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Items: 1 to 50 of 1931

1.

How to prevent adverse events of vascular stapling in thoracic surgery: recommendations based on a clinical and experimental study.

Shimizu N, Tanaka Y, Okamoto T, Doi T, Hokka D, Maniwa Y.

J Thorac Dis. 2018 Dec;10(12):6466-6471. doi: 10.21037/jtd.2018.11.14.

2.

Cell-autonomous and redundant roles of Hey1 and HeyL in muscle stem cells: HeyL requires Hes1 to bind diverse DNA sites.

Noguchi YT, Nakamura M, Hino N, Nogami J, Tsuji S, Sato T, Zhang L, Tsujikawa K, Tanaka T, Izawa K, Okada Y, Doi T, Kokubo H, Harada A, Uezumi A, Gessler M, Ohkawa Y, Fukada SI.

Development. 2019 Feb 11. pii: dev.163618. doi: 10.1242/dev.163618. [Epub ahead of print]

PMID:
30745427
3.

KEYNOTE-590: Phase III study of first-line chemotherapy with or without pembrolizumab for advanced esophageal cancer.

Kato K, Shah MA, Enzinger P, Bennouna J, Shen L, Adenis A, Sun JM, Cho BC, Özgüroğlu M, Kojima T, Kostorov V, Hierro C, Zhu Y, McLean LA, Shah S, Doi T.

Future Oncol. 2019 Feb 8. doi: 10.2217/fon-2018-0609. [Epub ahead of print]

4.

Phase I Study of the Focal Adhesion Kinase Inhibitor BI 853520 in Japanese and Taiwanese Patients with Advanced or Metastatic Solid Tumors.

Doi T, Yang JC, Shitara K, Naito Y, Cheng AL, Sarashina A, Pronk LC, Takeuchi Y, Lin CC.

Target Oncol. 2019 Feb 6. doi: 10.1007/s11523-019-00620-0. [Epub ahead of print]

PMID:
30725402
5.

Phase I dose-escalation study of capmatinib (INC280) in Japanese patients with advanced solid tumors.

Esaki T, Hirai F, Makiyama A, Seto T, Bando H, Naito Y, Yoh K, Ishihara K, Kakizume T, Natsume K, Myers A, Doi T.

Cancer Sci. 2019 Feb 6. doi: 10.1111/cas.13956. [Epub ahead of print]

6.

Direct oral anticoagulant successfully used to treat an adult nephrotic patient complicated with portal vein thrombosis.

Obata F, Abe H, Murakami T, Ueda S, Inagaki T, Minato M, Ono H, Nishimura K, Shibata E, Tamaki M, Kishi F, Kishi S, Nagai K, Doi T.

CEN Case Rep. 2019 Feb 5. doi: 10.1007/s13730-019-00381-9. [Epub ahead of print]

7.

Emulsion-based control of flavor release profiles: Impact of oil droplet characteristics on garlic aroma release during simulated cooking.

Doi T, Wang M, McClements DJ.

Food Res Int. 2019 Feb;116:1-11. doi: 10.1016/j.foodres.2018.12.056. Epub 2018 Dec 25.

PMID:
30716881
8.

Clinicopathological and molecular features of responders to nivolumab for patients with advanced gastric cancer.

Mishima S, Kawazoe A, Nakamura Y, Sasaki A, Kotani D, Kuboki Y, Bando H, Kojima T, Doi T, Ohtsu A, Yoshino T, Kuwata T, Tsuji A, Shitara K.

J Immunother Cancer. 2019 Jan 31;7(1):24. doi: 10.1186/s40425-019-0514-3.

9.

First-in-human phase I study of an oral HSP90 inhibitor, TAS-116, in patients with advanced solid tumors.

Shimomura A, Yamamoto N, Kondo S, Fujiwara Y, Suzuki S, Yanagitani N, Horiike A, Kitazono S, Ohyanagi F, Doi T, Kuboki Y, Kawazoe A, Shitara K, Ohno I, Banerji U, Sundar R, Ohkubo S, Calleja EM, Nishio M.

Mol Cancer Ther. 2019 Jan 24. pii: molcanther.0831.2018. doi: 10.1158/1535-7163.MCT-18-0831. [Epub ahead of print]

PMID:
30679388
10.

ROS1-rearranged high-PD-L1-expressing lung adenocarcinoma manifesting as mediastinal tumor: A case report.

Ogawa H, Tanaka Y, Tachihara M, Uehara K, Shimizu N, Doi T, Hokka D, Maniwa Y.

Oncol Lett. 2019 Jan;17(1):488-491. doi: 10.3892/ol.2018.9622. Epub 2018 Oct 25.

11.

Lipin-1 is a novel substrate of protein phosphatase PGAM5.

Okuno H, Okuzono H, Hayase A, Kumagai F, Tanii S, Hino N, Okada Y, Tachibana K, Doi T, Ishimoto K.

Biochem Biophys Res Commun. 2019 Feb 19;509(4):886-891. doi: 10.1016/j.bbrc.2019.01.031. Epub 2019 Jan 11.

PMID:
30642635
12.

Predictive factors for hyperprogressive disease during nivolumab as anti-PD1 treatment in patients with advanced gastric cancer.

Sasaki A, Nakamura Y, Mishima S, Kawazoe A, Kuboki Y, Bando H, Kojima T, Doi T, Ohtsu A, Yoshino T, Kuwata T, Akimoto T, Shitara K.

Gastric Cancer. 2019 Jan 9. doi: 10.1007/s10120-018-00922-8. [Epub ahead of print]

PMID:
30627987
13.

A phase I study of ontuxizumab, a humanized monoclonal antibody targeting endosialin, in Japanese patients with solid tumors.

Doi T, Aramaki T, Yasui H, Muro K, Ikeda M, Okusaka T, Inaba Y, Nakai K, Ikezawa H, Nakajima R.

Invest New Drugs. 2019 Jan 9. doi: 10.1007/s10637-018-0713-7. [Epub ahead of print]

PMID:
30623276
14.

All-trans retinoic acid suppresses bone morphogenetic protein 4 in mouse diabetic nephropathy through a unique retinoic acid response element.

Tamaki M, Tominaga T, Fujita Y, Koezuka Y, Ichien G, Murakami T, Kishi S, Yamamoto K, Abe H, Nagai K, Doi T.

Am J Physiol Endocrinol Metab. 2019 Jan 2. doi: 10.1152/ajpendo.00218.2018. [Epub ahead of print]

PMID:
30601699
15.

[Impact of Primary Prophylaxis with Pegfilgrastim on Clinical Outcomes in Patients with Advanced Esophageal Cancer Receiving Chemotherapy with Docetaxel, Cisplatin ,and 5-FU].

Yasuda T, Ishikawa T, Ohta T, Yoshida J, Doi T, Dohi O, Okayama T, Yoshida N, Kamada K, Uchiyama K, Handa O, Takagi T, Konishi H, Shiozaki A, Fujiwara H, Naito Y, Itoh Y.

Gan To Kagaku Ryoho. 2018 Dec;45(12):1733-1736. Japanese.

PMID:
30587730
16.

Scrotal/testicular status after repair of recent severe incarcerated inguinal hernia in male infants younger than 12 months old: Laparoscopic percutaneous extraperitoneal closure versus conventional open repair.

Miyano G, Nakamura H, Shibuya S, Ochi T, Yazaki Y, Murakami H, Seo S, Okawada M, Doi T, Koga H, Lane GJ, Yamataka A.

Asian J Endosc Surg. 2018 Dec 19. doi: 10.1111/ases.12680. [Epub ahead of print]

PMID:
30569579
17.

Associations of Skeletal Muscle Mass, Lower-Extremity Functioning, and Cognitive Impairment in Community-Dwelling Older People in Japan.

Ishii H, Makizako H, Doi T, Tsutsumimoto K, Shimada H.

J Nutr Health Aging. 2019;23(1):35-41. doi: 10.1007/s12603-018-1110-9.

PMID:
30569066
18.

T-Cell-Inflamed Gene-Expression Profile, Programmed Death Ligand 1 Expression, and Tumor Mutational Burden Predict Efficacy in Patients Treated With Pembrolizumab Across 20 Cancers: KEYNOTE-028.

Ott PA, Bang YJ, Piha-Paul SA, Razak ARA, Bennouna J, Soria JC, Rugo HS, Cohen RB, O'Neil BH, Mehnert JM, Lopez J, Doi T, van Brummelen EMJ, Cristescu R, Yang P, Emancipator K, Stein K, Ayers M, Joe AK, Lunceford JK.

J Clin Oncol. 2019 Feb 1;37(4):318-327. doi: 10.1200/JCO.2018.78.2276. Epub 2018 Dec 13.

PMID:
30557521
19.

Factors affecting non-operative management of uncomplicated appendicitis in children: Should laparoscopic appendectomy be immediate, interval, or emergency?

Miyano G, Ochi T, Seo S, Nakamura H, Okawada M, Doi T, Koga H, Lane GJ, Yamataka A.

Asian J Endosc Surg. 2018 Dec 11. doi: 10.1111/ases.12677. [Epub ahead of print]

PMID:
30548102
20.

Myo-inositol oxygenase accentuates renal tubular injury initiated by endoplasmic reticulum stress.

Tominaga T, Sharma I, Fujita Y, Doi T, Wallner AK, Kanwar YS.

Am J Physiol Renal Physiol. 2019 Feb 1;316(2):F301-F315. doi: 10.1152/ajprenal.00534.2018. Epub 2018 Dec 12.

PMID:
30539651
21.

Sleep condition and cognitive decline in Japanese community-dwelling older people: Data from a 4-year longitudinal study.

Nakakubo S, Doi T, Makizako H, Tsutsumimoto K, Hotta R, Kurita S, Kim M, Suzuki T, Shimada H.

J Sleep Res. 2018 Dec 9:e12803. doi: 10.1111/jsr.12803. [Epub ahead of print]

PMID:
30537088
22.

Anti-Claudin Antibodies as a Concept for Development of Claudin-Directed Drugs.

Hashimoto Y, Okada Y, Shirakura K, Tachibana K, Sawada M, Yagi K, Doi T, Kondoh M.

J Pharmacol Exp Ther. 2019 Feb;368(2):179-186. doi: 10.1124/jpet.118.252361. Epub 2018 Dec 7.

PMID:
30530622
23.

Brain-Specific Ultrastructure of Capillary Endothelial Glycocalyx and Its Possible Contribution for Blood Brain Barrier.

Ando Y, Okada H, Takemura G, Suzuki K, Takada C, Tomita H, Zaikokuji R, Hotta Y, Miyazaki N, Yano H, Muraki I, Kuroda A, Fukuda H, Kawasaki Y, Okamoto H, Kawaguchi T, Watanabe T, Doi T, Yoshida T, Ushikoshi H, Yoshida S, Ogura S.

Sci Rep. 2018 Nov 30;8(1):17523. doi: 10.1038/s41598-018-35976-2.

24.

Phase 1 trial of avelumab (anti-PD-L1) in Japanese patients with advanced solid tumors, including dose expansion in patients with gastric or gastroesophageal junction cancer: the JAVELIN Solid Tumor JPN trial.

Doi T, Iwasa S, Muro K, Satoh T, Hironaka S, Esaki T, Nishina T, Hara H, Machida N, Komatsu Y, Shimada Y, Otsu S, Shimizu S, Watanabe M.

Gastric Cancer. 2018 Dec 4. doi: 10.1007/s10120-018-0903-1. [Epub ahead of print]

PMID:
30515672
25.

First-in-human phase 1 study of novel dUTPase inhibitor TAS-114 in combination with S-1 in Japanese patients with advanced solid tumors.

Doi T, Yoh K, Shitara K, Takahashi H, Ueno M, Kobayashi S, Morimoto M, Okusaka T, Ueno H, Morizane C, Okano N, Nagashima F, Furuse J.

Invest New Drugs. 2018 Dec 4. doi: 10.1007/s10637-018-0697-3. [Epub ahead of print]

PMID:
30511200
26.

The Robo4-TRAF7 complex suppresses endothelial hyperpermeability in inflammation.

Shirakura K, Ishiba R, Kashio T, Funatsu R, Tanaka T, Fukada SI, Ishimoto K, Hino N, Kondoh M, Ago Y, Fujio Y, Yano K, Doi T, Aird WC, Okada Y.

J Cell Sci. 2019 Jan 2;132(1). pii: jcs220228. doi: 10.1242/jcs.220228.

PMID:
30510113
27.

Cognitive Frailty is Associated with Fall-Related Fracture among Older People.

Tsutsumimoto K, Doi T, Makizako H, Hotta R, Nakakubo S, Makino K, Suzuki T, Shimada H.

J Nutr Health Aging. 2018;22(10):1216-1220. doi: 10.1007/s12603-018-1131-4.

PMID:
30498829
28.

Synthesis and biological evaluation of thielocin B1 analogues as protein-protein interaction inhibitors of PAC3 homodimer.

Ohsawa K, Yoshida M, Izumikawa M, Takagi M, Shin-Ya K, Goshima N, Hirokawa T, Natsume T, Doi T.

Bioorg Med Chem. 2018 Dec 15;26(23-24):6023-6034. doi: 10.1016/j.bmc.2018.11.001. Epub 2018 Nov 7.

PMID:
30455074
29.

[Successful Treatment of a Patient with Idiopathic Subglottic Stenosis].

Shimizu N, Tanaka Y, Kuroda S, Nakamura H, Matsumoto G, Mitsui S, Sakai S, Minami K, Okamoto T, Doi T, Hokka D, Maniwa Y.

Kyobu Geka. 2018 Nov;71(12):1018-1021. Japanese.

PMID:
30449870
30.

A Case of Systemic Sarcoidosis Presenting with Renal Involvement Caused by Various Sarcoidosis-associated Pathophysiological Conditions.

Ueda S, Murakami T, Ogino H, Matsuura M, Tamaki M, Kishi S, Hann M, Toyoda Y, Nagai K, Bando Y, Abe H, Nishioka Y, Doi T.

Intern Med. 2018 Nov 19. doi: 10.2169/internalmedicine.1558-18. [Epub ahead of print]

31.

Efficacy and safety of ramucirumab-containing chemotherapy in patients with pretreated metastatic gastric neuroendocrine carcinoma.

Mishima S, Kawazoe A, Matsumoto H, Kuboki Y, Bando H, Kojima T, Doi T, Ohtsu A, Yoshino T, Nonte EM, Chintharlapalli S, Nasir A, Kuwata T, Shitara K.

ESMO Open. 2018 Nov 1;3(7):e000443. doi: 10.1136/esmoopen-2018-000443. eCollection 2018.

32.

Long and Short Sleep Duration and Physical Frailty in Community-Dwelling Older Adults.

Nakakubo S, Makizako H, Doi T, Tsutsumimoto K, Hotta R, Lee S, Lee S, Bae S, Makino K, Suzuki T, Shimada H.

J Nutr Health Aging. 2018;22(9):1066-1071. doi: 10.1007/s12603-018-1116-3.

PMID:
30379304
33.

Determination of the Anisotropic Rotational Diffusion Constant of Microcrystals Dispersed in Liquid Medium.

Kimura F, Horii S, Arimoto I, Doi T, Yoshimura M, Wada M, Kimura T.

J Phys Chem A. 2018 Nov 21;122(46):9123-9127. doi: 10.1021/acs.jpca.8b08895. Epub 2018 Nov 9.

PMID:
30375868
34.

Transforming growth factor β1-induced collagen production in myofibroblasts is mediated by reactive oxygen species derived from NADPH oxidase 4.

Hotta Y, Uchiyama K, Takagi T, Kashiwagi S, Nakano T, Mukai R, Toyokawa Y, Yasuda T, Ueda T, Suyama Y, Murakami T, Tanaka M, Majima A, Doi T, Hirai Y, Mizushima K, Morita M, Higashimura Y, Inoue K, Fukui A, Okayama T, Katada K, Kamada K, Handa O, Ishikawa T, Naito Y, Itoh Y.

Biochem Biophys Res Commun. 2018 Nov 30;506(3):557-562. doi: 10.1016/j.bbrc.2018.10.116. Epub 2018 Oct 23.

PMID:
30361098
35.

Trifluridine/tipiracil versus placebo in patients with heavily pretreated metastatic gastric cancer (TAGS): a randomised, double-blind, placebo-controlled, phase 3 trial.

Shitara K, Doi T, Dvorkin M, Mansoor W, Arkenau HT, Prokharau A, Alsina M, Ghidini M, Faustino C, Gorbunova V, Zhavrid E, Nishikawa K, Hosokawa A, Yalçın Ş, Fujitani K, Beretta GD, Cutsem EV, Winkler RE, Makris L, Ilson DH, Tabernero J.

Lancet Oncol. 2018 Nov;19(11):1437-1448. doi: 10.1016/S1470-2045(18)30739-3. Epub 2018 Oct 21. Erratum in: Lancet Oncol. 2018 Dec;19(12):e668.

PMID:
30355453
36.

Targeting VEGFR2 with Ramucirumab strongly impacts effector/ activated regulatory T cells and CD8+ T cells in the tumor microenvironment.

Tada Y, Togashi Y, Kotani D, Kuwata T, Sato E, Kawazoe A, Doi T, Wada H, Nishikawa H, Shitara K.

J Immunother Cancer. 2018 Oct 11;6(1):106. doi: 10.1186/s40425-018-0403-1.

37.

[Continuous Chest Drainage Systems in Thoracic Surgery].

Doi T, Maniwa Y.

Kyobu Geka. 2018 Sep;71(10):881-885. Japanese.

PMID:
30310043
38.

Impact of dapagliflozin on left ventricular diastolic function of patients with type 2 diabetic mellitus with chronic heart failure.

Soga F, Tanaka H, Tatsumi K, Mochizuki Y, Sano H, Toki H, Matsumoto K, Shite J, Takaoka H, Doi T, Hirata KI.

Cardiovasc Diabetol. 2018 Oct 8;17(1):132. doi: 10.1186/s12933-018-0775-z.

39.

Urinary Exosomal mRNA of WT1 as Diagnostic and Prognostic Biomarker for Diabetic Nephropathy.

Abe H, Sakurai A, Ono H, Hayashi S, Yoshimoto S, Ochi A, Ueda S, Nishimura K, Shibata E, Tamaki M, Kishi F, Kishi S, Murakami T, Nagai K, Doi T.

J Med Invest. 2018;65(3.4):208-215. doi: 10.2152/jmi.65.208.

40.

Cognitive activity in a sitting position is protectively associated with cognitive impairment among older adults.

Kurita S, Doi T, Tsutsumimoto K, Hotta R, Nakakubo S, Kim M, Shimada H.

Geriatr Gerontol Int. 2019 Feb;19(2):98-102. doi: 10.1111/ggi.13532. Epub 2018 Oct 2.

PMID:
30276939
41.

Effect of high-flow high-volume-intermittent hemodiafiltration on metformin-associated lactic acidosis with circulatory failure: a case report.

Suzuki K, Okada H, Yoshida S, Okamoto H, Suzuki A, Suzuki K, Yamada Y, Hayashi H, Yasuda R, Fukuta T, Kitagawa Y, Miyake T, Kawaguchi T, Watanabe T, Doi T, Kumada K, Ushikoshi H, Sugiyama T, Itoh Y, Ogura S.

J Med Case Rep. 2018 Sep 29;12(1):280. doi: 10.1186/s13256-018-1809-6.

42.

Transitional status and modifiable risk of frailty in Japanese older adults: A prospective cohort study.

Doi T, Makizako H, Tsutsumimoto K, Nakakubo S, Kim MJ, Kurita S, Hotta R, Shimada H.

Geriatr Gerontol Int. 2018 Nov;18(11):1562-1566. doi: 10.1111/ggi.13525. Epub 2018 Sep 17.

PMID:
30225955
43.

The associations between physical activity, including physical activity intensity, and fear of falling differs by fear severity in older adults living in the community.

Sawa R, Asai T, Doi T, Misu S, Murata S, Ono R.

J Gerontol B Psychol Sci Soc Sci. 2018 Sep 14. doi: 10.1093/geronb/gby103. [Epub ahead of print]

PMID:
30219902
44.

Rac Regulates the TRAP-Induced Release of Phosphorylated-HSP27 from Human Platelets via p38 MAP Kinase but Not JNK.

Uematsu K, Enomoto Y, Onuma T, Tsujimoto M, Doi T, Matsushima-Nishiwaki R, Tokuda H, Ogura S, Iida H, Kozawa O, Iwama T.

Cell Physiol Biochem. 2018;49(4):1523-1538. doi: 10.1159/000493456. Epub 2018 Sep 13.

45.

Cognitive Frailty Predicts Incident Dementia among Community-Dwelling Older People.

Shimada H, Doi T, Lee S, Makizako H, Chen LK, Arai H.

J Clin Med. 2018 Aug 30;7(9). pii: E250. doi: 10.3390/jcm7090250.

46.

Association of walk ratio during normal gait speed and fall in community-dwelling elderly people.

Nakakubo S, Doi T, Makizako H, Tsutsumimoto K, Hotta R, Kurita S, Kim M, Suzuki T, Shimada H.

Gait Posture. 2018 Oct;66:151-154. doi: 10.1016/j.gaitpost.2018.08.030. Epub 2018 Aug 25.

PMID:
30195217
48.

[Solitary Pulmonary Metastasis from Carcinoma of the Ampulla of Vater after Pancreatoduodenectomy;Report of a Case].

Doi T, Sakamoto T, Okino T.

Kyobu Geka. 2018 Sep;71(9):708-711. Japanese.

PMID:
30185749
49.

An adjustment in BMP4 function represents a treatment for diabetic nephropathy and podocyte injury.

Fujita Y, Tominaga T, Abe H, Kangawa Y, Fukushima N, Ueda O, Jishage KI, Kishi S, Murakami T, Saga Y, Kanwar YS, Nagai K, Doi T.

Sci Rep. 2018 Aug 29;8(1):13011. doi: 10.1038/s41598-018-31464-9.

50.

Development of a detection method for antisense oligonucleotides in mouse kidneys by matrix-assisted laser desorption/ionization imaging mass spectrometry.

Yokoi H, Kasahara Y, Obika S, Doi T, Kamada H.

Rapid Commun Mass Spectrom. 2018 Dec 15;32(23):1984-1990. doi: 10.1002/rcm.8274.

PMID:
30152908

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