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Items: 1 to 50 of 112

1.

Changes in cold-related mortalities between 1995 and 2016 in South East England.

Donaldson GC, Witt C, Näyhä S.

Public Health. 2019 Apr;169:36-40. doi: 10.1016/j.puhe.2019.01.008. Epub 2019 Feb 18.

PMID:
30782559
2.

Increased vulnerability of COPD patient groups to urban climate in view of global warming.

Hoffmann C, Hanisch M, Heinsohn JB, Dostal V, Jehn M, Liebers U, Pankow W, Donaldson GC, Witt C.

Int J Chron Obstruct Pulmon Dis. 2018 Oct 23;13:3493-3501. doi: 10.2147/COPD.S174148. eCollection 2018.

3.

Increased Chronic Obstructive Pulmonary Disease Exacerbations of Likely Viral Etiology Follow Elevated Ambient Nitrogen Oxides.

Pfeffer PE, Donaldson GC, Mackay AJ, Wedzicha JA.

Am J Respir Crit Care Med. 2019 Mar 1;199(5):581-591. doi: 10.1164/rccm.201712-2506OC.

4.

Childhood Exposures, Asthma, Smoking, Interactions, and the Catch-Up Hypothesis.

Allinson JP, Hardy R, Donaldson GC, Wedzicha JA.

Ann Am Thorac Soc. 2018 Oct;15(10):1241-1242. doi: 10.1513/AnnalsATS.201807-444LE. No abstract available.

5.

An Alternative Approach for the Analysis of Time-to-Event and Survival Outcomes in Pulmonary Medicine.

Harhay MO, Porcher R, Cantu E, Crowther MJ, Christie JD, Thabut G, Donaldson GC.

Am J Respir Crit Care Med. 2018 Sep 1;198(5):684-687. doi: 10.1164/rccm.201801-0189LE. No abstract available.

6.

Is Peer Review Still Anonymous?

Ritchie AI, Polkey MI, Donaldson GC, Wedzicha JA.

Am J Respir Crit Care Med. 2018 Jul 15;198(2):278-280. doi: 10.1164/rccm.201711-2257LE. No abstract available.

7.

Sputum microbiome temporal variability and dysbiosis in chronic obstructive pulmonary disease exacerbations: an analysis of the COPDMAP study.

Wang Z, Singh R, Miller BE, Tal-Singer R, Van Horn S, Tomsho L, Mackay A, Allinson JP, Webb AJ, Brookes AJ, George LM, Barker B, Kolsum U, Donnelly LE, Belchamber K, Barnes PJ, Singh D, Brightling CE, Donaldson GC, Wedzicha JA, Brown JR; COPDMAP.

Thorax. 2018 Apr;73(4):331-338. doi: 10.1136/thoraxjnl-2017-210741. Epub 2017 Dec 21.

8.

Combined Impact of Smoking and Early-Life Exposures on Adult Lung Function Trajectories.

Allinson JP, Hardy R, Donaldson GC, Shaheen SO, Kuh D, Wedzicha JA.

Am J Respir Crit Care Med. 2017 Oct 15;196(8):1021-1030. doi: 10.1164/rccm.201703-0506OC.

9.

Blood and sputum eosinophils in COPD; relationship with bacterial load.

Kolsum U, Donaldson GC, Singh R, Barker BL, Gupta V, George L, Webb AJ, Thurston S, Brookes AJ, McHugh TD, Wedzicha JA, Brightling CE, Singh D.

Respir Res. 2017 May 8;18(1):88. doi: 10.1186/s12931-017-0570-5.

10.

Prediction of Chronic Obstructive Pulmonary Disease Exacerbation Frequency. Clinical Parameters Are Still Better Than Biomarkers.

Donaldson GC, Wedzicha JA.

Am J Respir Crit Care Med. 2017 Feb 15;195(4):415-416. doi: 10.1164/rccm.201610-2037ED. No abstract available.

11.

Randomized Double-Blind Controlled Trial of Roflumilast at Acute Exacerbations of Chronic Obstructive Pulmonary Disease.

Mackay AJ, Patel ARC, Singh R, Sapsford RJ, Donaldson GC, Prasad N, Goehring UM, Nip TK, Wedzicha JA.

Am J Respir Crit Care Med. 2017 Sep 1;196(5):656-659. doi: 10.1164/rccm.201612-2518LE. No abstract available.

12.

Misspecification of at-risk periods and distributional assumptions in estimating COPD exacerbation rates: The resultant bias in treatment effect estimation.

Law M, Sweeting MJ, Donaldson GC, Wedzicha JA.

Pharm Stat. 2017 May;16(3):201-209. doi: 10.1002/pst.1798. Epub 2016 Dec 14.

13.

Physical activity and exercise capacity in patients with moderate COPD exacerbations.

Alahmari AD, Kowlessar BS, Patel AR, Mackay AJ, Allinson JP, Wedzicha JA, Donaldson GC.

Eur Respir J. 2016 Aug;48(2):340-9. doi: 10.1183/13993003.01105-2015. Epub 2016 Apr 28.

14.

The Presence of Chronic Mucus Hypersecretion across Adult Life in Relation to Chronic Obstructive Pulmonary Disease Development.

Allinson JP, Hardy R, Donaldson GC, Shaheen SO, Kuh D, Wedzicha JA.

Am J Respir Crit Care Med. 2016 Mar 15;193(6):662-72. doi: 10.1164/rccm.201511-2210OC.

15.

Effects of different antibiotic classes on airway bacteria in stable COPD using culture and molecular techniques: a randomised controlled trial.

Brill SE, Law M, El-Emir E, Allinson JP, James P, Maddox V, Donaldson GC, McHugh TD, Cookson WO, Moffatt MF, Nazareth I, Hurst JR, Calverley PM, Sweeting MJ, Wedzicha JA.

Thorax. 2015 Oct;70(10):930-8. doi: 10.1136/thoraxjnl-2015-207194. Epub 2015 Jul 15.

16.

Impact of Prolonged Exacerbation Recovery in Chronic Obstructive Pulmonary Disease.

Donaldson GC, Law M, Kowlessar B, Singh R, Brill SE, Allinson JP, Wedzicha JA.

Am J Respir Crit Care Med. 2015 Oct 15;192(8):943-50. doi: 10.1164/rccm.201412-2269OC.

17.

Influence of weather and atmospheric pollution on physical activity in patients with COPD.

Alahmari AD, Mackay AJ, Patel AR, Kowlessar BS, Singh R, Brill SE, Allinson JP, Wedzicha JA, Donaldson GC.

Respir Res. 2015 Jun 13;16:71. doi: 10.1186/s12931-015-0229-z.

18.

Upper respiratory symptoms worsen over time and relate to clinical phenotype in chronic obstructive pulmonary disease.

Huerta A, Donaldson GC, Singh R, Mackay AJ, Allinson JP, Brill SE, Kowlessar B, Torres A, Wedzicha JA.

Ann Am Thorac Soc. 2015 Jul;12(7):997-1004. doi: 10.1513/AnnalsATS.201408-359OC.

19.

The causes and consequences of seasonal variation in COPD exacerbations.

Donaldson GC, Wedzicha JA.

Int J Chron Obstruct Pulmon Dis. 2014 Oct 6;9:1101-10. doi: 10.2147/COPD.S54475. eCollection 2014. Review.

20.

Inflammatory thresholds and the species-specific effects of colonising bacteria in stable chronic obstructive pulmonary disease.

Singh R, Mackay AJ, Patel AR, Garcha DS, Kowlessar BS, Brill SE, Donnelly LE, Barnes PJ, Donaldson GC, Wedzicha JA.

Respir Res. 2014 Sep 14;15:114. doi: 10.1186/s12931-014-0114-1.

21.

Trends in management and outcomes of COPD patients in primary care, 2000-2009: a retrospective cohort study.

James GD, Donaldson GC, Wedzicha JA, Nazareth I.

NPJ Prim Care Respir Med. 2014 Jul 3;24:14015. doi: 10.1038/npjpcrm.2014.15.

22.

Daily activity during stability and exacerbation of chronic obstructive pulmonary disease.

Alahmari AD, Patel AR, Kowlessar BS, Mackay AJ, Singh R, Wedzicha JA, Donaldson GC.

BMC Pulm Med. 2014 Jun 2;14:98. doi: 10.1186/1471-2466-14-98.

23.

The CODEX index: a collection or digest of laws: a code.

Donaldson GC, Wedzicha JA.

Chest. 2014 May;145(5):934-935. doi: 10.1378/chest.13-2678. No abstract available.

PMID:
24798828
24.

Exacerbations in non-COPD patients: recognition?

Donaldson GC.

Thorax. 2014 Aug;69(8):689-90. doi: 10.1136/thoraxjnl-2014-205355. Epub 2014 May 1. No abstract available.

PMID:
24794419
25.

Rapid FEV1 decline, early COPD, and angiotensin-converting enzymes?

Wedzicha JA, Donaldson GC.

Chest. 2014 Apr;145(4):671-672. doi: 10.1378/chest.13-2696. No abstract available.

PMID:
24687700
26.

Human rhinovirus infection during naturally occurring COPD exacerbations.

George SN, Garcha DS, Mackay AJ, Patel AR, Singh R, Sapsford RJ, Donaldson GC, Wedzicha JA.

Eur Respir J. 2014 Jul;44(1):87-96. doi: 10.1183/09031936.00223113. Epub 2014 Mar 13.

27.

Community-based recruitment of patients with COPD into clinical research.

Brill SE, El-Emir E, Allinson JP, Donaldson GC, Nazareth I, Wedzicha JA.

Thorax. 2014 Oct;69(10):951-2. doi: 10.1136/thoraxjnl-2014-205253. Epub 2014 Mar 4.

28.

Long-term antibiotic therapy reduces exacerbation frequency in patients with COPD but it remains unclear which patients to target.

Allinson JP, Donaldson GC.

Evid Based Med. 2014 Jun;19(3):99. doi: 10.1136/eb-2013-101711. Epub 2014 Feb 7. No abstract available.

PMID:
24510481
29.

Cardiovascular risk, myocardial injury, and exacerbations of chronic obstructive pulmonary disease.

Patel AR, Kowlessar BS, Donaldson GC, Mackay AJ, Singh R, George SN, Garcha DS, Wedzicha JA, Hurst JR.

Am J Respir Crit Care Med. 2013 Nov 1;188(9):1091-9. doi: 10.1164/rccm.201306-1170OC.

30.

Detection and severity grading of COPD exacerbations using the exacerbations of chronic pulmonary disease tool (EXACT).

Mackay AJ, Donaldson GC, Patel AR, Singh R, Kowlessar B, Wedzicha JA.

Eur Respir J. 2014 Mar;43(3):735-44. doi: 10.1183/09031936.00110913. Epub 2013 Aug 29.

31.

Deprivation, winter season, and COPD exacerbations.

Donaldson GC, Wedzicha JA.

Prim Care Respir J. 2013 Sep;22(3):264-5. doi: 10.4104/pcrj.2013.00078. No abstract available.

32.

Mechanisms and impact of the frequent exacerbator phenotype in chronic obstructive pulmonary disease.

Wedzicha JA, Brill SE, Allinson JP, Donaldson GC.

BMC Med. 2013 Aug 14;11:181. doi: 10.1186/1741-7015-11-181. Review.

33.

Factors associated with change in exacerbation frequency in COPD.

Donaldson GC, Müllerova H, Locantore N, Hurst JR, Calverley PM, Vestbo J, Anzueto A, Wedzicha JA.

Respir Res. 2013 Jul 30;14:79. doi: 10.1186/1465-9921-14-79.

34.

Use of long-term antibiotic treatment in COPD patients in the UK: a retrospective cohort study.

James GD, Petersen I, Nazareth I, Wedzicha JA, Donaldson GC.

Prim Care Respir J. 2013 Sep;22(3):271-7. doi: 10.4104/pcrj.2013.00061.

35.

Changes in prevalence and load of airway bacteria using quantitative PCR in stable and exacerbated COPD.

Garcha DS, Thurston SJ, Patel AR, Mackay AJ, Goldring JJ, Donaldson GC, McHugh TD, Wedzicha JA.

Thorax. 2012 Dec;67(12):1075-80. doi: 10.1136/thoraxjnl-2012-201924. Epub 2012 Aug 3.

PMID:
22863758
36.

Natural history of successive COPD exacerbations.

Wedzicha JA, Donaldson GC.

Thorax. 2012 Nov;67(11):935-6. doi: 10.1136/thoraxjnl-2012-202087. Epub 2012 Aug 2. No abstract available.

PMID:
22858927
37.

25-hydroxyvitamin D deficiency, exacerbation frequency and human rhinovirus exacerbations in chronic obstructive pulmonary disease.

Quint JK, Donaldson GC, Wassef N, Hurst JR, Thomas M, Wedzicha JA.

BMC Pulm Med. 2012 Jun 22;12:28. doi: 10.1186/1471-2466-12-28.

38.

Detrended fluctuation analysis of peak expiratory flow and exacerbation frequency in COPD.

Donaldson GC, Seemungal TA, Hurst JR, Wedzicha JA.

Eur Respir J. 2012 Nov;40(5):1123-9. doi: 10.1183/09031936.00180811. Epub 2012 Feb 9.

39.

Usefulness of the Chronic Obstructive Pulmonary Disease Assessment Test to evaluate severity of COPD exacerbations.

Mackay AJ, Donaldson GC, Patel AR, Jones PW, Hurst JR, Wedzicha JA.

Am J Respir Crit Care Med. 2012 Jun 1;185(11):1218-24. doi: 10.1164/rccm.201110-1843OC. Epub 2012 Jan 26.

PMID:
22281834
40.

Time course and pattern of COPD exacerbation onset.

Aaron SD, Donaldson GC, Whitmore GA, Hurst JR, Ramsay T, Wedzicha JA.

Thorax. 2012 Mar;67(3):238-43. doi: 10.1136/thoraxjnl-2011-200768. Epub 2011 Oct 18.

PMID:
22008189
41.

The impact of ischemic heart disease on symptoms, health status, and exacerbations in patients with COPD.

Patel ARC, Donaldson GC, Mackay AJ, Wedzicha JA, Hurst JR.

Chest. 2012 Apr;141(4):851-857. doi: 10.1378/chest.11-0853. Epub 2011 Sep 22.

PMID:
21940771
42.

Influence of season on exacerbation characteristics in patients with COPD.

Donaldson GC, Goldring JJ, Wedzicha JA.

Chest. 2012 Jan;141(1):94-100. doi: 10.1378/chest.11-0281. Epub 2011 Jul 28.

PMID:
21799024
43.

SERPINA1 11478G→A variant, serum α1-antitrypsin, exacerbation frequency and FEV1 decline in COPD.

Quint JK, Donaldson GC, Kumari M, Talmud PJ, Hurst JR.

Thorax. 2011 May;66(5):418-24. doi: 10.1136/thx.2010.152975. Epub 2011 Feb 18.

PMID:
21335450
44.

Domiciliary pulse-oximetry at exacerbation of chronic obstructive pulmonary disease: prospective pilot study.

Hurst JR, Donaldson GC, Quint JK, Goldring JJ, Patel AR, Wedzicha JA.

BMC Pulm Med. 2010 Oct 20;10:52. doi: 10.1186/1471-2466-10-52.

45.

Predictive accuracy of patient-reported exacerbation frequency in COPD.

Quint JK, Donaldson GC, Hurst JR, Goldring JJ, Seemungal TR, Wedzicha JA.

Eur Respir J. 2011 Mar;37(3):501-7. doi: 10.1183/09031936.00035909. Epub 2010 Jul 22.

46.

Use of home oxygen for children in England and Wales.

Primhak RA, Hicks B, Shaw NJ, Donaldson GC, Balfour-Lynn IM.

Arch Dis Child. 2011 Apr;96(4):389-92. doi: 10.1136/adc.2009.180653. Epub 2010 Jun 3.

PMID:
20522469
47.

Increased risk of myocardial infarction and stroke following exacerbation of COPD.

Donaldson GC, Hurst JR, Smith CJ, Hubbard RB, Wedzicha JA.

Chest. 2010 May;137(5):1091-7. doi: 10.1378/chest.09-2029. Epub 2009 Dec 18.

PMID:
20022970
48.

Serum IP-10 as a biomarker of human rhinovirus infection at exacerbation of COPD.

Quint JK, Donaldson GC, Goldring JJ, Baghai-Ravary R, Hurst JR, Wedzicha JA.

Chest. 2010 Apr;137(4):812-22. doi: 10.1378/chest.09-1541. Epub 2009 Oct 16.

49.

Derivation and validation of a composite index of severity in chronic obstructive pulmonary disease: the DOSE Index.

Jones RC, Donaldson GC, Chavannes NH, Kida K, Dickson-Spillmann M, Harding S, Wedzicha JA, Price D, Hyland ME.

Am J Respir Crit Care Med. 2009 Dec 15;180(12):1189-95. doi: 10.1164/rccm.200902-0271OC. Epub 2009 Sep 24.

PMID:
19797160
50.

Temporal clustering of exacerbations in chronic obstructive pulmonary disease.

Hurst JR, Donaldson GC, Quint JK, Goldring JJ, Baghai-Ravary R, Wedzicha JA.

Am J Respir Crit Care Med. 2009 Mar 1;179(5):369-74. doi: 10.1164/rccm.200807-1067OC. Epub 2008 Dec 12.

PMID:
19074596

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