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Items: 44


A multicenter randomized, double-blind, placebo-controlled pilot study to assess the efficacy and safety of riociguat in systemic sclerosis-associated digital ulcers.

Nagaraja V, Spino C, Bush E, Tsou PS, Domsic RT, Lafyatis R, Frech T, Gordon JK, Steen VD, Khanna D.

Arthritis Res Ther. 2019 Sep 3;21(1):202. doi: 10.1186/s13075-019-1979-7.


Abatacept in Early Diffuse Cutaneous Systemic Sclerosis - Results of a Phase 2 Investigator-Initiated, Multicenter, Double-Blind Randomized Placebo-Controlled Trial.

Khanna D, Spino C, Johnson S, Chung L, Whitfield M, Denton CP, Berrocal V, Franks J, Mehta B, Molitor J, Steen VD, Lafyatis R, Simms RW, Gill A, Kafaja S, Frech TM, Hsu V, Domsic RT, Pope JE, Gordon JK, Mayes MD, Schiopu E, Young A, Sandorfi N, Park J, Hant FN, Bernstein EJ, Chatterjee S, Castelino FV, Ajam A, Wang Y, Wood T, Allanore Y, Matucci-Cerinic M, Distler O, Singer O, Bush E, Fox D, Furst DE.

Arthritis Rheumatol. 2019 Jul 24. doi: 10.1002/art.41055. [Epub ahead of print]


An Interim Report of the Scleroderma Clinical Trials Consortium Working Groups.

Baron M, Kahaleh B, Bernstein EJ, Chung L, Clements PJ, Denton C, Domsic RT, Ferdowsi N, Foeldvari I, Frech T, Gordon JK, Hudson M, Johnson SR, Khanna D, McMahan Z, Merkel PA, Narain S, Nikpour M, Pauling JD, Ross L, Valenzuela Vergara AM, Vacca A.

J Scleroderma Relat Disord. 2019 Feb;4(1):17-27. doi: 10.1177/2397198318783926. Epub 2018 Jul 18.


Pulmonary veno-occlusive disease is highly prevalent in scleroderma patients undergoing lung transplantation.

Gupta S, Gupta A, Rehman S, Ocak I, Domsic RT, Schneider F, George MP.

ERJ Open Res. 2019 Feb 11;5(1). pii: 00168-2018. doi: 10.1183/23120541.00168-2018. eCollection 2019 Feb.


Patient-reported outcome instruments for assessing Raynaud's phenomenon in systemic sclerosis: A SCTC Vascular Working Group Report.

Pauling JD, Frech TM, Hughes M, Gordon JK, Domsic RT, Anderson ME, Ingegnoli F, McHugh NJ, Johnson SR, Hudson M, Boin F, Ong VH, Matucci-Cerinic M, Altorok N, Scolnik M, Nikpour M, Shah A, Pope JE, Khanna D, Herrick AL.

J Scleroderma Relat Disord. 2018 Oct;3(3):249-252. doi: 10.1177/2397198318774307. Epub 2018 May 24.


Risk Factors for Mortality and Cardiopulmonary Hospitalization in Systemic Sclerosis Patients At Risk for Pulmonary Hypertension, in the PHAROS Registry.

Hsu VM, Chung L, Hummers LK, Shah A, Simms R, Bolster M, Hant FN, Silver RM, Fischer A, Hinchcliff ME, Varga J, Goldberg AZ, Derk CT, Schiopu E, Khanna D, Shapiro LS, Domsic RT, Medsger T, Mayes MD, Furst D, Csuka ME, Molitor JA, Saketkoo LA, Salazar CR, Steen VD.

J Rheumatol. 2019 Feb;46(2):176-183. doi: 10.3899/jrheum.180018. Epub 2018 Oct 1.


Anti-RNPC-3 (U11/U12) Antibodies in Systemic Sclerosis in Patients With Moderate-to-Severe Gastrointestinal Dysmotility.

McMahan ZH, Domsic RT, Zhu L, Medsger TA, Casciola-Rosen L, Shah AA.

Arthritis Care Res (Hoboken). 2019 Sep;71(9):1164-1170. doi: 10.1002/acr.23763. Epub 2019 Aug 6.


Brief Report: Whole-Exome Sequencing to Identify Rare Variants and Gene Networks That Increase Susceptibility to Scleroderma in African Americans.

Gourh P, Remmers EF, Boyden SE, Alexander T, Morgan ND, Shah AA, Mayes MD, Doumatey A, Bentley AR, Shriner D, Domsic RT, Medsger TA Jr, Steen VD, Ramos PS, Silver RM, Korman B, Varga J, Schiopu E, Khanna D, Hsu V, Gordon JK, Saketkoo LA, Gladue H, Kron B, Criswell LA, Derk CT, Bridges SL Jr, Shanmugam VK, Kolstad KD, Chung L, Jan R, Bernstein EJ, Goldberg A, Trojanowski M, Kafaja S, Maksimowicz-McKinnon KM, Mullikin JC, Adeyemo A, Rotimi C, Boin F, Kastner DL, Wigley FM.

Arthritis Rheumatol. 2018 Oct;70(10):1654-1660. doi: 10.1002/art.40541. Epub 2018 Aug 29.


Patient Perceptions of the Raynaud's Condition Score Diary Provide Insight Into Its Performance in Clinical Trials of Raynaud's Phenomenon: Comment on the Article by Denton et al.

Pauling JD, Saketkoo LA, Domsic RT.

Arthritis Rheumatol. 2018 Jun;70(6):973-974. doi: 10.1002/art.40481. Epub 2018 Apr 29. No abstract available.


Development of a Neo-Epitope Specific Assay for Serological Assessment of Type VII Collagen Turnover and Its Relevance in Fibroproliferative Disorders.

Sand JMB, Lamy P, Juhl P, Siebuhr AS, Iversen LV, Nawrocki A, Larsen MR, Domsic RT, Franchimont N, Chavez J, Karsdal MA, Leeming DJ.

Assay Drug Dev Technol. 2018 Feb/Mar;16(2):123-131. doi: 10.1089/adt.2017.820. Epub 2018 Mar 1.


Multinational Qualitative Research Study Exploring the Patient Experience of Raynaud's Phenomenon in Systemic Sclerosis.

Pauling JD, Domsic RT, Saketkoo LA, Almeida C, Withey J, Jay H, Frech TM, Ingegnoli F, Dures E, Robson J, McHugh NJ, Herrick AL, Matucci-Cerinic M, Khanna D, Hewlett S.

Arthritis Care Res (Hoboken). 2018 Sep;70(9):1373-1384. doi: 10.1002/acr.23475. Epub 2018 Aug 16.


Clinical and serological features of systemic sclerosis in a multicenter African American cohort: Analysis of the genome research in African American scleroderma patients clinical database.

Morgan ND, Shah AA, Mayes MD, Domsic RT, Medsger TA Jr, Steen VD, Varga J, Carns M, Ramos PS, Silver RM, Schiopu E, Khanna D, Hsu V, Gordon JK, Gladue H, Saketkoo LA, Criswell LA, Derk CT, Trojanowski MA, Shanmugam VK, Chung L, Valenzuela A, Jan R, Goldberg A, Remmers EF, Kastner DL, Wigley FM, Gourh P, Boin F.

Medicine (Baltimore). 2017 Dec;96(51):e8980. doi: 10.1097/MD.0000000000008980.


Impact of Radiation Therapy on Scleroderma and Cancer Outcomes in Scleroderma Patients With Breast Cancer.

Shah DJ, Hirpara R, Poelman CL, Woods A, Hummers LK, Wigley FM, Wright JL, Parekh A, Steen VD, Domsic RT, Shah AA.

Arthritis Care Res (Hoboken). 2018 Oct;70(10):1517-1524. doi: 10.1002/acr.23505.


Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma.

Sullivan KM, Goldmuntz EA, Keyes-Elstein L, McSweeney PA, Pinckney A, Welch B, Mayes MD, Nash RA, Crofford LJ, Eggleston B, Castina S, Griffith LM, Goldstein JS, Wallace D, Craciunescu O, Khanna D, Folz RJ, Goldin J, St Clair EW, Seibold JR, Phillips K, Mineishi S, Simms RW, Ballen K, Wener MH, Georges GE, Heimfeld S, Hosing C, Forman S, Kafaja S, Silver RM, Griffing L, Storek J, LeClercq S, Brasington R, Csuka ME, Bredeson C, Keever-Taylor C, Domsic RT, Kahaleh MB, Medsger T, Furst DE; SCOT Study Investigators.

N Engl J Med. 2018 Jan 4;378(1):35-47.


Pomalidomide in Patients with Interstitial Lung Disease due to Systemic Sclerosis: A Phase II, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study.

Hsu VM, Denton CP, Domsic RT, Furst DE, Rischmueller M, Stanislav M, Steen VD, Distler JHW, Korish S, Cooper A, Choi S, Schafer PH, Horan G, Hough DR.

J Rheumatol. 2018 Mar;45(3):405-410. doi: 10.3899/jrheum.161040. Epub 2017 Nov 1.


Patient participation in patient-reported outcome instrument development in systemic sclerosis.

Pauling JD, Frech TM, Domsic RT, Hudson M.

Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 106(4):184-192. Epub 2017 May 2. Review.


Reliability and Validity of the Tender and Swollen Joint Counts and the Modified Rodnan Skin Score in Early Diffuse Cutaneous Systemic Sclerosis: Analysis from the Prospective Registry of Early Systemic Sclerosis Cohort.

Gordon JK, Girish G, Berrocal VJ, Zhang M, Hatzis C, Assassi S, Bernstein EJ, Domsic RT, Hant FN, Hinchcliff M, Schiopu E, Steen VD, Frech TM, Khanna D.

J Rheumatol. 2017 Jun;44(6):791-794. doi: 10.3899/jrheum.160654. Epub 2017 Mar 15.


Skin-Resident Effector Memory CD8+CD28- T Cells Exhibit a Profibrotic Phenotype in Patients with Systemic Sclerosis.

Li G, Larregina AT, Domsic RT, Stolz DB, Medsger TA Jr, Lafyatis R, Fuschiotti P.

J Invest Dermatol. 2017 May;137(5):1042-1050. doi: 10.1016/j.jid.2016.11.037. Epub 2016 Dec 22.


Utility of B-type natriuretic peptides in the assessment of patients with systemic sclerosis-associated pulmonary hypertension in the PHAROS registry.

Chung L, Fairchild RM, Furst DE, Li S, Alkassab F, Bolster MB, Csuka ME, Derk CT, Domsic RT, Fischer A, Frech TM, Gomberg-Maitland M, Gordon JK, Hinchcliff M, Hsu V, Hummers LK, Khanna D, Medsger TAJ, Molitor JA, Preston IR, Schiopu E, Shapiro L, Hant F, Silver R, Simms R, Varga J, Steen VD, Zamanian RT.

Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 106(4):106-113. Epub 2016 Nov 10.



Domsic RT, Lucas M, Nihtyanova SI, Denton CP, Wisniewski SR, Fine MJ, Kwoh CK, Medsger TA Jr.

Arthritis Rheumatol. 2017 Jan;69(1):242. doi: 10.1002/art.39853. No abstract available.


Clinical Trial Design Issues in Systemic Sclerosis: an Update.

Gordon JK, Domsic RT.

Curr Rheumatol Rep. 2016 Jun;18(6):38. doi: 10.1007/s11926-016-0582-z. Review.


Sublingual Abnormalities in Systemic Sclerosis.

Frech TM, Pauling JD, Murtaugh MA, Kendall K, Domsic RT.

J Clin Rheumatol. 2016 Jan;22(1):19-21. doi: 10.1097/RHU.0000000000000339.


Derivation and External Validation of a Prediction Rule for Five-Year Mortality in Patients With Early Diffuse Cutaneous Systemic Sclerosis.

Domsic RT, Nihtyanova SI, Wisniewski SR, Fine MJ, Lucas M, Kwoh CK, Denton CP, Medsger TA Jr.

Arthritis Rheumatol. 2016 Apr;68(4):993-1003. doi: 10.1002/art.39490. Erratum in: Arthritis Rheumatol. 2016 Nov;68(11):2751.


Association Between Initial Oral Therapy and Outcomes in Systemic Sclerosis-Related Pulmonary Arterial Hypertension.

Lammi MR, Mathai SC, Saketkoo LA, Domsic RT, Bojanowski C, Furst DE, Steen VD; Pulmonary Hypertension Assessment and Recognition of Outcomes in Scleroderma Investigators.

Arthritis Rheumatol. 2016 Mar;68(3):740-8. doi: 10.1002/art.39478.


Endothelial dysfunction is present only in the microvasculature and microcirculation of early diffuse systemic sclerosis patients.

Domsic RT, Dezfulian C, Shoushtari A, Ivanco D, Kenny E, Kwoh CK, Medsger TA Jr, Champion HC.

Clin Exp Rheumatol. 2014 Nov-Dec;32(6 Suppl 86):S-154-60. Epub 2014 Nov 5.


Scleroderma: the role of serum autoantibodies in defining specific clinical phenotypes and organ system involvement.

Domsic RT.

Curr Opin Rheumatol. 2014 Nov;26(6):646-52. doi: 10.1097/BOR.0000000000000113. Review.


Development of pulmonary hypertension in a high-risk population with systemic sclerosis in the Pulmonary Hypertension Assessment and Recognition of Outcomes in Scleroderma (PHAROS) cohort study.

Hsu VM, Chung L, Hummers LK, Wigley F, Simms R, Bolster M, Silver R, Fischer A, Hinchcliff ME, Varga J, Goldberg AZ, Derk CT, Schiopu E, Khanna D, Shapiro LS, Domsic RT, Medsger T, Mayes MD, Furst D, Csuka ME, Molitor JA, Alkassab F, Steen VD.

Semin Arthritis Rheum. 2014 Aug;44(1):55-62. doi: 10.1016/j.semarthrit.2014.03.002. Epub 2014 Mar 5.


Localized scleroderma and regional inflammatory myopathy.

Zivković SA, Freiberg W, Lacomis D, Domsic RT, Medsger TA.

Neuromuscul Disord. 2014 May;24(5):425-30. doi: 10.1016/j.nmd.2014.01.012. Epub 2014 Feb 1.


Derivation and validation of a prediction rule for two-year mortality in early diffuse cutaneous systemic sclerosis.

Domsic RT, Nihtyanova SI, Wisniewski SR, Fine MJ, Lucas M, Kwoh CK, Denton CP, Medsger TA Jr.

Arthritis Rheumatol. 2014 Jun;66(6):1616-24. doi: 10.1002/art.38381.


Survival and predictors of mortality in systemic sclerosis-associated pulmonary arterial hypertension: outcomes from the pulmonary hypertension assessment and recognition of outcomes in scleroderma registry.

Chung L, Domsic RT, Lingala B, Alkassab F, Bolster M, Csuka ME, Derk C, Fischer A, Frech T, Furst DE, Gomberg-Maitland M, Hinchcliff M, Hsu V, Hummers LK, Khanna D, Medsger TA Jr, Molitor JA, Preston IR, Schiopu E, Shapiro L, Silver R, Simms R, Varga J, Gordon JK, Steen VD.

Arthritis Care Res (Hoboken). 2014 Mar;66(3):489-95. doi: 10.1002/acr.22121.


Treatment of early diffuse systemic sclerosis skin disease.

Frech TM, Shanmugam VK, Shah AA, Assassi S, Gordon JK, Hant FN, Hinchcliff ME, Steen V, Khanna D, Kayser C, Domsic RT.

Clin Exp Rheumatol. 2013 Mar-Apr;31(2 Suppl 76):166-71. Epub 2013 Jul 23. Review.


Significance of palpable tendon friction rubs in early diffuse cutaneous systemic sclerosis.

Doré A, Lucas M, Ivanco D, Medsger TA Jr, Domsic RT.

Arthritis Care Res (Hoboken). 2013 Aug;65(8):1385-9. doi: 10.1002/acr.21964.


A clinical and serologic comparison of African American and Caucasian patients with systemic sclerosis.

Steen V, Domsic RT, Lucas M, Fertig N, Medsger TA Jr.

Arthritis Rheum. 2012 Sep;64(9):2986-94. doi: 10.1002/art.34482.


Anti-PM-Scl antibody in patients with systemic sclerosis.

Koschik RW 2nd, Fertig N, Lucas MR, Domsic RT, Medsger TA Jr.

Clin Exp Rheumatol. 2012 Mar-Apr;30(2 Suppl 71):S12-6. Epub 2012 May 29.


Connective tissue diseases: Predicting death in SSc: planning and cooperation are needed.

Domsic RT, Medsger TA Jr.

Nat Rev Rheumatol. 2011 Oct 4;7(11):628-30. doi: 10.1038/nrrheum.2011.152. No abstract available.


Scleroderma renal crisis: a pathology perspective.

Batal I, Domsic RT, Medsger TA, Bastacky S.

Int J Rheumatol. 2010;2010:543704. doi: 10.1155/2010/543704. Epub 2010 Jul 28.


Reliability and validity of the delta finger-to-palm (FTP), a new measure of finger range of motion in systemic sclerosis.

Torok KS, Baker NA, Lucas M, Domsic RT, Boudreau R, Medsger TA Jr.

Clin Exp Rheumatol. 2010 Mar-Apr;28(2 Suppl 58):S28-36. Epub 2010 Jun 10.


Skin thickness progression rate: a predictor of mortality and early internal organ involvement in diffuse scleroderma.

Domsic RT, Rodriguez-Reyna T, Lucas M, Fertig N, Medsger TA Jr.

Ann Rheum Dis. 2011 Jan;70(1):104-9. doi: 10.1136/ard.2009.127621. Epub 2010 Aug 2. Erratum in: Ann Rheum Dis. 2011 Jul;70(7):1350.


Systemic lupus erythematosus, rheumatoid arthritis, and postarthroplasty mortality: a cross-sectional analysis from the nationwide inpatient sample.

Domsic RT, Lingala B, Krishnan E.

J Rheumatol. 2010 Jul;37(7):1467-72. doi: 10.3899/jrheum.091371. Epub 2010 May 15.


Anti-U11/U12 RNP antibodies in systemic sclerosis: a new serologic marker associated with pulmonary fibrosis.

Fertig N, Domsic RT, Rodriguez-Reyna T, Kuwana M, Lucas M, Medsger TA Jr, Feghali-Bostwick CA.

Arthritis Rheum. 2009 Jul 15;61(7):958-65. doi: 10.1002/art.24586.


Renal biopsy findings predicting outcome in scleroderma renal crisis.

Batal I, Domsic RT, Shafer A, Medsger TA Jr, Kiss LP, Randhawa P, Bastacky S.

Hum Pathol. 2009 Mar;40(3):332-40. doi: 10.1016/j.humpath.2008.08.001. Epub 2008 Oct 29.


Hormone therapy in systemic lupus erythematosus.

Domsic RT, Manzi S.

Curr Rheumatol Rep. 2005 Dec;7(6):455-6; discussion 456. No abstract available.


Ankle osteoarthritis scale.

Domsic RT, Saltzman CL.

Foot Ankle Int. 1998 Jul;19(7):466-71.


Foot and ankle research priority: report from the Research Council of the American Orthopaedic Foot and Ankle Society.

Saltzman CL, Domsic RT, Baumhauer JF, Deland JT, Gill LH, Hurwitz SR, Kitaoka HB, McClouskey LC, Porter D.

Foot Ankle Int. 1997 Jul;18(7):447-8. No abstract available.


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