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Items: 22


Motor-cargo adaptors at the organelle-cytoskeleton interface.

Cross JA, Dodding MP.

Curr Opin Cell Biol. 2019 Aug;59:16-23. doi: 10.1016/ Epub 2019 Apr 2. Review.


Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors.

Pernigo S, Chegkazi MS, Yip YY, Treacy C, Glorani G, Hansen K, Politis A, Bui S, Dodding MP, Steiner RA.

Elife. 2018 Oct 15;7. pii: e38362. doi: 10.7554/eLife.38362.


A small-molecule activator of kinesin-1 drives remodeling of the microtubule network.

Randall TS, Yip YY, Wallock-Richards DJ, Pfisterer K, Sanger A, Ficek W, Steiner RA, Beavil AJ, Parsons M, Dodding MP.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13738-13743. doi: 10.1073/pnas.1715115115. Epub 2017 Dec 11.


SKIP controls lysosome positioning using a composite kinesin-1 heavy and light chain-binding domain.

Sanger A, Yip YY, Randall TS, Pernigo S, Steiner RA, Dodding MP.

J Cell Sci. 2017 May 1;130(9):1637-1651. doi: 10.1242/jcs.198267. Epub 2017 Mar 16.


Folliculin - A tumor suppressor at the intersection of metabolic signaling and membrane traffic.

Dodding MP.

Small GTPases. 2017 Apr 3;8(2):100-105. doi: 10.1080/21541248.2016.1204808. Epub 2016 Jun 29. Review.


The Dynamic Localization of Cytoplasmic Dynein in Neurons Is Driven by Kinesin-1.

Twelvetrees AE, Pernigo S, Sanger A, Guedes-Dias P, Schiavo G, Steiner RA, Dodding MP, Holzbaur EL.

Neuron. 2016 Jun 1;90(5):1000-15. doi: 10.1016/j.neuron.2016.04.046. Epub 2016 May 19.


Folliculin directs the formation of a Rab34-RILP complex to control the nutrient-dependent dynamic distribution of lysosomes.

Starling GP, Yip YY, Sanger A, Morton PE, Eden ER, Dodding MP.

EMBO Rep. 2016 Jun;17(6):823-41. doi: 10.15252/embr.201541382. Epub 2016 Apr 13.


The light chains of kinesin-1 are autoinhibited.

Yip YY, Pernigo S, Sanger A, Xu M, Parsons M, Steiner RA, Dodding MP.

Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):2418-23. doi: 10.1073/pnas.1520817113. Epub 2016 Feb 16.


Backseat drivers: Regulation of dynein motility.

Dodding MP.

Cell Res. 2014 Dec;24(12):1385-6. doi: 10.1038/cr.2014.115. Epub 2014 Aug 22.


Vaccinia virus F11 promotes viral spread by acting as a PDZ-containing scaffolding protein to bind myosin-9A and inhibit RhoA signaling.

Handa Y, Durkin CH, Dodding MP, Way M.

Cell Host Microbe. 2013 Jul 17;14(1):51-62. doi: 10.1016/j.chom.2013.06.006.


Structural basis for kinesin-1:cargo recognition.

Pernigo S, Lamprecht A, Steiner RA, Dodding MP.

Science. 2013 Apr 19;340(6130):356-9. doi: 10.1126/science.1234264. Epub 2013 Mar 21.


Clathrin potentiates vaccinia-induced actin polymerization to facilitate viral spread.

Humphries AC, Dodding MP, Barry DJ, Collinson LM, Durkin CH, Way M.

Cell Host Microbe. 2012 Sep 13;12(3):346-59. doi: 10.1016/j.chom.2012.08.002.


A kinesin-1 binding motif in vaccinia virus that is widespread throughout the human genome.

Dodding MP, Mitter R, Humphries AC, Way M.

EMBO J. 2011 Nov 16;30(22):4523-38. doi: 10.1038/emboj.2011.326.


Coupling viruses to dynein and kinesin-1.

Dodding MP, Way M.

EMBO J. 2011 Aug 31;30(17):3527-39. doi: 10.1038/emboj.2011.283. Review.


F11-mediated inhibition of RhoA signalling enhances the spread of vaccinia virus in vitro and in vivo in an intranasal mouse model of infection.

Cordeiro JV, Guerra S, Arakawa Y, Dodding MP, Esteban M, Way M.

PLoS One. 2009 Dec 30;4(12):e8506. doi: 10.1371/journal.pone.0008506. Erratum in: PLoS One. 2010;5(6). doi: 10.1371/annotation/0c8d44be-4bff-49b3-855a-4cba76160a03.


Nck- and N-WASP-dependent actin-based motility is conserved in divergent vertebrate poxviruses.

Dodding MP, Way M.

Cell Host Microbe. 2009 Dec 17;6(6):536-50. doi: 10.1016/j.chom.2009.10.011.


Vaccinia-induced epidermal growth factor receptor-MEK signalling and the anti-apoptotic protein F1L synergize to suppress cell death during infection.

Postigo A, Martin MC, Dodding MP, Way M.

Cell Microbiol. 2009 Aug;11(8):1208-18. doi: 10.1111/j.1462-5822.2009.01327.x. Epub 2009 Apr 22.


An E2-F12 complex is required for intracellular enveloped virus morphogenesis during vaccinia infection.

Dodding MP, Newsome TP, Collinson LM, Edwards C, Way M.

Cell Microbiol. 2009 May;11(5):808-24. doi: 10.1111/j.1462-5822.2009.01296.x. Epub 2009 Feb 4.


Structure of B-MLV capsid amino-terminal domain reveals key features of viral tropism, gag assembly and core formation.

Mortuza GB, Dodding MP, Goldstone DC, Haire LF, Stoye JP, Taylor IA.

J Mol Biol. 2008 Mar 7;376(5):1493-508. doi: 10.1016/j.jmb.2007.12.043. Epub 2007 Dec 28.


TRIM5 alpha cytoplasmic bodies are highly dynamic structures.

Campbell EM, Dodding MP, Yap MW, Wu X, Gallois-Montbrun S, Malim MH, Stoye JP, Hope TJ.

Mol Biol Cell. 2007 Jun;18(6):2102-11. Epub 2007 Mar 28.


Capsid processing requirements for abrogation of Fv1 and Ref1 restriction.

Dodding MP, Bock M, Yap MW, Stoye JP.

J Virol. 2005 Aug;79(16):10571-7.

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