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Items: 10


Loss of Kat2a enhances transcriptional noise and depletes acute myeloid leukemia stem-like cells.

Domingues AF, Kulkarni R, Giotopoulos G, Gupta S, Vinnenberg L, Arede L, Foerner E, Khalili M, Adao RR, Johns A, Tan S, Zeka K, Huntly BJ, Prabakaran S, Pina C.

Elife. 2020 Jan 27;9. pii: e51754. doi: 10.7554/eLife.51754.


Histone Acetyltransferase KAT2A Stabilizes Pluripotency with Control of Transcriptional Heterogeneity.

Moris N, Edri S, Seyres D, Kulkarni R, Domingues AF, Balayo T, Frontini M, Pina C.

Stem Cells. 2018 Dec;36(12):1828-1838. doi: 10.1002/stem.2919. Epub 2018 Oct 17.


A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.

Tzelepis K, Koike-Yusa H, De Braekeleer E, Li Y, Metzakopian E, Dovey OM, Mupo A, Grinkevich V, Li M, Mazan M, Gozdecka M, Ohnishi S, Cooper J, Patel M, McKerrell T, Chen B, Domingues AF, Gallipoli P, Teichmann S, Ponstingl H, McDermott U, Saez-Rodriguez J, Huntly BJP, Iorio F, Pina C, Vassiliou GS, Yusa K.

Cell Rep. 2016 Oct 18;17(4):1193-1205. doi: 10.1016/j.celrep.2016.09.079.


Calcium-permeable α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors trigger neuronal nitric-oxide synthase activation to promote nerve cell death in an Src kinase-dependent fashion.

Socodato R, Santiago FN, Portugal CC, Domingues AF, Santiago AR, Relvas JB, Ambrósio AF, Paes-de-Carvalho R.

J Biol Chem. 2012 Nov 9;287(46):38680-94. doi: 10.1074/jbc.M112.353961. Epub 2012 Sep 19.


Identification of new interacting partners for atypical Rho GTPases: a SILAC-based approach.

Montani L, Bausch-Fluck D, Domingues AF, Wollscheid B, Relvas JB.

Methods Mol Biol. 2012;827:305-17. doi: 10.1007/978-1-61779-442-1_20.


ER-mediated stress induces mitochondrial-dependent caspases activation in NT2 neuron-like cells.

Arduino DM, Esteves AR, Domingues AF, Pereira CM, Cardoso SM, Oliveira CR.

BMB Rep. 2009 Nov 30;42(11):719-24.


Monitoring of atmospheric ozone and nitrogen dioxide over the south of Portugal by ground-based and satellite observations.

Bortoli D, Silva AM, Costa MJ, Domingues AF, Giovanelli G.

Opt Express. 2009 Jul 20;17(15):12944-59.


Mitochondria and ubiquitin-proteasomal system interplay: relevance to Parkinson's disease.

Domingues AF, Arduíno DM, Esteves AR, Swerdlow RH, Oliveira CR, Cardoso SM.

Free Radic Biol Med. 2008 Sep 15;45(6):820-5. doi: 10.1016/j.freeradbiomed.2008.06.007. Epub 2008 Jun 12.


Mitochondrial function in Parkinson's disease cybrids containing an nt2 neuron-like nuclear background.

Esteves AR, Domingues AF, Ferreira IL, Januário C, Swerdlow RH, Oliveira CR, Cardoso SM.

Mitochondrion. 2008 Jun;8(3):219-28. doi: 10.1016/j.mito.2008.03.004. Epub 2008 Apr 6.


Calpain-mediated MPP+ toxicity in mitochondrial DNA depleted cells.

Domingues AF, Esteves AR, Swerdlow RH, Oliveira CR, Cardoso SM.

Neurotox Res. 2008 Jan;13(1):31-8.


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