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Items: 1 to 50 of 321

1.

Anti-Mullerian Hormone and Impending Menopause in Late Reproductive Age: The Study of Women's Health Across the Nation.

Finkelstein JS, Lee H, Karlamangla A, Neer RM, Sluss PM, Burnett-Bowie SM, Darakananda K, Donahoe PK, Harlow SD, Prizand SH, Joffe H, Kumar A, Martin DE, McConnell D, Merrilat S, Morrison A, Pastore LM, Randolph JF, Greendale GA, Santoro N.

J Clin Endocrinol Metab. 2020 Jan 22. pii: dgz283. doi: 10.1210/clinem/dgz283. [Epub ahead of print]

PMID:
31965189
2.

Neoadjuvant Treatment With Müllerian-Inhibiting Substance Synchronizes Follicles and Enhances Superovulation Yield.

Kano M, Hsu JY, Saatcioglu HD, Nagykery N, Zhang L, Morris Sabatini ME, Donahoe PK, Pépin D.

J Endocr Soc. 2019 Jul 22;3(11):2123-2134. doi: 10.1210/js.2019-00190. eCollection 2019 Nov 1.

3.

Single-cell sequencing of neonatal uterus reveals an Misr2+ endometrial progenitor indispensable for fertility.

Saatcioglu HD, Kano M, Horn H, Zhang L, Samore W, Nagykery N, Meinsohn MC, Hyun M, Suliman R, Poulo J, Hsu J, Sacha C, Wang D, Gao G, Lage K, Oliva E, Morris Sabatini ME, Donahoe PK, Pépin D.

Elife. 2019 Jun 24;8. pii: e46349. doi: 10.7554/eLife.46349.

4.

De novo variants in congenital diaphragmatic hernia identify MYRF as a new syndrome and reveal genetic overlaps with other developmental disorders.

Qi H, Yu L, Zhou X, Wynn J, Zhao H, Guo Y, Zhu N, Kitaygorodsky A, Hernan R, Aspelund G, Lim FY, Crombleholme T, Cusick R, Azarow K, Danko ME, Chung D, Warner BW, Mychaliska GB, Potoka D, Wagner AJ, ElFiky M, Wilson JM, Nickerson D, Bamshad M, High FA, Longoni M, Donahoe PK, Chung WK, Shen Y.

PLoS Genet. 2018 Dec 10;14(12):e1007822. doi: 10.1371/journal.pgen.1007822. eCollection 2018 Dec.

5.

Müllerian inhibiting substance/anti-Müllerian hormone as a fertility preservation agent.

Pépin D, Sabatini ME, Donahoe PK.

Curr Opin Endocrinol Diabetes Obes. 2018 Dec;25(6):399-405. doi: 10.1097/MED.0000000000000442. Review.

PMID:
30320617
6.

Towards international standardization of immunoassays for Müllerian inhibiting substance/anti-Müllerian hormone.

Ferguson JM, Pépin D, Duru C, Matejtschuk P, Donahoe PK, Burns CJ.

Reprod Biomed Online. 2018 Nov;37(5):631-640. doi: 10.1016/j.rbmo.2018.08.012. Epub 2018 Sep 5.

7.

Müllerian-Inhibiting Substance/Anti-Müllerian Hormone as a Predictor of Preterm Birth in Polycystic Ovary Syndrome.

Hsu JY, James KE, Bormann CL, Donahoe PK, Pépin D, Sabatini ME.

J Clin Endocrinol Metab. 2018 Nov 1;103(11):4187-4196. doi: 10.1210/jc.2018-01320.

PMID:
30239805
8.

Systematic analysis of copy number variation associated with congenital diaphragmatic hernia.

Zhu Q, High FA, Zhang C, Cerveira E, Russell MK, Longoni M, Joy MP, Ryan M, Mil-Homens A, Bellfy L, Coletti CM, Bhayani P, Hila R, Wilson JM, Donahoe PK, Lee C.

Proc Natl Acad Sci U S A. 2018 May 15;115(20):5247-5252. doi: 10.1073/pnas.1714885115. Epub 2018 Apr 30.

9.

Genome-wide enrichment of damaging de novo variants in patients with isolated and complex congenital diaphragmatic hernia.

Longoni M, High FA, Qi H, Joy MP, Hila R, Coletti CM, Wynn J, Loscertales M, Shan L, Bult CJ, Wilson JM, Shen Y, Chung WK, Donahoe PK.

Hum Genet. 2017 Jun;136(6):679-691. doi: 10.1007/s00439-017-1774-y. Epub 2017 Mar 16.

10.

Müllerian inhibiting substance inhibits an ovarian cancer cell line via β-catenin interacting protein deregulation of the Wnt signal pathway.

Park SH, Chung YJ, Song JY, Kim SI, Pépin D, MacLaughlin DT, Donahoe PK, Kim JH.

Int J Oncol. 2017 Mar;50(3):1022-1028. doi: 10.3892/ijo.2017.3874. Epub 2017 Feb 13.

PMID:
28197641
11.

AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy.

Kano M, Sosulski AE, Zhang L, Saatcioglu HD, Wang D, Nagykery N, Sabatini ME, Gao G, Donahoe PK, Pépin D.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):E1688-E1697. doi: 10.1073/pnas.1620729114. Epub 2017 Jan 30.

12.

Erratum to: Type IV collagen drives alveolar epithelial-endothelial association and the morphogenetic movements of septation.

Loscertales M, Nicolaou F, Jeanne M, Longoni M, Gould DB, Sun Y, Maalouf FI, Nagy N, Donahoe PK.

BMC Biol. 2016 Sep 1;14(1):73. No abstract available.

13.

Polygenic Causes of Congenital Diaphragmatic Hernia Produce Common Lung Pathologies.

Donahoe PK, Longoni M, High FA.

Am J Pathol. 2016 Oct;186(10):2532-43. doi: 10.1016/j.ajpath.2016.07.006. Epub 2016 Aug 24. Review.

14.

Type IV collagen drives alveolar epithelial-endothelial association and the morphogenetic movements of septation.

Loscertales M, Nicolaou F, Jeanne M, Longoni M, Gould DB, Sun Y, Maalouf FI, Nagy N, Donahoe PK.

BMC Biol. 2016 Jul 13;14:59. doi: 10.1186/s12915-016-0281-2. Erratum in: BMC Biol. 2016;14:73.

15.

Anti-Müllerian Hormone Signaling Regulates Epithelial Plasticity and Chemoresistance in Lung Cancer.

Beck TN, Korobeynikov VA, Kudinov AE, Georgopoulos R, Solanki NR, Andrews-Hoke M, Kistner TM, Pépin D, Donahoe PK, Nicolas E, Einarson MB, Zhou Y, Boumber Y, Proia DA, Serebriiskii IG, Golemis EA.

Cell Rep. 2016 Jul 19;16(3):657-71. doi: 10.1016/j.celrep.2016.06.043. Epub 2016 Jul 7.

16.

De novo frameshift mutation in COUP-TFII (NR2F2) in human congenital diaphragmatic hernia.

High FA, Bhayani P, Wilson JM, Bult CJ, Donahoe PK, Longoni M.

Am J Med Genet A. 2016 Sep;170(9):2457-61. doi: 10.1002/ajmg.a.37830. Epub 2016 Jul 1.

17.

CD44 Splice Variant v8-10 as a Marker of Serous Ovarian Cancer Prognosis.

Sosulski A, Horn H, Zhang L, Coletti C, Vathipadiekal V, Castro CM, Birrer MJ, Nagano O, Saya H, Lage K, Donahoe PK, Pépin D.

PLoS One. 2016 Jun 2;11(6):e0156595. doi: 10.1371/journal.pone.0156595. eCollection 2016.

18.

Patterns of Müllerian Inhibiting Substance Type II and Candidate Type I Receptors in Epithelial Ovarian Cancer.

Basal E, Ayeni T, Zhang Q, Langstraat C, Donahoe PK, Pepin D, Yin X, Leof E, Cliby W.

Curr Mol Med. 2016;16(3):222-31.

19.

MiR-449a Affects Epithelial Proliferation during the Pseudoglandular and Canalicular Phases of Avian and Mammal Lung Development.

Sanford EL, Choy KW, Donahoe PK, Tracy AA, Hila R, Loscertales M, Longoni M.

PLoS One. 2016 Feb 18;11(2):e0149425. doi: 10.1371/journal.pone.0149425. eCollection 2016.

20.

AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer.

Pépin D, Sosulski A, Zhang L, Wang D, Vathipadiekal V, Hendren K, Coletti CM, Yu A, Castro CM, Birrer MJ, Gao G, Donahoe PK.

Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):E4418-27. doi: 10.1073/pnas.1510604112. Epub 2015 Jul 27.

21.

Transcriptome analysis reveals that Müllerian inhibiting substance regulates signaling pathways that contribute to endometrial carcinogenesis.

Chung YJ, Kim HJ, Park SH, Yoon JH, Kim MR, Nam SW, MacLaughlin DT, Donahoe PK, Kim JH.

Int J Oncol. 2015 May;46(5):2039-46. doi: 10.3892/ijo.2015.2920. Epub 2015 Mar 6.

22.

Müllerian inhibiting substance/anti-Müllerian hormone: A novel treatment for gynecologic tumors.

Kim JH, MacLaughlin DT, Donahoe PK.

Obstet Gynecol Sci. 2014 Sep;57(5):343-57. doi: 10.5468/ogs.2014.57.5.343. Epub 2014 Sep 17. Review.

23.

Molecular pathogenesis of congenital diaphragmatic hernia revealed by exome sequencing, developmental data, and bioinformatics.

Longoni M, High FA, Russell MK, Kashani A, Tracy AA, Coletti CM, Hila R, Shamia A, Wells J, Ackerman KG, Wilson JM, Bult CJ, Lee C, Lage K, Pober BR, Donahoe PK.

Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12450-5. doi: 10.1073/pnas.1412509111. Epub 2014 Aug 8.

24.

An albumin leader sequence coupled with a cleavage site modification enhances the yield of recombinant C-terminal Mullerian Inhibiting Substance.

Pépin D, Hoang M, Nicolaou F, Hendren K, Benedict LA, Al-Moujahed A, Sosulski A, Marmalidou A, Vavvas D, Donahoe PK.

Technology. 2013 Sep;1(1):63-71.

25.

Prevalence and penetrance of ZFPM2 mutations and deletions causing congenital diaphragmatic hernia.

Longoni M, Russell MK, High FA, Darvishi K, Maalouf FI, Kashani A, Tracy AA, Coletti CM, Loscertales M, Lage K, Ackerman KG, Woods SA, Ward-Melver C, Andrews D, Lee C, Pober BR, Donahoe PK.

Clin Genet. 2015 Apr;87(4):362-7. doi: 10.1111/cge.12395. Epub 2014 Apr 26.

26.

Induction of WNT inhibitory factor 1 expression by Müllerian inhibiting substance/antiMullerian hormone in the Müllerian duct mesenchyme is linked to Müllerian duct regression.

Park JH, Tanaka Y, Arango NA, Zhang L, Benedict LA, Roh MI, Donahoe PK, Teixeira JM.

Dev Biol. 2014 Feb 1;386(1):227-36. doi: 10.1016/j.ydbio.2013.12.015. Epub 2013 Dec 19.

27.

Meiosis I arrest abnormalities lead to severe oligozoospermia in meiosis 1 arresting protein (M1ap)-deficient mice.

Arango NA, Li L, Dabir D, Nicolau F, Pieretti-Vanmarcke R, Koehler C, McCarrey JR, Lu N, Donahoe PK.

Biol Reprod. 2013 Mar 28;88(3):76. doi: 10.1095/biolreprod.111.098673. Print 2013 Mar.

28.

Congenital diaphragmatic hernia interval on chromosome 8p23.1 characterized by genetics and protein interaction networks.

Longoni M, Lage K, Russell MK, Loscertales M, Abdul-Rahman OA, Baynam G, Bleyl SB, Brady PD, Breckpot J, Chen CP, Devriendt K, Gillessen-Kaesbach G, Grix AW, Rope AF, Shimokawa O, Strauss B, Wieczorek D, Zackai EH, Coletti CM, Maalouf FI, Noonan KM, Park JH, Tracy AA, Lee C, Donahoe PK, Pober BR.

Am J Med Genet A. 2012 Dec;158A(12):3148-58. doi: 10.1002/ajmg.a.35665. Epub 2012 Nov 19.

29.

Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development.

Lage K, Greenway SC, Rosenfeld JA, Wakimoto H, Gorham JM, Segrè AV, Roberts AE, Smoot LB, Pu WT, Pereira AC, Mesquita SM, Tommerup N, Brunak S, Ballif BC, Shaffer LG, Donahoe PK, Daly MJ, Seidman JG, Seidman CE, Larsen LA.

Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14035-40. doi: 10.1073/pnas.1210730109. Epub 2012 Aug 16.

30.

Mullerian inhibiting substance induces apoptosis of human endometrial stromal cells in endometriosis.

Namkung J, Song JY, Jo HH, Kim MR, Lew YO, Donahoe PK, MacLaughlin DT, Kim JH.

J Clin Endocrinol Metab. 2012 Sep;97(9):3224-30. doi: 10.1210/jc.2012-1538. Epub 2012 Jul 3.

31.

Expression of Müllerian inhibiting substance type II receptor and antiproliferative effects of MIS on human cervical cancer.

Song JY, Jo HH, Kim MR, Lew YO, Ryu KS, Cha JH, Kang CS, Donahoe PK, MacLaughlin DT, Kim JH.

Int J Oncol. 2012 Jun;40(6):2013-21. doi: 10.3892/ijo.2012.1370. Epub 2012 Feb 14.

32.

Congenital diaphragmatic hernia candidate genes derived from embryonic transcriptomes.

Russell MK, Longoni M, Wells J, Maalouf FI, Tracy AA, Loscertales M, Ackerman KG, Pober BR, Lage K, Bult CJ, Donahoe PK.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2978-83. doi: 10.1073/pnas.1121621109. Epub 2012 Feb 6.

33.

Human ovarian cancer stem/progenitor cells are stimulated by doxorubicin but inhibited by Mullerian inhibiting substance.

Meirelles K, Benedict LA, Dombkowski D, Pepin D, Preffer FI, Teixeira J, Tanwar PS, Young RH, MacLaughlin DT, Donahoe PK, Wei X.

Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2358-63. doi: 10.1073/pnas.1120733109. Epub 2012 Jan 27.

34.

Identification of characteristic molecular signature of Müllerian inhibiting substance in human HPV-related cervical cancer cells.

Hwang SJ, Suh MJ, Yoon JH, Kim MR, Ryu KS, Nam SW, Donahoe PK, Maclaughlin DT, Kim JH.

Int J Oncol. 2011 Oct;39(4):811-20. doi: 10.3892/ijo.2011.1042. Epub 2011 May 13.

35.

Comprehensive assessment of array-based platforms and calling algorithms for detection of copy number variants.

Pinto D, Darvishi K, Shi X, Rajan D, Rigler D, Fitzgerald T, Lionel AC, Thiruvahindrapuram B, Macdonald JR, Mills R, Prasad A, Noonan K, Gribble S, Prigmore E, Donahoe PK, Smith RS, Park JH, Hurles ME, Carter NP, Lee C, Scherer SW, Feuk L.

Nat Biotechnol. 2011 May 8;29(6):512-20. doi: 10.1038/nbt.1852.

36.

Müllerian inhibiting substance is anterogradely transported and does not attenuate avulsion-induced death of hypoglossal motor neurons.

Clarkson AN, Talbot CL, Wang PY, MacLaughlin DT, Donahoe PK, McLennan IS.

Exp Neurol. 2011 Oct;231(2):304-8. doi: 10.1016/j.expneurol.2010.12.019. Epub 2010 Dec 30.

37.

Mullerian inhibiting substance inhibits invasion and migration of epithelial cancer cell lines.

Chang HL, Pieretti-Vanmarcke R, Nicolaou F, Li X, Wei X, MacLaughlin DT, Donahoe PK.

Gynecol Oncol. 2011 Jan;120(1):128-34. doi: 10.1016/j.ygyno.2010.09.017. Epub 2010 Nov 6.

38.

Mullerian inhibiting substance preferentially inhibits stem/progenitors in human ovarian cancer cell lines compared with chemotherapeutics.

Wei X, Dombkowski D, Meirelles K, Pieretti-Vanmarcke R, Szotek PP, Chang HL, Preffer FI, Mueller PR, Teixeira J, MacLaughlin DT, Donahoe PK.

Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18874-9. doi: 10.1073/pnas.1012667107. Epub 2010 Oct 15.

39.

Focal Mullerian duct retention in male mice with constitutively activated beta-catenin expression in the Mullerian duct mesenchyme.

Tanwar PS, Zhang L, Tanaka Y, Taketo MM, Donahoe PK, Teixeira JM.

Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16142-7. doi: 10.1073/pnas.1011606107. Epub 2010 Aug 30.

40.

Characterization of the chromosome 1q41q42.12 region, and the candidate gene DISP1, in patients with CDH.

Kantarci S, Ackerman KG, Russell MK, Longoni M, Sougnez C, Noonan KM, Hatchwell E, Zhang X, Pieretti Vanmarcke R, Anyane-Yeboa K, Dickman P, Wilson J, Donahoe PK, Pober BR.

Am J Med Genet A. 2010 Oct;152A(10):2493-504. doi: 10.1002/ajmg.a.33618.

41.

Somatic stem cells of the ovary and their relationship to human ovarian cancers.

Chang HL, MacLaughlin DT, Donahoe PK.

StemBook [Internet]. Cambridge (MA): Harvard Stem Cell Institute; 2008-.
2009 Apr 30.

42.

Dissecting spatio-temporal protein networks driving human heart development and related disorders.

Lage K, Møllgård K, Greenway S, Wakimoto H, Gorham JM, Workman CT, Bendsen E, Hansen NT, Rigina O, Roque FS, Wiese C, Christoffels VM, Roberts AE, Smoot LB, Pu WT, Donahoe PK, Tommerup N, Brunak S, Seidman CE, Seidman JG, Larsen LA.

Mol Syst Biol. 2010 Jun 22;6:381. doi: 10.1038/msb.2010.36.

43.

Müllerian inhibiting substance/anti-Müllerian hormone: a potential therapeutic agent for human ovarian and other cancers.

MacLaughlin DT, Donahoe PK.

Future Oncol. 2010 Mar;6(3):391-405. doi: 10.2217/fon.09.172. Review.

44.

HOXB9, a gene overexpressed in breast cancer, promotes tumorigenicity and lung metastasis.

Hayashida T, Takahashi F, Chiba N, Brachtel E, Takahashi M, Godin-Heymann N, Gross KW, Vivanco Md, Wijendran V, Shioda T, Sgroi D, Donahoe PK, Maheswaran S.

Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1100-5. doi: 10.1073/pnas.0912710107. Epub 2009 Dec 28.

45.

Uterine leiomyomas exhibit fewer stem/progenitor cell characteristics when compared with corresponding normal myometrium.

Chang HL, Senaratne TN, Zhang L, Szotek PP, Stewart E, Dombkowski D, Preffer F, Donahoe PK, Teixeira J.

Reprod Sci. 2010 Feb;17(2):158-67. doi: 10.1177/1933719109348924. Epub 2009 Oct 5.

46.

Development of an efficiently cleaved, bioactive, highly pure FLAG-tagged recombinant human Mullerian Inhibiting Substance.

Papakostas TD, Pieretti-Vanmarcke R, Nicolaou F, Thanos A, Trichonas G, Koufomichali X, Anago K, Donahoe PK, Teixeira J, MacLaughlin DT, Vavvas D.

Protein Expr Purif. 2010 Mar;70(1):32-8. doi: 10.1016/j.pep.2009.09.004. Epub 2009 Sep 13.

47.

A pediatric surgeon retools in genetics and genomics to study congenital diaphragmatic hernia.

Donahoe PK.

J Pediatr Surg. 2009 Feb;44(2):307-11. doi: 10.1016/j.jpedsurg.2008.10.077.

48.

Genetic tools and algorithms for gene discovery in major congenital anomalies.

Donahoe PK, Noonan KM, Lage K.

Birth Defects Res A Clin Mol Teratol. 2009 Jan;85(1):6-12. doi: 10.1002/bdra.20546. No abstract available.

49.

A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes.

Lage K, Hansen NT, Karlberg EO, Eklund AC, Roque FS, Donahoe PK, Szallasi Z, Jensen TS, Brunak S.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20870-5. doi: 10.1073/pnas.0810772105. Epub 2008 Dec 22.

50.

Cell migration and activated PI3K/AKT-directed elongation in the developing rat Müllerian duct.

Fujino A, Arango NA, Zhan Y, Manganaro TF, Li X, MacLaughlin DT, Donahoe PK.

Dev Biol. 2009 Jan 15;325(2):351-62. doi: 10.1016/j.ydbio.2008.10.027. Epub 2008 Nov 5.

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