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Items: 1 to 50 of 114

1.

CK2 modulates adipocyte insulin-signaling and is up-regulated in human obesity.

Borgo C, Milan G, Favaretto F, Stasi F, Fabris R, Salizzato V, Cesaro L, Belligoli A, Sanna M, Foletto M, Prevedello L, Vindigni V, Bardini R, Donella-Deana A, Vettor R.

Sci Rep. 2017 Dec 14;7(1):17569. doi: 10.1038/s41598-017-17809-w.

2.

Generation and quantitative proteomics analysis of CK2α/α'(-/-) cells.

Borgo C, Franchin C, Scalco S, Bosello-Travain V, Donella-Deana A, Arrigoni G, Salvi M, Pinna LA.

Sci Rep. 2017 Feb 17;7:42409. doi: 10.1038/srep42409.

3.

Inhibition of protein kinase CK2 by CX-5011 counteracts imatinib-resistance preventing rpS6 phosphorylation in chronic myeloid leukaemia cells: new combined therapeutic strategies.

Salizzato V, Borgo C, Cesaro L, Pinna LA, Donella-Deana A.

Oncotarget. 2016 Apr 5;7(14):18204-18. doi: 10.18632/oncotarget.7569.

4.

Protein kinase CK2 potentiates translation efficiency by phosphorylating eIF3j at Ser127.

Borgo C, Franchin C, Salizzato V, Cesaro L, Arrigoni G, Matricardi L, Pinna LA, Donella-Deana A.

Biochim Biophys Acta. 2015 Jul;1853(7):1693-701. doi: 10.1016/j.bbamcr.2015.04.004. Epub 2015 Apr 15.

5.

A "SYDE" effect of hierarchical phosphorylation: possible relevance to the cystic fibrosis basic defect.

Venerando A, Cesaro L, Marin O, Donella-Deana A, Pinna LA.

Cell Mol Life Sci. 2014 Jun;71(12):2193-6. doi: 10.1007/s00018-014-1581-8. Epub 2014 Feb 25.

PMID:
24566881
6.

Phosphorylation of cystic fibrosis transmembrane conductance regulator (CFTR) serine-511 by the combined action of tyrosine kinases and CK2: the implication of tyrosine-512 and phenylalanine-508.

Cesaro L, Marin O, Venerando A, Donella-Deana A, Pinna LA.

Amino Acids. 2013 Dec;45(6):1423-9. doi: 10.1007/s00726-013-1613-y. Epub 2013 Nov 1.

PMID:
24178769
7.

Aberrant signalling by protein kinase CK2 in imatinib-resistant chronic myeloid leukaemia cells: biochemical evidence and therapeutic perspectives.

Borgo C, Cesaro L, Salizzato V, Ruzzene M, Massimino ML, Pinna LA, Donella-Deana A.

Mol Oncol. 2013 Dec;7(6):1103-15. doi: 10.1016/j.molonc.2013.08.006. Epub 2013 Aug 22.

8.

Effects of the CK2 inhibitors CX-4945 and CX-5011 on drug-resistant cells.

Zanin S, Borgo C, Girardi C, O'Brien SE, Miyata Y, Pinna LA, Donella-Deana A, Ruzzene M.

PLoS One. 2012;7(11):e49193. doi: 10.1371/journal.pone.0049193. Epub 2012 Nov 8.

9.

Inhibition of protein kinase CK2 by flavonoids and tyrphostins. A structural insight.

Lolli G, Cozza G, Mazzorana M, Tibaldi E, Cesaro L, Donella-Deana A, Meggio F, Venerando A, Franchin C, Sarno S, Battistutta R, Pinna LA.

Biochemistry. 2012 Aug 7;51(31):6097-107. Epub 2012 Jul 25.

PMID:
22794353
10.

Regulation of serotonin transport in human platelets by tyrosine kinase Syk.

Pavanetto M, Zarpellon A, Borgo C, Donella-Deana A, Deana R.

Cell Physiol Biochem. 2011;27(2):139-48. doi: 10.1159/000325216. Epub 2011 Feb 11.

11.

The SH3 domain of HS1 protein recognizes lysine-rich polyproline motifs.

Siligardi G, Ruzza P, Hussain R, Cesaro L, Brunati AM, Pinna LA, Donella-Deana A.

Amino Acids. 2012 Apr;42(4):1361-70. doi: 10.1007/s00726-011-0831-4. Epub 2011 Feb 2.

PMID:
21287358
12.

Src tyrosine kinase preactivation is associated with platelet hypersensitivity in essential thrombocythemia and polycythemia vera.

Randi ML, Brunati AM, Scapin M, Frasson M, Deana R, Magrin E, Fabris F, Donella-Deana A.

Blood. 2010 Jan 21;115(3):667-76. doi: 10.1182/blood-2008-12-196535. Epub 2009 Nov 12.

13.

Recognition of lysine-rich peptide ligands by murine cortactin SH3 domain: CD, ITC, and NMR studies.

Rubini C, Ruzza P, Spaller MR, Siligardi G, Hussain R, Udugamasooriya DG, Bellanda M, Mammi S, Borgogno A, Calderan A, Cesaro L, Brunati AM, Donella-Deana A.

Biopolymers. 2010;94(3):298-306. doi: 10.1002/bip.21350.

PMID:
19921743
14.

Effect of 4-fluoro-L-proline on the SH3 binding affinity.

Ruzza P, Rubini C, Siligardi G, Hussain R, Calderan A, Guiotto A, Cesaro L, Brunati AM, Donella-Deana A.

Adv Exp Med Biol. 2009;611:499-500. No abstract available.

PMID:
19400283
15.

Introduction of N-alkyl residues in proline-rich peptides: effect on SH3 binding affinity and peptide conformation.

Ruzza P, Rubini C, Siligardi G, Hussain R, Calderan A, Guiotto A, Cesaro L, Brunati AM, Donella-Deana A.

Adv Exp Med Biol. 2009;611:65-6. No abstract available.

PMID:
19400095
16.

Grp94 is Tyr-phosphorylated by Fyn in the lumen of the endoplasmic reticulum and translocates to Golgi in differentiating myoblasts.

Frasson M, Vitadello M, Brunati AM, La Rocca N, Tibaldi E, Pinna LA, Gorza L, Donella-Deana A.

Biochim Biophys Acta. 2009 Feb;1793(2):239-52. doi: 10.1016/j.bbamcr.2008.10.001. Epub 2008 Oct 22.

17.

Geldanamycin-induced Lyn dissociation from aberrant Hsp90-stabilized cytosolic complex is an early event in apoptotic mechanisms in B-chronic lymphocytic leukemia.

Trentin L, Frasson M, Donella-Deana A, Frezzato F, Pagano MA, Tibaldi E, Gattazzo C, Zambello R, Semenzato G, Brunati AM.

Blood. 2008 Dec 1;112(12):4665-74. doi: 10.1182/blood-2008-02-139139. Epub 2008 Sep 2.

18.

Protein kinase CK2 catalyzes tyrosine phosphorylation in mammalian cells.

Vilk G, Weber JE, Turowec JP, Duncan JS, Wu C, Derksen DR, Zien P, Sarno S, Donella-Deana A, Lajoie G, Pinna LA, Li SS, Litchfield DW.

Cell Signal. 2008 Nov;20(11):1942-51. doi: 10.1016/j.cellsig.2008.07.002. Epub 2008 Jul 6.

PMID:
18662771
19.

Characterization of compound 584, an Abl kinase inhibitor with lasting effects.

Puttini M, Redaelli S, Moretti L, Brussolo S, Gunby RH, Mologni L, Marchesi E, Cleris L, Donella-Deana A, Drueckes P, Sala E, Lucchini V, Kubbutat M, Formelli F, Zambon A, Scapozza L, Gambacorti-Passerini C.

Haematologica. 2008 May;93(5):653-61. doi: 10.3324/haematol.12212. Epub 2008 Mar 26.

20.

Serotonin (5-HT) transport in human platelets is modulated by Src-catalysed Tyr-phosphorylation of the plasma membrane transporter SERT.

Zarpellon A, Donella-Deana A, Folda A, Turetta L, Pavanetto M, Deana R.

Cell Physiol Biochem. 2008;21(1-3):87-94. doi: 10.1159/000113750. Epub 2008 Jan 16.

21.

A mechanistic design principle for protein tyrosine kinase sensors: application to a validated cancer target.

Wakata A, Cahill SM, Blumenstein M, Gunby RH, Jockusch S, Marti AA, Cimbro B, Gambacorti-Passerini C, Donella-Deana A, Pinna LA, Turro NJ, Lawrence DS.

Org Lett. 2008 Jan 17;10(2):301-4. Epub 2007 Dec 18.

22.

Characterization of some molecular mechanisms governing autoactivation of the catalytic domain of the anaplastic lymphoma kinase.

Tartari CJ, Gunby RH, Coluccia AM, Sottocornola R, Cimbro B, Scapozza L, Donella-Deana A, Pinna LA, Gambacorti-Passerini C.

J Biol Chem. 2008 Feb 15;283(7):3743-50. Epub 2007 Dec 10.

23.

NPM/ALK binds and phosphorylates the RNA/DNA-binding protein PSF in anaplastic large-cell lymphoma.

Galietta A, Gunby RH, Redaelli S, Stano P, Carniti C, Bachi A, Tucker PW, Tartari CJ, Huang CJ, Colombo E, Pulford K, Puttini M, Piazza RG, Ruchatz H, Villa A, Donella-Deana A, Marin O, Perrotti D, Gambacorti-Passerini C.

Blood. 2007 Oct 1;110(7):2600-9. Epub 2007 May 30.

24.

In vitro and in vivo activity of SKI-606, a novel Src-Abl inhibitor, against imatinib-resistant Bcr-Abl+ neoplastic cells.

Puttini M, Coluccia AM, Boschelli F, Cleris L, Marchesi E, Donella-Deana A, Ahmed S, Redaelli S, Piazza R, Magistroni V, Andreoni F, Scapozza L, Formelli F, Gambacorti-Passerini C.

Cancer Res. 2006 Dec 1;66(23):11314-22. Epub 2006 Nov 17.

25.

Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application.

Cozza G, Bonvini P, Zorzi E, Poletto G, Pagano MA, Sarno S, Donella-Deana A, Zagotto G, Rosolen A, Pinna LA, Meggio F, Moro S.

J Med Chem. 2006 Apr 20;49(8):2363-6.

PMID:
16610779
26.

Spatial conformation and topography of the tyrosine aromatic ring in substrate recognition by protein tyrosine kinases.

Ruzza P, Cesaro L, Tourwé D, Calderan A, Biondi B, Maes V, Menegazzo I, Osler A, Rubini C, Guiotto A, Pinna LA, Borin G, Donella-Deana A.

J Med Chem. 2006 Mar 23;49(6):1916-24.

PMID:
16539378
27.

4-Fluoroproline derivative peptides: effect on PPII conformation and SH3 affinity.

Ruzza P, Siligardi G, Donella-Deana A, Calderan A, Hussain R, Rubini C, Cesaro L, Osler A, Guiotto A, Pinna LA, Borin G.

J Pept Sci. 2006 Jul;12(7):462-71.

PMID:
16506148
28.

The N-terminal 11 amino acids of human erythrocyte band 3 are critical for aldolase binding and protein phosphorylation: implications for band 3 function.

Perrotta S, Borriello A, Scaloni A, De Franceschi L, Brunati AM, Turrini F, Nigro V, del Giudice EM, Nobili B, Conte ML, Rossi F, Iolascon A, Donella-Deana A, Zappia V, Poggi V, Anong W, Low P, Mohandas N, Della Ragione F.

Blood. 2005 Dec 15;106(13):4359-66. Epub 2005 Aug 23.

29.

An enzyme-linked immunosorbent assay to screen for inhibitors of the oncogenic anaplastic lymphoma kinase.

Gunby RH, Tartari CJ, Porchia F, Donella-Deana A, Scapozza L, Gambacorti-Passerini C.

Haematologica. 2005 Jul;90(7):988-90.

30.

Unique substrate specificity of anaplastic lymphoma kinase (ALK): development of phosphoacceptor peptides for the assay of ALK activity.

Donella-Deana A, Marin O, Cesaro L, Gunby RH, Ferrarese A, Coluccia AM, Tartari CJ, Mologni L, Scapozza L, Gambacorti-Passerini C, Pinna LA.

Biochemistry. 2005 Jun 14;44(23):8533-42.

PMID:
15938644
31.

Expression, purification, and inhibition of human RET tyrosine kinase.

Mologni L, Sala E, Riva B, Cesaro L, Cazzaniga S, Redaelli S, Marin O, Pasquato N, Donella-Deana A, Gambacorti-Passerini C.

Protein Expr Purif. 2005 May;41(1):177-85.

PMID:
15802236
32.

Thrombin-induced tyrosine phosphorylation of HS1 in human platelets is sequentially catalyzed by Syk and Lyn tyrosine kinases and associated with the cellular migration of the protein.

Brunati AM, Deana R, Folda A, Massimino ML, Marin O, Ledro S, Pinna LA, Donella-Deana A.

J Biol Chem. 2005 Jun 3;280(22):21029-35. Epub 2005 Mar 28.

33.

Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis.

Contri A, Brunati AM, Trentin L, Cabrelle A, Miorin M, Cesaro L, Pinna LA, Zambello R, Semenzato G, Donella-Deana A.

J Clin Invest. 2005 Feb;115(2):369-78.

34.
35.

Characterisation of the serotonin efflux induced by cytosolic Ca2+ and Na+ concentration increase in human platelets.

Turetta L, Donella-Deana A, Folda A, Bulato C, Deana R.

Cell Physiol Biochem. 2004;14(4-6):377-86.

PMID:
15510373
36.

Hyperforin inhibits cancer invasion and metastasis.

Donà M, Dell'Aica I, Pezzato E, Sartor L, Calabrese F, Della Barbera M, Donella-Deana A, Appendino G, Borsarini A, Caniato R, Garbisa S.

Cancer Res. 2004 Sep 1;64(17):6225-32.

37.

Monitoring of PP2A and PP2C by phosphothreonyl peptide substrates.

Donella-Deana A, Boschetti M, Pinna LA.

Methods Enzymol. 2003;366:3-17. No abstract available.

PMID:
14674235
38.

Conformational constraints of tyrosine in protein tyrosine kinase substrates: Information about preferred bioactive side-chain orientation.

Ruzza P, Calderan A, Donella-Deana A, Biondi B, Cesaro L, Osler A, Elardo S, Guiotto A, Pinna LA, Borin G.

Biopolymers. 2003;71(4):478-88.

PMID:
14517899
39.

Green tea epigallocatechin-3-gallate inhibits platelet signalling pathways triggered by both proteolytic and non-proteolytic agonists.

Deana R, Turetta L, Donella-Deana A, Donà M, Brunati AM, De Michiel L, Garbisa S.

Thromb Haemost. 2003 May;89(5):866-74.

PMID:
12719785
40.

Tyrosine phosphorylation of protein kinase CK2 by Src-related tyrosine kinases correlates with increased catalytic activity.

Donella-Deana A, Cesaro L, Sarno S, Ruzzene M, Brunati AM, Marin O, Vilk G, Doherty-Kirby A, Lajoie G, Litchfield DW, Pinna LA.

Biochem J. 2003 Jun 15;372(Pt 3):841-9.

41.

Specific monitoring of Syk protein kinase activity by peptide substrates including constrained analogs of tyrosine.

Donella-Deana A, Ruzza P, Cesaro L, Brunati AM, Calderan A, Borin G, Pinna LA.

FEBS Lett. 2002 Jul 17;523(1-3):48-52.

42.

Band 3 is an anchor protein and a target for SHP-2 tyrosine phosphatase in human erythrocytes.

Bordin L, Brunati AM, Donella-Deana A, Baggio B, Toninello A, Clari G.

Blood. 2002 Jul 1;100(1):276-82.

43.

Antennapedia/HS1 chimeric phosphotyrosyl peptide: conformational properties, binding capability to c-Fgr SH2 domain and cell permeability.

Ruzza P, Donella-Deana A, Calderan A, Brunati A, Massimino ML, Elardo S, Mattiazzo A, Pinna LA, Borin G.

Biopolymers. 2001;60(4):290-306.

PMID:
11774232
44.

Multiple phosphorylation of alpha-synuclein by protein tyrosine kinase Syk prevents eosin-induced aggregation.

Negro A, Brunati AM, Donella-Deana A, Massimino ML, Pinna LA.

FASEB J. 2002 Feb;16(2):210-2. Epub 2001 Dec 14.

PMID:
11744621
45.

Autocatalytic tyrosine-phosphorylation of protein kinase CK2 alpha and alpha' subunits: implication of Tyr182.

Donella-Deana A, Cesaro L, Sarno S, Brunati AM, Ruzzene M, Pinna LA.

Biochem J. 2001 Jul 15;357(Pt 2):563-7.

46.

Distribution of protein disulphide isomerase in rat liver mitochondria.

Rigobello MP, Donella-Deana A, Cesaro L, Bindoli A.

Biochem J. 2001 Jun 1;356(Pt 2):567-70.

47.

Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').

Sarno S, Reddy H, Meggio F, Ruzzene M, Davies SP, Donella-Deana A, Shugar D, Pinna LA.

FEBS Lett. 2001 May 4;496(1):44-8.

48.

Isolation, purification, and characterization of a rat liver mitochondrial protein disulfide isomerase.

Rigobello MP, Donella-Deana A, Cesaro L, Bindoli A.

Free Radic Biol Med. 2000 Jan 15;28(2):266-72.

PMID:
11281294
50.

Sequential phosphorylation of protein band 3 by Syk and Lyn tyrosine kinases in intact human erythrocytes: identification of primary and secondary phosphorylation sites.

Brunati AM, Bordin L, Clari G, James P, Quadroni M, Baritono E, Pinna LA, Donella-Deana A.

Blood. 2000 Aug 15;96(4):1550-7.

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