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Items: 1 to 50 of 325

1.

DNA released from neutrophil extracellular traps (NETs) activates pancreatic stellate cells and enhances pancreatic tumor growth.

Miller-Ocuin JL, Liang X, Boone BA, Doerfler WR, Singhi AD, Tang D, Kang R, Lotze MT, Zeh HJ 3rd.

Oncoimmunology. 2019 Jun 11;8(9):e1605822. doi: 10.1080/2162402X.2019.1605822. eCollection 2019.

2.

Epigenetic consequences of genome manipulations: caveats for human germline therapy and genetically modified organisms.

Doerfler W.

Epigenomics. 2019 Feb;11(3):247-250. doi: 10.2217/epi-2018-0201. No abstract available.

3.

Inheritable epigenetic response towards foreign DNA entry by mammalian host cells: a guardian of genomic stability.

Doerfler W, Weber S, Naumann A.

Epigenetics. 2018;13(12):1141-1153. doi: 10.1080/15592294.2018.1549463. Epub 2018 Dec 12. Review.

PMID:
30458693
4.

Chloroquine reduces hypercoagulability in pancreatic cancer through inhibition of neutrophil extracellular traps.

Boone BA, Murthy P, Miller-Ocuin J, Doerfler WR, Ellis JT, Liang X, Ross MA, Wallace CT, Sperry JL, Lotze MT, Neal MD, Zeh HJ 3rd.

BMC Cancer. 2018 Jun 22;18(1):678. doi: 10.1186/s12885-018-4584-2.

5.

Intracellular African swine fever virus DNA remains unmethylated in infected Vero cells.

Weber S, Hakobyan A, Zakaryan H, Doerfler W.

Epigenomics. 2018 Mar;10(3):289-299. doi: 10.2217/epi-2017-0131. Epub 2018 Jan 12.

PMID:
29327614
6.

Patho-Epigenetics of Infectious Diseases - Preface.

Doerfler W.

Adv Exp Med Biol. 2016;879:v-vi. No abstract available.

PMID:
27088147
7.

Beware of manipulations on the genome: epigenetic destabilization through (foreign) DNA insertions.

Doerfler W.

Epigenomics. 2016 May;8(5):587-91. doi: 10.2217/epi-2016-0019. Epub 2016 Mar 21. No abstract available.

8.

Individual Health Management - A Comprehensive Lifestyle Counselling Programme for Health Promotion, Disease Prevention and Patient Education.

Melchart D, Eustachi A, Wellenhofer-Li Y, Doerfler W, Bohnes E.

Forsch Komplementmed. 2016;23(1):30-5. doi: 10.1159/000443544. Epub 2016 Jan 27.

9.

DNA methylation and transcription in HERV (K, W, E) and LINE sequences remain unchanged upon foreign DNA insertions.

Weber S, Jung S, Doerfler W.

Epigenomics. 2016 Feb;8(2):157-65. doi: 10.2217/epi.15.109. Epub 2015 Dec 2.

PMID:
26627183
10.

The talent study: a multicentre randomized controlled trial assessing the impact of a 'tailored lifestyle self-management intervention' (talent) on weight reduction.

Melchart D, Doerfler W, Eustachi A, Wellenhofer-Li Y, Weidenhammer W.

BMC Obes. 2015 Oct 1;2:38. doi: 10.1186/s40608-015-0069-x. eCollection 2015.

11.

Destabilization of the human epigenome: consequences of foreign DNA insertions.

Weber S, Hofmann A, Herms S, Hoffmann P, Doerfler W.

Epigenomics. 2015 Aug;7(5):745-55. doi: 10.2217/epi.15.40. Epub 2015 May 18.

12.

Stable DNA methylation boundaries and expanded trinucleotide repeats: role of DNA insertions.

Naumann A, Kraus C, Hoogeveen A, Ramirez CM, Doerfler W.

J Mol Biol. 2014 Jul 15;426(14):2554-66. doi: 10.1016/j.jmb.2014.04.025. Epub 2014 May 6.

PMID:
24816393
13.

Epigenetic analysis of HIV-1 proviral genomes from infected individuals: predominance of unmethylated CpG's.

Weber S, Weiser B, Kemal KS, Burger H, Ramirez CM, Korn K, Anastos K, Kaul R, Kovacs C, Doerfler W.

Virology. 2014 Jan 20;449:181-9. doi: 10.1016/j.virol.2013.11.013. Epub 2013 Dec 5.

14.

Genetic variation in HIF signaling underlies quantitative variation in physiological and life-history traits within lowland butterfly populations.

Marden JH, Fescemyer HW, Schilder RJ, Doerfler WR, Vera JC, Wheat CW.

Evolution. 2013 Apr;67(4):1105-15. doi: 10.1111/evo.12004. Epub 2012 Dec 11.

PMID:
23550759
15.

Impact of foreign DNA integration on tumor biology and on evolution via epigenetic alterations.

Doerfler W.

Epigenomics. 2012 Feb;4(1):41-9. doi: 10.2217/epi.11.111. Review.

PMID:
22332657
16.

Epigenetic consequences of foreign DNA insertions: de novo methylation and global alterations of methylation patterns in recipient genomes.

Doerfler W.

Rev Med Virol. 2011 Nov;21(6):336-46. doi: 10.1002/rmv.698. Epub 2011 Jul 26. Review.

PMID:
21793096
17.

Adenoviruses.

Doerfler W.

In: Baron S, editor. Medical Microbiology. 4th edition. Galveston (TX): University of Texas Medical Branch at Galveston; 1996. Chapter 67.

18.

DNA--a molecule in search of additional functions: recipient of pool wave emissions? A hypothesis.

Doerfler W.

Med Hypotheses. 2010 Sep;75(3):291-3. doi: 10.1016/j.mehy.2010.03.006. Epub 2010 Mar 30.

PMID:
20356684
19.

A distinct DNA-methylation boundary in the 5'- upstream sequence of the FMR1 promoter binds nuclear proteins and is lost in fragile X syndrome.

Naumann A, Hochstein N, Weber S, Fanning E, Doerfler W.

Am J Hum Genet. 2009 Nov;85(5):606-16. doi: 10.1016/j.ajhg.2009.09.018. Epub 2009 Oct 22. Erratum in: Am J Hum Genet. 2010 Jan;86(1):98-100.

20.

Epigenetic mechanisms in human adenovirus type 12 oncogenesis.

Doerfler W.

Semin Cancer Biol. 2009 Jun;19(3):136-43. doi: 10.1016/j.semcancer.2009.02.009. Epub 2009 Feb 20. Review.

PMID:
19429476
21.

In pursuit of the first recognized epigenetic signal--DNA methylation: a 1976 to 2008 synopsis.

Doerfler W.

Epigenetics. 2008 May-Jun;3(3):125-33. Epub 2008 May 7. Review.

PMID:
18487948
22.

Human CAR gene expression in nonpermissive hamster cells boosts entry of type 12 adenovirions and nuclear import of viral DNA.

Hochstein N, Webb D, Hösel M, Seidel W, Auerochs S, Doerfler W.

J Virol. 2008 Apr;82(8):4159-63. doi: 10.1128/JVI.02657-07. Epub 2008 Feb 6.

23.
24.

Nucleotide sequence comparisons between several strains and isolates of human cytomegalovirus reveal alternate start codon usage.

Brondke H, Schmitz B, Doerfler W.

Arch Virol. 2007;152(11):2035-46. Epub 2007 Jul 27.

PMID:
17653620
25.

Epigenetic status of an adenovirus type 12 transgenome upon long-term cultivation in hamster cells.

Hochstein N, Muiznieks I, Mangel L, Brondke H, Doerfler W.

J Virol. 2007 May;81(10):5349-61. Epub 2007 Mar 7.

26.

An origin of DNA replication in the promoter region of the human fragile X mental retardation (FMR1) gene.

Gray SJ, Gerhardt J, Doerfler W, Small LE, Fanning E.

Mol Cell Biol. 2007 Jan;27(2):426-37. Epub 2006 Nov 13.

27.

Thrombophlebitis and upper respiratory tract virus infection.

Doerfler W.

J Med Virol. 2006 Nov;78(11):1505-6.

PMID:
16998877
28.
29.

The almost-forgotten fifth nucleotide in DNA: an introduction.

Doerfler W.

Curr Top Microbiol Immunol. 2006;301:3-18. Review. No abstract available.

PMID:
16570843
30.

Relationships between DNA methylation and expression in erythrocyte membrane protein (band 3, protein 4.2, and beta-spectrin) genes during human erythroid development and differentiation.

Remus R, Kanzaki A, Yawata A, Wada H, Nakanishi H, Sugihara T, Zeschnigk M, Zuther I, Schmitz B, Naumann F, Doerfler W, Yawata Y.

Int J Hematol. 2005 Dec;82(5):422-9.

PMID:
16533746
31.

DNA methylation in promoter regions of red cell membrane protein genes in healthy individuals and patients with hereditary membrane disorders.

Remus R, Kanzaki A, Yawata A, Nakanishi H, Wada H, Sugihara T, Zeschnigk M, Zuther I, Schmitz B, Naumann F, Doerfler W, Yawata Y.

Int J Hematol. 2005 Jun;81(5):385-95.

PMID:
16158818
32.

On the biological significance of DNA methylation.

Doerfler W.

Biochemistry (Mosc). 2005 May;70(5):505-24. Review.

33.

Identification of specific cellular genes up-regulated late in adenovirus type 12 infection.

Dorn A, Zhao H, Granberg F, Hösel M, Webb D, Svensson C, Pettersson U, Doerfler W.

J Virol. 2005 Feb;79(4):2404-12.

34.

Localization of integrated adenovirus DNA in the hamster genome.

Wronka G, Bernardi G, Doerfler W.

Cell Mol Life Sci. 2004 Dec;61(23):2983-90.

PMID:
15583860
35.

Quantitative c-erbB-2 but not c-erbB-1 mRNA expression is a promising marker to predict minor histopathologic response to neoadjuvant radiochemotherapy in oesophageal cancer.

Miyazono F, Metzger R, Warnecke-Eberz U, Baldus SE, Brabender J, Bollschweiler E, Doerfler W, Mueller RP, Dienes HP, Aikou T, Hoelscher AH, Schneider PM.

Br J Cancer. 2004 Aug 16;91(4):666-72.

36.

PCR-screening of human esophageal and bronchial cancers reveals absence of adenoviral DNA sequences.

Mende Y, Schneider PM, Baldus SE, Doerfler W.

Virus Res. 2004 Aug;104(1):81-5.

PMID:
15177895
37.

High specificity of quantitative excision repair cross-complementing 1 messenger RNA expression for prediction of minor histopathological response to neoadjuvant radiochemotherapy in esophageal cancer.

Warnecke-Eberz U, Metzger R, Miyazono F, Baldus SE, Neiss S, Brabender J, Schaefer H, Doerfler W, Bollschweiler E, Dienes HP, Mueller RP, Danenberg PV, Hoelscher AH, Schneider PM.

Clin Cancer Res. 2004 Jun 1;10(11):3794-9.

38.
39.

Tumorigenesis by adenovirus type 12 in newborn Syrian hamsters.

Hohlweg U, Dorn A, Hösel M, Webb D, Buettner R, Doerfler W.

Curr Top Microbiol Immunol. 2004;273:215-44. Review.

PMID:
14674603
40.

Gene structure and expression of the 5'-(CGG)(n)-3'-binding protein (CGGBP1).

Naumann F, Remus R, Schmitz B, Doerfler W.

Genomics. 2004 Jan;83(1):106-18.

PMID:
14667814
41.

Intraperitoneal dissemination of Ad12-induced undifferentiated neuroectodermal hamster tumors: de novo methylation and transcription patterns of integrated viral and of cellular genes.

Hohlweg U, Hösel M, Dorn A, Webb D, Hilger-Eversheim K, Remus R, Schmitz B, Buettner R, Schramme A, Corzilius L, Niemann A, Doerfler W.

Virus Res. 2003 Dec;98(1):45-56.

PMID:
14609629
42.

The gastrointestinal tract as the portal of entry for foreign macromolecules: fate of DNA and proteins.

Palka-Santini M, Schwarz-Herzke B, Hösel M, Renz D, Auerochs S, Brondke H, Doerfler W.

Mol Genet Genomics. 2003 Nov;270(3):201-15. Epub 2003 Aug 23.

PMID:
12938039
43.

Staurosporine is a potent activator of neuronal, glial, and "CNS stem cell-like" neurosphere differentiation in murine embryonic stem cells.

Schumacher A, Arnhold S, Addicks K, Doerfler W.

Mol Cell Neurosci. 2003 Aug;23(4):669-80.

PMID:
12932446
44.

The abortive infection of Syrian hamster cells with human adenovirus type 12.

Hösel M, Webb D, Schröer J, Doerfler W.

Curr Top Microbiol Immunol. 2003;272:415-40. Review.

PMID:
12747558
45.
46.

Amyloglucosidase suppresses interference by glycogen in the quantification of DNA using the Hoechst 33258 dye.

Palka L, Palka-Santini ME, Chambon S, Renz D, Maurer P, Doerfler W.

Biotechniques. 2002 Jun;32(6):1250,1252,1254,1256. No abstract available. Erratum in: Biotechniques. 2002 Sep;33(3):514.

47.

The fate of foreign DNA in mammalian cells and organisms.

Doerfler W, Remus R, Müller K, Heller H, Hohlweg U, Schubbert R.

Dev Biol (Basel). 2001;106:89-97; discussion 143-60.

PMID:
11761272
48.

Foreign DNA integration--perturbations of the genome--oncogenesis.

Doerfler W, Hohlweg U, Müller K, Remus R, Heller H, Hertz J.

Ann N Y Acad Sci. 2001 Sep;945:276-88. Review.

PMID:
11708490
49.

Cellular and early viral factors in the interaction of adenovirus type 12 with hamster cells: the abortive response.

Hösel M, Schröer J, Webb D, Jaroshevskaja E, Doerfler W.

Virus Res. 2001 Dec 4;81(1-2):1-16.

PMID:
11682120
50.

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