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Items: 1 to 50 of 69

1.

Cells under pressure - the relationship between hydrostatic pressure and mesenchymal stem cell chondrogenesis.

Pattappa G, Zellner J, Johnstone B, Docheva D, Angele P.

Eur Cell Mater. 2019 May 6;37:360-381. doi: 10.22203/eCM.v037a22.

PMID:
31056740
2.

Tenomodulin regulates matrix remodeling of mouse tendon stem/progenitor cells in an ex vivo collagen I gel model.

Yin H, Caceres MD, Yan Z, Schieker M, Nerlich M, Docheva D.

Biochem Biophys Res Commun. 2019 May 14;512(4):691-697. doi: 10.1016/j.bbrc.2019.03.063. Epub 2019 Mar 25.

3.

The Importance of Physioxia in Mesenchymal Stem Cell Chondrogenesis and the Mechanisms Controlling Its Response.

Pattappa G, Johnstone B, Zellner J, Docheva D, Angele P.

Int J Mol Sci. 2019 Jan 23;20(3). pii: E484. doi: 10.3390/ijms20030484. Review.

4.

Age related changes in cell stiffness of tendon stem/progenitor cells and a rejuvenating effect of ROCK-inhibition.

Kiderlen S, Polzer C, Rädler JO, Docheva D, Clausen-Schaumann H, Sudhop S.

Biochem Biophys Res Commun. 2019 Feb 12;509(3):839-844. doi: 10.1016/j.bbrc.2019.01.027. Epub 2019 Jan 11.

5.

In Vitro Weight-Loaded Cell Models for Understanding Mechanodependent Molecular Pathways Involved in Orthodontic Tooth Movement: A Systematic Review.

Janjic M, Docheva D, Trickovic Janjic O, Wichelhaus A, Baumert U.

Stem Cells Int. 2018 Jul 31;2018:3208285. doi: 10.1155/2018/3208285. eCollection 2018. Review.

6.

In Vitro Comparison of 2D-Cell Culture and 3D-Cell Sheets of Scleraxis-Programmed Bone Marrow Derived Mesenchymal Stem Cells to Primary Tendon Stem/Progenitor Cells for Tendon Repair.

Hsieh CF, Yan Z, Schumann RG, Milz S, Pfeifer CG, Schieker M, Docheva D.

Int J Mol Sci. 2018 Aug 2;19(8). pii: E2272. doi: 10.3390/ijms19082272.

7.

Understanding Tendons: Lessons from Transgenic Mouse Models.

Delgado Caceres M, Pfeifer CG, Docheva D.

Stem Cells Dev. 2018 Sep 1;27(17):1161-1174. doi: 10.1089/scd.2018.0121. Epub 2018 Aug 10.

8.

Functionalized thermosensitive hydrogel combined with tendon stem/progenitor cells as injectable cell delivery carrier for tendon tissue engineering.

Yin H, Yan Z, Bauer RJ, Peng J, Schieker M, Nerlich M, Docheva D.

Biomed Mater. 2018 Mar 16;13(3):034107. doi: 10.1088/1748-605X/aaadd1.

PMID:
29417934
9.

Boosting tendon repair: interplay of cells, growth factors and scaffold-free and gel-based carriers.

Yan Z, Yin H, Nerlich M, Pfeifer CG, Docheva D.

J Exp Orthop. 2018 Jan 5;5(1):1. doi: 10.1186/s40634-017-0117-1. Review.

10.

Rescue plan for Achilles: Therapeutics steering the fate and functions of stem cells in tendon wound healing.

Schneider M, Angele P, Järvinen TAH, Docheva D.

Adv Drug Deliv Rev. 2018 Apr;129:352-375. doi: 10.1016/j.addr.2017.12.016. Epub 2017 Dec 24. Review.

11.

Achilles tendon elastic properties remain decreased in long term after rupture.

Frankewycz B, Penz A, Weber J, da Silva NP, Freimoser F, Bell R, Nerlich M, Jung EM, Docheva D, Pfeifer CG.

Knee Surg Sports Traumatol Arthrosc. 2018 Jul;26(7):2080-2087. doi: 10.1007/s00167-017-4791-4. Epub 2017 Nov 16.

PMID:
29147741
12.

Mysteries Behind the Cellular Content of Tendon Tissues.

Schneider M, Docheva D.

J Am Acad Orthop Surg. 2017 Dec;25(12):e289-e290. doi: 10.5435/JAAOS-D-17-00520. No abstract available.

PMID:
29076923
13.

Tenomodulin is essential for prevention of adipocyte accumulation and fibrovascular scar formation during early tendon healing.

Lin D, Alberton P, Caceres MD, Volkmer E, Schieker M, Docheva D.

Cell Death Dis. 2017 Oct 12;8(10):e3116. doi: 10.1038/cddis.2017.510.

14.

Tendon injuries: Basic science and new repair proposals.

Wu F, Nerlich M, Docheva D.

EFORT Open Rev. 2017 Jul 27;2(7):332-342. doi: 10.1302/2058-5241.2.160075. eCollection 2017 Jul. Review.

15.

A cell culture technique for human epiretinal membranes to describe cell behavior and membrane contraction in vitro.

Wertheimer C, Eibl-Lindner KH, Compera D, Kueres A, Wolf A, Docheva D, Priglinger SG, Priglinger C, Schumann RG.

Graefes Arch Clin Exp Ophthalmol. 2017 Nov;255(11):2147-2155. doi: 10.1007/s00417-017-3767-x. Epub 2017 Aug 7.

PMID:
28782074
16.

Wnt/β-catenin signaling suppresses expressions of Scx, Mkx, and Tnmd in tendon-derived cells.

Kishimoto Y, Ohkawara B, Sakai T, Ito M, Masuda A, Ishiguro N, Shukunami C, Docheva D, Ohno K.

PLoS One. 2017 Jul 27;12(7):e0182051. doi: 10.1371/journal.pone.0182051. eCollection 2017.

17.

The effect of estrogen on tendon and ligament metabolism and function.

Leblanc DR, Schneider M, Angele P, Vollmer G, Docheva D.

J Steroid Biochem Mol Biol. 2017 Sep;172:106-116. doi: 10.1016/j.jsbmb.2017.06.008. Epub 2017 Jun 16. Review.

18.

Tenomodulin is Required for Tendon Endurance Running and Collagen I Fibril Adaptation to Mechanical Load.

Dex S, Alberton P, Willkomm L, Söllradl T, Bago S, Milz S, Shakibaei M, Ignatius A, Bloch W, Clausen-Schaumann H, Shukunami C, Schieker M, Docheva D.

EBioMedicine. 2017 Jun;20:240-254. doi: 10.1016/j.ebiom.2017.05.003. Epub 2017 May 5.

19.

Prolotherapy Induces an Inflammatory Response in Human Tenocytes In Vitro.

Ekwueme EC, Mohiuddin M, Yarborough JA, Brolinson PG, Docheva D, Fernandes HAM, Freeman JW.

Clin Orthop Relat Res. 2017 Aug;475(8):2117-2127. doi: 10.1007/s11999-017-5370-1. Epub 2017 Apr 27.

20.

Periodontal ligament cells as alternative source for cell-based therapy of tendon injuries: in vivo study of full-size Achilles tendon defect in a rat model.

Hsieh CF, Alberton P, Loffredo-Verde E, Volkmer E, Pietschmann M, Müller PE, Schieker M, Docheva D.

Eur Cell Mater. 2016 Oct 20;32:228-240.

PMID:
27763655
21.

Tenogenic modulating insider factor: Systematic assessment on the functions of tenomodulin gene.

Dex S, Lin D, Shukunami C, Docheva D.

Gene. 2016 Aug 1;587(1):1-17. doi: 10.1016/j.gene.2016.04.051. Epub 2016 Apr 26. Review.

22.

Scaffold-free Scleraxis-programmed tendon progenitors aid in significantly enhanced repair of full-size Achilles tendon rupture.

Hsieh CF, Alberton P, Loffredo-Verde E, Volkmer E, Pietschmann M, Müller P, Schieker M, Docheva D.

Nanomedicine (Lond). 2016 May;11(9):1153-67. doi: 10.2217/nnm.16.34. Epub 2016 Apr 13.

23.
24.

Decoding Cytoskeleton-Anchored and Non-Anchored Receptors from Single-Cell Adhesion Force Data.

Sariisik E, Popov C, Müller JP, Docheva D, Clausen-Schaumann H, Benoit M.

Biophys J. 2015 Oct 6;109(7):1330-3. doi: 10.1016/j.bpj.2015.07.048.

25.

Mechanical stimulation of human tendon stem/progenitor cells results in upregulation of matrix proteins, integrins and MMPs, and activation of p38 and ERK1/2 kinases.

Popov C, Burggraf M, Kreja L, Ignatius A, Schieker M, Docheva D.

BMC Mol Biol. 2015 Mar 13;16:6. doi: 10.1186/s12867-015-0036-6.

26.

Biologics for tendon repair.

Docheva D, Müller SA, Majewski M, Evans CH.

Adv Drug Deliv Rev. 2015 Apr;84:222-39. doi: 10.1016/j.addr.2014.11.015. Epub 2014 Nov 21. Review.

27.

Loss of tenomodulin results in reduced self-renewal and augmented senescence of tendon stem/progenitor cells.

Alberton P, Dex S, Popov C, Shukunami C, Schieker M, Docheva D.

Stem Cells Dev. 2015 Mar 1;24(5):597-609. doi: 10.1089/scd.2014.0314. Epub 2014 Dec 10.

28.

Influence of osteogenic stimulation and VEGF treatment on in vivo bone formation in hMSC-seeded cancellous bone scaffolds.

Lenze U, Pohlig F, Seitz S, Ern C, Milz S, Docheva D, Schieker M.

BMC Musculoskelet Disord. 2014 Oct 16;15:350. doi: 10.1186/1471-2474-15-350.

29.

Mesenchymal stem cells from osteoporotic patients reveal reduced migration and invasion upon stimulation with BMP-2 or BMP-7.

Haasters F, Docheva D, Gassner C, Popov C, Böcker W, Mutschler W, Schieker M, Prall WC.

Biochem Biophys Res Commun. 2014 Sep 12;452(1):118-23. doi: 10.1016/j.bbrc.2014.08.055. Epub 2014 Aug 21.

30.

Integrin signaling in skeletal development and function.

Docheva D, Popov C, Alberton P, Aszodi A.

Birth Defects Res C Embryo Today. 2014 Mar;102(1):13-36. doi: 10.1002/bdrc.21059. Review.

PMID:
24677721
31.

EGFR-blockade with erlotinib reduces EGF and TGF-β2 expression and the actin-cytoskeleton which influences different aspects of cellular migration in lens epithelial cells.

Wertheimer C, Liegl R, Kernt M, Docheva D, Kampik A, Eibl-Lindner KH.

Curr Eye Res. 2014 Oct;39(10):1000-12. doi: 10.3109/02713683.2014.888453. Epub 2014 Mar 3.

PMID:
24588338
32.

MicroRNA-23a mediates post-transcriptional regulation of CXCL12 in bone marrow stromal cells.

Arabanian LS, Fierro FA, Stölzel F, Heder C, Poitz DM, Strasser RH, Wobus M, Borhäuser M, Ferrer RA, Platzbecker U, Schieker M, Docheva D, Ehninger G, Illmer T.

Haematologica. 2014 Jun;99(6):997-1005. doi: 10.3324/haematol.2013.097675. Epub 2014 Feb 28.

33.

Arthritic periosteal tissue from joint replacement surgery: a novel, autologous source of stem cells.

Chang H, Docheva D, Knothe UR, Knothe Tate ML.

Stem Cells Transl Med. 2014 Mar;3(3):308-17. doi: 10.5966/sctm.2013-0056. Epub 2014 Jan 29.

34.

Assessment of essential characteristics of two different scaffolds for tendon in situ regeneration.

Wagenhäuser MU, Pietschmann MF, Docheva D, Gülecyüz MF, Jansson V, Müller PE.

Knee Surg Sports Traumatol Arthrosc. 2015 Apr;23(4):1239-46. doi: 10.1007/s00167-013-2820-5. Epub 2014 Jan 4.

PMID:
24389992
35.

Attenuation of human lens epithelial cell spreading, migration and contraction via downregulation of the PI3K/Akt pathway.

Liegl R, Wertheimer C, Kernt M, Docheva D, Kampik A, Eibl-Lindner KH.

Graefes Arch Clin Exp Ophthalmol. 2014 Feb;252(2):285-92. doi: 10.1007/s00417-013-2524-z. Epub 2013 Nov 22.

PMID:
24263529
36.

MiR-134-mediated β1 integrin expression and function in mesenchymal stem cells.

Poitz DM, Stölzel F, Arabanian L, Friedrichs J, Docheva D, Schieker M, Fierro FA, Platzbecker U, Ordemann R, Werner C, Bornhäuser M, Strasser RH, Ehninger G, Illmer T.

Biochim Biophys Acta. 2013 Dec;1833(12):3396-3404. doi: 10.1016/j.bbamcr.2013.10.003. Epub 2013 Oct 15.

37.

Uncovering the cellular and molecular changes in tendon stem/progenitor cells attributed to tendon aging and degeneration.

Kohler J, Popov C, Klotz B, Alberton P, Prall WC, Haasters F, Müller-Deubert S, Ebert R, Klein-Hitpass L, Jakob F, Schieker M, Docheva D.

Aging Cell. 2013 Dec;12(6):988-99. doi: 10.1111/acel.12124. Epub 2013 Jul 22.

38.

Overexpression of dnIKK in mesenchymal stem cells leads to increased migration and decreased invasion upon TNFα stimulation.

Haasters F, Prall WC, Westphal I, Böcker W, Padula D, Mutschler W, Docheva D, Schieker M.

Biochem Biophys Res Commun. 2013 Jun 28;436(2):265-70. doi: 10.1016/j.bbrc.2013.05.091. Epub 2013 Jun 4.

PMID:
23743204
39.

Tenomodulin expression in the periodontal ligament enhances cellular adhesion.

Komiyama Y, Ohba S, Shimohata N, Nakajima K, Hojo H, Yano F, Takato T, Docheva D, Shukunami C, Hiraki Y, Chung UI.

PLoS One. 2013 Apr 10;8(4):e60203. doi: 10.1371/journal.pone.0060203. Print 2013.

40.

Probing the interaction forces of prostate cancer cells with collagen I and bone marrow derived stem cells on the single cell level.

Sariisik E, Docheva D, Padula D, Popov C, Opfer J, Schieker M, Clausen-Schaumann H, Benoit M.

PLoS One. 2013;8(3):e57706. doi: 10.1371/journal.pone.0057706. Epub 2013 Mar 5. Erratum in: PLoS One. 2013.8(10). doi:10.1371/annotation/d7f2081e-8756-4253-a066-7fb084cd0759.

41.

EGF receptor inhibitor erlotinib as a potential pharmacological prophylaxis for posterior capsule opacification.

Wertheimer C, Liegl R, Kernt M, Mayer W, Docheva D, Kampik A, Eibl-Lindner KH.

Graefes Arch Clin Exp Ophthalmol. 2013 Jun;251(6):1529-40. doi: 10.1007/s00417-013-2257-z. Epub 2013 Jan 18.

PMID:
23329402
42.

Solid-supported lipid bilayers to drive stem cell fate and tissue architecture using periosteum derived progenitor cells.

Evans SF, Docheva D, Bernecker A, Colnot C, Richter RP, Knothe Tate ML.

Biomaterials. 2013 Mar;34(8):1878-87. doi: 10.1016/j.biomaterials.2012.09.024. Epub 2012 Dec 11.

PMID:
23237517
43.

Comparison of tenocytes and mesenchymal stem cells seeded on biodegradable scaffolds in a full-size tendon defect model.

Pietschmann MF, Frankewycz B, Schmitz P, Docheva D, Sievers B, Jansson V, Schieker M, Müller PE.

J Mater Sci Mater Med. 2013 Jan;24(1):211-20. doi: 10.1007/s10856-012-4791-3. Epub 2012 Oct 23.

PMID:
23090834
44.

Multiscale computational and experimental approaches to elucidate bone and ligament mechanobiology using the ulna-radius-interosseous membrane construct as a model system.

Knothe Tate ML, Tami AE, Netrebko P, Milz S, Docheva D.

Technol Health Care. 2012;20(5):363-78. doi: 10.3233/THC-2012-0686. Review.

PMID:
23079942
45.

Collagen type I and decorin expression in tenocytes depend on the cell isolation method.

Wagenhäuser MU, Pietschmann MF, Sievers B, Docheva D, Schieker M, Jansson V, Müller PE.

BMC Musculoskelet Disord. 2012 Aug 8;13:140. doi: 10.1186/1471-2474-13-140.

46.

Increased stemness and migration of human mesenchymal stem cells in hypoxia is associated with altered integrin expression.

Saller MM, Prall WC, Docheva D, Schönitzer V, Popov T, Anz D, Clausen-Schaumann H, Mutschler W, Volkmer E, Schieker M, Polzer H.

Biochem Biophys Res Commun. 2012 Jun 29;423(2):379-85. doi: 10.1016/j.bbrc.2012.05.134. Epub 2012 Jun 1.

PMID:
22664105
47.

[Alterations of cell phenotype in Dupuytren's disease--an in vitro analysis].

Docheva D, Vaerst B, Deiler S, Giunta RE, Schieker M, Volkmer E.

Handchir Mikrochir Plast Chir. 2012 Apr;44(2):59-66. doi: 10.1055/s-0032-1309025. Epub 2012 Apr 11. German.

PMID:
22495955
48.

In situ guided tissue regeneration in musculoskeletal diseases and aging : Implementing pathology into tailored tissue engineering strategies.

Jakob F, Ebert R, Rudert M, Nöth U, Walles H, Docheva D, Schieker M, Meinel L, Groll J.

Cell Tissue Res. 2012 Mar;347(3):725-35. doi: 10.1007/s00441-011-1237-z. Epub 2011 Oct 20. Review.

49.

Conversion of human bone marrow-derived mesenchymal stem cells into tendon progenitor cells by ectopic expression of scleraxis.

Alberton P, Popov C, Prägert M, Kohler J, Shukunami C, Schieker M, Docheva D.

Stem Cells Dev. 2012 Apr 10;21(6):846-58. doi: 10.1089/scd.2011.0150. Epub 2011 Oct 11.

50.

Integrins α2β1 and α11β1 regulate the survival of mesenchymal stem cells on collagen I.

Popov C, Radic T, Haasters F, Prall WC, Aszodi A, Gullberg D, Schieker M, Docheva D.

Cell Death Dis. 2011 Jul 28;2:e186. doi: 10.1038/cddis.2011.71.

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