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LRP receptors in chondrocytes are modulated by simulated microgravity and cyclic hydrostatic pressure.

Nordberg RC, Mellor LF, Krause AR, Donahue HJ, Loboa EG.

PLoS One. 2019 Oct 4;14(10):e0223245. doi: 10.1371/journal.pone.0223245. eCollection 2019.


Single limb immobilization model for bone loss from unloading.

Friedman MA, Zhang Y, Wayne JS, Farber CR, Donahue HJ.

J Biomech. 2019 Jan 23;83:181-189. doi: 10.1016/j.jbiomech.2018.11.049. Epub 2018 Dec 5.


The Effects of Hind Limb Suspension and Cast Mediated Immobilization on Bone Strength Properties.

Sanseverino MJ, Speacht TL, Donahue HJ, Lau AG.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:1747-1750. doi: 10.1109/EMBC.2018.8512691.


Combination of hindlimb suspension and immobilization by casting exaggerates sarcopenia by stimulating autophagy but does not worsen osteopenia.

Speacht TL, Krause AR, Steiner JL, Lang CH, Donahue HJ.

Bone. 2018 May;110:29-37. doi: 10.1016/j.bone.2018.01.026. Epub 2018 Feb 3.


Joint diseases: from connexins to gap junctions.

Donahue HJ, Qu RW, Genetos DC.

Nat Rev Rheumatol. 2017 Dec 19;14(1):42-51. doi: 10.1038/nrrheum.2017.204. Review.


Characterization of Thyroid Disorders in Patients Receiving Immune Checkpoint Inhibition Therapy.

Lee H, Hodi FS, Giobbie-Hurder A, Ott PA, Buchbinder EI, Haq R, Tolaney S, Barroso-Sousa R, Zhang K, Donahue H, Davis M, Gargano ME, Kelley KM, Carroll RS, Kaiser UB, Min L.

Cancer Immunol Res. 2017 Dec;5(12):1133-1140. doi: 10.1158/2326-6066.CIR-17-0208. Epub 2017 Oct 27.


Simulated space radiation sensitizes bone but not muscle to the catabolic effects of mechanical unloading.

Krause AR, Speacht TL, Zhang Y, Lang CH, Donahue HJ.

PLoS One. 2017 Aug 2;12(8):e0182403. doi: 10.1371/journal.pone.0182403. eCollection 2017.


Diagnostic Comparison of CT Scans and Colonoscopy for Immune-Related Colitis in Ipilimumab-Treated Advanced Melanoma Patients.

Garcia-Neuer M, Marmarelis ME, Jangi SR, Luke JJ, Ibrahim N, Davis M, Weinberg J, Donahue H, Bailey N, Hodi FS, Buchbinder EL, Ott PA.

Cancer Immunol Res. 2017 Apr;5(4):286-291. doi: 10.1158/2326-6066.CIR-16-0302.


Mechanical Loading Attenuates Radiation-Induced Bone Loss in Bone Marrow Transplanted Mice.

Govey PM, Zhang Y, Donahue HJ.

PLoS One. 2016 Dec 9;11(12):e0167673. doi: 10.1371/journal.pone.0167673. eCollection 2016.


Time course of peri-implant bone regeneration around loaded and unloaded implants in a rat model.

Jariwala SH, Wee H, Roush EP, Whitcomb TL, Murter C, Kozlansky G, Lakhtakia A, Kunselman AR, Donahue HJ, Armstrong AD, Lewis GS.

J Orthop Res. 2017 May;35(5):997-1006. doi: 10.1002/jor.23360. Epub 2016 Jul 20.


Biomimetic substrate control of cellular mechanotransduction.

Andalib MN, Dzenis Y, Donahue HJ, Lim JY.

Biomater Res. 2016 Apr 29;20:11. doi: 10.1186/s40824-016-0059-1. eCollection 2016. Review.


Mapping the osteocytic cell response to fluid flow using RNA-Seq.

Govey PM, Kawasawa YI, Donahue HJ.

J Biomech. 2015 Dec 16;48(16):4327-32. doi: 10.1016/j.jbiomech.2015.10.045. Epub 2015 Nov 5.


3D Printing of Personalized Artificial Bone Scaffolds.

Jariwala SH, Lewis GS, Bushman ZJ, Adair JH, Donahue HJ.

3D Print Addit Manuf. 2015 Jun 1;2(2):56-64. doi: 10.1089/3dp.2015.0001.


Single Institution Experience of Ipilimumab 3 mg/kg with Sargramostim (GM-CSF) in Metastatic Melanoma.

Luke JJ, Donahue H, Nishino M, Giobbie-Hurder A, Davis M, Bailey N, Ott PA, Hodi FS.

Cancer Immunol Res. 2015 Sep;3(9):986-91. doi: 10.1158/2326-6066.CIR-15-0066. Epub 2015 May 5.


Cx43 and mechanotransduction in bone.

Plotkin LI, Speacht TL, Donahue HJ.

Curr Osteoporos Rep. 2015 Apr;13(2):67-72. doi: 10.1007/s11914-015-0255-2. Review.


Systemic high-dose corticosteroid treatment does not improve the outcome of ipilimumab-related hypophysitis: a retrospective cohort study.

Min L, Hodi FS, Giobbie-Hurder A, Ott PA, Luke JJ, Donahue H, Davis M, Carroll RS, Kaiser UB.

Clin Cancer Res. 2015 Feb 15;21(4):749-55. doi: 10.1158/1078-0432.CCR-14-2353. Epub 2014 Dec 23.


Drug-associated dermatomyositis following ipilimumab therapy: a novel immune-mediated adverse event associated with cytotoxic T-lymphocyte antigen 4 blockade.

Sheik Ali S, Goddard AL, Luke JJ, Donahue H, Todd DJ, Werchniak A, Vleugels RA.

JAMA Dermatol. 2015 Feb;151(2):195-9. doi: 10.1001/jamadermatol.2014.2233.


The roles of P2Y2 purinergic receptors in osteoblasts and mechanotransduction.

Xing Y, Gu Y, Bresnahan JJ, Paul EM, Donahue HJ, You J.

PLoS One. 2014 Sep 30;9(9):e108417. doi: 10.1371/journal.pone.0108417. eCollection 2014.


Single Nucleotide Polymorphisms in Osteogenic Genes in Atrophic Delayed Fracture-Healing: A Preliminary Investigation.

Sathyendra V, Donahue HJ, Vrana KE, Berg A, Fryzel D, Gandhi J, Reid JS.

J Bone Joint Surg Am. 2014 Aug 6;96(15):1242-1248. Epub 2014 Aug 6.


Integrative transcriptomic and proteomic analysis of osteocytic cells exposed to fluid flow reveals novel mechano-sensitive signaling pathways.

Govey PM, Jacobs JM, Tilton SC, Loiselle AE, Zhang Y, Freeman WM, Waters KM, Karin NJ, Donahue HJ.

J Biomech. 2014 Jun 3;47(8):1838-45. doi: 10.1016/j.jbiomech.2014.03.022. Epub 2014 Mar 25.


Evidence for the role of connexin 43-mediated intercellular communication in the process of intracortical bone resorption via osteocytic osteolysis.

Lloyd SA, Loiselle AE, Zhang Y, Donahue HJ.

BMC Musculoskelet Disord. 2014 Apr 9;15:122. doi: 10.1186/1471-2474-15-122.


Shifting paradigms on the role of connexin43 in the skeletal response to mechanical load.

Lloyd SA, Loiselle AE, Zhang Y, Donahue HJ.

J Bone Miner Res. 2014 Feb;29(2):275-86. Review.


Inhibition of GSK-3β rescues the impairments in bone formation and mechanical properties associated with fracture healing in osteoblast selective connexin 43 deficient mice.

Loiselle AE, Lloyd SA, Paul EM, Lewis GS, Donahue HJ.

PLoS One. 2013 Nov 8;8(11):e81399. doi: 10.1371/journal.pone.0081399. eCollection 2013.


Interdependence of muscle atrophy and bone loss induced by mechanical unloading.

Lloyd SA, Lang CH, Zhang Y, Paul EM, Laufenberg LJ, Lewis GS, Donahue HJ.

J Bone Miner Res. 2014;29(5):1118-30. doi: 10.1002/jbmr.2113.


Connexin 43 deficiency desensitizes bone to the effects of mechanical unloading through modulation of both arms of bone remodeling.

Lloyd SA, Loiselle AE, Zhang Y, Donahue HJ.

Bone. 2013 Nov;57(1):76-83. doi: 10.1016/j.bone.2013.07.022. Epub 2013 Jul 24.


Genomic approaches in breast cancer research.

Donahue HJ, Genetos DC.

Brief Funct Genomics. 2013 Sep;12(5):391-6. doi: 10.1093/bfgp/elt019. Epub 2013 Jun 20. Review.


BRMS1 Sensitizes Breast Cancer Cells to ATP-Induced Growth Suppression.

Zhang Y, Chin-Quee K, Riddle RC, Li Z, Zhou Z, Donahue HJ.

Biores Open Access. 2013 Apr;2(2):77-83. doi: 10.1089/biores.2012.0260.


Biophysical regulation of stem cell differentiation.

Govey PM, Loiselle AE, Donahue HJ.

Curr Osteoporos Rep. 2013 Jun;11(2):83-91. doi: 10.1007/s11914-013-0138-3. Review.


Nanotopographic cell culture substrate: polymer-demixed nanotextured films under cell culture conditions.

Lim JY, Siedlecki CA, Donahue HJ.

Biores Open Access. 2012 Oct;1(5):252-5. doi: 10.1089/biores.2012.0255.


Specific biomimetic hydroxyapatite nanotopographies enhance osteoblastic differentiation and bone graft osteointegration.

Loiselle AE, Wei L, Faryad M, Paul EM, Lewis GS, Gao J, Lakhtakia A, Donahue HJ.

Tissue Eng Part A. 2013 Aug;19(15-16):1704-12. doi: 10.1089/ten.TEA.2012.0560. Epub 2013 Apr 25.


Identification of novel CDK9 and Cyclin T1-associated protein complexes (CCAPs) whose siRNA depletion enhances HIV-1 Tat function.

Ramakrishnan R, Liu H, Donahue H, Malovannaya A, Qin J, Rice AP.

Retrovirology. 2012 Oct 30;9:90. doi: 10.1186/1742-4690-9-90.


Gap junction and hemichannel functions in osteocytes.

Loiselle AE, Jiang JX, Donahue HJ.

Bone. 2013 Jun;54(2):205-12. doi: 10.1016/j.bone.2012.08.132. Epub 2012 Oct 13. Review.


Osteoblast and osteocyte-specific loss of Connexin43 results in delayed bone formation and healing during murine fracture healing.

Loiselle AE, Paul EM, Lewis GS, Donahue HJ.

J Orthop Res. 2013 Jan;31(1):147-54. doi: 10.1002/jor.22178. Epub 2012 Jun 20.


Connexin 43 deficiency attenuates loss of trabecular bone and prevents suppression of cortical bone formation during unloading.

Lloyd SA, Lewis GS, Zhang Y, Paul EM, Donahue HJ.

J Bone Miner Res. 2012 Nov;27(11):2359-72. doi: 10.1002/jbmr.1687.


Age-related changes in gap junctional intercellular communication in osteoblastic cells.

Genetos DC, Zhou Z, Li Z, Donahue HJ.

J Orthop Res. 2012 Dec;30(12):1979-84. doi: 10.1002/jor.22172. Epub 2012 Jun 13.


Making a Short Story Long: Regulation of P-TEFb and HIV-1 Transcriptional Elongation in CD4+ T Lymphocytes and Macrophages.

Ramakrishnan R, Chiang K, Liu H, Budhiraja S, Donahue H, Rice AP.

Biology (Basel). 2012 Jun 15;1(1):94-115. doi: 10.3390/biology1010094.


Epstein-Barr virus BART9 miRNA modulates LMP1 levels and affects growth rate of nasal NK T cell lymphomas.

Ramakrishnan R, Donahue H, Garcia D, Tan J, Shimizu N, Rice AP, Ling PD.

PLoS One. 2011;6(11):e27271. doi: 10.1371/journal.pone.0027271. Epub 2011 Nov 10.


Enhanced osteoclastic resorption and responsiveness to mechanical load in gap junction deficient bone.

Zhang Y, Paul EM, Sathyendra V, Davison A, Sharkey N, Bronson S, Srinivasan S, Gross TS, Donahue HJ.

PLoS One. 2011;6(8):e23516. doi: 10.1371/journal.pone.0023516. Epub 2011 Aug 29.


Effects of membrane cholesterol depletion and GPI-anchored protein reduction on osteoblastic mechanotransduction.

Xing Y, Gu Y, Xu LC, Siedlecki CA, Donahue HJ, You J.

J Cell Physiol. 2011 Sep;226(9):2350-9. doi: 10.1002/jcp.22579.


A new feature of the journal of orthopaedic research: research perspectives.

Buckwalter JA, Wright TM, Donahue HJ.

J Orthop Res. 2011 Jun;29(6):801. doi: 10.1002/jor.21391. Epub 2011 Feb 24. No abstract available.


Optimizing the osteogenic potential of adult stem cells for skeletal regeneration.

Lim JY, Loiselle AE, Lee JS, Zhang Y, Salvi JD, Donahue HJ.

J Orthop Res. 2011 Nov;29(11):1627-33. doi: 10.1002/jor.21441. Epub 2011 Apr 20.


Purinergic signaling is required for fluid shear stress-induced NF-κB translocation in osteoblasts.

Genetos DC, Karin NJ, Geist DJ, Donahue HJ, Duncan RL.

Exp Cell Res. 2011 Apr 1;317(6):737-44. doi: 10.1016/j.yexcr.2011.01.007. Epub 2011 Jan 13.


Estrogen receptor expression in posterior tibial tendon dysfunction: a pilot study.

Bridgeman JT, Zhang Y, Donahue H, Wade AM, Juliano PJ.

Foot Ankle Int. 2010 Dec;31(12):1081-4. doi: 10.3113/FAI.2010.1081.


Gap Junctions and Biophysical Regulation of Bone Cells.

Lloyd SA, Donahue HJ.

Clin Rev Bone Miner Metab. 2010 Dec 1;8(4):189-200.


Attenuation of arthritis in rodents by a novel orally-available inhibitor of sphingosine kinase.

Fitzpatrick LR, Green C, Frauenhoffer EE, French KJ, Zhuang Y, Maines LW, Upson JJ, Paul E, Donahue H, Mosher TJ, Smith CD.

Inflammopharmacology. 2011 Apr;19(2):75-87. doi: 10.1007/s10787-010-0060-6. Epub 2010 Oct 11.


Increased mechanosensitivity of cells cultured on nanotopographies.

Salvi JD, Lim JY, Donahue HJ.

J Biomech. 2010 Nov 16;43(15):3058-62. doi: 10.1016/j.jbiomech.2010.07.015. Epub 2010 Sep 20.


Finite element analyses of fluid flow conditions in cell culture.

Salvi JD, Lim JY, Donahue HJ.

Tissue Eng Part C Methods. 2010 Aug;16(4):661-70. doi: 10.1089/ten.TEC.2009.0159.


Gap junctions and osteoblast-like cell gene expression in response to fluid flow.

Jekir MG, Donahue HJ.

J Biomech Eng. 2009 Jan;131(1):011005. doi: 10.1115/1.3005201.


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