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Items: 24


The Toxin-Antitoxin MazEF Drives Staphylococcus aureus Biofilm Formation, Antibiotic Tolerance, and Chronic Infection.

Ma D, Mandell JB, Donegan NP, Cheung AL, Ma W, Rothenberger S, Shanks RMQ, Richardson AR, Urish KL.

MBio. 2019 Nov 26;10(6). pii: e01658-19. doi: 10.1128/mBio.01658-19.


Interspecies interactions induce exploratory motility in Pseudomonas aeruginosa.

Limoli DH, Warren EA, Yarrington KD, Donegan NP, Cheung AL, O'Toole GA.

Elife. 2019 Nov 12;8. pii: e47365. doi: 10.7554/eLife.47365.


CspA regulation of Staphylococcus aureus carotenoid levels and σB activity is controlled by YjbH and Spx.

Donegan NP, Manna AC, Tseng CW, Liu GY, Cheung AL.

Mol Microbiol. 2019 Aug;112(2):532-551. doi: 10.1111/mmi.14273. Epub 2019 May 22.


Role of Purine Biosynthesis in Persistent Methicillin-Resistant Staphylococcus aureus Infection.

Li L, Abdelhady W, Donegan NP, Seidl K, Cheung A, Zhou YF, Yeaman MR, Bayer AS, Xiong YQ.

J Infect Dis. 2018 Sep 22;218(9):1367-1377. doi: 10.1093/infdis/jiy340.


Bypassing the Restriction System To Improve Transformation of Staphylococcus epidermidis.

Costa SK, Donegan NP, Corvaglia AR, François P, Cheung AL.

J Bacteriol. 2017 Jul 25;199(16). pii: e00271-17. doi: 10.1128/JB.00271-17. Print 2017 Aug 15.


Persister formation in Staphylococcus aureus is associated with ATP depletion.

Conlon BP, Rowe SE, Gandt AB, Nuxoll AS, Donegan NP, Zalis EA, Clair G, Adkins JN, Cheung AL, Lewis K.

Nat Microbiol. 2016 Apr 18;1:16051. doi: 10.1038/nmicrobiol.2016.51.


Persister formation in Staphylococcus aureus is associated with ATP depletion.

Conlon BP, Rowe SE, Gandt AB, Nuxoll AS, Donegan NP, Zalis EA, Clair G, Adkins JN, Cheung AL, Lewis K.

Nat Microbiol. 2016;1. pii: 16051. Epub 2016 Apr 18.


Effect of clpP and clpC deletion on persister cell number in Staphylococcus aureus.

Springer MT, Singh VK, Cheung AL, Donegan NP, Chamberlain NR.

J Med Microbiol. 2016 Aug;65(8):848-857. doi: 10.1099/jmm.0.000304. Epub 2016 Jul 1.


Improving transformation of Staphylococcus aureus belonging to the CC1, CC5 and CC8 clonal complexes.

Jones MJ, Donegan NP, Mikheyeva IV, Cheung AL.

PLoS One. 2015 Mar 25;10(3):e0119487. doi: 10.1371/journal.pone.0119487. eCollection 2015.


Role of adaptor TrfA and ClpPC in controlling levels of SsrA-tagged proteins and antitoxins in Staphylococcus aureus.

Donegan NP, Marvin JS, Cheung AL.

J Bacteriol. 2014 Dec;196(23):4140-51. doi: 10.1128/JB.02222-14. Epub 2014 Sep 15.


In vivo bioluminescence imaging to evaluate systemic and topical antibiotics against community-acquired methicillin-resistant Staphylococcus aureus-infected skin wounds in mice.

Guo Y, Ramos RI, Cho JS, Donegan NP, Cheung AL, Miller LS.

Antimicrob Agents Chemother. 2013 Feb;57(2):855-63. doi: 10.1128/AAC.01003-12. Epub 2012 Dec 3.


Crystallization of the Staphylococcus aureus MazF mRNA interferase.

Zorzini V, Haesaerts S, Donegan NP, Fu Z, Cheung AL, van Nuland NA, Loris R.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Mar 1;67(Pt 3):386-9. doi: 10.1107/S1744309111000571. Epub 2011 Feb 25.


Noninvasive in vivo imaging to evaluate immune responses and antimicrobial therapy against Staphylococcus aureus and USA300 MRSA skin infections.

Cho JS, Zussman J, Donegan NP, Ramos RI, Garcia NC, Uslan DZ, Iwakura Y, Simon SI, Cheung AL, Modlin RL, Kim J, Miller LS.

J Invest Dermatol. 2011 Apr;131(4):907-15. doi: 10.1038/jid.2010.417. Epub 2010 Dec 30.


The staphylococcus-specific gene rsr represses agr and virulence in Staphylococcus aureus.

Tamber S, Reyes D, Donegan NP, Schwartzman JD, Cheung AL, Memmi G.

Infect Immun. 2010 Oct;78(10):4384-91. doi: 10.1128/IAI.00401-10. Epub 2010 Aug 9.


Proteolytic regulation of toxin-antitoxin systems by ClpPC in Staphylococcus aureus.

Donegan NP, Thompson ET, Fu Z, Cheung AL.

J Bacteriol. 2010 Mar;192(5):1416-22. doi: 10.1128/JB.00233-09. Epub 2009 Dec 28.


Confinement-induced quorum sensing of individual Staphylococcus aureus bacteria.

Carnes EC, Lopez DM, Donegan NP, Cheung A, Gresham H, Timmins GS, Brinker CJ.

Nat Chem Biol. 2010 Jan;6(1):41-5. doi: 10.1038/nchembio.264. Epub 2009 Nov 22.


Regulation of the mazEF toxin-antitoxin module in Staphylococcus aureus and its impact on sigB expression.

Donegan NP, Cheung AL.

J Bacteriol. 2009 Apr;191(8):2795-805. doi: 10.1128/JB.01713-08. Epub 2009 Jan 30.


Overexpression of MazFsa in Staphylococcus aureus induces bacteriostasis by selectively targeting mRNAs for cleavage.

Fu Z, Tamber S, Memmi G, Donegan NP, Cheung AL.

J Bacteriol. 2009 Apr;191(7):2051-9. doi: 10.1128/JB.00907-08. Epub 2009 Jan 23.


Genetic evidence for an alternative citrate-dependent biofilm formation pathway in Staphylococcus aureus that is dependent on fibronectin binding proteins and the GraRS two-component regulatory system.

Shanks RM, Meehl MA, Brothers KM, Martinez RM, Donegan NP, Graber ML, Cheung AL, O'Toole GA.

Infect Immun. 2008 Jun;76(6):2469-77. doi: 10.1128/IAI.01370-07. Epub 2008 Mar 17.


Characterization of MazFSa, an endoribonuclease from Staphylococcus aureus.

Fu Z, Donegan NP, Memmi G, Cheung AL.

J Bacteriol. 2007 Dec;189(24):8871-9. Epub 2007 Oct 12.


Heparin stimulates Staphylococcus aureus biofilm formation.

Shanks RM, Donegan NP, Graber ML, Buckingham SE, Zegans ME, Cheung AL, O'Toole GA.

Infect Immun. 2005 Aug;73(8):4596-606.


Influences of sigmaB and agr on expression of staphylococcal enterotoxin B (seb) in Staphylococcus aureus.

Schmidt KA, Donegan NP, Kwan WA Jr, Cheung A.

Can J Microbiol. 2004 May;50(5):351-60.


Association of acyl-CoA synthetase-1 with GLUT4-containing vesicles.

Sleeman MW, Donegan NP, Heller-Harrison R, Lane WS, Czech MP.

J Biol Chem. 1998 Feb 6;273(6):3132-5.

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