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Items: 1 to 50 of 58

1.

Monozygotic twins with neuroblastoma MS have a similar molecular profile: a case of twin-to-twin metastasis.

Shatara M, Xavier AC, Dombkowski A, Cukovic D, Poulik JM, Altinok D, Ge Y, Taub JW.

Br J Cancer. 2019 Nov;121(10):890-893. doi: 10.1038/s41416-019-0594-3. Epub 2019 Oct 11.

PMID:
31601961
2.

Exposure of Larval Zebrafish to the Insecticide Propoxur Induced Developmental Delays that Correlate with Behavioral Abnormalities and Altered Expression of hspb9 and hspb11.

Shields JN, Hales EC, Ranspach LE, Luo X, Orr S, Runft D, Dombkowski A, Neely MN, Matherly LH, Taub J, Baker TR, Thummel R.

Toxics. 2019 Sep 21;7(4). pii: E50. doi: 10.3390/toxics7040050.

3.

TLR7 activation in epilepsy of tuberous sclerosis complex.

Dombkowski AA, Cukovic D, Bagla S, Jones M, Caruso JA, Chugani HT, Chugani DC.

Inflamm Res. 2019 Dec;68(12):993-998. doi: 10.1007/s00011-019-01283-3. Epub 2019 Sep 11.

4.

A nutrigenetic approach for investigating the chemopreventive effects of black raspberries during the development of preneoplastic esophagi in rats.

Pan P, Dombkowski AA, Wang LS, Stoner GD.

J Berry Res. 2018;8(4):263-274. doi: 10.3233/JBR-180346. Epub 2018 Dec 20.

5.

The extrema of circulating miR-17 are identified as biomarkers for aggressive prostate cancer.

Dyson G, Farran B, Bolton S, Craig DB, Dombkowski A, Beebe-Dimmer JL, Powell IJ, Podgorski I, Heilbrun LK, Bock CH.

Am J Cancer Res. 2018 Oct 1;8(10):2088-2095. eCollection 2018.

6.

Global Signaling Profiling in a Human Model of Tumorigenic Progression Indicates a Role for Alternative RNA Splicing in Cellular Reprogramming.

Caruso JA, Carruthers NJ, Thibodeau B, Geddes TJ, Dombkowski AA, Stemmer PM.

Int J Mol Sci. 2018 Sep 20;19(10). pii: E2847. doi: 10.3390/ijms19102847.

7.

Neuroinflammatory Nexus of Pediatric Epilepsy.

Bagla S, Dombkowski AA.

J Pediatr Epilepsy. 2018 Jun;7(2):32-39. doi: 10.1055/s-0038-1668601. Epub 2018 Sep 3.

8.

A study of circulating microRNAs identifies a new potential biomarker panel to distinguish aggressive prostate cancer.

Farran B, Dyson G, Craig D, Dombkowski A, Beebe-Dimmer JL, Powell IJ, Podgorski I, Heilbrun L, Bolton S, Bock CH.

Carcinogenesis. 2018 Apr 5;39(4):556-561. doi: 10.1093/carcin/bgy025.

9.

Challenges and recommendations for epigenomics in precision health.

Carter AC, Chang HY, Church G, Dombkowski A, Ecker JR, Gil E, Giresi PG, Greely H, Greenleaf WJ, Hacohen N, He C, Hill D, Ko J, Kohane I, Kundaje A, Palmer M, Snyder MP, Tung J, Urban A, Vidal M, Wong W.

Nat Biotechnol. 2017 Dec 8;35(12):1128-1132. doi: 10.1038/nbt.4030. No abstract available.

10.

A distinct microRNA expression profile is associated with α[11C]-methyl-L-tryptophan (AMT) PET uptake in epileptogenic cortical tubers resected from patients with tuberous sclerosis complex.

Bagla S, Cukovic D, Asano E, Sood S, Luat A, Chugani HT, Chugani DC, Dombkowski AA.

Neurobiol Dis. 2018 Jan;109(Pt A):76-87. doi: 10.1016/j.nbd.2017.10.004. Epub 2017 Oct 7.

11.

Black raspberries demethylate Sfrp4, a WNT pathway antagonist, in rat esophageal squamous cell papilloma.

Huang YW, Gu F, Dombkowski A, Wang LS, Stoner GD.

Mol Carcinog. 2016 Nov;55(11):1867-1875. doi: 10.1002/mc.22435. Epub 2015 Nov 19.

PMID:
27696538
12.

Gene Signature of High White Blood Cell Count in B-Precursor Acute Lymphoblastic Leukemia.

Edwards H, Rubenstein M, Dombkowski AA, Caldwell JT, Chu R, Xavier AC, Thummel R, Neely M, Matherly LH, Ge Y, Taub JW.

PLoS One. 2016 Aug 18;11(8):e0161539. doi: 10.1371/journal.pone.0161539. eCollection 2016.

13.

Differential Regulation of Gene Expression by Cholesterol Biosynthesis Inhibitors That Reduce (Pravastatin) or Enhance (Squalestatin 1) Nonsterol Isoprenoid Levels in Primary Cultured Mouse and Rat Hepatocytes.

Rondini EA, Duniec-Dmuchowski Z, Cukovic D, Dombkowski AA, Kocarek TA.

J Pharmacol Exp Ther. 2016 Aug;358(2):216-29. doi: 10.1124/jpet.116.233312. Epub 2016 May 25.

14.

Amplification of WHSC1L1 regulates expression and estrogen-independent activation of ERα in SUM-44 breast cancer cells and is associated with ERα over-expression in breast cancer.

Irish JC, Mills JN, Turner-Ivey B, Wilson RC, Guest ST, Rutkovsky A, Dombkowski A, Kappler CS, Hardiman G, Ethier SP.

Mol Oncol. 2016 Jun;10(6):850-65. doi: 10.1016/j.molonc.2016.02.003. Epub 2016 Feb 27.

15.

AP-2β Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development.

Chen L, Martino V, Dombkowski A, Williams T, West-Mays J, Gage PJ.

Invest Ophthalmol Vis Sci. 2016 Mar;57(3):1072-81. doi: 10.1167/iovs.15-18103.

16.

Upregulation of UGT2B4 Expression by 3'-Phosphoadenosine-5'-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid Conjugation.

Barrett KG, Fang H, Cukovic D, Dombkowski AA, Kocarek TA, Runge-Morris M.

Drug Metab Dispos. 2015 Jul;43(7):1061-70. doi: 10.1124/dmd.114.061440. Epub 2015 May 6.

17.

Cortical Tubers: Windows into Dysregulation of Epilepsy Risk and Synaptic Signaling Genes by MicroRNAs.

Dombkowski AA, Batista CE, Cukovic D, Carruthers NJ, Ranganathan R, Shukla U, Stemmer PM, Chugani HT, Chugani DC.

Cereb Cortex. 2016 Mar;26(3):1059-71. doi: 10.1093/cercor/bhu276. Epub 2014 Dec 1.

18.

A systems toxicology approach identifies Lyn as a key signaling phosphoprotein modulated by mercury in a B lymphocyte cell model.

Caruso JA, Stemmer PM, Dombkowski A, Caruthers NJ, Gill R, Rosenspire AJ.

Toxicol Appl Pharmacol. 2014 Apr 1;276(1):47-54. doi: 10.1016/j.taap.2014.01.002. Epub 2014 Jan 14.

19.

Protein disulfide engineering.

Dombkowski AA, Sultana KZ, Craig DB.

FEBS Lett. 2014 Jan 21;588(2):206-12. doi: 10.1016/j.febslet.2013.11.024. Epub 2013 Nov 26. Review.

20.

Disulfide by Design 2.0: a web-based tool for disulfide engineering in proteins.

Craig DB, Dombkowski AA.

BMC Bioinformatics. 2013 Dec 1;14:346. doi: 10.1186/1471-2105-14-346.

21.

Mercury alters B-cell protein phosphorylation profiles.

Caruthers NJ, Stemmer PM, Shin N, Dombkowski A, Caruso JA, Gill R, Rosenspire A.

J Proteome Res. 2014 Feb 7;13(2):496-505. doi: 10.1021/pr400657k. Epub 2013 Dec 4.

22.

A genomics-based analysis of relative potencies of dioxin-like compounds in primary rat hepatocytes.

Rowlands JC, Budinsky R, Gollapudi B, Black MB, Wolfinger RD, Cukovic D, Dombkowski A, Thompson CM, Urban JD, Thomas RS.

Toxicol Sci. 2013 Dec;136(2):595-604. doi: 10.1093/toxsci/kft203. Epub 2013 Sep 17.

PMID:
24046277
24.

Overexpression of GATA1 confers resistance to chemotherapy in acute megakaryocytic Leukemia.

Caldwell JT, Edwards H, Dombkowski AA, Buck SA, Matherly LH, Ge Y, Taub JW.

PLoS One. 2013 Jul 10;8(7):e68601. doi: 10.1371/journal.pone.0068601. Print 2013.

25.

Genomic amplification and a role in drug-resistance for the KDM5A histone demethylase in breast cancer.

Hou J, Wu J, Dombkowski A, Zhang K, Holowatyj A, Boerner JL, Yang ZQ.

Am J Transl Res. 2012;4(3):247-56. Epub 2012 Jul 22.

26.

Maspin reprograms the gene expression profile of prostate carcinoma cells for differentiation.

Bernardo MM, Meng Y, Lockett J, Dyson G, Dombkowski A, Kaplun A, Li X, Yin S, Dzinic S, Olive M, Dean I, Krass D, Moin K, Bonfil RD, Cher M, Sakr W, Sheng S.

Genes Cancer. 2011 Nov;2(11):1009-22. doi: 10.1177/1947601912440170.

27.

Augmented annotation and orthologue analysis for Oryctolagus cuniculus: Better Bunny.

Craig DB, Kannan S, Dombkowski AA.

BMC Bioinformatics. 2012 May 8;13:84. doi: 10.1186/1471-2105-13-84.

28.

Yeast IME2 functions early in meiosis upstream of cell cycle-regulated SBF and MBF targets.

Brush GS, Najor NA, Dombkowski AA, Cukovic D, Sawarynski KE.

PLoS One. 2012;7(2):e31575. doi: 10.1371/journal.pone.0031575. Epub 2012 Feb 29.

29.

Aging alters folate homeostasis and DNA damage response in colon.

Simon KW, Ma H, Dombkowski AA, Cabelof DC.

Mech Ageing Dev. 2012 Feb-Mar;133(2-3):75-82. doi: 10.1016/j.mad.2012.01.003. Epub 2012 Jan 25.

PMID:
22306610
30.

Cross-species comparisons of transcriptomic alterations in human and rat primary hepatocytes exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Black MB, Budinsky RA, Dombkowski A, Cukovic D, LeCluyse EL, Ferguson SS, Thomas RS, Rowlands JC.

Toxicol Sci. 2012 May;127(1):199-215. doi: 10.1093/toxsci/kfs069. Epub 2012 Feb 1.

PMID:
22298810
31.

A unique role of GATA1s in Down syndrome acute megakaryocytic leukemia biology and therapy.

Xavier AC, Edwards H, Dombkowski AA, Balci TB, Berman JN, Dellaire G, Xie C, Buck SA, Matherly LH, Ge Y, Taub JW.

PLoS One. 2011;6(11):e27486. doi: 10.1371/journal.pone.0027486. Epub 2011 Nov 16.

32.

Transcriptional profiling of human liver identifies sex-biased genes associated with polygenic dyslipidemia and coronary artery disease.

Zhang Y, Klein K, Sugathan A, Nassery N, Dombkowski A, Zanger UM, Waxman DJ.

PLoS One. 2011;6(8):e23506. doi: 10.1371/journal.pone.0023506. Epub 2011 Aug 12.

33.

Transcriptional profiles induced by the Aryl Hydrocarbon Receptor agonists 2,3,7,8-tetrachlorodibenzo-p-dioxin, 2,3,7,8-tetrachlorodibenzofuran and 2,3,4,7,8-pentachlorodibenzofuran in primary rat hepatocytes.

Rowlands JC, Budinsky R, Gollapudi B, Novak R, Abdelmegeed M, Cukovic D, Dombkowski A.

Chemosphere. 2011 Sep;85(2):232-8. doi: 10.1016/j.chemosphere.2011.06.026. Epub 2011 Jul 2.

PMID:
21724226
34.

Identification and functional analysis of 9p24 amplified genes in human breast cancer.

Wu J, Liu S, Liu G, Dombkowski A, Abrams J, Martin-Trevino R, Wicha MS, Ethier SP, Yang ZQ.

Oncogene. 2012 Jan 19;31(3):333-41. doi: 10.1038/onc.2011.227. Epub 2011 Jun 13.

35.

In silico analysis of combinatorial microRNA activity reveals target genes and pathways associated with breast cancer metastasis.

Dombkowski AA, Sultana Z, Craig DB, Jamil H.

Cancer Inform. 2011 Feb 17;10:13-29. doi: 10.4137/CIN.S6631.

36.

Mechanistic basis for the chemopreventive effects of black raspberries at a late stage of rat esophageal carcinogenesis.

Wang LS, Dombkowski AA, Seguin C, Rocha C, Cukovic D, Mukundan A, Henry C, Stoner GD.

Mol Carcinog. 2011 Apr;50(4):291-300. doi: 10.1002/mc.20634.

PMID:
21465577
37.

Microarray analysis of differentially regulated genes in human neuronal and epithelial cell lines upon exposure to type A botulinum neurotoxin.

Thirunavukkarasusx N, Ghosal KJ, Kukreja R, Zhou Y, Dombkowski A, Cai S, Singh BR.

Biochem Biophys Res Commun. 2011 Feb 25;405(4):684-90. doi: 10.1016/j.bbrc.2011.01.102. Epub 2011 Feb 1.

PMID:
21291863
38.

Folate deficiency provides protection against colon carcinogenesis in DNA polymerase beta haploinsufficient mice.

Ventrella-Lucente LF, Unnikrishnan A, Pilling AB, Patel HV, Kushwaha D, Dombkowski AA, Schmelz EM, Cabelof DC, Heydari AR.

J Biol Chem. 2010 Jun 18;285(25):19246-58. doi: 10.1074/jbc.M109.069807. Epub 2010 Apr 19.

39.

Intrinsic sex differences in the early growth hormone responsiveness of sex-specific genes in mouse liver.

Wauthier V, Sugathan A, Meyer RD, Dombkowski AA, Waxman DJ.

Mol Endocrinol. 2010 Mar;24(3):667-78. doi: 10.1210/me.2009-0454. Epub 2010 Feb 11.

40.

Transcriptional profiling of the age-related response to genotoxic stress points to differential DNA damage response with age.

Simon K, Mukundan A, Dewundara S, Van Remmen H, Dombkowski AA, Cabelof DC.

Mech Ageing Dev. 2009 Sep;130(9):637-47. doi: 10.1016/j.mad.2009.07.007. Epub 2009 Aug 11.

41.

RUNX1 regulates phosphoinositide 3-kinase/AKT pathway: role in chemotherapy sensitivity in acute megakaryocytic leukemia.

Edwards H, Xie C, LaFiura KM, Dombkowski AA, Buck SA, Boerner JL, Taub JW, Matherly LH, Ge Y.

Blood. 2009 Sep 24;114(13):2744-52. doi: 10.1182/blood-2008-09-179812. Epub 2009 Jul 28.

42.

Intestinal epithelial cells in vitro.

Chopra DP, Dombkowski AA, Stemmer PM, Parker GC.

Stem Cells Dev. 2010 Jan;19(1):131-42. doi: 10.1089/scd.2009.0109. Review.

43.

Effects of a black raspberry diet on gene expression in the rat esophagus.

Lechner JF, Reen RK, Dombkowski AA, Cukovic D, Salagrama S, Wang LS, Stoner GD.

Nutr Cancer. 2008;60 Suppl 1:61-9. doi: 10.1080/01635580802393118.

PMID:
19003582
44.

Global gene expression profiling unveils S100A8/A9 as candidate markers in H-ras-mediated human breast epithelial cell invasion.

Moon A, Yong HY, Song JI, Cukovic D, Salagrama S, Kaplan D, Putt D, Kim H, Dombkowski A, Kim HR.

Mol Cancer Res. 2008 Oct;6(10):1544-53. doi: 10.1158/1541-7786.MCR-08-0189.

45.

Carcinogen-altered genes in rat esophagus positively modulated to normal levels of expression by both black raspberries and phenylethyl isothiocyanate.

Stoner GD, Dombkowski AA, Reen RK, Cukovic D, Salagrama S, Wang LS, Lechner JF.

Cancer Res. 2008 Aug 1;68(15):6460-7. doi: 10.1158/0008-5472.CAN-08-0146.

46.

Liver-specific hepatocyte nuclear factor-4alpha deficiency: greater impact on gene expression in male than in female mouse liver.

Holloway MG, Miles GD, Dombkowski AA, Waxman DJ.

Mol Endocrinol. 2008 May;22(5):1274-86. doi: 10.1210/me.2007-0564. Epub 2008 Feb 14.

47.

The role of the proto-oncogene ETS2 in acute megakaryocytic leukemia biology and therapy.

Ge Y, LaFiura KM, Dombkowski AA, Chen Q, Payton SG, Buck SA, Salagrama S, Diakiw AE, Matherly LH, Taub JW.

Leukemia. 2008 Mar;22(3):521-9. Epub 2007 Dec 20.

48.

Effects of phenylethyl isothiocyanate on early molecular events in N-nitrosomethylbenzylamine-induced cytotoxicity in rat esophagus.

Reen RK, Dombkowski AA, Kresty LA, Cukovic D, Mele JM, Salagrama S, Nines R, Stoner GD.

Cancer Res. 2007 Jul 1;67(13):6484-92.

49.
50.

Construction and characterization of a t-PA mutant for use in ATTEMPTS: a drug delivery system for achieving targeted thrombolysis.

Yang VC, Naik SS, Song H, Dombkowski AA, Crippen G, Liang JF.

J Control Release. 2005 Dec 10;110(1):164-76. Epub 2005 Nov 2.

PMID:
16260060

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