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Items: 43

1.

Inhibiting ex-vivo Th17 responses in Ankylosing Spondylitis by targeting Janus kinases.

Hammitzsch A, Chen L, de Wit J, Al-Mossawi MH, Ridley A, Sekine T, Simone D, Doig K, Skapenko A, Bowness P.

Sci Rep. 2018 Oct 23;8(1):15645. doi: 10.1038/s41598-018-34026-1.

2.

Exploring the feasibility and utility of exome-scale tumour sequencing in a clinical setting.

Lee B, Tran B, Hsu AL, Taylor GR, Fox SB, Fellowes A, Marquis R, Mooi J, Desai J, Doig K, Ekert P, Gaff C, Herath D, Hamilton A, James P, Roberts A, Snyder R, Waring P, McArthur G.

Intern Med J. 2018 Jul;48(7):786-794. doi: 10.1111/imj.13806.

PMID:
29607586
3.

Sensitive NPM1 Mutation Quantitation in Acute Myeloid Leukemia Using Ultradeep Next-Generation Sequencing in the Diagnostic Laboratory.

Blombery P, Jones K, Doig K, Ryland G, McBean M, Thompson E, Yannakou CK, Westerman D.

Arch Pathol Lab Med. 2018 May;142(5):606-612. doi: 10.5858/arpa.2017-0229-OA. Epub 2018 Feb 9.

PMID:
29425073
4.

Canary: an atomic pipeline for clinical amplicon assays.

Doig KD, Ellul J, Fellowes A, Thompson ER, Ryland G, Blombery P, Papenfuss AT, Fox SB.

BMC Bioinformatics. 2017 Dec 15;18(1):555. doi: 10.1186/s12859-017-1950-z.

5.

ASXL1 c.1934dup;p.Gly646Trpfs*12-a true somatic alteration requiring a new approach.

Yannakou CK, Jones K, McBean M, Thompson ER, Ryland GL, Doig K, Markham J, Westerman D, Blombery P.

Blood Cancer J. 2017 Dec 15;7(12):656. doi: 10.1038/s41408-017-0025-8. No abstract available.

6.

Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis.

Al-Mossawi MH, Chen L, Fang H, Ridley A, de Wit J, Yager N, Hammitzsch A, Pulyakhina I, Fairfax BP, Simone D, Yi Y, Bandyopadhyay S, Doig K, Gundle R, Kendrick B, Powrie F, Knight JC, Bowness P.

Nat Commun. 2017 Nov 15;8(1):1510. doi: 10.1038/s41467-017-01771-2.

7.

PathOS: a decision support system for reporting high throughput sequencing of cancers in clinical diagnostic laboratories.

Doig KD, Fellowes A, Bell AH, Seleznev A, Ma D, Ellul J, Li J, Doyle MA, Thompson ER, Kumar A, Lara L, Vedururu R, Reid G, Conway T, Papenfuss AT, Fox SB.

Genome Med. 2017 Apr 24;9(1):38. doi: 10.1186/s13073-017-0427-z.

8.

Reversion of BRCA1/2 Germline Mutations Detected in Circulating Tumor DNA From Patients With High-Grade Serous Ovarian Cancer.

Christie EL, Fereday S, Doig K, Pattnaik S, Dawson SJ, Bowtell DDL.

J Clin Oncol. 2017 Apr 20;35(12):1274-1280. doi: 10.1200/JCO.2016.70.4627. Epub 2017 Feb 13.

PMID:
28414925
9.

Circulating tumour DNA reflects treatment response and clonal evolution in chronic lymphocytic leukaemia.

Yeh P, Hunter T, Sinha D, Ftouni S, Wallach E, Jiang D, Chan YC, Wong SQ, Silva MJ, Vedururu R, Doig K, Lam E, Arnau GM, Semple T, Wall M, Zivanovic A, Agarwal R, Petrone P, Jones K, Westerman D, Blombery P, Seymour JF, Papenfuss AT, Dawson MA, Tam CS, Dawson SJ.

Nat Commun. 2017 Mar 17;8:14756. doi: 10.1038/ncomms14756.

10.

Clinicopathological differences exist between CALR- and JAK2-mutated myeloproliferative neoplasms despite a similar molecular landscape: data from targeted next-generation sequencing in the diagnostic laboratory.

Agarwal R, Blombery P, McBean M, Jones K, Fellowes A, Doig K, Forsyth C, Westerman DA.

Ann Hematol. 2017 May;96(5):725-732. doi: 10.1007/s00277-017-2937-6. Epub 2017 Feb 4.

PMID:
28161773
11.

Molecular disease monitoring using circulating tumor DNA in myelodysplastic syndromes.

Yeh P, Dickinson M, Ftouni S, Hunter T, Sinha D, Wong SQ, Agarwal R, Vedururu R, Doig K, Fong CY, Blombery P, Westerman D, Dawson MA, Dawson SJ.

Blood. 2017 Mar 23;129(12):1685-1690. doi: 10.1182/blood-2016-09-740308. Epub 2017 Jan 26.

12.

RORγt inhibitors suppress T(H)17 responses in inflammatory arthritis and inflammatory bowel disease.

de Wit J, Al-Mossawi MH, Hühn MH, Arancibia-Cárcamo CV, Doig K, Kendrick B, Gundle R, Taylor P, Mcclanahan T, Murphy E, Zhang H, Barr K, Miller JR, Hu X, Aicher TD, Morgan RW, Glick GD, Zaller D, Correll C, Powrie F, Bowness P.

J Allergy Clin Immunol. 2016 Mar;137(3):960-3. doi: 10.1016/j.jaci.2015.09.048. Epub 2015 Nov 21. No abstract available.

PMID:
26611672
13.

"Cancer 2015": A Prospective, Population-Based Cancer Cohort-Phase 1: Feasibility of Genomics-Guided Precision Medicine in the Clinic.

Parisot JP, Thorne H, Fellowes A, Doig K, Lucas M, McNeil JJ, Doble B, Dobrovic A, John T, James PA, Lipton L, Ashley D, Hayes T, McMurrick P, Richardson G, Lorgelly P, Fox SB, Thomas DM.

J Pers Med. 2015 Oct 29;5(4):354-69. doi: 10.3390/jpm5040354.

14.

Clinical cancer genomic analysis: data engineering required.

Doig K, Papenfuss AT, Fox S.

Lancet Oncol. 2015 Sep;16(9):1015-1017. doi: 10.1016/S1470-2045(15)00195-3. No abstract available.

PMID:
26370340
15.

Assessing the clinical value of targeted massively parallel sequencing in a longitudinal, prospective population-based study of cancer patients.

Wong SQ, Fellowes A, Doig K, Ellul J, Bosma TJ, Irwin D, Vedururu R, Tan AY, Weiss J, Chan KS, Lucas M, Thomas DM, Dobrovic A, Parisot JP, Fox SB.

Br J Cancer. 2015 Apr 14;112(8):1411-20. doi: 10.1038/bjc.2015.80. Epub 2015 Mar 5.

16.

Structural, optical and vibrational properties of self-assembled Pbn+1(Ti1-x Fex)nO(3n+1)-δ Ruddlesden-Popper superstructures.

Doig KI, Peters JJ, Nawaz S, Walker D, Walker M, Lees MR, Beanland R, Sanchez AM, McConville CF, Palkar VR, Lloyd-Hughes J.

Sci Rep. 2015 Jan 16;5:7719. doi: 10.1038/srep07719.

17.

Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing.

Wong SQ, Li J, Tan AY, Vedururu R, Pang JM, Do H, Ellul J, Doig K, Bell A, MacArthur GA, Fox SB, Thomas DM, Fellowes A, Parisot JP, Dobrovic A; CANCER 2015 Cohort.

BMC Med Genomics. 2014 May 13;7:23. doi: 10.1186/1755-8794-7-23.

18.

Studying cancer genomics through next-generation DNA sequencing and bioinformatics.

Doyle MA, Li J, Doig K, Fellowes A, Wong SQ.

Methods Mol Biol. 2014;1168:83-98. doi: 10.1007/978-1-4939-0847-9_6. Review.

PMID:
24870132
19.

High-temperature electromagnons in the magnetically induced multiferroic cupric oxide driven by intersublattice exchange.

Jones SP, Gaw SM, Doig KI, Prabhakaran D, Hétroy Wheeler EM, Boothroyd AT, Lloyd-Hughes J.

Nat Commun. 2014 Apr 29;5:3787. doi: 10.1038/ncomms4787.

PMID:
24777198
20.

Bioinformatics pipelines for targeted resequencing and whole-exome sequencing of human and mouse genomes: a virtual appliance approach for instant deployment.

Li J, Doyle MA, Saeed I, Wong SQ, Mar V, Goode DL, Caramia F, Doig K, Ryland GL, Thompson ER, Hunter SM, Halgamuge SK, Ellul J, Dobrovic A, Campbell IG, Papenfuss AT, McArthur GA, Tothill RW.

PLoS One. 2014 Apr 21;9(4):e95217. doi: 10.1371/journal.pone.0095217. eCollection 2014.

21.

Modifying the polarization state of terahertz radiation using anisotropic twin-domains in LaAlO₃.

Lloyd-Hughes J, Jones SP, Castro-Camus E, Doig KI, MacManus-Driscoll JL.

Opt Lett. 2014 Mar 1;39(5):1121-4. doi: 10.1364/OL.39.001121.

PMID:
24690686
22.

Massively-parallel sequencing assists the diagnosis and guided treatment of cancers of unknown primary.

Tothill RW, Li J, Mileshkin L, Doig K, Siganakis T, Cowin P, Fellowes A, Semple T, Fox S, Byron K, Kowalczyk A, Thomas D, Schofield P, Bowtell DD.

J Pathol. 2013 Dec;231(4):413-23. doi: 10.1002/path.4251.

PMID:
24037760
23.

Decreased vancomycin susceptibility in Staphylococcus aureus caused by IS256 tempering of WalKR expression.

McEvoy CR, Tsuji B, Gao W, Seemann T, Porter JL, Doig K, Ngo D, Howden BP, Stinear TP.

Antimicrob Agents Chemother. 2013 Jul;57(7):3240-9. doi: 10.1128/AAC.00279-13. Epub 2013 Apr 29.

24.

Host responses to persistent Mycobacterium avium subspecies paratuberculosis infection in surgically isolated bovine ileal segments.

Charavaryamath C, Gonzalez-Cano P, Fries P, Gomis S, Doig K, Scruten E, Potter A, Napper S, Griebel PJ.

Clin Vaccine Immunol. 2013 Feb;20(2):156-65. doi: 10.1128/CVI.00496-12. Epub 2012 Dec 5.

25.

Complete genome sequence of the frog pathogen Mycobacterium ulcerans ecovar Liflandii.

Tobias NJ, Doig KD, Medema MH, Chen H, Haring V, Moore R, Seemann T, Stinear TP.

J Bacteriol. 2013 Feb;195(3):556-64. doi: 10.1128/JB.02132-12. Epub 2012 Nov 30.

26.

Altered Toll-like receptor 9 signaling in Mycobacterium avium subsp. paratuberculosis-infected bovine monocytes reveals potential therapeutic targets.

Arsenault RJ, Li Y, Maattanen P, Scruten E, Doig K, Potter A, Griebel P, Kusalik A, Napper S.

Infect Immun. 2013 Jan;81(1):226-37. doi: 10.1128/IAI.00785-12. Epub 2012 Oct 31.

27.

On the origin of Mycobacterium ulcerans, the causative agent of Buruli ulcer.

Doig KD, Holt KE, Fyfe JA, Lavender CJ, Eddyani M, Portaels F, Yeboah-Manu D, Pluschke G, Seemann T, Stinear TP.

BMC Genomics. 2012 Jun 19;13:258. doi: 10.1186/1471-2164-13-258.

28.

Mycobacterium avium subsp. paratuberculosis inhibits gamma interferon-induced signaling in bovine monocytes: insights into the cellular mechanisms of Johne's disease.

Arsenault RJ, Li Y, Bell K, Doig K, Potter A, Griebel PJ, Kusalik A, Napper S.

Infect Immun. 2012 Sep;80(9):3039-48. doi: 10.1128/IAI.00406-12. Epub 2012 Jun 11.

29.

Mucosal changes in a long-term bovine intestinal segment model following removal of ingesta and microflora.

Charavaryamath C, Fries P, Gomis S, Bell C, Doig K, Guan LL, Potter A, Napper S, Griebel PJ.

Gut Microbes. 2011 May-Jun;2(3):134-44. doi: 10.4161/gmic.2.3.16483.

PMID:
21869606
30.

Are new CLS practitioners prepared to stay?

Beck S, Doig K.

Clin Lab Sci. 2007 Summer;20(3):161-71.

PMID:
17691672
31.

Referrals for movement disorder surgery: under-representation of females and reasons for refusal.

Setiawan M, Kraft S, Doig K, Hunka K, Haffenden A, Trew M, Longman S, Ranawaya R, Furtado S, Lee RG, Suchowersky O, Kiss ZH.

Can J Neurol Sci. 2006 Feb;33(1):53-7.

PMID:
16583722
32.

Laboratory managers' views on attrition and retention of laboratory personnel.

Beck S, Doig K.

Clin Lab Sci. 2005 Fall;18(4):238-47.

PMID:
16315742
33.

The case for the clinical doctorate in laboratory science.

Doig K.

Clin Lab Sci. 2005 Summer;18(3):132-6. No abstract available.

PMID:
16134472
34.

Factors contributing to the retention of clinical laboratory personnel.

Doig K, Beck S.

Clin Lab Sci. 2005 Winter;18(1):16-27.

PMID:
15747783
35.

The Canadian multicenter trial of pallidal deep brain stimulation for cervical dystonia: preliminary results in three patients.

Kiss ZH, Doig K, Eliasziw M, Ranawaya R, Suchowersky O.

Neurosurg Focus. 2004 Jul 15;17(1):E5.

PMID:
15264774
36.

An entry-level MS degree in clinical laboratory science: is it time?

Beck SJ, Doig K.

Clin Lab Sci. 2002 Summer;15(3):167-76.

PMID:
12778963
37.

CLS competencies expected at entry-level and beyond.

Beck SJ, Doig K.

Clin Lab Sci. 2002 Fall;15(4):220-8.

PMID:
12776782
38.

CLT and CLS job responsibilities: current distinctions and updates.

Doig K, Beck SJ, Kolenc K.

Clin Lab Sci. 2001 Summer;14(3):173-82.

PMID:
11517628
39.

Re-engineering the role and education of clinical laboratory scientists.

Doig K.

Clin Lab Sci. 2000 Winter;13(1):12-5. No abstract available.

PMID:
10788257
40.

The Child Development Inventory: A developmental outcome measure for follow-up of the high-risk infant.

Doig KB, Macias MM, Saylor CF, Craver JR, Ingram PE.

J Pediatr. 1999 Sep;135(3):358-62.

PMID:
10484803
41.

Teaching of pathology in United States medical schools, 1996/1997 survey.

Kumar K, Daniel J, Doig K, Agamanolis D.

Hum Pathol. 1998 Jul;29(7):750-5.

PMID:
9670834
42.
43.

Program review for instructor reflection and curriculum coherence.

Bridgham R, Doig K, Hoppe R.

Acad Med. 1994 May;69(5):409. No abstract available.

PMID:
8086048

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