10):1380-1391. doi: 10.1038/s41593-018-0227-9. Epub 2018 Sep 17.


Author Correction: Structure and mechanogating mechanism of the Piezo1 channel.

Zhao Q, Zhou H, Chi S, Wang Y, Wang J, Geng J, Wu K, Liu W, Zhang T, Dong MQ, Wang J, Li X, Xiao B.

Nature. 2018 Nov;563(7730):E19. doi: 10.1038/s41586-018-0513-4.


Mapping disulfide bonds from sub-micrograms of purified proteins or micrograms of complex protein mixtures.

Lu S, Cao Y, Fan SB, Chen ZL, Fang RQ, He SM, Dong MQ.

Biophys Rep. 2018;4(2):68-81. doi: 10.1007/s41048-018-0050-6. Epub 2018 Apr 23.


Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate.

Zhou D, Zhu X, Zheng S, Tan D, Dong MQ, Ye K.

Protein Cell. 2019 Feb;10(2):120-130. doi: 10.1007/s13238-018-0526-7. Epub 2018 Mar 19.


Structure and mechanogating mechanism of the Piezo1 channel.

Zhao Q, Zhou H, Chi S, Wang Y, Wang J, Geng J, Wu K, Liu W, Zhang T, Dong MQ, Wang J, Li X, Xiao B.

Nature. 2018 Feb 22;554(7693):487-492. doi: 10.1038/nature25743. Epub 2018 Jan 22. Erratum in: Nature. 2018 Nov;563(7730):E19.


Molecular Architecture of the Essential Yeast Histone Acetyltransferase Complex NuA4 Redefines Its Multimodularity.

Setiaputra D, Ahmad S, Dalwadi U, Steunou AL, Lu S, Ross JD, Dong MQ, Côté J, Yip CK.

Mol Cell Biol. 2018 Apr 16;38(9). pii: e00570-17. doi: 10.1128/MCB.00570-17. Print 2018 May 1.


Cryo-EM structure of the exocyst complex.

Mei K, Li Y, Wang S, Shao G, Wang J, Ding Y, Luo G, Yue P, Liu JJ, Wang X, Dong MQ, Wang HW, Guo W.

Nat Struct Mol Biol. 2018 Feb;25(2):139-146. doi: 10.1038/s41594-017-0016-2. Epub 2018 Jan 15. Erratum in: Nat Struct Mol Biol. 2018 Dec;25(12):1137.


Spontaneous and specific chemical cross-linking in live cells to capture and identify protein interactions.

Yang B, Tang S, Ma C, Li ST, Shao GC, Dang B, DeGrado WF, Dong MQ, Wang PG, Ding S, Wang L.

Nat Commun. 2017 Dec 21;8(1):2240. doi: 10.1038/s41467-017-02409-z.


Chk1 modulates the interaction between myosin phosphatase targeting protein 1 (MYPT1) and protein phosphatase 1cβ (PP1cβ).

Hu X, Li Z, Ding Y, Geng Q, Xiahou Z, Ru H, Dong MQ, Xu X, Li J.

Cell Cycle. 2018;17(4):421-427. doi: 10.1080/15384101.2017.1418235. Epub 2018 Mar 19.


Carboxylate-Selective Chemical Cross-Linkers for Mass Spectrometric Analysis of Protein Structures.

Zhang X, Wang JH, Tan D, Li Q, Li M, Gong Z, Tang C, Liu Z, Dong MQ, Lei X.

Anal Chem. 2018 Jan 16;90(2):1195-1201. doi: 10.1021/acs.analchem.7b03789. Epub 2018 Jan 4.


Protocol for analyzing protein ensemble structures from chemical cross-links using DynaXL.

Gong Z, Liu Z, Dong X, Ding YH, Dong MQ, Tang C.

Biophys Rep. 2017;3(4):100-108. doi: 10.1007/s41048-017-0044-9. Epub 2017 Nov 20.


Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis.

Ma X, Liu H, Li J, Wang Y, Ding YH, Shen H, Yang Y, Sun C, Huang M, Tu Y, Liu Y, Zhao Y, Dong MQ, Xu P, Tang TS, Guo C.

Nat Commun. 2017 Dec 5;8(1):1941. doi: 10.1038/s41467-017-02164-1.


Analysis of the Expression of Angioarchitecture-related Factors in Patients with Cerebral Arteriovenous Malformation.

Chen GZ, Ke Y, Qin K, Dong MQ, Zeng SJ, Lin XF, Zhan SQ, Tang K, Peng C, Ding XW, Zhou D.

Chin Med J (Engl). 2017 Oct 20;130(20):2465-2472. doi: 10.4103/0366-6999.216413.


Conserved and unique features of the fission yeast core Atg1 complex.

Nanji T, Liu X, Chew LH, Li FK, Biswas M, Yu ZQ, Lu S, Dong MQ, Du LL, Klionsky DJ, Yip CK.

Autophagy. 2017;13(12):2018-2027. doi: 10.1080/15548627.2017.1382782. Epub 2017 Nov 23.


Characterizing Protein Dynamics with Integrative Use of Bulk and Single-Molecule Techniques.

Liu Z, Gong Z, Cao Y, Ding YH, Dong MQ, Lu YB, Zhang WP, Tang C.

Biochemistry. 2018 Jan 23;57(3):305-313. doi: 10.1021/acs.biochem.7b00817. Epub 2017 Oct 2.


Segmentation and classification of two-channel C. elegans nucleus-labeled fluorescence images.

Zhao M, An J, Li H, Zhang J, Li ST, Li XM, Dong MQ, Mao H, Tao L.

BMC Bioinformatics. 2017 Sep 15;18(1):412. doi: 10.1186/s12859-017-1817-3.


pGlyco 2.0 enables precision N-glycoproteomics with comprehensive quality control and one-step mass spectrometry for intact glycopeptide identification.

Liu MQ, Zeng WF, Fang P, Cao WQ, Liu C, Yan GQ, Zhang Y, Peng C, Wu JQ, Zhang XJ, Tu HJ, Chi H, Sun RX, Cao Y, Dong MQ, Jiang BY, Huang JM, Shen HL, Wong CCL, He SM, Yang PY.

Nat Commun. 2017 Sep 5;8(1):438. doi: 10.1038/s41467-017-00535-2.


Polo-like kinase 1 (PLK1)-dependent phosphorylation of methylenetetrahydrofolate reductase (MTHFR) regulates replication via histone methylation.

Li X, Nai S, Ding Y, Geng Q, Zhu B, Yu K, Zhu WG, Dong MQ, Su XD, Xu X, Li J.

Cell Cycle. 2017 Oct 18;16(20):1933-1942. doi: 10.1080/15384101.2017.1363942. Epub 2017 Aug 18.


Architecture of the ATG2B-WDR45 complex and an aromatic Y/HF motif crucial for complex formation.

Zheng JX, Li Y, Ding YH, Liu JJ, Zhang MJ, Dong MQ, Wang HW, Yu L.

Autophagy. 2017;13(11):1870-1883. doi: 10.1080/15548627.2017.1359381. Epub 2017 Sep 13.


Automatic regulation of NF-κB by pHSP70/IκBαm to prevent acute lung injury in mice.

Dong HY, Cui Y, Zhang B, Luo Y, Wang YX, Dong MQ, Liu ML, Zhao PT, Niu W, Li ZC.

Arch Biochem Biophys. 2017 Nov 15;634:47-56. doi: 10.1016/ Epub 2017 Aug 2.


Cryo-EM structure and biochemical analysis reveal the basis of the functional difference between human PI3KC3-C1 and -C2.

Ma M, Liu JJ, Li Y, Huang Y, Ta N, Chen Y, Fu H, Ye MD, Ding Y, Huang W, Wang J, Dong MQ, Yu L, Wang HW.

Cell Res. 2017 Aug;27(8):989-1001. doi: 10.1038/cr.2017.94. Epub 2017 Jul 21.


Correction: Molecular architecture of the 90S small subunit pre-ribosome.

Sun Q, Zhu X, Qi J, An W, Lan P, Tan D, Chen R, Wang B, Zheng S, Zhang C, Chen X, Zhang W, Chen J, Dong MQ, Ye K.

Elife. 2017 Jun 26;6. pii: e29876. doi: 10.7554/eLife.29876. No abstract available.


Reoxygenation Reverses Hypoxic Pulmonary Arterial Remodeling by Inducing Smooth Muscle Cell Apoptosis via Reactive Oxygen Species-Mediated Mitochondrial Dysfunction.

Chen J, Wang YX, Dong MQ, Zhang B, Luo Y, Niu W, Li ZC.

J Am Heart Assoc. 2017 Jun 23;6(6). pii: e005602. doi: 10.1161/JAHA.117.005602.


SUMO-Targeted DNA Translocase Rrp2 Protects the Genome from Top2-Induced DNA Damage.

Wei Y, Diao LX, Lu S, Wang HT, Suo F, Dong MQ, Du LL.

Mol Cell. 2017 Jun 1;66(5):581-596.e6. doi: 10.1016/j.molcel.2017.04.017. Epub 2017 May 25.


Dynein-Driven Retrograde Intraflagellar Transport Is Triphasic in C. elegans Sensory Cilia.

Yi P, Li WJ, Dong MQ, Ou G.

Curr Biol. 2017 May 22;27(10):1448-1461.e7. doi: 10.1016/j.cub.2017.04.015. Epub 2017 May 4.


Myrf ER-Bound Transcription Factors Drive C. elegans Synaptic Plasticity via Cleavage-Dependent Nuclear Translocation.

Meng J, Ma X, Tao H, Jin X, Witvliet D, Mitchell J, Zhu M, Dong MQ, Zhen M, Jin Y, Qi YB.

Dev Cell. 2017 Apr 24;41(2):180-194.e7. doi: 10.1016/j.devcel.2017.03.022.


Spectraplakin Induces Positive Feedback between Fusogens and the Actin Cytoskeleton to Promote Cell-Cell Fusion.

Yang Y, Zhang Y, Li WJ, Jiang Y, Zhu Z, Hu H, Li W, Wu JW, Wang ZX, Dong MQ, Huang S, Ou G.

Dev Cell. 2017 Apr 10;41(1):107-120.e4. doi: 10.1016/j.devcel.2017.03.006.


Structural Insights of WHAMM's Interaction with Microtubules by Cryo-EM.

Liu T, Dai A, Cao Y, Zhang R, Dong MQ, Wang HW.

J Mol Biol. 2017 May 5;429(9):1352-1363. doi: 10.1016/j.jmb.2017.03.022. Epub 2017 Mar 25.


Phosphorylation of LSD1 by PLK1 promotes its chromatin release during mitosis.

Peng B, Shi R, Jiang W, Ding YH, Dong MQ, Zhu WG, Xu X.

Cell Biosci. 2017 Mar 23;7:15. doi: 10.1186/s13578-017-0142-x. eCollection 2017.


Molecular architecture of the 90S small subunit pre-ribosome.

Sun Q, Zhu X, Qi J, An W, Lan P, Tan D, Chen R, Wang B, Zheng S, Zhang C, Chen X, Zhang W, Chen J, Dong MQ, Ye K.

Elife. 2017 Feb 28;6. pii: e22086. doi: 10.7554/eLife.22086. Erratum in: Elife. 2017 Jun 26;6:.


Hippo kinases maintain polarity during directional cell migration in Caenorhabditis elegans.

Feng G, Zhu Z, Li WJ, Lin Q, Chai Y, Dong MQ, Ou G.

EMBO J. 2017 Feb 1;36(3):334-345. doi: 10.15252/embj.201695734. Epub 2016 Dec 23.


Modeling Protein Excited-state Structures from "Over-length" Chemical Cross-links.

Ding YH, Gong Z, Dong X, Liu K, Liu Z, Liu C, He SM, Dong MQ, Tang C.

J Biol Chem. 2017 Jan 27;292(4):1187-1196. doi: 10.1074/jbc.M116.761841. Epub 2016 Dec 19.


4.4 Å Resolution Cryo-EM structure of human mTOR Complex 1.

Yang H, Wang J, Liu M, Chen X, Huang M, Tan D, Dong MQ, Wong CC, Wang J, Xu Y, Wang HW.

Protein Cell. 2016 Dec;7(12):878-887. doi: 10.1007/s13238-016-0346-6. Epub 2016 Dec 1.


N-terminal acetylation promotes synaptonemal complex assembly in C. elegans.

Gao J, Barroso C, Zhang P, Kim HM, Li S, Labrador L, Lightfoot J, Gerashchenko MV, Labunskyy VM, Dong MQ, Martinez-Perez E, Colaiácovo MP.

Genes Dev. 2016 Nov 1;30(21):2404-2416. Epub 2016 Nov 14.


Molecular architecture of the yeast Elongator complex reveals an unexpected asymmetric subunit arrangement.

Setiaputra DT, Cheng DT, Lu S, Hansen JM, Dalwadi U, Lam CH, To JL, Dong MQ, Yip CK.

EMBO Rep. 2017 Feb;18(2):280-291. doi: 10.15252/embr.201642548. Epub 2016 Nov 21.


Atg20- and Atg24-family proteins promote organelle autophagy in fission yeast.

Zhao D, Liu XM, Yu ZQ, Sun LL, Xiong X, Dong MQ, Du LL.

J Cell Sci. 2016 Nov 15;129(22):4289-4304. Epub 2016 Oct 13.


Quantitative Proteomics of Sleep-Deprived Mouse Brains Reveals Global Changes in Mitochondrial Proteins.

Ren J, Zhang MJ, Li TM, Zhang JE, Lin R, Chen S, Luo M, Dong MQ.

PLoS One. 2016 Sep 29;11(9):e0163500. doi: 10.1371/journal.pone.0163500. eCollection 2016.


Atomic modeling of the ITS2 ribosome assembly subcomplex from cryo-EM together with mass spectrometry-identified protein-protein crosslinks.

Wu S, Tan D, Woolford JL Jr, Dong MQ, Gao N.

Protein Sci. 2017 Jan;26(1):103-112. doi: 10.1002/pro.3045. Epub 2016 Oct 13.


Correction: Serum- and Glucocorticoid-Inducible Kinase-1 (SGK-1) Plays a Role in Membrane Trafficking in Caenorhabditis elegans.

Zhu M, Wu G, Li YX, Stevens JK, Fan CX, Spang A, Dong MQ.

PLoS One. 2016 Sep 15;11(9):e0163398. doi: 10.1371/journal.pone.0163398. eCollection 2016.


Structural characterization of coatomer in its cytosolic state.

Wang S, Zhai Y, Pang X, Niu T, Ding YH, Dong MQ, Hsu VW, Sun Z, Sun F.

Protein Cell. 2016 Aug;7(8):586-600. doi: 10.1007/s13238-016-0296-z. Epub 2016 Jul 29.


Diverse roles of assembly factors revealed by structures of late nuclear pre-60S ribosomes.

Wu S, Tutuncuoglu B, Yan K, Brown H, Zhang Y, Tan D, Gamalinda M, Yuan Y, Li Z, Jakovljevic J, Ma C, Lei J, Dong MQ, Woolford JL Jr, Gao N.

Nature. 2016 Jun 2;534(7605):133-7. doi: 10.1038/nature17942. Epub 2016 May 25.


CryoEM structure of yeast cytoplasmic exosome complex.

Liu JJ, Niu CY, Wu Y, Tan D, Wang Y, Ye MD, Liu Y, Zhao W, Zhou K, Liu QS, Dai J, Yang X, Dong MQ, Huang N, Wang HW.

Cell Res. 2016 Jul;26(7):822-37. doi: 10.1038/cr.2016.56. Epub 2016 May 13.


O-GlcNAcylation Antagonizes Phosphorylation of CDH1 (CDC20 Homologue 1).

Tian J, Geng Q, Ding Y, Liao J, Dong MQ, Xu X, Li J.

J Biol Chem. 2016 Jun 3;291(23):12136-44. doi: 10.1074/jbc.M116.717850. Epub 2016 Apr 14.


Increasing the Depth of Mass-Spectrometry-Based Structural Analysis of Protein Complexes through the Use of Multiple Cross-Linkers.

Ding YH, Fan SB, Li S, Feng BY, Gao N, Ye K, He SM, Dong MQ.

Anal Chem. 2016 Apr 19;88(8):4461-9. doi: 10.1021/acs.analchem.6b00281. Epub 2016 Apr 4.


Supplemental Content

Support Center