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Phase II trial of ponatinib in patients with bevacizumab-refractory glioblastoma.

Lee EQ, Muzikansky A, Duda DG, Gaffey S, Dietrich J, Nayak L, Chukwueke UN, Beroukhim R, Doherty L, Laub CK, LaFrankie D, Fontana B, Stefanik J, Ruland S, Caruso V, Bruno J, Ligon K, Reardon DA, Wen PY.

Cancer Med. 2019 Oct;8(13):5988-5994. doi: 10.1002/cam4.2505. Epub 2019 Aug 24.


Risk behaviours of homeless people who inject drugs during an outbreak of hepatitis C, Northern Ireland, 2016-2017.

Maisa A, Semple S, Griffiths A, Ngui SL, Verlander NQ, McCaughey C, Doherty L, Jessop L; Outbreak Control Team.

J Viral Hepat. 2019 Jul 22. doi: 10.1111/jvh.13184. [Epub ahead of print]


E-cigarettes and smoking cessation: a prospective study of a national sample of pregnant smokers.

Chiang SC, Abroms LC, Cleary SD, Pant I, Doherty L, Krishnan N.

BMC Public Health. 2019 Jul 18;19(1):964. doi: 10.1186/s12889-019-7299-7.


Acute stressor alters inter-species microbial competition for resistant starch-supplemented medium.

Pantoja-Feliciano IG, Soares JW, Doherty LA, Karl JP, McClung HL, Armstrong NJ, Branck TA, Arcidiacono S.

Gut Microbes. 2019;10(4):439-446. doi: 10.1080/19490976.2018.1554962. Epub 2018 Dec 22.


Cbl-PI3K interaction regulates Cathepsin K secretion in osteoclasts.

Yu J, Adapala NS, Doherty L, Sanjay A.

Bone. 2019 Oct;127:376-385. doi: 10.1016/j.bone.2019.07.009. Epub 2019 Jul 9.


Stopping oral steroid-sparing agents at initiation of rituximab in myasthenia gravis.

Roda RH, Doherty L, Corse AM.

Neuromuscul Disord. 2019 Jul;29(7):554-561. doi: 10.1016/j.nmd.2019.06.002. Epub 2019 Jun 6.


Barriers to Accrual and Enrollment in Brain Tumor Trials.

Lee EQ, Chukwueke UN, Hervey-Jumper SL, de Groot JF, Leone JP, Armstrong TS, Chang SM, Arons D, Oliver K, Verble K, Musella A, Willmarth N, Alexander BM, Bates A, Doherty L, Galanis E, Gaffey S, Halkin T, Friday BE, Fouladi M, Lin NU, Macdonald D, Mehta MP, Penas-Prado M, Vogelbaum MA, Sahebjam S, Sandak D, van den Bent M, Weller M, Reardon DA, Wen PY.

Neuro Oncol. 2019 Jun 7. pii: noz104. doi: 10.1093/neuonc/noz104. [Epub ahead of print]


Zintl Phases as Reactive Precursors for Synthesis of Novel Silicon and Germanium-Based Materials.

Beekman M, Kauzlarich SM, Doherty L, Nolas GS.

Materials (Basel). 2019 Apr 8;12(7). pii: E1139. doi: 10.3390/ma12071139. Review.


Engineering NaV1.7 Inhibitory JzTx-V Peptides with a Potency and Basicity Profile Suitable for Antibody Conjugation To Enhance Pharmacokinetics.

Murray JK, Wu B, Tegley CM, Nixey TE, Falsey JR, Herberich B, Yin L, Sham K, Long J, Aral J, Cheng Y, Netirojjanakul C, Doherty L, Glaus C, Ikotun T, Li H, Tran L, Soto M, Salimi-Moosavi H, Ligutti J, Amagasu S, Andrews KL, Be X, Lin MJ, Foti RS, Ilch CP, Youngblood B, Kornecook TJ, Karow M, Walker KW, Moyer BD, Biswas K, Miranda LP.

ACS Chem Biol. 2019 Apr 19;14(4):806-818. doi: 10.1021/acschembio.9b00183. Epub 2019 Mar 27.


Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion.

Harris IS, Endress JE, Coloff JL, Selfors LM, McBrayer SK, Rosenbluth JM, Takahashi N, Dhakal S, Koduri V, Oser MG, Schauer NJ, Doherty LM, Hong AL, Kang YP, Younger ST, Doench JG, Hahn WC, Buhrlage SJ, DeNicola GM, Kaelin WG Jr, Brugge JS.

Cell Metab. 2019 May 7;29(5):1166-1181.e6. doi: 10.1016/j.cmet.2019.01.020. Epub 2019 Feb 21.


Discovery of a First-In-Class Covalent Allosteric Inhibitor of SUMO E1 Activating Enzyme.

Magin RS, Doherty LM, Buhrlage SJ.

Cell Chem Biol. 2019 Feb 21;26(2):153-155. doi: 10.1016/j.chembiol.2019.02.006.


Group B streptococcal disease in UK and Irish infants younger than 90 days, 2014-15: a prospective surveillance study.

O'Sullivan CP, Lamagni T, Patel D, Efstratiou A, Cunney R, Meehan M, Ladhani S, Reynolds AJ, Campbell R, Doherty L, Boyle M, Kapatai G, Chalker V, Lindsay D, Smith A, Davies E, Jones CE, Heath PT.

Lancet Infect Dis. 2019 Jan;19(1):83-90. doi: 10.1016/S1473-3099(18)30555-3. Epub 2018 Nov 26.


Approved Treatments for Patients with Recurrent High-grade Gliomas.

Laub CK, Stefanik J, Doherty L.

Semin Oncol Nurs. 2018 Dec;34(5):486-493. doi: 10.1016/j.soncn.2018.10.005. Epub 2018 Nov 2. Review.


Effects of Psychological, Environmental and Physical Stressors on the Gut Microbiota.

Karl JP, Hatch AM, Arcidiacono SM, Pearce SC, Pantoja-Feliciano IG, Doherty LA, Soares JW.

Front Microbiol. 2018 Sep 11;9:2013. doi: 10.3389/fmicb.2018.02013. eCollection 2018. Review.


Inadequate Communication Exacerbates the Support Needs of Current and Bereaved Caregivers in Advanced Heart Failure and Impedes Shared Decision-making.

Fitzsimons D, Doherty LC, Murphy M, Dixon L, Donnelly P, McDonald K, McIlfatrick S.

J Cardiovasc Nurs. 2019 Jan/Feb;34(1):11-19. doi: 10.1097/JCN.0000000000000516.


A Case-control Study to Evaluate the Prevalence of Nonalcoholic Fatty Liver Disease Among Patients with Moderate-to-severe Psoriasis.

Awosika O, Eleryan MG, Rengifo-Pardo M, Doherty L, Martin LW, Ehrlich A.

J Clin Aesthet Dermatol. 2018 Jun;11(6):33-37. Epub 2018 Jun 1.


Phase I and Biomarker Study of Plerixafor and Bevacizumab in Recurrent High-Grade Glioma.

Lee EQ, Duda DG, Muzikansky A, Gerstner ER, Kuhn JG, Reardon DA, Nayak L, Norden AD, Doherty L, LaFrankie D, Stefanik J, Vardam T, Smith KH, McCluskey C, Gaffey S, Batchelor TT, Jain RK, Wen PY.

Clin Cancer Res. 2018 Oct 1;24(19):4643-4649. doi: 10.1158/1078-0432.CCR-18-1025. Epub 2018 Jun 25.


Inflammatory response following in vitro exposure to methylmercury with and without n-3 long chain polyunsaturated fatty acids in peripheral blood mononuclear cells from systemic lupus erythematosus patients compared to healthy controls.

Crowe W, Allsopp PJ, Nyland JF, Magee PJ, Strain JJ, Doherty LC, Watson GE, Ball E, Riddell C, Armstrong DJ, Penta K, Todd JJ, Spence T, McSorley EM.

Toxicol In Vitro. 2018 Oct;52:272-278. doi: 10.1016/j.tiv.2018.05.008. Epub 2018 May 17.


Extent of Playing-Related Musculoskeletal Problems in the Irish Traditional Music Community: A Survey.

Porter M, Wilson IM, Doherty L, Magee J.

Med Probl Perform Art. 2018 Mar;33(1):47-55. doi: 10.21091/mppa.2018.1008.


Time for a new resistance against antibiotics.

Bradley D, Doherty L.

Ulster Med J. 2017 Sep;86(3):157-158. Epub 2017 Sep 12. No abstract available.


'The importance of planning for the future': Burden and unmet needs of caregivers' in advanced heart failure: A mixed methods study.

McIlfatrick S, Doherty LC, Murphy M, Dixon L, Donnelly P, McDonald K, Fitzsimons D.

Palliat Med. 2018 Apr;32(4):881-890. doi: 10.1177/0269216317743958. Epub 2017 Dec 13.


Adverse Maternal and Neonatal Outcomes in Indicated Compared with Spontaneous Preterm Birth in Healthy Nulliparas: A Secondary Analysis of a Randomized Trial.

Tita AT, Doherty L, Roberts JM, Myatt L, Leveno KJ, Varner MW, Wapner RJ, Thorp JM Jr, Mercer BM, Peaceman A, Ramin SM, Carpenter MW, Iams J, Sciscione A, Harper M, Tolosa JE, Saade GR, Sorokin Y; Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.

Am J Perinatol. 2018 Jun;35(7):624-631. doi: 10.1055/s-0037-1608787. Epub 2017 Nov 30.


Influence of glass wool as separator on bioelectricity generation in a constructed wetland-microbial fuel cell.

Xu L, Zhao Y, Tang C, Doherty L.

J Environ Manage. 2018 Feb 1;207:116-123. doi: 10.1016/j.jenvman.2017.11.035. Epub 2017 Nov 16.


Inhibition of USP10 induces degradation of oncogenic FLT3.

Weisberg EL, Schauer NJ, Yang J, Lamberto I, Doherty L, Bhatt S, Nonami A, Meng C, Letai A, Wright R, Tiv H, Gokhale PC, Ritorto MS, De Cesare V, Trost M, Christodoulou A, Christie A, Weinstock DM, Adamia S, Stone R, Chauhan D, Anderson KC, Seo HS, Dhe-Paganon S, Sattler M, Gray NS, Griffin JD, Buhrlage SJ.

Nat Chem Biol. 2017 Dec;13(12):1207-1215. doi: 10.1038/nchembio.2486. Epub 2017 Oct 2.


Engineering Antibody Reactivity for Efficient Derivatization to Generate NaV1.7 Inhibitory GpTx-1 Peptide-Antibody Conjugates.

Biswas K, Nixey TE, Murray JK, Falsey JR, Yin L, Liu H, Gingras J, Hall BE, Herberich B, Holder JR, Li H, Ligutti J, Lin MJ, Liu D, Soriano BD, Soto M, Tran L, Tegley CM, Zou A, Gunasekaran K, Moyer BD, Doherty L, Miranda LP.

ACS Chem Biol. 2017 Sep 15;12(9):2427-2435. doi: 10.1021/acschembio.7b00542. Epub 2017 Aug 28.


Constructed wetland integrated microbial fuel cell system: looking back, moving forward.

Wang Y, Zhao Y, Xu L, Wang W, Doherty L, Tang C, Ren B, Zhao J.

Water Sci Technol. 2017 Jul;76(2):471-477. doi: 10.2166/wst.2017.190.


Serious pneumococcal disease outbreak in men exposed to metal fume - detection, response and future prevention through pneumococcal vaccination.

Ewing J, Patterson L, Irvine N, Doherty L, Loughrey A, Kidney J, Sheppard C, Kapatai G, Fry NK, Ramsay M, Jessop L.

Vaccine. 2017 Jul 13;35(32):3945-3950. doi: 10.1016/j.vaccine.2017.06.010. Epub 2017 Jun 19.


Anti-DPPX encephalitis: prominent nystagmus reflected by extraocular muscle FDG-PET avidity.

Doherty L, Gold D, Solnes L, Probasco J, Venkatesan A.

Neurol Neuroimmunol Neuroinflamm. 2017 Jun 5;4(4):e361. doi: 10.1212/NXI.0000000000000361. eCollection 2017 Jul. No abstract available.


Insidious Risk of Severe Mycobacterium chimaera Infection in Cardiac Surgery Patients.

Chand M, Lamagni T, Kranzer K, Hedge J, Moore G, Parks S, Collins S, Del Ojo Elias C, Ahmed N, Brown T, Smith EG, Hoffman P, Kirwan P, Mason B, Smith-Palmer A, Veal P, Lalor MK, Bennett A, Walker J, Yeap A, Isidro Carrion Martin A, Dolan G, Bhatt S, Skingsley A, Charlett A, Pearce D, Russell K, Kendall S, Klein AA, Robins S, Schelenz S, Newsholme W, Thomas S, Collyns T, Davies E, McMenamin J, Doherty L, Peto TE, Crook D, Zambon M, Phin N.

Clin Infect Dis. 2017 Feb 1;64(3):335-342. doi: 10.1093/cid/ciw754. Epub 2016 Dec 7. Erratum in: Clin Infect Dis. 2017 Sep 1;65(5):875.


The Positive Impact of Bariatric Surgery on Sleep.

Xie H, Doherty L, O'Boyle C.

Ir Med J. 2016 Jan;109(1):328-30.


A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy.

Lee EQ, Muzikansky A, Drappatz J, Kesari S, Wong ET, Fadul CE, Reardon DA, Norden AD, Nayak L, Rinne ML, Alexander BM, Arvold ND, Doherty L, Stefanik J, LaFrankie D, Ruland SF, Pulverenti J, Smith KH, Gaffey SC, Hammond S, Wen PY.

Neuro Oncol. 2016 Jun;18(6):849-54. doi: 10.1093/neuonc/now007. Epub 2016 Feb 21.


Fish viruses make dsRNA in fish cells: characterization of dsRNA production in rainbow trout (Oncorhynchus mykiss) cells infected with viral haemorrhagic septicaemia virus, chum salmon reovirus and frog virus 3.

Doherty L, Poynter SJ, Aloufi A, DeWitte-Orr SJ.

J Fish Dis. 2016 Sep;39(9):1133-7. doi: 10.1111/jfd.12443. Epub 2016 Jan 18. No abstract available.


Mercury in Hair Is Inversely Related to Disease Associated Damage in Systemic Lupus Erythematosus.

Crowe W, Doherty L, Watson G, Armstrong D, Ball E, Magee P, Allsopp P, Bell A, Strain JJ, McSorley E.

Int J Environ Res Public Health. 2015 Dec 23;13(1):ijerph13010075. doi: 10.3390/ijerph13010075.


Low public health risk of MERS-CoV in people returning from the Hajj.

Waldron G, Doherty L.

BMJ. 2015 Oct 21;351:h5543. doi: 10.1136/bmj.h5543. No abstract available.


A review of a recently emerged technology: Constructed wetland--Microbial fuel cells.

Doherty L, Zhao Y, Zhao X, Hu Y, Hao X, Xu L, Liu R.

Water Res. 2015 Nov 15;85:38-45. doi: 10.1016/j.watres.2015.08.016. Epub 2015 Aug 12. Review.


Outbreak of invasive pneumococcal disease at a Belfast shipyard in men exposed to welding fumes, Northern Ireland, April-May 2015: preliminary report.

Patterson L, Irvine N, Wilson A, Doherty L, Loughrey A, Jessop L.

Euro Surveill. 2015 May 28;20(21). pii: 21138.


Immobilization and orientation-dependent activity of a naturally occurring antimicrobial peptide.

Soares JW, Kirby R, Doherty LA, Meehan A, Arcidiacono S.

J Pept Sci. 2015 Aug;21(8):669-79. doi: 10.1002/psc.2787. Epub 2015 May 28.


Carers' needs in advanced heart failure: A systematic narrative review.

Doherty LC, Fitzsimons D, McIlfatrick SJ.

Eur J Cardiovasc Nurs. 2016 Jun;15(4):203-12. doi: 10.1177/1474515115585237. Epub 2015 Apr 28. Review.


How Do I Examine Rigidity and Spasticity?

Fearon C, Doherty L, Lynch T.

Mov Disord Clin Pract. 2015 Mar 28;2(2):204. doi: 10.1002/mdc3.12147. eCollection 2015 Jun.


Can you die from obstructive sleep apnoea syndrome (OSAS)?

O'Carroll G, Doody E, Vaughan C, Doherty L.

Ir Med J. 2015 Feb;108(2):40-3.


Clinical implementation of integrated whole-genome copy number and mutation profiling for glioblastoma.

Ramkissoon SH, Bi WL, Schumacher SE, Ramkissoon LA, Haidar S, Knoff D, Dubuc A, Brown L, Burns M, Cryan JB, Abedalthagafi M, Kang YJ, Schultz N, Reardon DA, Lee EQ, Rinne ML, Norden AD, Nayak L, Ruland S, Doherty LM, LaFrankie DC, Horvath M, Aizer AA, Russo A, Arvold ND, Claus EB, Al-Mefty O, Johnson MD, Golby AJ, Dunn IF, Chiocca EA, Trippa L, Santagata S, Folkerth RD, Kantoff P, Rollins BJ, Lindeman NI, Wen PY, Ligon AH, Beroukhim R, Alexander BM, Ligon KL.

Neuro Oncol. 2015 Oct;17(10):1344-55. doi: 10.1093/neuonc/nov015. Epub 2015 Mar 9.


B(12)-mediated, long wavelength photopolymerization of hydrogels.

Rodgers ZL, Hughes RM, Doherty LM, Shell JR, Molesky BP, Brugh AM, Forbes MD, Moran AM, Lawrence DS.

J Am Chem Soc. 2015 Mar 11;137(9):3372-8. doi: 10.1021/jacs.5b00182. Epub 2015 Feb 27.


Leiomyoma-derived transforming growth factor-β impairs bone morphogenetic protein-2-mediated endometrial receptivity.

Doherty LF, Taylor HS.

Fertil Steril. 2015 Mar;103(3):845-52. doi: 10.1016/j.fertnstert.2014.12.099. Epub 2015 Jan 14.


Phase II study of monthly pasireotide LAR (SOM230C) for recurrent or progressive meningioma.

Norden AD, Ligon KL, Hammond SN, Muzikansky A, Reardon DA, Kaley TJ, Batchelor TT, Plotkin SR, Raizer JJ, Wong ET, Drappatz J, Lesser GJ, Haidar S, Beroukhim R, Lee EQ, Doherty L, Lafrankie D, Gaffey SC, Gerard M, Smith KH, McCluskey C, Phuphanich S, Wen PY.

Neurology. 2015 Jan 20;84(3):280-6. doi: 10.1212/WNL.0000000000001153. Epub 2014 Dec 19.


Garlic revisited: antimicrobial activity of allicin-containing garlic extracts against Burkholderia cepacia complex.

Wallock-Richards D, Doherty CJ, Doherty L, Clarke DJ, Place M, Govan JR, Campopiano DJ.

PLoS One. 2014 Dec 1;9(12):e112726. doi: 10.1371/journal.pone.0112726. eCollection 2014.


Phase II trial of triple tyrosine kinase receptor inhibitor nintedanib in recurrent high-grade gliomas.

Norden AD, Schiff D, Ahluwalia MS, Lesser GJ, Nayak L, Lee EQ, Rinne ML, Muzikansky A, Dietrich J, Purow B, Doherty LM, LaFrankie DC, Pulverenti JR, Rifenburg JA, Ruland SF, Smith KH, Gaffey SC, McCluskey C, Ligon KL, Reardon DA, Wen PY.

J Neurooncol. 2015 Jan;121(2):297-302. doi: 10.1007/s11060-014-1631-y. Epub 2014 Oct 22.


CD133 expression correlates with membrane beta-catenin and E-cadherin loss from human hair follicle placodes during morphogenesis.

Gay DL, Yang CC, Plikus MV, Ito M, Rivera C, Treffeisen E, Doherty L, Spata M, Millar SE, Cotsarelis G.

J Invest Dermatol. 2015 Jan;135(1):45-55. doi: 10.1038/jid.2014.292. Epub 2014 Jul 10.


Retrospective study of carmustine or lomustine with bevacizumab in recurrent glioblastoma patients who have failed prior bevacizumab.

Rahman R, Hempfling K, Norden AD, Reardon DA, Nayak L, Rinne ML, Beroukhim R, Doherty L, Ruland S, Rai A, Rifenburg J, LaFrankie D, Alexander BM, Huang RY, Wen PY, Lee EQ.

Neuro Oncol. 2014 Nov;16(11):1523-9. doi: 10.1093/neuonc/nou118. Epub 2014 Jun 23.

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