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Items: 4


Drug treatment efficiency depends on the initial state of activation in nonlinear pathways.

Doldán-Martelli V, Míguez DG.

Sci Rep. 2018 Aug 21;8(1):12495. doi: 10.1038/s41598-018-30913-9.


Drug Resistance Mechanisms in Colorectal Cancer Dissected with Cell Type-Specific Dynamic Logic Models.

Eduati F, Doldàn-Martelli V, Klinger B, Cokelaer T, Sieber A, Kogera F, Dorel M, Garnett MJ, Blüthgen N, Saez-Rodriguez J.

Cancer Res. 2017 Jun 15;77(12):3364-3375. doi: 10.1158/0008-5472.CAN-17-0078. Epub 2017 Apr 5.


Synergistic interaction between selective drugs in cell populations models.

Doldán-Martelli V, Míguez DG.

PLoS One. 2015 Feb 11;10(2):e0117558. doi: 10.1371/journal.pone.0117558. eCollection 2015.


A mathematical model for the rational design of chimeric ligands in selective drug therapies.

Doldán-Martelli V, Guantes R, Míguez DG.

CPT Pharmacometrics Syst Pharmacol. 2013 Feb 13;2:e26. doi: 10.1038/psp.2013.2.

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