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Items: 1 to 50 of 219

1.

A multicentre controlled pre-post trial of an implementation science intervention to improve venous thromboembolism prophylaxis in critically ill patients.

Stelfox HT, Brundin-Mather R, Soo A, Parsons Leigh J, Niven DJ, Fiest KM, Doig CJ, Zuege DJ, Kushner B, Clement F, Straus SE, Cook DJ, Bagshaw SM, Sauro KM.

Intensive Care Med. 2019 Feb;45(2):211-222. doi: 10.1007/s00134-019-05532-1. Epub 2019 Feb 1.

PMID:
30707246
2.

Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD + depletion.

Oakey LA, Fletcher RS, Elhassan YS, Cartwright DM, Doig CL, Garten A, Thakker A, Maddocks ODK, Zhang T, Tennant DA, Ludwig C, Lavery GG.

Wellcome Open Res. 2018 Nov 15;3:147. doi: 10.12688/wellcomeopenres.14898.1. eCollection 2018.

3.

Improving the adoption of optimal venous thromboembolism prophylaxis in critically ill patients: A process evaluation of a complex quality improvement initiative.

Sauro KM, Brundin-Mather R, Parsons Leigh J, Niven DJ, Kushner B, Soo A, Cook DJ, Straus S, Doig CJ, Bagshaw S, Stelfox HT.

J Crit Care. 2019 Apr;50:111-117. doi: 10.1016/j.jcrc.2018.11.023. Epub 2018 Nov 29.

PMID:
30529419
4.

Outcomes of selective nonoperative management of civilian abdominal gunshot wounds: a systematic review and meta-analysis.

Al Rawahi AN, Al Hinai FA, Boyd JM, Doig CJ, Ball CG, Velmahos GC, Kirkpatrick AW, Navsaria PH, Roberts DJ.

World J Emerg Surg. 2018 Nov 27;13:55. doi: 10.1186/s13017-018-0215-0. eCollection 2018.

5.

Secondary EMR data for quality improvement and research: A comparison of manual and electronic data collection from an integrated critical care electronic medical record system.

Brundin-Mather R, Soo A, Zuege DJ, Niven DJ, Fiest K, Doig CJ, Zygun D, Boyd JM, Parsons Leigh J, Bagshaw SM, Stelfox HT.

J Crit Care. 2018 Oct;47:295-301. doi: 10.1016/j.jcrc.2018.07.021. Epub 2018 Jul 22.

PMID:
30099330
6.

Closed Or Open after Source Control Laparotomy for Severe Complicated Intra-Abdominal Sepsis (the COOL trial): study protocol for a randomized controlled trial.

Kirkpatrick AW, Coccolini F, Ansaloni L, Roberts DJ, Tolonen M, McKee JL, Leppaniemi A, Faris P, Doig CJ, Catena F, Fabian T, Jenne CN, Chiara O, Kubes P, Manns B, Kluger Y, Fraga GP, Pereira BM, Diaz JJ, Sugrue M, Moore EE, Ren J, Ball CG, Coimbra R, Balogh ZJ, Abu-Zidan FM, Dixon E, Biffl W, MacLean A, Ball I, Drover J, McBeth PB, Posadas-Calleja JG, Parry NG, Di Saverio S, Ordonez CA, Xiao J, Sartelli M; Closed Or Open after Laparotomy (COOL) after Source Control for Severe Complicated Intra-Abdominal Sepsis Investigators.

World J Emerg Surg. 2018 Jun 22;13:26. doi: 10.1186/s13017-018-0183-4. eCollection 2018.

7.

Derivation of a PIRO Score for Prediction of Mortality in Surgical Patients With Intra-Abdominal Sepsis.

Posadas-Calleja JG, Stelfox HT, Ferland A, Zuege DJ, Niven DJ, Berthiaume L, Doig CJ.

Am J Crit Care. 2018 Jul;27(4):287-294. doi: 10.4037/ajcc2018576.

PMID:
29961664
8.

Nicotinamide Nucleotide Transhydrogenase as a Novel Treatment Target in Adrenocortical Carcinoma.

Chortis V, Taylor AE, Doig CL, Walsh MD, Meimaridou E, Jenkinson C, Rodriguez-Blanco G, Ronchi CL, Jafri A, Metherell LA, Hebenstreit D, Dunn WB, Arlt W, Foster PA.

Endocrinology. 2018 Aug 1;159(8):2836-2849. doi: 10.1210/en.2018-00014.

9.

Targeting inflammatory monocytes in sepsis-associated encephalopathy and long-term cognitive impairment.

Andonegui G, Zelinski EL, Schubert CL, Knight D, Craig LA, Winston BW, Spanswick SC, Petri B, Jenne CN, Sutherland JC, Nguyen R, Jayawardena N, Kelly MM, Doig CJ, Sutherland RJ, Kubes P.

JCI Insight. 2018 May 3;3(9). pii: 99364. doi: 10.1172/jci.insight.99364. [Epub ahead of print]

10.

Getting the invite list right: a discussion of sepsis severity scoring systems in severe complicated intra-abdominal sepsis and randomized trial inclusion criteria.

Tolonen M, Coccolini F, Ansaloni L, Sartelli M, Roberts DJ, McKee JL, Leppaniemi A, Doig CJ, Catena F, Fabian T, Jenne CN, Chiara O, Kubes P, Kluger Y, Fraga GP, Pereira BM, Diaz JJ, Sugrue M, Moore EE, Ren J, Ball CG, Coimbra R, Dixon E, Biffl W, MacLean A, McBeth PB, Posadas-Calleja JG, Di Saverio S, Xiao J, Kirkpatrick AW; From the Closed Or Open after Laparotomy (COOL) for Source Control in Severe Complicated Intra-Abdominal Sepsis Investigators.

World J Emerg Surg. 2018 Apr 6;13:17. doi: 10.1186/s13017-018-0177-2. eCollection 2018.

11.

Intentional overdose of liraglutide in a non-diabetic patient causing severe hypoglycemia.

Solverson KJ, Lee H, Doig CJ.

CJEM. 2018 Oct;20(S2):S61-S63. doi: 10.1017/cem.2017.439. Epub 2018 Feb 5.

PMID:
29397808
12.

Identifying What Is Known About Improving Operating Room to Intensive Care Handovers: A Scoping Review.

Zjadewicz K, Deemer KS, Coulthard J, Doig CJ, Boiteau PJ.

Am J Med Qual. 2018 Sep/Oct;33(5):540-548. doi: 10.1177/1062860618754701. Epub 2018 Jan 27.

PMID:
29374964
13.

Critical Care Organizations: Building and Integrating Academic Programs.

Moore JE, Oropello JM, Stoltzfus D, Masur H, Coopersmith CM, Nates J, Doig C, Christman J, Hite RD, Angus DC, Pastores SM, Kvetan V; Academic Leaders in Critical Care Medicine (ALCCM) Task Force of the Society of the Critical Care Medicine.

Crit Care Med. 2018 Apr;46(4):e334-e341. doi: 10.1097/CCM.0000000000002917.

PMID:
29256894
14.

Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion.

Fine NHF, Doig CL, Elhassan YS, Vierra NC, Marchetti P, Bugliani M, Nano R, Piemonti L, Rutter GA, Jacobson DA, Lavery GG, Hodson DJ.

Diabetes. 2018 Feb;67(2):278-290. doi: 10.2337/db16-1356. Epub 2017 Dec 4.

15.

Withholding and withdrawing life support: difficult decisions around care at the end of life.

Solverson KJ, Roze des Ordons AL, Doig CJ.

Can J Anaesth. 2018 Jan;65(1):9-13. doi: 10.1007/s12630-017-1001-2. Epub 2017 Nov 30. No abstract available.

PMID:
29192394
16.

The effectiveness of prehospital hypertonic saline for hypotensive trauma patients: a systematic review and meta-analysis.

Blanchard IE, Ahmad A, Tang KL, Ronksley PE, Lorenzetti D, Lazarenko G, Lang ES, Doig CJ, Stelfox HT.

BMC Emerg Med. 2017 Nov 28;17(1):35. doi: 10.1186/s12873-017-0146-1. Review.

17.

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells.

Fletcher RS, Ratajczak J, Doig CL, Oakey LA, Callingham R, Da Silva Xavier G, Garten A, Elhassan YS, Redpath P, Migaud ME, Philp A, Brenner C, Canto C, Lavery GG.

Mol Metab. 2017 May 29;6(8):819-832. doi: 10.1016/j.molmet.2017.05.011. eCollection 2017 Aug.

18.

Cellular and genetic models of H6PDH and 11β-HSD1 function in skeletal muscle.

Zielinska AE, Fletcher RS, Sherlock M, Doig CL, Lavery GG.

Cell Biochem Funct. 2017 Jul;35(5):269-277. doi: 10.1002/cbf.3272.

19.

Erratum to: Working memory, reasoning, and expertise in medicine-insights into their relationship using functional neuroimaging.

Hruska P, Krigolson O, Coderre S, McLaughlin K, Cortese F, Doig C, Beran T, Wright B, Hecker KG.

Adv Health Sci Educ Theory Pract. 2017 Oct;22(4):1049. doi: 10.1007/s10459-017-9786-x. No abstract available.

PMID:
28744826
20.

Erratum to: Hemispheric activation differences in novice and expert clinicians during clinical decision making.

Hruska P, Hecker KG, Coderre S, McLaughlin K, Cortese F, Doig C, Beran T, Wright B, Krigolson O.

Adv Health Sci Educ Theory Pract. 2017 Oct;22(4):1047. doi: 10.1007/s10459-017-9787-9. No abstract available.

PMID:
28744825
21.

Refractory Longitudinally Extensive Transverse Myelitis Responsive to Cyclophosphamide.

Baxter LJ, Chen S, Couillard P, Scott JN, Doig CJ, Costello F, Girard LP, Klassen J, Burton JM.

Can J Neurol Sci. 2017 Nov;44(6):736-739. doi: 10.1017/cjn.2017.201. Epub 2017 Jul 20.

PMID:
28724464
22.

A fatal case of pneumococcal sepsis years after splenectomy.

Solverson KJ, Doig CJ.

CMAJ. 2017 Jun 12;189(23):E800-E802. doi: 10.1503/cmaj.160455. No abstract available.

23.

The association between platelet transfusions and bleeding in critically ill patients with thrombocytopenia.

Arnold DM, Lauzier F, Albert M, Williamson D, Li N, Zarychanski R, Doig C, McIntyre L, Freitag A, Crowther M, Saunders L, Clarke F, Bellomo R, Qushmaq I, Lopes RD, Heels-Ansdell D, Webert K, Cook D; PROTECT Investigators, the Canadian Critical Care Trials Group and the Australian and New Zealand Intensive Care Society Clinical Trials Group.

Res Pract Thromb Haemost. 2017 May 31;1(1):103-111. doi: 10.1002/rth2.12004. eCollection 2017 Jul.

24.

Time trends in organ donation after neurologic determination of death: a cohort study.

Kramer AH, Baht R, Doig CJ.

CMAJ Open. 2017 Jan 13;5(1):E19-E27. doi: 10.9778/cmajo.20160093. eCollection 2017 Jan-Mar.

25.

11β-HSD1 Modulates the Set Point of Brown Adipose Tissue Response to Glucocorticoids in Male Mice.

Doig CL, Fletcher RS, Morgan SA, McCabe EL, Larner DP, Tomlinson JW, Stewart PM, Philp A, Lavery GG.

Endocrinology. 2017 Jun 1;158(6):1964-1976. doi: 10.1210/en.2016-1722.

26.

From Communication Skills to Skillful Communication: A Longitudinal Integrated Curriculum for Critical Care Medicine Fellows.

Roze des Ordons AL, Doig CJ, Couillard P, Lord J.

Acad Med. 2017 Apr;92(4):501-505. doi: 10.1097/ACM.0000000000001420.

PMID:
28351063
27.

Prevention of Hypoxemia During Apnea Testing: A Comparison of Oxygen Insufflation And Continuous Positive Airway Pressure.

Kramer AH, Couillard P, Bader R, Dhillon P, Kutsogiannis DJ, Doig CJ.

Neurocrit Care. 2017 Aug;27(1):60-67. doi: 10.1007/s12028-017-0380-0.

PMID:
28176180
28.

PARP Inhibitors: Staying on Target?

Doig CL, Lavery GG.

Cell Chem Biol. 2016 Dec 22;23(12):1442-1443. doi: 10.1016/j.chembiol.2016.12.003.

29.

Periorbital Myxedema.

Pham JT, Doig CT.

J Am Osteopath Assoc. 2016 Nov 1;116(11):753. doi: 10.7556/jaoa.2016.148. No abstract available.

PMID:
27802562
30.

11β-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation.

Hardy RS, Doig CL, Hussain Z, O'Leary M, Morgan SA, Pearson MJ, Naylor A, Jones SW, Filer A, Stewart PM, Buckley CD, Lavery GG, Cooper MS, Raza K.

J Pathol. 2016 Dec;240(4):472-483. doi: 10.1002/path.4806. Epub 2016 Oct 18.

31.

Assessment and predictors of physical functioning post-hospital discharge in survivors of critical illness.

Solverson KJ, Grant C, Doig CJ.

Ann Intensive Care. 2016 Dec;6(1):92. doi: 10.1186/s13613-016-0187-8. Epub 2016 Sep 20.

32.

Premortem Heparin Administration and Location of Withdrawal of Life-Sustaining Interventions in DCD: Lack of High-Quality Evidence Precludes Definitive Conclusions.

Kramer AH, Doig CJ.

Transplantation. 2016 Oct;100(10):e102-3. doi: 10.1097/TP.0000000000001378. No abstract available.

PMID:
27482963
33.

Male 11β-HSD1 Knockout Mice Fed Trans-Fats and Fructose Are Not Protected From Metabolic Syndrome or Nonalcoholic Fatty Liver Disease.

Larner DP, Morgan SA, Gathercole LL, Doig CL, Guest P, Weston C, Hazeldine J, Tomlinson JW, Stewart PM, Lavery GG.

Endocrinology. 2016 Sep;157(9):3493-504. doi: 10.1210/en.2016-1357. Epub 2016 Jul 6.

34.
35.

Assessment of sleep quality post-hospital discharge in survivors of critical illness.

Solverson KJ, Easton PA, Doig CJ.

Respir Med. 2016 May;114:97-102. doi: 10.1016/j.rmed.2016.03.009. Epub 2016 Mar 21.

36.

Glucocorticoids and 11β-HSD1 are major regulators of intramyocellular protein metabolism.

Morgan SA, Hassan-Smith ZK, Doig CL, Sherlock M, Stewart PM, Lavery GG.

J Endocrinol. 2016 Jun;229(3):277-86. doi: 10.1530/JOE-16-0011. Epub 2016 Apr 5.

37.
38.

Decompressive Craniectomy in Patients with Traumatic Brain Injury: Are the Usual Indications Congruent with Those Evaluated in Clinical Trials?

Kramer AH, Deis N, Ruddell S, Couillard P, Zygun DA, Doig CJ, Gallagher C.

Neurocrit Care. 2016 Aug;25(1):10-9. doi: 10.1007/s12028-015-0232-8.

PMID:
26732269
39.

Validation and optimisation of an ICD-10-coded case definition for sepsis using administrative health data.

Jolley RJ, Quan H, Jetté N, Sawka KJ, Diep L, Goliath J, Roberts DJ, Yipp BG, Doig CJ.

BMJ Open. 2015 Dec 23;5(12):e009487. doi: 10.1136/bmjopen-2015-009487.

40.

Engaging the Public to Identify Opportunities to Improve Critical Care: A Qualitative Analysis of an Open Community Forum.

Potestio ML, Boyd JM, Bagshaw SM, Heyland D, Oxland P, Doig CJ, Zygun D, Stelfox HT.

PLoS One. 2015 Nov 18;10(11):e0143088. doi: 10.1371/journal.pone.0143088. eCollection 2015.

41.

Working memory, reasoning, and expertise in medicine-insights into their relationship using functional neuroimaging.

Hruska P, Krigolson O, Coderre S, McLaughlin K, Cortese F, Doig C, Beran T, Wright B, Hecker KG.

Adv Health Sci Educ Theory Pract. 2016 Dec;21(5):935-952. doi: 10.1007/s10459-015-9649-2. Epub 2015 Nov 4. Erratum in: Adv Health Sci Educ Theory Pract. 2017 Oct;22(4):1049.

PMID:
26537964
42.

Hemispheric activation differences in novice and expert clinicians during clinical decision making.

Hruska P, Hecker KG, Coderre S, McLaughlin K, Cortese F, Doig C, Beran T, Wright B, Krigolson O.

Adv Health Sci Educ Theory Pract. 2016 Dec;21(5):921-933. doi: 10.1007/s10459-015-9648-3. Epub 2015 Nov 3. Erratum in: Adv Health Sci Educ Theory Pract. 2017 Oct;22(4):1047.

PMID:
26530736
43.

Stakeholder Engagement to Identify Priorities for Improving the Quality and Value of Critical Care.

Stelfox HT, Niven DJ, Clement FM, Bagshaw SM, Cook DJ, McKenzie E, Potestio ML, Doig CJ, O'Neill B, Zygun D; Critical Care Strategic Clinical Network, Alberta Health Services.

PLoS One. 2015 Oct 22;10(10):e0140141. doi: 10.1371/journal.pone.0140141. eCollection 2015.

44.

Assessing the association between occupancy and outcome in critically Ill hospitalized patients with sepsis.

Yergens DW, Ghali WA, Faris PD, Quan H, Jolley RJ, Doig CJ.

BMC Emerg Med. 2015 Oct 19;15:31. doi: 10.1186/s12873-015-0049-y.

45.

Knockdown of AKR1C3 exposes a potential epigenetic susceptibility in prostate cancer cells.

Doig CL, Battaglia S, Khanim FL, Bunce CM, Campbell MJ.

J Steroid Biochem Mol Biol. 2016 Jan;155(Pt A):47-55. doi: 10.1016/j.jsbmb.2015.09.037. Epub 2015 Sep 30.

46.

Integration of metabolic and inflammatory mediator profiles as a potential prognostic approach for septic shock in the intensive care unit.

Mickiewicz B, Tam P, Jenne CN, Leger C, Wong J, Winston BW, Doig C, Kubes P, Vogel HJ; Alberta Sepsis Network.

Crit Care. 2015 Jan 15;19:11. doi: 10.1186/s13054-014-0729-0.

47.

Validity of administrative data in recording sepsis: a systematic review.

Jolley RJ, Sawka KJ, Yergens DW, Quan H, Jetté N, Doig CJ.

Crit Care. 2015 Apr 6;19:139. doi: 10.1186/s13054-015-0847-3. Review.

48.

Active Negative Pressure Peritoneal Therapy After Abbreviated Laparotomy: The Intraperitoneal Vacuum Randomized Controlled Trial.

Kirkpatrick AW, Roberts DJ, Faris PD, Ball CG, Kubes P, Tiruta C, Xiao Z, Holodinsky JK, McBeth PB, Doig CJ, Jenne CN.

Ann Surg. 2015 Jul;262(1):38-46. doi: 10.1097/SLA.0000000000001095.

49.

Economic evaluation of the prophylaxis for thromboembolism in critical care trial (E-PROTECT): study protocol for a randomized controlled trial.

Fowler RA, Mittmann N, Geerts WH, Heels-Ansdell D, Gould MK, Guyatt G, Krahn M, Finfer S, Pinto R, Chan B, Ormanidhi O, Arabi Y, Qushmaq I, Rocha MG, Dodek P, McIntyre L, Hall R, Ferguson ND, Mehta S, Marshall JC, Doig CJ, Muscedere J, Jacka MJ, Klinger JR, Vlahakis N, Orford N, Seppelt I, Skrobik YK, Sud S, Cade JF, Cooper J, Cook D; Canadian Critical Care Trials Group; Australia and New Zealand Intensive Care Society Clinical Trials Group.

Trials. 2014 Dec 20;15:502. doi: 10.1186/1745-6215-15-502.

50.

Enhanced production of IGF-I in the lungs of fibroproliferative ARDS patients.

Andonegui G, Krein PM, Mowat C, Brisebois R, Doig C, Green FH, Léger C, Winston BW.

Physiol Rep. 2014 Nov 3;2(11). pii: e12197. doi: 10.14814/phy2.12197. Print 2014 Nov 1.

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