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Items: 1 to 50 of 55

1.

No unexpected CRISPR-Cas9 off-target activity revealed by trio sequencing of gene-edited mice.

Iyer V, Boroviak K, Thomas M, Doe B, Riva L, Ryder E, Adams DJ.

PLoS Genet. 2018 Jul 9;14(7):e1007503. doi: 10.1371/journal.pgen.1007503. eCollection 2018 Jul.

2.

Author Correction: Revealing hidden complexities of genomic rearrangements generated with Cas9.

Boroviak K, Fu B, Yang F, Doe B, Bradley A.

Sci Rep. 2018 Apr 5;8(1):5765. doi: 10.1038/s41598-018-23232-6.

3.

Corrigendum: High-throughput discovery of novel developmental phenotypes.

Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie Helmut Fuchs SM, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Nutter SNLMJ, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A; International Mouse Phenotyping Consortium, Wurst W, MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SDM, Adams DJ, Lloyd KCK, McKerlie C, Beaudet AL, Murray MBSA.

Nature. 2017 Nov 16;551(7680):398. doi: 10.1038/nature24643. Epub 2017 Nov 8.

4.

Revealing hidden complexities of genomic rearrangements generated with Cas9.

Boroviak K, Fu B, Yang F, Doe B, Bradley A.

Sci Rep. 2017 Oct 9;7(1):12867. doi: 10.1038/s41598-017-12740-6. Erratum in: Sci Rep. 2018 Apr 5;8(1):5765.

5.

Synthetic lethality between PAXX and XLF in mammalian development.

Balmus G, Barros AC, Wijnhoven PW, Lescale C, Hasse HL, Boroviak K, le Sage C, Doe B, Speak AO, Galli A, Jacobsen M, Deriano L, Adams DJ, Blackford AN, Jackson SP.

Genes Dev. 2016 Oct 1;30(19):2152-2157.

6.

High-throughput discovery of novel developmental phenotypes.

Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A; International Mouse Phenotyping Consortium; Jackson Laboratory; Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource Center, MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA.

Nature. 2016 Sep 22;537(7621):508-514. doi: 10.1038/nature19356. Epub 2016 Sep 14. Erratum in: Nature. 2017 Nov 16;551(7680):398.

7.

C13orf31 (FAMIN) is a central regulator of immunometabolic function.

Cader MZ, Boroviak K, Zhang Q, Assadi G, Kempster SL, Sewell GW, Saveljeva S, Ashcroft JW, Clare S, Mukhopadhyay S, Brown KP, Tschurtschenthaler M, Raine T, Doe B, Chilvers ER, Griffin JL, Kaneider NC, Floto RA, D'Amato M, Bradley A, Wakelam MJ, Dougan G, Kaser A.

Nat Immunol. 2016 Sep;17(9):1046-56. doi: 10.1038/ni.3532. Epub 2016 Aug 1.

PMID:
27478939
8.

Chromosome engineering in zygotes with CRISPR/Cas9.

Boroviak K, Doe B, Banerjee R, Yang F, Bradley A.

Genesis. 2016 Feb;54(2):78-85. doi: 10.1002/dvg.22915. Epub 2016 Jan 25.

9.

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.

de Angelis MH, Nicholson G, Selloum M, White J, Morgan H, Ramirez-Solis R, Sorg T, Wells S, Fuchs H, Fray M, Adams DJ, Adams NC, Adler T, Aguilar-Pimentel A, Ali-Hadji D, Amann G, André P, Atkins S, Auburtin A, Ayadi A, Becker J, Becker L, Bedu E, Bekeredjian R, Birling MC, Blake A, Bottomley J, Bowl M, Brault V, Busch DH, Bussell JN, Calzada-Wack J, Cater H, Champy MF, Charles P, Chevalier C, Chiani F, Codner GF, Combe R, Cox R, Dalloneau E, Dierich A, Di Fenza A, Doe B, Duchon A, Eickelberg O, Esapa CT, El Fertak L, Feigel T, Emelyanova I, Estabel J, Favor J, Flenniken A, Gambadoro A, Garrett L, Gates H, Gerdin AK, Gkoutos G, Greenaway S, Glasl L, Goetz P, Da Cruz IG, Götz A, Graw J, Guimond A, Hans W, Hicks G, Hölter SM, Höfler H, Hancock JM, Hoehndorf R, Hough T, Houghton R, Hurt A, Ivandic B, Jacobs H, Jacquot S, Jones N, Karp NA, Katus HA, Kitchen S, Klein-Rodewald T, Klingenspor M, Klopstock T, Lalanne V, Leblanc S, Lengger C, le Marchand E, Ludwig T, Lux A, McKerlie C, Maier H, Mandel JL, Marschall S, Mark M, Melvin DG, Meziane H, Micklich K, Mittelhauser C, Monassier L, Moulaert D, Muller S, Naton B, Neff F, Nolan PM, Nutter LM, Ollert M, Pavlovic G, Pellegata NS, Peter E, Petit-Demoulière B, Pickard A, Podrini C, Potter P, Pouilly L, Puk O, Richardson D, Rousseau S, Quintanilla-Fend L, Quwailid MM, Racz I, Rathkolb B, Riet F, Rossant J, Roux M, Rozman J, Ryder E, Salisbury J, Santos L, Schäble KH, Schiller E, Schrewe A, Schulz H, Steinkamp R, Simon M, Stewart M, Stöger C, Stöger T, Sun M, Sunter D, Teboul L, Tilly I, Tocchini-Valentini GP, Tost M, Treise I, Vasseur L, Velot E, Vogt-Weisenhorn D, Wagner C, Walling A, Weber B, Wendling O, Westerberg H, Willershäuser M, Wolf E, Wolter A, Wood J, Wurst W, Yildirim AÖ, Zeh R, Zimmer A, Zimprich A; EUMODIC Consortium, Holmes C, Steel KP, Herault Y, Gailus-Durner V, Mallon AM, Brown SD.

Nat Genet. 2015 Sep;47(9):969-978. doi: 10.1038/ng.3360. Epub 2015 Jul 27.

10.

Blastocyst genotyping for quality control of mouse mutant archives: an ethical and economical approach.

Scavizzi F, Ryder E, Newman S, Raspa M, Gleeson D, Wardle-Jones H, Montoliu L, Fernandez A, Dessain ML, Larrigaldie V, Khorshidi Z, Vuolteenaho R, Soininen R, André P, Jacquot S, Hong Y, de Angelis MH, Ramirez-Solis R, Doe B.

Transgenic Res. 2015 Oct;24(5):921-7. doi: 10.1007/s11248-015-9897-1. Epub 2015 Jul 16.

11.

Juno is the egg Izumo receptor and is essential for mammalian fertilization.

Bianchi E, Doe B, Goulding D, Wright GJ.

Nature. 2014 Apr 24;508(7497):483-7. doi: 10.1038/nature13203. Epub 2014 Apr 16.

12.

Rapid conversion of EUCOMM/KOMP-CSD alleles in mouse embryos using a cell-permeable Cre recombinase.

Ryder E, Doe B, Gleeson D, Houghton R, Dalvi P, Grau E, Habib B, Miklejewska E, Newman S, Sethi D, Sinclair C, Vyas S, Wardle-Jones H; Sanger Mouse Genetics Project, Bottomley J, Bussell J, Galli A, Salisbury J, Ramirez-Solis R.

Transgenic Res. 2014 Feb;23(1):177-85. doi: 10.1007/s11248-013-9764-x. Epub 2013 Nov 7.

13.

The mammalian gene function resource: the International Knockout Mouse Consortium.

Bradley A, Anastassiadis K, Ayadi A, Battey JF, Bell C, Birling MC, Bottomley J, Brown SD, Bürger A, Bult CJ, Bushell W, Collins FS, Desaintes C, Doe B, Economides A, Eppig JT, Finnell RH, Fletcher C, Fray M, Frendewey D, Friedel RH, Grosveld FG, Hansen J, Hérault Y, Hicks G, Hörlein A, Houghton R, Hrabé de Angelis M, Huylebroeck D, Iyer V, de Jong PJ, Kadin JA, Kaloff C, Kennedy K, Koutsourakis M, Lloyd KC, Marschall S, Mason J, McKerlie C, McLeod MP, von Melchner H, Moore M, Mujica AO, Nagy A, Nefedov M, Nutter LM, Pavlovic G, Peterson JL, Pollock J, Ramirez-Solis R, Rancourt DE, Raspa M, Remacle JE, Ringwald M, Rosen B, Rosenthal N, Rossant J, Ruiz Noppinger P, Ryder E, Schick JZ, Schnütgen F, Schofield P, Seisenberger C, Selloum M, Simpson EM, Skarnes WC, Smedley D, Stanford WL, Stewart AF, Stone K, Swan K, Tadepally H, Teboul L, Tocchini-Valentini GP, Valenzuela D, West AP, Yamamura K, Yoshinaga Y, Wurst W.

Mamm Genome. 2012 Oct;23(9-10):580-6. doi: 10.1007/s00335-012-9422-2. Epub 2012 Sep 12.

14.

IT systems and third-party products. Do you know who manufactures the components of your system?

Doe B.

J Healthc Inf Manag. 2010 Summer;24(3):17-8. No abstract available.

PMID:
20677467
15.

My license agreement says what? Have the appropriate license rights in your software license agreements.

Doe B.

J Healthc Inf Manag. 2010 Spring;24(2):17-8. No abstract available.

PMID:
20397328
16.

HITECH notice requirements for breach of unsecured PHI. What changes apply to you and your organization?

Doe B.

J Healthc Inf Manag. 2010 Winter;24(1):15-6. No abstract available.

PMID:
20077920
17.

HITECH meets HIPAA. HITECH Act changes to HIPAA obligations for covered entities and business associates.

Doe B.

J Healthc Inf Manag. 2009 Fall;23(4):15-6. No abstract available.

PMID:
19894481
18.

Crunching the numbers: how the economy can save you money on IT transactions.

Doe B.

J Healthc Inf Manag. 2009 Summer;23(3):18-9. No abstract available.

PMID:
19663159
19.

Negotiating application service provider agreements. Understanding the upsides and downsides of ASPs.

Doe B.

J Healthc Inf Manag. 2008 Fall;22(4):19-20. No abstract available.

PMID:
19267014
20.

Genomic DNA damage in mouse transgenesis.

Yamauchi Y, Doe B, Ajduk A, Ward MA.

Biol Reprod. 2007 Nov;77(5):803-12. Epub 2007 Jul 25.

PMID:
17652664
21.

Evaluation of human immunodeficiency virus type 1 subtype C gag, pol, and gagpol DNA and alphavirus replicon vaccines.

Megede JZ, Otten GR, Doe B, Liu H, Srivastava R, Greer C, Legg H, Tang T, Polo JM, Donnelly JJ, Ulmer JB, Barnett SW.

Vaccine. 2006 Apr 5;24(15):2755-63. Epub 2006 Jan 19.

PMID:
16460840
22.

Potent immunogenicity of an HIV-1 gag-pol fusion DNA vaccine delivered by in vivo electroporation.

Otten GR, Schaefer M, Doe B, Liu H, Megede JZ, Donnelly J, Rabussay D, Barnett S, Ulmer JB.

Vaccine. 2006 May 22;24(21):4503-9. Epub 2005 Aug 19.

PMID:
16181711
23.

Enhanced potency of plasmid DNA microparticle human immunodeficiency virus vaccines in rhesus macaques by using a priming-boosting regimen with recombinant proteins.

Otten GR, Schaefer M, Doe B, Liu H, Srivastava I, Megede Jz, Kazzaz J, Lian Y, Singh M, Ugozzoli M, Montefiori D, Lewis M, Driver DA, Dubensky T, Polo JM, Donnelly J, O'Hagan DT, Barnett S, Ulmer JB.

J Virol. 2005 Jul;79(13):8189-200.

24.

Enhancement of DNA vaccine potency in rhesus macaques by electroporation.

Otten G, Schaefer M, Doe B, Liu H, Srivastava I, zur Megede J, O'Hagan D, Donnelly J, Widera G, Rabussay D, Lewis MG, Barnett S, Ulmer JB.

Vaccine. 2004 Jun 23;22(19):2489-93.

PMID:
15193413
25.

An alphavirus replicon particle chimera derived from venezuelan equine encephalitis and sindbis viruses is a potent gene-based vaccine delivery vector.

Perri S, Greer CE, Thudium K, Doe B, Legg H, Liu H, Romero RE, Tang Z, Bin Q, Dubensky TW Jr, Vajdy M, Otten GR, Polo JM.

J Virol. 2003 Oct;77(19):10394-403.

26.

Expression and immunogenicity of sequence-modified human immunodeficiency virus type 1 subtype B pol and gagpol DNA vaccines.

zur Megede J, Otten GR, Doe B, Liu H, Leung L, Ulmer JB, Donnelly JJ, Barnett SW.

J Virol. 2003 Jun;77(11):6197-207.

27.

Quantitative assessment of antigen-specific CD8+ T cells in the mouse: application to vaccine research.

Otten GR, Chen M, Doe B, zur Megede J, Barnett S, Ulmer J.

Immunol Lett. 2003 Jan 22;85(2):215-22.

PMID:
12527230
28.

New 3' elements control Pax6 expression in the developing pretectum, neural retina and olfactory region.

Griffin C, Kleinjan DA, Doe B, van Heyningen V.

Mech Dev. 2002 Mar;112(1-2):89-100.

29.

Induction of potent immune responses by cationic microparticles with adsorbed human immunodeficiency virus DNA vaccines.

O'Hagan D, Singh M, Ugozzoli M, Wild C, Barnett S, Chen M, Schaefer M, Doe B, Otten GR, Ulmer JB.

J Virol. 2001 Oct;75(19):9037-43.

30.

Induction of herpes simplex virus gB-specific cytotoxic T lymphocytes in TAP1-deficient mice by genetic immunization but not HSV infection.

Paliard X, Doe B, Selby MJ, Hartog K, Lee AY, Burke RL, Walker CM.

Virology. 2001 Mar 30;282(1):56-64.

31.

Relative potency of cellular and humoral immune responses induced by DNA vaccination.

Otten GR, Doe B, Schaefer M, Chen M, Selby MJ, Goldbeck C, Hong M, Xu F, Ulmer JB.

Intervirology. 2000;43(4-6):227-32.

PMID:
11251378
32.

Plasmid DNA adsorbed onto cationic microparticles mediates target gene expression and antigen presentation by dendritic cells.

Denis-Mize KS, Dupuis M, MacKichan ML, Singh M, Doe B, O'Hagan D, Ulmer JB, Donnelly JJ, McDonald DM, Ott G.

Gene Ther. 2000 Dec;7(24):2105-12.

33.

Increased expression and immunogenicity of sequence-modified human immunodeficiency virus type 1 gag gene.

zur Megede J, Chen MC, Doe B, Schaefer M, Greer CE, Selby M, Otten GR, Barnett SW.

J Virol. 2000 Mar;74(6):2628-35.

34.

Prime-boost immunization strategies against HIV.

Barnett SW, Klinger JM, Doe B, Walker CM, Hansen L, Duliège AM, Sinangil FM.

AIDS Res Hum Retroviruses. 1998 Oct;14 Suppl 3:S299-309. Review. No abstract available.

PMID:
9814958
35.

The T cell repertoire primed by antiviral vaccination is influenced by self-tolerance.

Paliard X, Doe B, Walker CM.

Cell Immunol. 1998 Aug 25;188(1):73-9.

PMID:
9743560
37.

Vaccination with HIV-1 gp120 DNA induces immune responses that are boosted by a recombinant gp120 protein subunit.

Barnett SW, Rajasekar S, Legg H, Doe B, Fuller DH, Haynes JR, Walker CM, Steimer KS.

Vaccine. 1997 Jun;15(8):869-73.

PMID:
9234536
38.

Urban equity and urban health: using existing data to understand inequalities in health and environment in Accra, Ghana and Sao Paulo, Brazil.

Stephens C, Akerman M, Avle S, Maia PB, Campanario P, Doe B, Tetteh D.

Environ Urban. 1997 Apr;9(1):181-202.

PMID:
12293192
39.

Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells.

Doe B, Selby M, Barnett S, Baenziger J, Walker CM.

Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8578-83.

40.

HIV-1 p24 Gag-specific cytotoxic T-lymphocyte responses in mice.

Doe B, Walker CM.

AIDS. 1996 Jun;10(7):793-4. No abstract available.

PMID:
8805872
42.

Expression of a homologously recombined erythopoietin-SV40 T antigen fusion gene in mouse liver: evidence for erythropoietin production by Ito cells.

Maxwell PH, Ferguson DJ, Osmond MK, Pugh CW, Heryet A, Doe BG, Johnson MH, Ratcliffe PJ.

Blood. 1994 Sep 15;84(6):1823-30.

43.

Androgenesis and gynogenesis are not causative in early pregnancy loss in humans.

Hsu CC, McConnell J, Doe B, Braude P.

Am J Obstet Gynecol. 1994 May;170(5 Pt 1):1351-8.

PMID:
8178865
44.

Erythropoietin-producing cells in transgenic mice expressing SV40 large T antigen directed by erythropoietin control sequences.

Maxwell PH, Osmond MK, Pugh CW, Heryet A, Nicholls LG, Tan CC, Doe BG, Ferguson DJ, Johnson MH, Ratcliffe PJ.

Ann N Y Acad Sci. 1994 Apr 15;718:356-8. No abstract available.

PMID:
8185246
45.

Identification of the renal erythropoietin-producing cells using transgenic mice.

Maxwell PH, Osmond MK, Pugh CW, Heryet A, Nicholls LG, Tan CC, Doe BG, Ferguson DJ, Johnson MH, Ratcliffe PJ.

Kidney Int. 1993 Nov;44(5):1149-62.

46.

HeLa-LAV, an epithelial cell line stably infected with HIV-1.

Berg J, Doe B, Steimer KS, Wabl M.

J Virol Methods. 1991 Sep-Oct;34(2):173-80.

PMID:
1687144
47.
48.

Immunospecific vesicle targeting facilitates fusion with selected cell populations.

Guyden J, Godfrey W, Doe B, Ousley F, Wofsy L.

Ciba Found Symp. 1984;103:239-53.

PMID:
6561136
49.

Immunospecific vesicle targeting facilitates microinjection into lymphocytes.

Godfrey W, Doe B, Wofsy L.

Proc Natl Acad Sci U S A. 1983 Apr;80(8):2267-71.

50.

Affinity targeting of membrane vesicles to cell surfaces.

Godfrey W, Doe B, Wallace EF, Bredt B, Wofsy L.

Exp Cell Res. 1981 Sep;135(1):137-45. No abstract available.

PMID:
7026265

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