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Items: 10

1.

TET2 deficiency causes germinal center hyperplasia, impairs plasma cell differentiation and promotes B-cell lymphomagenesis.

Dominguez PM, Ghamlouch H, Rosikiewicz W, Kumar P, Béguelin W, Fontan L, Rivas MA, Pawlikowska P, Armand M, Mouly E, Torres-Martin M, Doane AS, Calvo Fernandez MT, Durant M, Della-Valle V, Teater M, Cimmino L, Droin N, Tadros S, Motanagh S, Shih AH, Rubin MA, Tam W, Aifantis I, Levine RL, Elemento O, Inghirami G, Green MR, Figueroa ME, Bernard OA, Aoufouchi S, Li S, Shaknovich R, Melnick AM.

Cancer Discov. 2018 Oct 1. pii: CD-18-0657. doi: 10.1158/2159-8290.CD-18-0657. [Epub ahead of print]

PMID:
30274972
2.

Extracellular vesicles in DLBCL provide abundant clues to aberrant transcriptional programming and genomic alterations.

Rutherford SC, Fachel AA, Li S, Sawh S, Muley A, Ishii J, Saxena A, Dominguez PM, Caldas Lopes E, Agirre X, Chambwe N, Correa F, Jiang Y, Richards KL, Betel D, Shaknovich R.

Blood. 2018 Aug 16;132(7):e13-e23. doi: 10.1182/blood-2017-12-821843. Epub 2018 Jul 2.

PMID:
29967128
3.

AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis.

Teater M, Dominguez PM, Redmond D, Chen Z, Ennishi D, Scott DW, Cimmino L, Ghione P, Chaudhuri J, Gascoyne RD, Aifantis I, Inghirami G, Elemento O, Melnick A, Shaknovich R.

Nat Commun. 2018 Jan 15;9(1):222. doi: 10.1038/s41467-017-02595-w.

4.

The new frontier of epigenetic heterogeneity in B-cell neoplasms.

Dominguez PM, Teater M, Shaknovich R.

Curr Opin Hematol. 2017 Jul;24(4):402-408. doi: 10.1097/MOH.0000000000000348. Review.

PMID:
28375986
5.

The many layers of epigenetic dysfunction in B-cell lymphomas.

Jiang Y, Dominguez PM, Melnick AM.

Curr Opin Hematol. 2016 Jul;23(4):377-84. doi: 10.1097/MOH.0000000000000249. Review.

PMID:
27055146
6.

DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID.

Dominguez PM, Teater M, Chambwe N, Kormaksson M, Redmond D, Ishii J, Vuong B, Chaudhuri J, Melnick A, Vasanthakumar A, Godley LA, Papavasiliou FN, Elemento O, Shaknovich R.

Cell Rep. 2015 Sep 29;12(12):2086-98. doi: 10.1016/j.celrep.2015.08.036. Epub 2015 Sep 10.

7.

Epigenetic function of activation-induced cytidine deaminase and its link to lymphomagenesis.

Dominguez PM, Shaknovich R.

Front Immunol. 2014 Dec 18;5:642. doi: 10.3389/fimmu.2014.00642. eCollection 2014. Review.

8.

IL-4 blocks TH1-polarizing/inflammatory cytokine gene expression during monocyte-derived dendritic cell differentiation through histone hypoacetylation.

López-Bravo M, Minguito de la Escalera M, Domínguez PM, González-Cintado L, del Fresno C, Martín P, Martínez del Hoyo G, Ardavín C.

J Allergy Clin Immunol. 2013 Dec;132(6):1409-19. doi: 10.1016/j.jaci.2013.08.039. Epub 2013 Oct 17.

PMID:
24139608
9.

Statins inhibit iNOS-mediated microbicidal potential of activated monocyte-derived dendritic cells by an IFN-β-dependent mechanism.

Domínguez PM, López-Bravo M, Kalinke U, Ardavín C.

Eur J Immunol. 2011 Nov;41(11):3330-9. doi: 10.1002/eji.201141674. Epub 2011 Oct 18.

10.

Differentiation and function of mouse monocyte-derived dendritic cells in steady state and inflammation.

Domínguez PM, Ardavín C.

Immunol Rev. 2010 Mar;234(1):90-104. doi: 10.1111/j.0105-2896.2009.00876.x. Review.

PMID:
20193014

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