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Items: 50


Abrogation of EMILIN1-β1 integrin interaction promotes experimental colitis and colon carcinogenesis.

Capuano A, Pivetta E, Sartori G, Bosisio G, Favero A, Cover E, Andreuzzi E, Colombatti A, Cannizzaro R, Scanziani E, Minoli L, Bucciotti F, Amor Lopez AI, Gaspardo K, Doliana R, Mongiat M, Spessotto P.

Matrix Biol. 2019 Oct;83:97-115. doi: 10.1016/j.matbio.2019.08.006. Epub 2019 Aug 31.


Multiplex staining depicts the immune infiltrate in colitis-induced colon cancer model.

Pivetta E, Capuano A, Scanziani E, Minoli L, Andreuzzi E, Mongiat M, Baldassarre G, Doliana R, Spessotto P.

Sci Rep. 2019 Sep 2;9(1):12645. doi: 10.1038/s41598-019-49164-3.


Multimerin-2 maintains vascular stability and permeability.

Pellicani R, Poletto E, Andreuzzi E, Paulitti A, Doliana R, Bizzotto D, Braghetta P, Colladel R, Tarticchio G, Sabatelli P, Bucciotti F, Bressan G, Iozzo RV, Colombatti A, Bonaldo P, Mongiat M.

Matrix Biol. 2019 Aug 15. pii: S0945-053X(19)30295-1. doi: 10.1016/j.matbio.2019.08.002. [Epub ahead of print]


The Probe Based Confocal Laser Endomicroscopy (pCLE) in Locally Advanced Gastric Cancer: A Powerful Technique for Real-Time Analysis of Vasculature.

Capuano A, Andreuzzi E, Pivetta E, Doliana R, Favero A, Canzonieri V, Maiero S, Fornasarig M, Magris R, Cannizzaro R, Mongiat M, Spessotto P.

Front Oncol. 2019 Jun 13;9:513. doi: 10.3389/fonc.2019.00513. eCollection 2019.


Therapeutic decision based on molecular detection of resistance mechanism in an ALK-rearranged lung cancer patient: a case report.

De Carlo E, Schiappacassi M, Urbani M, Doliana R, Baldassarre G, Da Ros V, Santarossa S, Chimienti E, Berto E, Fratino L, Bearz A.

Onco Targets Ther. 2018 Dec 10;11:8945-8950. doi: 10.2147/OTT.S184745. eCollection 2018.


Loss of Multimerin-2 and EMILIN-2 Expression in Gastric Cancer Associate with Altered Angiogenesis.

Andreuzzi E, Capuano A, Pellicani R, Poletto E, Doliana R, Maiero S, Fornasarig M, Magris R, Colombatti A, Cannizzaro R, Spessotto P, Mongiat M.

Int J Mol Sci. 2018 Dec 11;19(12). pii: E3983. doi: 10.3390/ijms19123983.


Integrin binding site within the gC1q domain orchestrates EMILIN-1-induced lymphangiogenesis.

Capuano A, Pivetta E, Baldissera F, Bosisio G, Wassermann B, Bucciotti F, Colombatti A, Sabatelli P, Doliana R, Spessotto P.

Matrix Biol. 2019 Aug;81:34-49. doi: 10.1016/j.matbio.2018.10.006. Epub 2018 Oct 26.


A novel murine model for arrhythmogenic cardiomyopathy points to a pathogenic role of Wnt signalling and miRNA dysregulation.

Calore M, Lorenzon A, Vitiello L, Poloni G, Khan MAF, Beffagna G, Dazzo E, Sacchetto C, Polishchuk R, Sabatelli P, Doliana R, Carnevale D, Lembo G, Bonaldo P, De Windt L, Braghetta P, Rampazzo A.

Cardiovasc Res. 2019 Mar 15;115(4):739-751. doi: 10.1093/cvr/cvy253.


The ablation of the matricellular protein EMILIN2 causes defective vascularization due to impaired EGFR-dependent IL-8 production affecting tumor growth.

Paulitti A, Andreuzzi E, Bizzotto D, Pellicani R, Tarticchio G, Marastoni S, Pastrello C, Jurisica I, Ligresti G, Bucciotti F, Doliana R, Colladel R, Braghetta P, Poletto E, Di Silvestre A, Bressan G, Colombatti A, Bonaldo P, Mongiat M.

Oncogene. 2018 Jun;37(25):3399-3414. doi: 10.1038/s41388-017-0107-x. Epub 2018 Feb 27.


Acquired BRAF V600E Mutation as Resistant Mechanism after Treatment with Third-Generation EGFR Tyrosine Kinase Inhibitor.

Bearz A, De Carlo E, Doliana R, Schiappacassi M.

J Thorac Oncol. 2017 Nov;12(11):e181-e182. doi: 10.1016/j.jtho.2017.07.017. No abstract available.


The α4β1/EMILIN1 interaction discloses a novel and unique integrin-ligand type of engagement.

Capuano A, Fogolari F, Bucciotti F, Spessotto P, Nicolosi PA, Mucignat MT, Cervi M, Esposito G, Colombatti A, Doliana R.

Matrix Biol. 2018 Mar;66:50-66. doi: 10.1016/j.matbio.2017.10.001. Epub 2017 Oct 14.


Fibulin-4 deposition requires EMILIN-1 in the extracellular matrix of osteoblasts.

Schiavinato A, Keene DR, Imhof T, Doliana R, Sasaki T, Sengle G.

Sci Rep. 2017 Jul 17;7(1):5526. doi: 10.1038/s41598-017-05835-7.


The extracellular matrix protein EMILIN1 silences the RAS-ERK pathway via α4β1 integrin and decreases tumor cell growth.

Modica TME, Maiorani O, Sartori G, Pivetta E, Doliana R, Capuano A, Colombatti A, Spessotto P.

Oncotarget. 2017 Apr 18;8(16):27034-27046. doi: 10.18632/oncotarget.15067.


Neutrophil elastase cleavage of the gC1q domain impairs the EMILIN1-α4β1 integrin interaction, cell adhesion and anti-proliferative activity.

Maiorani O, Pivetta E, Capuano A, Modica TM, Wassermann B, Bucciotti F, Colombatti A, Doliana R, Spessotto P.

Sci Rep. 2017 Jan 11;7:39974. doi: 10.1038/srep39974.


Diagnostic Exome Sequencing Identifies a Novel Gene, EMILIN1, Associated with Autosomal-Dominant Hereditary Connective Tissue Disease.

Capuano A, Bucciotti F, Farwell KD, Tippin Davis B, Mroske C, Hulick PJ, Weissman SM, Gao Q, Spessotto P, Colombatti A, Doliana R.

Hum Mutat. 2016 Jan;37(1):84-97. doi: 10.1002/humu.22920. Epub 2015 Nov 4.


Multiple-interactions among EMILIN1 and EMILIN2 N- and C-terminal domains.

Bot S, Andreuzzi E, Capuano A, Schiavinato A, Colombatti A, Doliana R.

Matrix Biol. 2015 Jan;41:44-55. doi: 10.1016/j.matbio.2014.10.001. Epub 2014 Nov 1.


EMILIN1/α9β1 integrin interaction is crucial in lymphatic valve formation and maintenance.

Danussi C, Del Bel Belluz L, Pivetta E, Modica TM, Muro A, Wassermann B, Doliana R, Sabatelli P, Colombatti A, Spessotto P.

Mol Cell Biol. 2013 Nov;33(22):4381-94. doi: 10.1128/MCB.00872-13. Epub 2013 Sep 9.


The EMILIN/Multimerin family.

Colombatti A, Spessotto P, Doliana R, Mongiat M, Bressan GM, Esposito G.

Front Immunol. 2012 Jan 6;2:93. doi: 10.3389/fimmu.2011.00093. eCollection 2011.


NMR-based homology model for the solution structure of the C-terminal globular domain of EMILIN1.

Verdone G, Corazza A, Colebrooke SA, Cicero D, Eliseo T, Boyd J, Doliana R, Fogolari F, Viglino P, Colombatti A, Campbell ID, Esposito G.

J Biomol NMR. 2009 Feb;43(2):79-96. doi: 10.1007/s10858-008-9290-y. Epub 2008 Nov 21.


The solution structure of EMILIN1 globular C1q domain reveals a disordered insertion necessary for interaction with the alpha4beta1 integrin.

Verdone G, Doliana R, Corazza A, Colebrooke SA, Spessotto P, Bot S, Bucciotti F, Capuano A, Silvestri A, Viglino P, Campbell ID, Colombatti A, Esposito G.

J Biol Chem. 2008 Jul 4;283(27):18947-56. doi: 10.1074/jbc.M801085200. Epub 2008 May 7.


Emilin1 deficiency causes structural and functional defects of lymphatic vasculature.

Danussi C, Spessotto P, Petrucco A, Wassermann B, Sabatelli P, Montesi M, Doliana R, Bressan GM, Colombatti A.

Mol Cell Biol. 2008 Jun;28(12):4026-39. doi: 10.1128/MCB.02062-07. Epub 2008 Apr 14.


EMILINs interact with anthrax protective antigen and inhibit toxin action in vitro.

Doliana R, Veljkovic V, Prljic J, Veljkovic N, De Lorenzo E, Mongiat M, Ligresti G, Marastoni S, Colombatti A.

Matrix Biol. 2008 Mar;27(2):96-106. Epub 2007 Oct 10.


Regulation of the extrinsic apoptotic pathway by the extracellular matrix glycoprotein EMILIN2.

Mongiat M, Ligresti G, Marastoni S, Lorenzon E, Doliana R, Colombatti A.

Mol Cell Biol. 2007 Oct;27(20):7176-87. Epub 2007 Aug 13.


EMILIN1 represents a major stromal element determining human trophoblast invasion of the uterine wall.

Spessotto P, Bulla R, Danussi C, Radillo O, Cervi M, Monami G, Bossi F, Tedesco F, Doliana R, Colombatti A.

J Cell Sci. 2006 Nov 1;119(Pt 21):4574-84.


Sequence-specific backbone NMR assignments for the C-terminal globular domain of EMILIN-1.

Verdone G, Colebrooke SA, Boyd J, Viglino P, Corazza A, Doliana R, Mungiguerra G, Colombatti A, Esposito G, Campbell ID.

J Biomol NMR. 2004 May;29(1):91-2. No abstract available.


EMILIN-1 deficiency induces elastogenesis and vascular cell defects.

Zanetti M, Braghetta P, Sabatelli P, Mura I, Doliana R, Colombatti A, Volpin D, Bonaldo P, Bressan GM.

Mol Cell Biol. 2004 Jan;24(2):638-50.


beta 1 Integrin-dependent cell adhesion to EMILIN-1 is mediated by the gC1q domain.

Spessotto P, Cervi M, Mucignat MT, Mungiguerra G, Sartoretto I, Doliana R, Colombatti A.

J Biol Chem. 2003 Feb 21;278(8):6160-7. Epub 2002 Nov 26.


A novel bcl-1/JH breakpoint from a patient affected by mantle cell lymphoma extends the major translocation cluster.

Degan M, Doliana R, Gloghini A, Di Francia R, Aldinucci D, Mazzocut-Zecchin L, Colombatti A, Attadia V, Carbone A, Gattei V.

J Pathol. 2002 Jun;197(2):256-63.


Isolation and characterization of EMILIN-2, a new component of the growing EMILINs family and a member of the EMI domain-containing superfamily.

Doliana R, Bot S, Mungiguerra G, Canton A, Cilli SP, Colombatti A.

J Biol Chem. 2001 Apr 13;276(15):12003-11. Epub 2001 Jan 16.


Elastic fiber proteins in the glomerular mesangium in vivo and in cell culture.

Sterzel RB, Hartner A, Schlötzer-Schrehardt U, Voit S, Hausknecht B, Doliana R, Colombatti A, Gibson MA, Braghetta P, Bressan GM.

Kidney Int. 2000 Oct;58(4):1588-602.


The EMILIN protein family.

Colombatti A, Doliana R, Bot S, Canton A, Mongiat M, Mungiguerra G, Paron-Cilli S, Spessotto P.

Matrix Biol. 2000 Aug;19(4):289-301. Review.


Avian neural crest cell migration is diversely regulated by the two major hyaluronan-binding proteoglycans PG-M/versican and aggrecan.

Perissinotto D, Iacopetti P, Bellina I, Doliana R, Colombatti A, Pettway Z, Bronner-Fraser M, Shinomura T, Kimata K, Mörgelin M, Löfberg J, Perris R.

Development. 2000 Jul;127(13):2823-42.


Self-assembly and supramolecular organization of EMILIN.

Mongiat M, Mungiguerra G, Bot S, Mucignat MT, Giacomello E, Doliana R, Colombatti A.

J Biol Chem. 2000 Aug 18;275(33):25471-80.


Structure, chromosomal localization, and promoter analysis of the human elastin microfibril interfase located proteIN (EMILIN) gene.

Doliana R, Canton A, Bucciotti F, Mongiat M, Bonaldo P, Colombatti A.

J Biol Chem. 2000 Jan 14;275(2):785-92.


EMILIN, a component of the elastic fiber and a new member of the C1q/tumor necrosis factor superfamily of proteins.

Doliana R, Mongiat M, Bucciotti F, Giacomello E, Deutzmann R, Volpin D, Bressan GM, Colombatti A.

J Biol Chem. 1999 Jun 11;274(24):16773-81.


Identification of an active Chi recombinational hot spot within the HIV-1 envelope gene: consequences for development of AIDS vaccines.

Prljić J, Veljković N, Doliana R, Colombatti A, Johnson E, Metlas R, Veljković V.

Vaccine. 1999 Mar 17;17(11-12):1462-7.


Age-related persistent clonal expansions of CD28(-) cells: phenotypic and molecular TCR analysis reveals both CD4(+) and CD4(+)CD8(+) cells with identical CDR3 sequences.

Colombatti A, Doliana R, Schiappacassi M, Argentini C, Tonutti E, Feruglio C, Sala P.

Clin Immunol Immunopathol. 1998 Oct;89(1):61-70.


The human alpha3b is a 'full-sized' laminin chain variant with a more widespread tissue expression than the truncated alpha3a.

Doliana R, Bellina I, Bucciotti F, Mongiat M, Perris R, Colombatti A.

FEBS Lett. 1997 Nov 3;417(1):65-70.


Regulated expression of fibronectin, laminin and related integrin receptors during the early chondrocyte differentiation.

Tavella S, Bellese G, Castagnola P, Martin I, Piccini D, Doliana R, Colombatti A, Cancedda R, Tacchetti C.

J Cell Sci. 1997 Sep;110 ( Pt 18):2261-70.


The prolactin of European sea bass (Dicentrarchus labrax L.): cloning of cDNA and efficient expression in Escherichia coli.

Doliana R, Argentini C, Segat D, Santarossa P, Mucignat MT, Colombo L, Bortolussi M.

Biochem Mol Biol Int. 1994 Aug;33(6):1117-26.


Ovotransferrin and ovotransferrin receptor expression during chondrogenesis and endochondral bone formation in developing chick embryo.

Gentili C, Doliana R, Bet P, Campanile G, Colombatti A, Cancedda FD, Cancedda R.

J Cell Biol. 1994 Feb;124(4):579-88.


Structural and functional features of the alpha 3 chain indicate a bridging role for chicken collagen VI in connective tissues.

Bonaldo P, Russo V, Bucciotti F, Doliana R, Colombatti A.

Biochemistry. 1990 Feb 6;29(5):1245-54.


Changes in the organization of the extracellular matrix in ovarian follicles during the preovulatory phase and atresia. An immunofluorescence study.

Bortolussi M, Zanchetta R, Doliana R, Castellani I, Bressan GM, Lauria A.

Basic Appl Histochem. 1989;33(1):31-8.


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