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Items: 1 to 50 of 171

1.

Early enrichment of ESR1 mutations and the impact on gene expression in pre-surgical primary breast cancer treated with aromatase inhibitors.

Leal MF, Haynes BP, Schuster EF, Yeo B, Afentakis M, Zabaglo L, Martins V, Buus R, Dodson A, Cheang MCU, Smith IE, Martin LA, Dowsett M.

Clin Cancer Res. 2019 Sep 23. pii: clincanres.1129.2019. doi: 10.1158/1078-0432.CCR-19-1129. [Epub ahead of print]

PMID:
31548345
2.

Germ Granules Coordinate RNA-Based Epigenetic Inheritance Pathways.

Dodson AE, Kennedy S.

Dev Cell. 2019 Sep 23;50(6):704-715.e4. doi: 10.1016/j.devcel.2019.07.025. Epub 2019 Aug 8.

PMID:
31402284
3.

Ion friction at small values of the Coulomb logarithm.

Sprenkle T, Dodson A, McKnight Q, Spencer R, Bergeson S, Diaw A, Murillo MS.

Phys Rev E. 2019 May;99(5-1):053206. doi: 10.1103/PhysRevE.99.053206.

PMID:
31212549
4.

Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicentre collaboration.

Leung SCY, Nielsen TO, Zabaglo LA, Arun I, Badve SS, Bane AL, Bartlett JMS, Borgquist S, Chang MC, Dodson A, Ehinger A, Fineberg S, Focke CM, Gao D, Gown AM, Gutierrez C, Hugh JC, Kos Z, Laenkholm AV, Mastropasqua MG, Moriya T, Nofech-Mozes S, Osborne CK, Penault-Llorca FM, Piper T, Sakatani T, Salgado R, Starczynski J, Sugie T, van der Vegt B, Viale G, Hayes DF, McShane LM, Dowsett M; International Ki67 in Breast Cancer Working Group of the Breast International Group and North American Breast Cancer Group (BIG-NABCG).

Histopathology. 2019 Aug;75(2):225-235. doi: 10.1111/his.13880. Epub 2019 Jul 8.

PMID:
31017314
5.

Anti-metastatic effect of ranolazine in an in vivo rat model of prostate cancer, and expression of voltage-gated sodium channel protein in human prostate.

Bugan I, Kucuk S, Karagoz Z, Fraser SP, Kaya H, Dodson A, Foster CS, Altun S, Djamgoz MBA.

Prostate Cancer Prostatic Dis. 2019 Mar 20. doi: 10.1038/s41391-019-0128-3. [Epub ahead of print]

PMID:
30894674
6.

Comparison of protein expression between formalin-fixed core-cut biopsies and surgical excision specimens using a novel multiplex approach.

Leal MF, Haynes BP, MacNeill FA, Dodson A, Dowsett M.

Breast Cancer Res Treat. 2019 Jun;175(2):317-326. doi: 10.1007/s10549-019-05163-6. Epub 2019 Feb 22.

7.

Simulation of a Spontaneous Vaginal Delivery and Neonatal Resuscitation in a Biocontainment Unit.

Kogutt BK, Sheffield JS, Whyne D, Maragakis LL, Andonian J, Flinn J, Sulmonte C, Dodson A, Romig M, Sauer L, Maloney R, Ferrell J, Vaught AJ, Golden WC, Garibaldi BT.

Health Secur. 2019 Jan/Feb;17(1):18-26. doi: 10.1089/hs.2018.0090.

PMID:
30779606
8.

Randomized Phase II Study Evaluating Palbociclib in Addition to Letrozole as Neoadjuvant Therapy in Estrogen Receptor-Positive Early Breast Cancer: PALLET Trial.

Johnston S, Puhalla S, Wheatley D, Ring A, Barry P, Holcombe C, Boileau JF, Provencher L, Robidoux A, Rimawi M, McIntosh SA, Shalaby I, Stein RC, Thirlwell M, Dolling D, Morden J, Snowdon C, Perry S, Cornman C, Batten LM, Jeffs LK, Dodson A, Martins V, Modi A, Osborne CK, Pogue-Geile KL, Cheang MCU, Wolmark N, Julian TB, Fisher K, MacKenzie M, Wilcox M, Huang Bartlett C, Koehler M, Dowsett M, Bliss JM, Jacobs SA.

J Clin Oncol. 2019 Jan 20;37(3):178-189. doi: 10.1200/JCO.18.01624. Epub 2018 Dec 6.

PMID:
30523750
9.

Breast cancer biomarkers in clinical testing: analysis of a UK national external quality assessment scheme for immunocytochemistry and in situ hybridisation database containing results from 199 300 patients.

Dodson A, Parry S, Ibrahim M, Bartlett JM, Pinder S, Dowsett M, Miller K.

J Pathol Clin Res. 2018 Oct;4(4):262-273. doi: 10.1002/cjp2.112. Epub 2018 Sep 21.

10.

Major Impact of Sampling Methodology on Gene Expression in Estrogen Receptor-Positive Breast Cancer.

Gao Q, López-Knowles E, U Cheang MC, Morden J, Ribas R, Sidhu K, Evans D, Martins V, Dodson A, Skene A, Holcombe C, Mallon E, Evans A, Bliss JM, Robertson J, Smith I, Martin LA, Dowsett M; POETIC Trial Management Group and Trialists.

JNCI Cancer Spectr. 2018 May 22;2(2):pky005. doi: 10.1093/jncics/pky005. eCollection 2018 Apr.

11.

Integration of Clinical Variables for the Prediction of Late Distant Recurrence in Patients With Estrogen Receptor-Positive Breast Cancer Treated With 5 Years of Endocrine Therapy: CTS5.

Dowsett M, Sestak I, Regan MM, Dodson A, Viale G, Thürlimann B, Colleoni M, Cuzick J.

J Clin Oncol. 2018 Jul 1;36(19):1941-1948. doi: 10.1200/JCO.2017.76.4258. Epub 2018 Apr 20.

12.

Discordance between oncotype DX recurrence score and RSPC for predicting residual risk of recurrence in ER-positive breast cancer.

Dodson A, Okonji D, Assersohn L, Rigg A, Sheri A, Turner N, Smith I, Parton M, Dowsett M.

Breast Cancer Res Treat. 2018 Feb;168(1):249-258. doi: 10.1007/s10549-017-4514-z. Epub 2017 Nov 11.

13.

School absence and its effect on school performance for children born with orofacial clefts.

Bell J, Raynes-Greenow C, Turner R, Bower C, Dodson A, Hancock K, Nassar N.

Birth Defects Res. 2017 Jul 17;109(13):1048-1056. doi: 10.1002/bdr2.1041. Epub 2017 Jun 1.

14.

Embryonic transcription factor SOX9 drives breast cancer endocrine resistance.

Jeselsohn R, Cornwell M, Pun M, Buchwalter G, Nguyen M, Bango C, Huang Y, Kuang Y, Paweletz C, Fu X, Nardone A, De Angelis C, Detre S, Dodson A, Mohammed H, Carroll JS, Bowden M, Rao P, Long HW, Li F, Dowsett M, Schiff R, Brown M.

Proc Natl Acad Sci U S A. 2017 May 30;114(22):E4482-E4491. doi: 10.1073/pnas.1620993114. Epub 2017 May 15.

15.

Acrylamide-forming potential of potatoes grown at different locations, and the ratio of free asparagine to reducing sugars at which free asparagine becomes a limiting factor for acrylamide formation.

Muttucumaru N, Powers SJ, Elmore JS, Dodson A, Briddon A, Mottram DS, Halford NG.

Food Chem. 2017 Apr 1;220:76-86. doi: 10.1016/j.foodchem.2016.09.199. Epub 2016 Sep 30.

16.

Impact of mutational profiles on response of primary oestrogen receptor-positive breast cancers to oestrogen deprivation.

Gellert P, Segal CV, Gao Q, López-Knowles E, Martin LA, Dodson A, Li T, Miller CA, Lu C, Mardis ER, Gillman A, Morden J, Graf M, Sidhu K, Evans A, Shere M, Holcombe C, McIntosh SA, Bundred N, Skene A, Maxwell W, Robertson J, Bliss JM, Smith I, Dowsett M; POETIC Trial Management Group and Trialists.

Nat Commun. 2016 Nov 9;7:13294. doi: 10.1038/ncomms13294.

17.

Donor Preference Meets Heterochromatin: Moonlighting Activities of a Recombinational Enhancer in Saccharomyces cerevisiae.

Dodson AE, Rine J.

Genetics. 2016 Nov;204(3):1065-1074. doi: 10.1534/genetics.116.194696. Epub 2016 Sep 21.

18.

School performance for children with cleft lip and palate: a population-based study.

Bell JC, Raynes-Greenow C, Turner R, Bower C, Dodson A, Nicholls W, Nassar N.

Child Care Health Dev. 2017 Mar;43(2):222-231. doi: 10.1111/cch.12388. Epub 2016 Aug 8.

19.

Histone Deacetylases with Antagonistic Roles in Saccharomyces cerevisiae Heterochromatin Formation.

Thurtle-Schmidt DM, Dodson AE, Rine J.

Genetics. 2016 Sep;204(1):177-90. doi: 10.1534/genetics.116.190835. Epub 2016 Aug 3.

20.

LEARNING BY DOING: Johns Hopkins expands sim center to meet growing demand.

Dodson A, Stone VC.

Health Facil Manage. 2016 Apr;29(4):29-32. No abstract available.

PMID:
27209886
21.

Analytical validation of a standardized scoring protocol for Ki67: phase 3 of an international multicenter collaboration.

Leung SCY, Nielsen TO, Zabaglo L, Arun I, Badve SS, Bane AL, Bartlett JMS, Borgquist S, Chang MC, Dodson A, Enos RA, Fineberg S, Focke CM, Gao D, Gown AM, Grabau D, Gutierrez C, Hugh JC, Kos Z, Lænkholm AV, Lin MG, Mastropasqua MG, Moriya T, Nofech-Mozes S, Osborne CK, Penault-Llorca FM, Piper T, Sakatani T, Salgado R, Starczynski J, Viale G, Hayes DF, McShane LM, Dowsett M.

NPJ Breast Cancer. 2016 May 18;2:16014. doi: 10.1038/npjbcancer.2016.14. eCollection 2016.

22.

An Assessment Tool for the Placement of Ultrasound-Guided Peripheral Intravenous Access.

Rice J, Crichlow A, Baker M, Regan L, Dodson A, Hsieh YH, Omron R.

J Grad Med Educ. 2016 May;8(2):202-7. doi: 10.4300/JGME-D-15-00298.1.

23.

Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening.

Woolford AJ, Pero JE, Aravapalli S, Berdini V, Coyle JE, Day PJ, Dodson AM, Grondin P, Holding FP, Lee LY, Li P, Manas ES, Marino J Jr, Martin AC, McCleland BW, McMenamin RL, Murray CW, Neipp CE, Page LW, Patel VK, Potvain F, Rich S, Rivero RA, Smith K, Somers DO, Trottet L, Velagaleti R, Williams G, Xie R.

J Med Chem. 2016 Jun 9;59(11):5356-67. doi: 10.1021/acs.jmedchem.6b00212. Epub 2016 May 20.

PMID:
27167608
24.

Riches of phenotype computationally extracted from microbial colonies.

Liu TY, Dodson AE, Terhorst J, Song YS, Rine J.

Proc Natl Acad Sci U S A. 2016 May 17;113(20):E2822-31. doi: 10.1073/pnas.1523295113. Epub 2016 May 2.

25.

Heterogeneity in global gene expression profiles between biopsy specimens taken peri-surgically from primary ER-positive breast carcinomas.

López-Knowles E, Gao Q, Cheang MC, Morden J, Parker J, Martin LA, Pinhel I, McNeill F, Hills M, Detre S, Afentakis M, Zabaglo L, Dodson A, Skene A, Holcombe C, Robertson J, Smith I, Bliss JM, Dowsett M; POETIC trialists.

Breast Cancer Res. 2016 Apr 1;18(1):39. doi: 10.1186/s13058-016-0696-2.

26.

Transcriptome sequencing of human breast cancer reveals aberrant intronic transcription in amplicons and dysregulation of alternative splicing with major therapeutic implications.

Forootan SS, Butler JM, Gardener D, Jones D, Baird AE, Dodson A, Darby A, Kenny J, Hall N, Cossins AR, Foster CS, Gosden CM.

Int J Oncol. 2016 Jan;48(1):130-44. doi: 10.3892/ijo.2015.3222. Epub 2015 Oct 30. Erratum in: Int J Oncol. 2017 Sep;51(3):997-0.

PMID:
26530297
27.

Insights into genetic alterations of liver metastases from uveal melanoma.

McCarthy C, Kalirai H, Lake SL, Dodson A, Damato BE, Coupland SE.

Pigment Cell Melanoma Res. 2016 Jan;29(1):60-7. doi: 10.1111/pcmr.12433.

PMID:
26523470
28.

Metabolism and epigenetics.

Janke R, Dodson AE, Rine J.

Annu Rev Cell Dev Biol. 2015;31:473-496. doi: 10.1146/annurev-cellbio-100814-125544. Epub 2015 Sep 10. Review.

29.

Risk of recurrence estimates with IHC4+C are tolerant of variations in staining and scoring: an analytical validity study.

Dodson A, Zabaglo L, Yeo B, Miller K, Smith I, Dowsett M.

J Clin Pathol. 2016 Feb;69(2):128-35. doi: 10.1136/jclinpath-2015-203212. Epub 2015 Aug 17.

PMID:
26281860
30.

Clinical utility of the IHC4+C score in oestrogen receptor-positive early breast cancer: a prospective decision impact study.

Yeo B, Zabaglo L, Hills M, Dodson A, Smith I, Dowsett M.

Br J Cancer. 2015 Jul 28;113(3):390-5. doi: 10.1038/bjc.2015.222. Epub 2015 Jul 16.

31.

Acrylamide in potato crisps prepared from 20 UK-grown varieties: effects of variety and tuber storage time.

Elmore JS, Briddon A, Dodson AT, Muttucumaru N, Halford NG, Mottram DS.

Food Chem. 2015 Sep 1;182:1-8. doi: 10.1016/j.foodchem.2015.02.103. Epub 2015 Feb 26.

32.

Heritable capture of heterochromatin dynamics in Saccharomyces cerevisiae.

Dodson AE, Rine J.

Elife. 2015 Jan 12;4:e05007. doi: 10.7554/eLife.05007.

33.

Lack of BAP1 protein expression in uveal melanoma is associated with increased metastatic risk and has utility in routine prognostic testing.

Kalirai H, Dodson A, Faqir S, Damato BE, Coupland SE.

Br J Cancer. 2014 Sep 23;111(7):1373-80. doi: 10.1038/bjc.2014.417. Epub 2014 Jul 24.

34.

Authors’ reply.

Lake SL, Kalirai H, Dodson AR, Coupland SE, Lloyd BH, Damato BE, Taktak AF.

Am J Pathol. 2013 Aug;183(2):638-40. No abstract available.

PMID:
24049776
35.

Technical note: a novel approach to the detection of estrus in dairy cows using ultra-wideband technology.

Homer EM, Gao Y, Meng X, Dodson A, Webb R, Garnsworthy PC.

J Dairy Sci. 2013 Oct;96(10):6529-34. doi: 10.3168/jds.2013-6747. Epub 2013 Aug 1.

36.

Improvement in the quality of molecular analysis of EGFR in non-small-cell lung cancer detected by three rounds of external quality assessment.

Deans ZC, Bilbe N, O'Sullivan B, Lazarou LP, de Castro DG, Parry S, Dodson A, Taniere P, Clark C, Butler R.

J Clin Pathol. 2013 Apr;66(4):319-25. doi: 10.1136/jclinpath-2012-201227. Epub 2013 Feb 1.

PMID:
23378269
37.

Single nucleotide polymorphism array analysis of uveal melanomas reveals that amplification of CNKSR3 is correlated with improved patient survival.

Lake SL, Damato BE, Kalirai H, Dodson AR, Taktak AF, Lloyd BH, Coupland SE.

Am J Pathol. 2013 Mar;182(3):678-87. doi: 10.1016/j.ajpath.2012.11.036. Epub 2013 Jan 26.

PMID:
23357503
38.

Intraocular collision tumour: case report and literature review.

Coupland SE, Dodson A, Liu H, Du MQ, Angi M, Damato BE.

Graefes Arch Clin Exp Ophthalmol. 2013 May;251(5):1383-8. doi: 10.1007/s00417-012-2216-0. Epub 2012 Dec 12. Review.

PMID:
23232651
39.

Splice variant PRKC-ζ(-PrC) is a novel biomarker of human prostate cancer.

Yao S, Ireland SJ, Bee A, Beesley C, Forootan SS, Dodson A, Dickinson T, Gerard P, Lian LY, Risk JM, Smith P, Malki MI, Ke Y, Cooper CS, Gosden C, Foster CS.

Br J Cancer. 2012 Jul 10;107(2):388-99. doi: 10.1038/bjc.2012.162. Epub 2012 May 29.

40.

Morphology and antigen expression profile of pulmonary neuroendocrine cells in reactive proliferations and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH).

Gosney JR, Williams IJ, Dodson AR, Foster CS.

Histopathology. 2011 Oct;59(4):751-62. doi: 10.1111/j.1365-2559.2011.03992.x.

PMID:
22014055
41.

siRNA knockdown of ribosomal protein gene RPL19 abrogates the aggressive phenotype of human prostate cancer.

Bee A, Brewer D, Beesley C, Dodson A, Forootan S, Dickinson T, Gerard P, Lane B, Yao S, Cooper CS, Djamgoz MB, Gosden CM, Ke Y, Foster CS.

PLoS One. 2011;6(7):e22672. doi: 10.1371/journal.pone.0022672. Epub 2011 Jul 22.

42.

The TRIM5 gene modulates penile mucosal acquisition of simian immunodeficiency virus in rhesus monkeys.

Yeh WW, Rao SS, Lim SY, Zhang J, Hraber PT, Brassard LM, Luedemann C, Todd JP, Dodson A, Shen L, Buzby AP, Whitney JB, Korber BT, Nabel GJ, Mascola JR, Letvin NL.

J Virol. 2011 Oct;85(19):10389-98. doi: 10.1128/JVI.00854-11. Epub 2011 Jul 20.

43.

Combined p53 and MDM2 biomarker analysis shows a unique pattern of expression associated with poor prognosis in patients with renal cell carcinoma undergoing radical nephrectomy.

Noon AP, Polański R, El-Fert AY, Kalirai H, Shawki H, Campbell F, Dodson A, Eccles RM, Lloyd BH, Sibson DR, Coupland SE, Lake SL, Parsons K, Vlatković N, Boyd MT.

BJU Int. 2012 Apr;109(8):1250-7. doi: 10.1111/j.1464-410X.2011.10433.x. Epub 2011 Jul 14.

44.

Loss of MTBP expression is associated with reduced survival in a biomarker-defined subset of patients with squamous cell carcinoma of the head and neck.

Vlatković N, El-Fert A, Devling T, Ray-Sinha A, Gore DM, Rubbi CP, Dodson A, Jones AS, Helliwell TR, Jones TM, Boyd MT.

Cancer. 2011 Jul 1;117(13):2939-50. doi: 10.1002/cncr.25864. Epub 2011 Jan 10.

45.

Changes in calcineurin message, enzyme activity and protein content in the spinal dorsal horn are associated with chronic constriction injury of the rat sciatic nerve.

Miletic G, Sullivan KM, Dodson AM, Lippitt JA, Schneider JA, Miletic V.

Neuroscience. 2011 Aug 11;188:142-7. doi: 10.1016/j.neuroscience.2011.05.013. Epub 2011 May 13.

46.

Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys.

Letvin NL, Rao SS, Montefiori DC, Seaman MS, Sun Y, Lim SY, Yeh WW, Asmal M, Gelman RS, Shen L, Whitney JB, Seoighe C, Lacerda M, Keating S, Norris PJ, Hudgens MG, Gilbert PB, Buzby AP, Mach LV, Zhang J, Balachandran H, Shaw GM, Schmidt SD, Todd JP, Dodson A, Mascola JR, Nabel GJ.

Sci Transl Med. 2011 May 4;3(81):81ra36. doi: 10.1126/scitranslmed.3002351.

47.

The proteomics of quiescent and nonquiescent cell differentiation in yeast stationary-phase cultures.

Davidson GS, Joe RM, Roy S, Meirelles O, Allen CP, Wilson MR, Tapia PH, Manzanilla EE, Dodson AE, Chakraborty S, Carter M, Young S, Edwards B, Sklar L, Werner-Washburne M.

Mol Biol Cell. 2011 Apr;22(7):988-98. doi: 10.1091/mbc.E10-06-0499. Epub 2011 Feb 2.

48.

Antigenotoxic effect of kefir and ayran supernatants on fecal water-induced DNA damage in human colon cells.

Grishina A, Kulikova I, Alieva L, Dodson A, Rowland I, Jin J.

Nutr Cancer. 2011;63(1):73-9. doi: 10.1080/01635581.2010.516873.

PMID:
21161824
49.

Low molecular weight heat shock protein HSP27 is a prognostic indicator in rectal cancer but not colon cancer.

Tweedle EM, Khattak I, Ang CW, Nedjadi T, Jenkins R, Park BK, Kalirai H, Dodson A, Azadeh B, Terlizzo M, Grabsch H, Mueller W, Myint S, Clark P, Wong H, Greenhalf W, Neoptolemos JP, Rooney PS, Costello E.

Gut. 2010 Nov;59(11):1501-10. doi: 10.1136/gut.2009.196626.

PMID:
20947885
50.

Smad4 loss is associated with fewer S100A8-positive monocytes in colorectal tumors and attenuated response to S100A8 in colorectal and pancreatic cancer cells.

Ang CW, Nedjadi T, Sheikh AA, Tweedle EM, Tonack S, Honap S, Jenkins RE, Park BK, Schwarte-Waldhoff I, Khattak I, Azadeh B, Dodson A, Kalirai H, Neoptolemos JP, Rooney PS, Costello E.

Carcinogenesis. 2010 Sep;31(9):1541-51. doi: 10.1093/carcin/bgq137. Epub 2010 Jul 9.

PMID:
20622003

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