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Items: 16


Pre-α-pro-GDNF and Pre-β-pro-GDNF Isoforms Are Neuroprotective in the 6-hydroxydopamine Rat Model of Parkinson's Disease.

Penttinen AM, Parkkinen I, Voutilainen MH, Koskela M, Bäck S, Their A, Richie CT, Domanskyi A, Harvey BK, Tuominen RK, Nevalaita L, Saarma M, Airavaara M.

Front Neurol. 2018 Jun 20;9:457. doi: 10.3389/fneur.2018.00457. eCollection 2018.


Can we treat neurodegenerative diseases by preventing an age-related decline in microRNA expression?

Vinnikov IA, Domanskyi A.

Neural Regen Res. 2017 Oct;12(10):1602-1604. doi: 10.4103/1673-5374.217328. No abstract available.


MANF Is Essential for Neurite Extension and Neuronal Migration in the Developing Cortex.

Tseng KY, Danilova T, Domanskyi A, Saarma M, Lindahl M, Airavaara M.

eNeuro. 2017 Sep 29;4(5). pii: ENEURO.0214-17.2017. doi: 10.1523/ENEURO.0214-17.2017. eCollection 2017 Sep-Oct.


MANF Promotes Differentiation and Migration of Neural Progenitor Cells with Potential Neural Regenerative Effects in Stroke.

Tseng KY, Anttila JE, Khodosevich K, Tuominen RK, Lindahl M, Domanskyi A, Airavaara M.

Mol Ther. 2018 Jan 3;26(1):238-255. doi: 10.1016/j.ymthe.2017.09.019. Epub 2017 Sep 21.


Pancreatic β-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF).

Cunha DA, Cito M, Grieco FA, Cosentino C, Danilova T, Ladrière L, Lindahl M, Domanskyi A, Bugliani M, Marchetti P, Eizirik DL, Cnop M.

J Biol Chem. 2017 Sep 8;292(36):14977-14988. doi: 10.1074/jbc.M116.769877. Epub 2017 Jul 11.


Dicer and microRNAs protect adult dopamine neurons.

Chmielarz P, Konovalova J, Najam SS, Alter H, Piepponen TP, Erfle H, Sonntag KC, Schütz G, Vinnikov IA, Domanskyi A.

Cell Death Dis. 2017 May 25;8(5):e2813. doi: 10.1038/cddis.2017.214.


Genetic mutations linked to Parkinson's disease differentially control nucleolar activity in pre-symptomatic mouse models.

Evsyukov V, Domanskyi A, Bierhoff H, Gispert S, Mustafa R, Schlaudraff F, Liss B, Parlato R.

Dis Model Mech. 2017 May 1;10(5):633-643. doi: 10.1242/dmm.028092. Epub 2017 Mar 30.


AAV Vector-Mediated Gene Delivery to Substantia Nigra Dopamine Neurons: Implications for Gene Therapy and Disease Models.

Albert K, Voutilainen MH, Domanskyi A, Airavaara M.

Genes (Basel). 2017 Feb 8;8(2). pii: E63. doi: 10.3390/genes8020063. Review.


Update of neurotrophic factors in neurobiology of addiction and future directions.

Koskela M, Bäck S, Võikar V, Richie CT, Domanskyi A, Harvey BK, Airavaara M.

Neurobiol Dis. 2017 Jan;97(Pt B):189-200. doi: 10.1016/j.nbd.2016.05.010. Epub 2016 May 14. Review.


Prospects of Neurotrophic Factors for Parkinson's Disease: Comparison of Protein and Gene Therapy.

Domanskyi A, Saarma M, Airavaara M.

Hum Gene Ther. 2015 Aug;26(8):550-9. doi: 10.1089/hum.2015.065. Review.


Transcription factors Foxa1 and Foxa2 are required for adult dopamine neurons maintenance.

Domanskyi A, Alter H, Vogt MA, Gass P, Vinnikov IA.

Front Cell Neurosci. 2014 Sep 9;8:275. doi: 10.3389/fncel.2014.00275. eCollection 2014.


Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models.

Domanskyi A, Geissler C, Vinnikov IA, Alter H, Schober A, Vogt MA, Gass P, Parlato R, Schütz G.

FASEB J. 2011 Sep;25(9):2898-910. doi: 10.1096/fj.11-181958. Epub 2011 May 18.


Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target of rapamycin signaling.

Rieker C, Engblom D, Kreiner G, Domanskyi A, Schober A, Stotz S, Neumann M, Yuan X, Grummt I, Schütz G, Parlato R.

J Neurosci. 2011 Jan 12;31(2):453-60. doi: 10.1523/JNEUROSCI.0590-10.2011.


An adenosine triphosphatase of the sucrose nonfermenting 2 family, androgen receptor-interacting protein 4, is essential for mouse embryonic development and cell proliferation.

Zhang FP, Domanskyi A, Palvimo JJ, Sariola H, Partanen J, Jänne OA.

Mol Endocrinol. 2007 Jun;21(6):1430-42. Epub 2007 Mar 20.


Expression and localization of androgen receptor-interacting protein-4 in the testis.

Domanskyi A, Zhang FP, Nurmio M, Palvimo JJ, Toppari J, Jänne OA.

Am J Physiol Endocrinol Metab. 2007 Feb;292(2):E513-22. Epub 2006 Sep 26.


Biochemical characterization of androgen receptor-interacting protein 4.

Domanskyi A, Virtanen KT, Palvimo JJ, Jänne OA.

Biochem J. 2006 Feb 1;393(Pt 3):789-95.

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