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Items: 1 to 50 of 190

1.

In vitro Mycobacterial Growth Inhibition in South Korean Adults With Latent TB Infection.

Lee H, Kim J, Kang YA, Kim DR, Sim B, Zelmer A, Fletcher HA, Dockrell HM, Smith SG, Cho SN.

Front Immunol. 2019 Apr 26;10:896. doi: 10.3389/fimmu.2019.00896. eCollection 2019.

2.

Cellular Immune Function in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).

Cliff JM, King EC, Lee JS, Sepúlveda N, Wolf AS, Kingdon C, Bowman E, Dockrell HM, Nacul L, Lacerda E, Riley EM.

Front Immunol. 2019 Apr 16;10:796. doi: 10.3389/fimmu.2019.00796. eCollection 2019.

3.

Evidence of Clinical Pathology Abnormalities in People with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) from an Analytic Cross-Sectional Study.

Nacul L, de Barros B, Kingdon CC, Cliff JM, Clark TG, Mudie K, Dockrell HM, Lacerda EM.

Diagnostics (Basel). 2019 Apr 10;9(2). pii: E41. doi: 10.3390/diagnostics9020041.

4.

Immunometabolic Signatures Predict Risk of Progression to Active Tuberculosis and Disease Outcome.

Duffy FJ, Weiner J 3rd, Hansen S, Tabb DL, Suliman S, Thompson E, Maertzdorf J, Shankar S, Tromp G, Parida S, Dover D, Axthelm MK, Sutherland JS, Dockrell HM, Ottenhoff THM, Scriba TJ, Picker LJ, Walzl G, Kaufmann SHE, Zak DE; GC6-74 Consortium.

Front Immunol. 2019 Mar 22;10:527. doi: 10.3389/fimmu.2019.00527. eCollection 2019.

5.

Diabetes mellitus among pulmonary tuberculosis patients from four TB-endemic countries: the TANDEM study.

Ugarte-Gil C, Alisjahbana B, Ronacher K, Riza AL, Koesoemadinata RC, Malherbe ST, Cioboata R, Llontop JC, Kleynhans L, Lopez S, Santoso P, Marius C, Villaizan K, Ruslami R, Walzl G, Panduru NM, Dockrell HM, Hill PC, Mc Allister S, Pearson F, Moore DAJ, Critchley JA, van Crevel R; TANDEM Consortium.

Clin Infect Dis. 2019 Apr 8. pii: ciz284. doi: 10.1093/cid/ciz284. [Epub ahead of print]

PMID:
30958536
6.

A Feasibility Study for Diagnosis of Latent Tuberculosis Infection Using an IGRA Point-of-Care Platform in South Korea.

Hur YG, Hong JY, Choi DH, Kim A, Park SY, Kwon M, Kang K, Lee JM, Dockrell HM, Lee Y, Joo H, Cho SN.

Yonsei Med J. 2019 Apr;60(4):375-380. doi: 10.3349/ymj.2019.60.4.375.

7.

Point of care HbA1c level for diabetes mellitus management and its accuracy among tuberculosis patients: a study in four countries.

Huangfu P, Laurence YV, Alisjahbana B, Ugarte-Gil C, Riza AL, Walzl G, Ruslami R, Moore DAJ, Ioana M, McAllister S, Ronacher K, Koesoemadinata RC, Grint D, Kerry S, Coronel J, Malherbe ST, Griffiths U, Dockrell HM, Hill PC, van Crevel R, Pearson F, Critchley JA.

Int J Tuberc Lung Dis. 2019 Mar 1;23(3):283-292. doi: 10.5588/ijtld.18.0359.

PMID:
30871659
8.

Metformin Alters Human Host Responses to Mycobacterium tuberculosis in Healthy Subjects.

Lachmandas E, Eckold C, Böhme J, Koeken VACM, Marzuki MB, Blok B, Arts RJW, Chen J, Teng KWW, Ratter J, Smolders EJ, Van den Heuvel C, Stienstra R, Dockrell HM, Newell E, Netea MG, Singhal A, Cliff JM, Van Crevel R.

J Infect Dis. 2019 Jun 5;220(1):139-150. doi: 10.1093/infdis/jiz064.

9.

Optimisation, harmonisation and standardisation of the direct mycobacterial growth inhibition assay using cryopreserved human peripheral blood mononuclear cells.

Tanner R, Smith SG, van Meijgaarden KE, Giannoni F, Wilkie M, Gabriele L, Palma C, Dockrell HM, Ottenhoff THM, McShane H.

J Immunol Methods. 2019 Jun;469:1-10. doi: 10.1016/j.jim.2019.01.006. Epub 2019 Jan 31.

10.

The effects of prednisolone treatment on serological responses and lipid profiles in Ethiopian leprosy patients with Erythema Nodosum Leprosum reactions.

Negera E, Tilahun M, Bobosha K, Lambert SM, Walker SL, Spencer JS, Aseffa A, Dockrell HM, Lockwood DN.

PLoS Negl Trop Dis. 2018 Dec 28;12(12):e0007035. doi: 10.1371/journal.pntd.0007035. eCollection 2018 Dec.

11.

Metabolite changes in blood predict the onset of tuberculosis.

Weiner J 3rd, Maertzdorf J, Sutherland JS, Duffy FJ, Thompson E, Suliman S, McEwen G, Thiel B, Parida SK, Zyla J, Hanekom WA, Mohney RP, Boom WH, Mayanja-Kizza H, Howe R, Dockrell HM, Ottenhoff THM, Scriba TJ, Zak DE, Walzl G, Kaufmann SHE; GC6-74 consortium.

Nat Commun. 2018 Dec 6;9(1):5208. doi: 10.1038/s41467-018-07635-7.

12.

Meeting report: 5th Global Forum on TB Vaccines, 20-23 February 2018, New Delhi India.

Atmakuri K, Penn-Nicholson A, Tanner R, Dockrell HM.

Tuberculosis (Edinb). 2018 Dec;113:55-64. doi: 10.1016/j.tube.2018.08.013. Epub 2018 Aug 24.

13.

Accuracy of diabetes screening methods used for people with tuberculosis, Indonesia, Peru, Romania, South Africa.

Grint D, Alisjhabana B, Ugarte-Gil C, Riza AL, Walzl G, Pearson F, Ruslami R, Moore DAJ, Ioana M, McAllister S, Ronacher K, Koeseomadinata RC, Kerry-Barnard SR, Coronel J, Malherbe ST, Dockrell HM, Hill PC, Van Crevel R, Critchley JA; TANDEM consortium.

Bull World Health Organ. 2018 Nov 1;96(11):738-749. doi: 10.2471/BLT.17.206227. Epub 2018 Aug 27.

14.

Cross-laboratory evaluation of multiplex bead assays including independent common reference standards for immunological monitoring of observational and interventional human studies.

van Meijgaarden KE, Khatri B, Smith SG, Drittij AMFH, de Paus RA, Goeman JJ, Ho MM, Dockrell HM, McShane H, Joosten SA, Ottenhoff THM.

PLoS One. 2018 Sep 4;13(9):e0201205. doi: 10.1371/journal.pone.0201205. eCollection 2018.

15.

Differential DNA methylation of potassium channel KCa3.1 and immune signalling pathways is associated with infant immune responses following BCG vaccination.

Hasso-Agopsowicz M, Scriba TJ, Hanekom WA, Dockrell HM, Smith SG.

Sci Rep. 2018 Aug 30;8(1):13086. doi: 10.1038/s41598-018-31537-9.

16.

Disease characteristics and treatment of patients with diabetes mellitus attending government health services in Indonesia, Peru, Romania and South Africa.

Soetedjo NNM, McAllister SM, Ugarte-Gil C, Firanescu AG, Ronacher K, Alisjahbana B, Costache AL, Zubiate C, Malherbe ST, Koesoemadinata RC, Laurence YV, Pearson F, Kerry-Barnard S, Ruslami R, Moore DAJ, Ioana M, Kleynhans L, Permana H, Hill PC, Mota M, Walzl G, Dockrell HM, Critchley JA, van Crevel R; TANDEM Consortium.

Trop Med Int Health. 2018 Oct;23(10):1118-1128. doi: 10.1111/tmi.13137. Epub 2018 Sep 10.

PMID:
30106222
17.

Addressing diversity in tuberculosis using multidimensional approaches.

Lerm M, Dockrell HM.

J Intern Med. 2018 May 27. doi: 10.1111/joim.12776. [Epub ahead of print]

PMID:
29804295
18.

A Serum Circulating miRNA Signature for Short-Term Risk of Progression to Active Tuberculosis Among Household Contacts.

Duffy FJ, Thompson E, Downing K, Suliman S, Mayanja-Kizza H, Boom WH, Thiel B, Weiner Iii J, Kaufmann SHE, Dover D, Tabb DL, Dockrell HM, Ottenhoff THM, Tromp G, Scriba TJ, Zak DE, Walzl G; GC6-74 Consortium.

Front Immunol. 2018 Apr 13;9:661. doi: 10.3389/fimmu.2018.00661. eCollection 2018.

19.

Post-immunization leucocytosis and its implications for the management of febrile infants.

Prentice S, Kamushaaga Z, Nash SB, Elliott AM, Dockrell HM, Cose S.

Vaccine. 2018 May 11;36(20):2870-2875. doi: 10.1016/j.vaccine.2018.03.026. Epub 2018 Apr 11.

20.

Complement C1q expression in Erythema nodosum leprosum.

Negera E, Walker SL, Lema T, Aseffa A, Lockwood DN, Dockrell HM.

PLoS Negl Trop Dis. 2018 Mar 2;12(3):e0006321. doi: 10.1371/journal.pntd.0006321. eCollection 2018 Mar.

21.

The Effects of Prednisolone Treatment on Cytokine Expression in Patients with Erythema Nodosum Leprosum Reactions.

Negera E, Walker SL, Bobosha K, Bekele Y, Endale B, Tarekegn A, Abebe M, Aseffa A, Dockrell HM, Lockwood DN.

Front Immunol. 2018 Feb 9;9:189. doi: 10.3389/fimmu.2018.00189. eCollection 2018.

22.

Africa-wide evaluation of host biomarkers in QuantiFERON supernatants for the diagnosis of pulmonary tuberculosis.

Chegou NN, Sutherland JS, Namuganga AR, Corstjens PL, Geluk A, Gebremichael G, Mendy J, Malherbe S, Stanley K, van der Spuy GD, Kriel M, Loxton AG, Kriel B, Simukonda F, Bekele Y, Sheehama JA, Nelongo J, van der Vyver M, Gebrexabher A, Hailu H, Esterhuyse MM, Rosenkrands I, Aagard C, Kidd M, Kassa D, Mihret A, Howe R, Cliff JM, Crampin AC, Mayanja-Kizza H, Kaufmann SHE, Dockrell HM, Ottenhoff THM, Walzl G; AE-TBC consortium.

Sci Rep. 2018 Feb 8;8(1):2675. doi: 10.1038/s41598-018-20855-7.

23.

Tuberculosis vaccines: Opportunities and challenges.

Zhu B, Dockrell HM, Ottenhoff THM, Evans TG, Zhang Y.

Respirology. 2018 Apr;23(4):359-368. doi: 10.1111/resp.13245. Epub 2018 Jan 17. Review.

24.

Increased activated memory B-cells in the peripheral blood of patients with erythema nodosum leprosum reactions.

Negera E, Walker SL, Bekele Y, Dockrell HM, Lockwood DN.

PLoS Negl Trop Dis. 2017 Dec 18;11(12):e0006121. doi: 10.1371/journal.pntd.0006121. eCollection 2017 Dec.

25.

TBVAC2020: Advancing Tuberculosis Vaccines from Discovery to Clinical Development.

Kaufmann SHE, Dockrell HM, Drager N, Ho MM, McShane H, Neyrolles O, Ottenhoff THM, Patel B, Roordink D, Spertini F, Stenger S, Thole J, Verreck FAW, Williams A; TBVAC2020 Consortium.

Front Immunol. 2017 Oct 4;8:1203. doi: 10.3389/fimmu.2017.01203. eCollection 2017. Review.

26.

Clinico-pathological features of erythema nodosum leprosum: A case-control study at ALERT hospital, Ethiopia.

Negera E, Walker SL, Girma S, Doni SN, Tsegaye D, Lambert SM, Idriss MH, Tsegay Y, Dockrell HM, Aseffa A, Lockwood DN.

PLoS Negl Trop Dis. 2017 Oct 13;11(10):e0006011. doi: 10.1371/journal.pntd.0006011. eCollection 2017 Oct.

27.

Assay optimisation and technology transfer for multi-site immuno-monitoring in vaccine trials.

Smith SG, Harris SA, Satti I, Bryan D, Walker KB, Dockrell HM, McShane H, Ho MM.

PLoS One. 2017 Oct 11;12(10):e0184391. doi: 10.1371/journal.pone.0184391. eCollection 2017.

28.

T-cell regulation in Erythema Nodosum Leprosum.

Negera E, Walker SL, Bobosha K, Howe R, Aseffa A, Dockrell HM, Lockwood DN.

PLoS Negl Trop Dis. 2017 Oct 9;11(10):e0006001. doi: 10.1371/journal.pntd.0006001. eCollection 2017 Oct.

29.

New Insight into the Pathogenesis of Erythema Nodosum Leprosum: The Role of Activated Memory T-Cells.

Negera E, Bobosha K, Walker SL, Endale B, Howe R, Aseffa A, Dockrell HM, Lockwood DN.

Front Immunol. 2017 Sep 15;8:1149. doi: 10.3389/fimmu.2017.01149. eCollection 2017.

30.

What Have We Learnt about BCG Vaccination in the Last 20 Years?

Dockrell HM, Smith SG.

Front Immunol. 2017 Sep 13;8:1134. doi: 10.3389/fimmu.2017.01134. eCollection 2017. Review.

31.

The UK ME/CFS Biobank for biomedical research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Multiple Sclerosis.

Lacerda EM, Bowman EW, Cliff JM, Kingdon CC, King EC, Lee JS, Clark TG, Dockrell HM, Riley EM, Curran H, Nacul L.

Open J Bioresour. 2017;4. pii: 4. doi: 10.5334/ojb.28. Epub 2017 Feb 20.

32.
33.

Working together toward vaccines and biomarkers in the real world.

Dockrell HM.

Hum Vaccin Immunother. 2017 Jul 3;13(7):1492-1494. doi: 10.1080/21645515.2017.1322443. Epub 2017 Jun 2. No abstract available.

34.

Association of slow recovery of Mycobacterium africanum-infected patients posttreatment with high content of Persister-Like bacilli in pretreatment sputum.

Tientcheu LD, Bell A, Secka O, Ayorinde A, Otu J, Garton NJ, Sutherland JS, Ota MO, Antonio M, Dockrell HM, Kampmann B, Barer MR.

Int J Mycobacteriol. 2016 Dec;5 Suppl 1:S99-S100. doi: 10.1016/j.ijmyco.2016.09.033. Epub 2016 Nov 11.

35.

Maternal BCG scar is associated with increased infant proinflammatory immune responses.

Mawa PA, Webb EL, Filali-Mouhim A, Nkurunungi G, Sekaly RP, Lule SA, Prentice S, Nash S, Dockrell HM, Elliott AM, Cose S.

Vaccine. 2017 Jan 5;35(2):273-282. doi: 10.1016/j.vaccine.2016.11.079. Epub 2016 Nov 30.

36.

Polyfunctional CD4 T-cells correlate with in vitro mycobacterial growth inhibition following Mycobacterium bovis BCG-vaccination of infants.

Smith SG, Zelmer A, Blitz R, Fletcher HA, Dockrell HM.

Vaccine. 2016 Oct 17;34(44):5298-5305. doi: 10.1016/j.vaccine.2016.09.002. Epub 2016 Sep 9.

37.

Evaluation of cytokine responses against novel Mtb antigens as diagnostic markers for TB disease.

Awoniyi DO, Teuchert A, Sutherland JS, Mayanja-Kizza H, Howe R, Mihret A, Loxton AG, Sheehama J, Kassa D, Crampin AC, Dockrell HM, Kidd M, Rosenkrands I, Geluk A, Ottenhoff TH, Corstjens PL, Chegou NN, Walzl G; AE-TBC Consortium.

J Infect. 2016 Sep;73(3):219-30. doi: 10.1016/j.jinf.2016.04.036. Epub 2016 Jun 14.

38.

Human biomarkers: can they help us to develop a new tuberculosis vaccine?

Fletcher HA, Dockrell HM.

Future Microbiol. 2016 Jun;11:781-7. doi: 10.2217/fmb.16.15. Epub 2016 May 20. Review.

39.

Host Immune Responses Differ between M. africanum- and M. tuberculosis-Infected Patients following Standard Anti-tuberculosis Treatment.

Tientcheu LD, Haks MC, Agbla SC, Sutherland JS, Adetifa IM, Donkor S, Quinten E, Daramy M, Antonio M, Kampmann B, Ottenhoff TH, Dockrell HM, Ota MO.

PLoS Negl Trop Dis. 2016 May 18;10(5):e0004701. doi: 10.1371/journal.pntd.0004701. eCollection 2016 May.

40.

Mapping of Mycobacterium tuberculosis Complex Genetic Diversity Profiles in Tanzania and Other African Countries.

Mbugi EV, Katale BZ, Streicher EM, Keyyu JD, Kendall SL, Dockrell HM, Michel AL, Rweyemamu MM, Warren RM, Matee MI, van Helden PD, Couvin D, Rastogi N.

PLoS One. 2016 May 5;11(5):e0154571. doi: 10.1371/journal.pone.0154571. eCollection 2016.

41.

Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and symptoms suggestive of TB.

Chegou NN, Sutherland JS, Malherbe S, Crampin AC, Corstjens PL, Geluk A, Mayanja-Kizza H, Loxton AG, van der Spuy G, Stanley K, Kotzé LA, van der Vyver M, Rosenkrands I, Kidd M, van Helden PD, Dockrell HM, Ottenhoff TH, Kaufmann SH, Walzl G; AE-TBC consortium.

Thorax. 2016 Sep;71(9):785-94. doi: 10.1136/thoraxjnl-2015-207999. Epub 2016 May 4.

42.

A blood RNA signature for tuberculosis disease risk: a prospective cohort study.

Zak DE, Penn-Nicholson A, Scriba TJ, Thompson E, Suliman S, Amon LM, Mahomed H, Erasmus M, Whatney W, Hussey GD, Abrahams D, Kafaar F, Hawkridge T, Verver S, Hughes EJ, Ota M, Sutherland J, Howe R, Dockrell HM, Boom WH, Thiel B, Ottenhoff THM, Mayanja-Kizza H, Crampin AC, Downing K, Hatherill M, Valvo J, Shankar S, Parida SK, Kaufmann SHE, Walzl G, Aderem A, Hanekom WA; ACS and GC6-74 cohort study groups.

Lancet. 2016 Jun 4;387(10035):2312-2322. doi: 10.1016/S0140-6736(15)01316-1. Epub 2016 Mar 24.

43.

Towards new TB vaccines: What are the challenges?

Dockrell HM.

Pathog Dis. 2016 Jun;74(4):ftw016. Review.

PMID:
26960944
44.

The Use of Interferon Gamma Inducible Protein 10 as a Potential Biomarker in the Diagnosis of Latent Tuberculosis Infection in Uganda.

Biraro IA, Kimuda S, Egesa M, Cose S, Webb EL, Joloba M, Smith SG, Elliott AM, Dockrell HM, Katamba A.

PLoS One. 2016 Jan 15;11(1):e0146098. doi: 10.1371/journal.pone.0146098. eCollection 2016.

45.

Mycobacterium tuberculosis-specific CD4+ T-cell response is increased, and Treg cells decreased, in anthelmintic-treated patients with latent TB.

Toulza F, Tsang L, Ottenhoff TH, Brown M, Dockrell HM.

Eur J Immunol. 2016 Mar;46(3):752-61. doi: 10.1002/eji.201545843. Epub 2016 Jan 11.

46.

Isolation and Potential for Transmission of Mycobacterium bovis at Human-livestock-wildlife Interface of the Serengeti Ecosystem, Northern Tanzania.

Katale BZ, Mbugi EV, Siame KK, Keyyu JD, Kendall S, Kazwala RR, Dockrell HM, Fyumagwa RD, Michel AL, Rweyemamu M, Streicher EM, Warren RM, van Helden P, Matee MI.

Transbound Emerg Dis. 2017 Jun;64(3):815-825. doi: 10.1111/tbed.12445. Epub 2015 Nov 13.

47.

Effect of isoniazid preventive therapy on immune responses to mycobacterium tuberculosis: an open label randomised, controlled, exploratory study.

Biraro IA, Egesa M, Kimuda S, Smith SG, Toulza F, Levin J, Joloba M, Katamba A, Cose S, Dockrell HM, Elliott AM.

BMC Infect Dis. 2015 Oct 22;15:438. doi: 10.1186/s12879-015-1201-8.

48.

Intracellular Cytokine Staining and Flow Cytometry: Considerations for Application in Clinical Trials of Novel Tuberculosis Vaccines.

Smith SG, Smits K, Joosten SA, van Meijgaarden KE, Satti I, Fletcher HA, Caccamo N, Dieli F, Mascart F, McShane H, Dockrell HM, Ottenhoff TH; TBVI TB Biomarker Working Group.

PLoS One. 2015 Sep 14;10(9):e0138042. doi: 10.1371/journal.pone.0138042. eCollection 2015.

49.

PD-1, PD-L1 and PD-L2 Gene Expression on T-Cells and Natural Killer Cells Declines in Conjunction with a Reduction in PD-1 Protein during the Intensive Phase of Tuberculosis Treatment.

Hassan SS, Akram M, King EC, Dockrell HM, Cliff JM.

PLoS One. 2015 Sep 11;10(9):e0137646. doi: 10.1371/journal.pone.0137646. eCollection 2015.

50.

Excessive Cytolytic Responses Predict Tuberculosis Relapse After Apparently Successful Treatment.

Cliff JM, Cho JE, Lee JS, Ronacher K, King EC, van Helden P, Walzl G, Dockrell HM.

J Infect Dis. 2016 Feb 1;213(3):485-95. doi: 10.1093/infdis/jiv447. Epub 2015 Sep 7.

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