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Items: 5


Increased SLC38A4 Amino Acid Transporter Expression in Human Pancreatic α-Cells After Glucagon Receptor Inhibition.

Kim J, Dominguez Gutierrez G, Xin Y, Cavino K, Sung B, Sipos B, Kloeppel G, Gromada J, Okamoto H.

Endocrinology. 2019 May 1;160(5):979-988. doi: 10.1210/en.2019-00022.


Gene Signature of the Human Pancreatic ε Cell.

Dominguez Gutierrez G, Kim J, Lee AH, Tong J, Niu J, Gray SM, Wei Y, Ding Y, Ni M, Adler C, Murphy AJ, Gromada J, Xin Y.

Endocrinology. 2018 Dec 1;159(12):4023-4032. doi: 10.1210/en.2018-00833.


Mice harboring the human SLC30A8 R138X loss-of-function mutation have increased insulin secretory capacity.

Kleiner S, Gomez D, Megra B, Na E, Bhavsar R, Cavino K, Xin Y, Rojas J, Dominguez-Gutierrez G, Zambrowicz B, Carrat G, Chabosseau P, Hu M, Murphy AJ, Yancopoulos GD, Rutter GA, Gromada J.

Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):E7642-E7649. doi: 10.1073/pnas.1721418115. Epub 2018 Jul 23.


Gene Signature of Proliferating Human Pancreatic α Cells.

Dominguez Gutierrez G, Xin Y, Okamoto H, Kim J, Lee AH, Ni M, Adler C, Yancopoulos GD, Murphy AJ, Gromada J.

Endocrinology. 2018 Sep 1;159(9):3177-3186. doi: 10.1210/en.2018-00469.


Pseudotime Ordering of Single Human β-Cells Reveals States of Insulin Production and Unfolded Protein Response.

Xin Y, Dominguez Gutierrez G, Okamoto H, Kim J, Lee AH, Adler C, Ni M, Yancopoulos GD, Murphy AJ, Gromada J.

Diabetes. 2018 Sep;67(9):1783-1794. doi: 10.2337/db18-0365. Epub 2018 Jun 27.

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