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Items: 31

1.

TLR7 and TLR8 activate distinct pathways in monocytes during RNA virus infection.

de Marcken M, Dhaliwal K, Danielsen AC, Gautron AS, Dominguez-Villar M.

Sci Signal. 2019 Oct 29;12(605). pii: eaaw1347. doi: 10.1126/scisignal.aaw1347.

2.

AKT isoforms modulate Th1-like Treg generation and function in human autoimmune disease.

Kitz A, de Marcken M, Gautron AS, Mitrovic M, Hafler DA, Dominguez-Villar M.

EMBO Rep. 2019 Aug;20(8):e48624. doi: 10.15252/embr.201948624. No abstract available.

3.

Author Correction: Activated β-catenin in Foxp3+ regulatory T cells links inflammatory environments to autoimmunity.

Sumida T, Lincoln MR, Ukeje CM, Rodriguez DM, Akazawa H, Noda T, Naito AT, Komuro I, Dominguez-Villar M, Hafler DA.

Nat Immunol. 2019 Jul;20(7):943. doi: 10.1038/s41590-019-0438-6.

PMID:
31175348
4.

Corrigendum to "Fingolimod modulates T cell phenotype and regulatory T cell plasticity in vivo" [Yjaut 96C (2019) 40-49].

Dominguez-Villar M, Raddassi K, Danielsen AC, Guarnaccia J, Hafler DA.

J Autoimmun. 2019 Aug;102:179. doi: 10.1016/j.jaut.2019.05.008. Epub 2019 May 18. No abstract available.

PMID:
31109655
5.

TIGIT signaling restores suppressor function of Th1 Tregs.

Lucca LE, Axisa PP, Singer ER, Nolan NM, Dominguez-Villar M, Hafler DA.

JCI Insight. 2019 Feb 7;4(3). pii: 124427. doi: 10.1172/jci.insight.124427. [Epub ahead of print]

6.

Activated β-catenin in Foxp3+ regulatory T cells links inflammatory environments to autoimmunity.

Sumida T, Lincoln MR, Ukeje CM, Rodriguez DM, Akazawa H, Noda T, Naito AT, Komuro I, Dominguez-Villar M, Hafler DA.

Nat Immunol. 2018 Dec;19(12):1391-1402. doi: 10.1038/s41590-018-0236-6. Epub 2018 Oct 29. Erratum in: Nat Immunol. 2019 Jul;20(7):943.

7.

Fingolimod modulates T cell phenotype and regulatory T cell plasticity in vivo.

Dominguez-Villar M, Raddassi K, Danielsen AC, Guarnaccia J, Hafler DA.

J Autoimmun. 2019 Jan;96:40-49. doi: 10.1016/j.jaut.2018.08.002. Epub 2018 Aug 16. Erratum in: J Autoimmun. 2019 Aug;102:179.

8.

Interactions between tumor-associated macrophages and tumor cells in glioblastoma: unraveling promising targeted therapies.

Morisse MC, Jouannet S, Dominguez-Villar M, Sanson M, Idbaih A.

Expert Rev Neurother. 2018 Sep;18(9):729-737. doi: 10.1080/14737175.2018.1510321. Epub 2018 Aug 22. Review.

PMID:
30099909
9.

Regulatory T cells in autoimmune disease.

Dominguez-Villar M, Hafler DA.

Nat Immunol. 2018 Jul;19(7):665-673. doi: 10.1038/s41590-018-0120-4. Epub 2018 Jun 20. Review.

PMID:
29925983
10.

The PI3K/AKT signaling pathway in regulatory T-cell development, stability, and function.

Pompura SL, Dominguez-Villar M.

J Leukoc Biol. 2018 Jan 22. doi: 10.1002/JLB.2MIR0817-349R. [Epub ahead of print] Review.

PMID:
29357116
11.

Molecular mechanisms underlying Th1-like Treg generation and function.

Kitz A, Dominguez-Villar M.

Cell Mol Life Sci. 2017 Nov;74(22):4059-4075. doi: 10.1007/s00018-017-2569-y. Epub 2017 Jun 17. Review.

PMID:
28624966
12.

Immune modulation by the hepatitis C virus core protein.

Fernández-Ponce C, Dominguez-Villar M, Muñoz-Miranda JP, Arbulo-Echevarria MM, Litrán R, Aguado E, García-Cozar F.

J Viral Hepat. 2017 May;24(5):350-356. doi: 10.1111/jvh.12675. Epub 2017 Feb 2. Review.

PMID:
28092420
13.

AKT isoforms modulate Th1-like Treg generation and function in human autoimmune disease.

Kitz A, de Marcken M, Gautron AS, Mitrovic M, Hafler DA, Dominguez-Villar M.

EMBO Rep. 2016 Aug;17(8):1169-83. doi: 10.15252/embr.201541905. Epub 2016 Jun 16. Erratum in: EMBO Rep. 2019 Aug;20(8):e48624.

14.

Sensitivity of dendritic cells to NK-mediated lysis depends on the inflammatory environment and is modulated by CD54/CD226-driven interactions.

Smith LE, Olszewski MA, Georgoudaki AM, Wagner AK, Hägglöf T, Karlsson MC, Dominguez-Villar M, Garcia-Cozar F, Mueller S, Ravens I, Bernhardt G, Chambers BJ.

J Leukoc Biol. 2016 Oct;100(4):781-789. Epub 2016 Mar 31.

PMID:
27034402
15.

Nonapoptotic and extracellular activity of granzyme B mediates resistance to regulatory T cell (Treg) suppression by HLA-DR-CD25hiCD127lo Tregs in multiple sclerosis and in response to IL-6.

Bhela S, Kempsell C, Manohar M, Dominguez-Villar M, Griffin R, Bhatt P, Kivisakk-Webb P, Fuhlbrigge R, Kupper T, Weiner H, Baecher-Allan C.

J Immunol. 2015 Mar 1;194(5):2180-9. doi: 10.4049/jimmunol.1303257. Epub 2015 Jan 30.

16.

TLR7 induces anergy in human CD4(+) T cells.

Dominguez-Villar M, Gautron AS, de Marcken M, Keller MJ, Hafler DA.

Nat Immunol. 2015 Jan;16(1):118-28. doi: 10.1038/ni.3036. Epub 2014 Nov 17.

17.

Enhanced suppressor function of TIM-3+ FoxP3+ regulatory T cells.

Gautron AS, Dominguez-Villar M, de Marcken M, Hafler DA.

Eur J Immunol. 2014 Sep;44(9):2703-2711. doi: 10.1002/eji.201344392. Epub 2014 Jun 16.

18.

Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells.

Kofler DM, Marson A, Dominguez-Villar M, Xiao S, Kuchroo VK, Hafler DA.

J Clin Invest. 2014 Jun;124(6):2513-22. doi: 10.1172/JCI72973. Epub 2014 May 8.

19.

CD4+ primary T cells expressing HCV-core protein upregulate Foxp3 and IL-10, suppressing CD4 and CD8 T cells.

Fernandez-Ponce C, Dominguez-Villar M, Aguado E, Garcia-Cozar F.

PLoS One. 2014 Jan 20;9(1):e85191. doi: 10.1371/journal.pone.0085191. eCollection 2014.

20.

The TIGIT/CD226 axis regulates human T cell function.

Lozano E, Dominguez-Villar M, Kuchroo V, Hafler DA.

J Immunol. 2012 Apr 15;188(8):3869-75. doi: 10.4049/jimmunol.1103627. Epub 2012 Mar 16.

21.

Up-regulation of FOXP3 and induction of suppressive function in CD4+ Jurkat T-cells expressing hepatitis C virus core protein.

Dominguez-Villar M, Fernandez-Ponce C, Munoz-Suano A, Gomez E, Rodríguez-Iglesias M, Garcia-Cozar F.

Clin Sci (Lond). 2012 Jul;123(1):15-27. doi: 10.1042/CS20110631.

PMID:
22214248
22.

The effects of hepatitis C virus core protein on functional responses in the NK cell line YTS.

Dominguez-Villar M, Garcia-Cozar FJ, Chambers BJ.

Scand J Immunol. 2012 Jan;75(1):54-60. doi: 10.1111/j.1365-3083.2011.02624.x.

23.

Identification of T helper type 1-like, Foxp3+ regulatory T cells in human autoimmune disease.

Dominguez-Villar M, Baecher-Allan CM, Hafler DA.

Nat Med. 2011 Jun;17(6):673-5. doi: 10.1038/nm.2389. Epub 2011 May 3.

24.

Immunology. An innate role for IL-17.

Dominguez-Villar M, Hafler DA.

Science. 2011 Apr 1;332(6025):47-8. doi: 10.1126/science.1205311. No abstract available.

PMID:
21454778
25.

CD2 costimulation reveals defective activity by human CD4+CD25(hi) regulatory cells in patients with multiple sclerosis.

Baecher-Allan CM, Costantino CM, Cvetanovich GL, Ashley CW, Beriou G, Dominguez-Villar M, Hafler DA.

J Immunol. 2011 Mar 15;186(6):3317-26. doi: 10.4049/jimmunol.1002502. Epub 2011 Feb 7.

26.

Serine residues in the LAT adaptor are essential for TCR-dependent signal transduction.

Martínez-Florensa M, García-Blesa A, Yélamos J, Muñoz-Suano A, Domínguez-Villar M, Valdor R, Alonso A, García-Cózar F, Aparicio P, Malissen B, Aguado E.

J Leukoc Biol. 2011 Jan;89(1):63-73. doi: 10.1189/jlb.0509342. Epub 2010 Oct 12.

PMID:
20940326
27.

Droplet-based microfluidic platforms for single T cell secretion analysis of IL-10 cytokine.

Konry T, Dominguez-Villar M, Baecher-Allan C, Hafler DA, Yarmush ML.

Biosens Bioelectron. 2011 Jan 15;26(5):2707-10. doi: 10.1016/j.bios.2010.09.006. Epub 2010 Sep 15.

28.

Concurrent overexpression of serum p53 mutation related with Helicobacter pylori infection.

Lopez-Saez JB, Gómez-Biondi V, Santamaría-Rodriguez G, Dominguez-Villar M, Amaya-Vidal A, Lorenzo-Peñuelas A, Senra-Varela A.

J Exp Clin Cancer Res. 2010 Jun 4;29:65. doi: 10.1186/1756-9966-29-65.

29.

Metabolic profile of breast cancer in a population of women in southern Spain.

Lopez-Saez JB, Martinez-Rubio JA, Alvarez MM, Carrera CG, Dominguez Villar M, de Lomas Mier AG, Doménech C, Senra-Varela A.

Open Clin Cancer J. 2008 Jan 18;2:1-6. doi: 10.2174/1874189400802010001.

30.

Regulation of NFAT by poly(ADP-ribose) polymerase activity in T cells.

Valdor R, Schreiber V, Saenz L, Martínez T, Muñoz-Suano A, Dominguez-Villar M, Ramírez P, Parrilla P, Aguado E, García-Cózar F, Yélamos J.

Mol Immunol. 2008 Apr;45(7):1863-71.

PMID:
18078995
31.

Hepatitis C virus core protein up-regulates anergy-related genes and a new set of genes, which affects T cell homeostasis.

Domínguez-Villar M, Muñoz-Suano A, Anaya-Baz B, Aguilar S, Novalbos JP, Giron JA, Rodríguez-Iglesias M, Garcia-Cozar F.

J Leukoc Biol. 2007 Nov;82(5):1301-10. Epub 2007 Aug 21.

PMID:
17711976

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