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Ethnic and socioeconomic associations with multiple sclerosis risk.

Dobson R, Jitlal M, Marshall CR, Noyce AJ, Robson J, Cuzick J, Giovannoni G.

Ann Neurol. 2020 Jan 23. doi: 10.1002/ana.25688. [Epub ahead of print]


Structure-function analyses of alkylhydroperoxidase D from Streptococcus pneumoniae reveal an unusual three-cysteine active site architecture.

Meng Y, Sheen CR, Magon NJ, Hampton MB, Dobson RCJ.

J Biol Chem. 2020 Jan 23. pii: jbc.RA119.012226. doi: 10.1074/jbc.RA119.012226. [Epub ahead of print]


A simple method to deliver increased inspired oxygen to continuous positive airway pressure machines in the perioperative period: A benchtop study to determine feasibility.

Dobson RE, Gardner AI, Foley MJ.

Anaesth Intensive Care. 2020 Jan 20:310057X19894344. doi: 10.1177/0310057X19894344. [Epub ahead of print] No abstract available.


Comparing the Conformational Stability of Pyruvate Kinase in the Gas Phase and in Solution.

Nouchikian L, Lento C, Donovan K, Dobson R, Wilson DJ.

J Am Soc Mass Spectrom. 2020 Jan 17. [Epub ahead of print]


On classifying sepsis heterogeneity in the ICU: insight using machine learning.

Ibrahim ZM, Wu H, Hamoud A, Stappen L, Dobson RJB, Agarossi A.

J Am Med Inform Assoc. 2020 Jan 17. pii: ocz211. doi: 10.1093/jamia/ocz211. [Epub ahead of print]


The basis for non-canonical ROK family function in the N-acetylmannosamine kinase from the pathogen Staphylococcus aureus.

Coombes D, Davies JS, Newton-Vesty MC, Horne CR, Setty TG, Subramanian R, Moir JWB, Friemann R, Panjikar S, Griffin MDW, North RA, Dobson RCJ.

J Biol Chem. 2020 Jan 15. pii: jbc.RA119.010526. doi: 10.1074/jbc.RA119.010526. [Epub ahead of print]


BMI and low vitamin D are causal factors for multiple sclerosis: A Mendelian Randomization study.

Jacobs BM, Noyce AJ, Giovannoni G, Dobson R.

Neurol Neuroimmunol Neuroinflamm. 2020 Jan 14;7(2). pii: e662. doi: 10.1212/NXI.0000000000000662. Print 2020 Mar.


A Web-Based Alcohol Risk Communication Tool: Development and Pretesting Study.

Kool B, Dobson R, Sharpe S, Humphrey G, Whittaker R, Ameratunga S.

JMIR Form Res. 2020 Jan 2;4(1):e13224. doi: 10.2196/13224.


Understanding End-User Perspectives of Mobile Pulmonary Rehabilitation (mPR): Cross-Sectional Survey and Interviews.

Dobson R, Herbst P, Candy S, Brott T, Garrett J, Humphrey G, Reeve J, Tawhai M, Taylor D, Warren J, Whittaker R.

JMIR Form Res. 2019 Dec 20;3(4):e15466. doi: 10.2196/15466.


Old-Fashioned Technology in the Era of "Bling": Is There a Future for Text Messaging in Health Care?

Willcox JC, Dobson R, Whittaker R.

J Med Internet Res. 2019 Dec 20;21(12):e16630. doi: 10.2196/16630.


Efficient Reuse of Natural Language Processing Models for Phenotype-Mention Identification in Free-text Electronic Medical Records: A Phenotype Embedding Approach.

Wu H, Hodgson K, Dyson S, Morley KI, Ibrahim ZM, Iqbal E, Stewart R, Dobson RJ, Sudlow C.

JMIR Med Inform. 2019 Dec 17;7(4):e14782. doi: 10.2196/14782.


Distinct genetic changes reveal evolutionary history and heterogeneous molecular grade of DLBCL with MYC/BCL2 double-hit.

Cucco F, Barrans S, Sha C, Clipson A, Crouch S, Dobson R, Chen Z, Thompson JS, Care MA, Cummin T, Caddy J, Liu H, Robinson A, Schuh A, Fitzgibbon J, Painter D, Smith A, Roman E, Tooze R, Burton C, Davies AJ, Westhead DR, Johnson PWM, Du MQ.

Leukemia. 2019 Dec 16. doi: 10.1038/s41375-019-0691-6. [Epub ahead of print]


Association of physical health multimorbidity with mortality in people with schizophrenia spectrum disorders: Using a novel semantic search system that captures physical diseases in electronic patient records.

Kugathasan P, Wu H, Gaughran F, Nielsen RE, Pritchard M, Dobson R, Stewart R, Stubbs B.

Schizophr Res. 2019 Nov 28. pii: S0920-9964(19)30496-7. doi: 10.1016/j.schres.2019.10.061. [Epub ahead of print]


Semantic computational analysis of anticoagulation use in atrial fibrillation from real world data.

Bean DM, Teo J, Wu H, Oliveira R, Patel R, Bendayan R, Shah AM, Dobson RJB, Scott PA.

PLoS One. 2019 Nov 25;14(11):e0225625. doi: 10.1371/journal.pone.0225625. eCollection 2019.


Bleeding in cardiac patients prescribed antithrombotic drugs: electronic health record phenotyping algorithms, incidence, trends and prognosis.

Pasea L, Chung SC, Pujades-Rodriguez M, Shah AD, Alvarez-Madrazo S, Allan V, Teo JT, Bean D, Sofat R, Dobson R, Banerjee A, Patel RS, Timmis A, Denaxas S, Hemingway H.

BMC Med. 2019 Nov 20;17(1):206. doi: 10.1186/s12916-019-1438-y.


Long-term follow-up of a randomized controlled trial of a text-message diabetes self-management support programme, SMS4BG.

Dobson R, Whittaker R, Jiang Y, McNamara C, Shepherd M, Maddison R, Cutfield R, Khanolkar M, Murphy R.

Diabet Med. 2020 Feb;37(2):311-318. doi: 10.1111/dme.14182. Epub 2019 Nov 28.


Natural language processing for disease phenotyping in UK primary care records for research: a pilot study in myocardial infarction and death.

Shah AD, Bailey E, Williams T, Denaxas S, Dobson R, Hemingway H.

J Biomed Semantics. 2019 Nov 12;10(Suppl 1):20. doi: 10.1186/s13326-019-0214-4.


Combining string and phonetic similarity matching to identify misspelt names of drugs in medical records written in Portuguese.

Tissot H, Dobson R.

J Biomed Semantics. 2019 Nov 12;10(Suppl 1):17. doi: 10.1186/s13326-019-0216-2.


On the structure and function of Escherichia coli YjhC: An oxidoreductase involved in bacterial sialic acid metabolism.

Horne CR, Kind L, Davies JS, Dobson RCJ.

Proteins. 2019 Nov 7. doi: 10.1002/prot.25846. [Epub ahead of print]


On the catalytic mechanism of bacteriophage endolysins: Opportunities for engineering.

Love MJ, Abeysekera GS, Muscroft-Taylor AC, Billington C, Dobson RCJ.

Biochim Biophys Acta Proteins Proteom. 2020 Jan;1868(1):140302. doi: 10.1016/j.bbapap.2019.140302. Epub 2019 Oct 31. Review.


The fitness challenge of studying molecular adaptation.

Coombes D, Moir JWB, Poole AM, Cooper TF, Dobson RCJ.

Biochem Soc Trans. 2019 Oct 31;47(5):1533-1542. doi: 10.1042/BST20180626.


Mobile phone text messaging and app-based interventions for smoking cessation.

Whittaker R, McRobbie H, Bullen C, Rodgers A, Gu Y, Dobson R.

Cochrane Database Syst Rev. 2019 Oct 22;10:CD006611. doi: 10.1002/14651858.CD006611.pub5. [Epub ahead of print] Review.


Monitoring secondhand tobacco smoke remotely in real-time: A simple low-cost approach.

Dobson R, Rosen LJ, Semple S.

Tob Induc Dis. 2019 Mar 5;17:18. doi: 10.18332/tid/104577. eCollection 2019.


BCR signaling contributes to autophagy regulation in chronic lymphocytic leukemia.

Smith LD, Minton AR, Blunt MD, Karydis LI, Dutton DA, Rogers-Broadway KR, Dobson R, Liu R, Norster F, Hogg E, Ashton-Key M, Strefford JC, Jia L, Efremov DG, Helgason GV, Johnson PWM, Stevenson FK, Forconi F, Cragg MS, Tumbarello DA, Packham G, Steele AJ.

Leukemia. 2019 Aug 28. doi: 10.1038/s41375-019-0557-y. [Epub ahead of print] No abstract available.


RADAR-Base: Open Source Mobile Health Platform for Collecting, Monitoring, and Analyzing Data Using Sensors, Wearables, and Mobile Devices.

Ranjan Y, Rashid Z, Stewart C, Conde P, Begale M, Verbeeck D, Boettcher S; Hyve, Dobson R, Folarin A; RADAR-CNS Consortium.

JMIR Mhealth Uhealth. 2019 Aug 1;7(8):e11734. doi: 10.2196/11734.


UK phenomics platform for developing and validating electronic health record phenotypes: CALIBER.

Denaxas S, Gonzalez-Izquierdo A, Direk K, Fitzpatrick NK, Fatemifar G, Banerjee A, Dobson RJB, Howe LJ, Kuan V, Lumbers RT, Pasea L, Patel RS, Shah AD, Hingorani AD, Sudlow C, Hemingway H.

J Am Med Inform Assoc. 2019 Dec 1;26(12):1545-1559. doi: 10.1093/jamia/ocz105.


C9orf72 intermediate expansions of 24-30 repeats are associated with ALS.

Iacoangeli A, Al Khleifat A, Jones AR, Sproviero W, Shatunov A, Opie-Martin S; Alzheimer’s Disease Neuroimaging Initiative, Morrison KE, Shaw PJ, Shaw CE, Fogh I, Dobson RJ, Newhouse SJ, Al-Chalabi A.

Acta Neuropathol Commun. 2019 Jul 17;7(1):115. doi: 10.1186/s40478-019-0724-4.


The utility of fluorine-18-fluorodeoxyglucose positron emission tomography in the diagnosis and monitoring of large vessel vasculitis: A South Australian retrospective audit.

Nguyen AD, Crowhurst T, Lester S, Dobson R, Bartholomeusz D, Hill C.

Int J Rheum Dis. 2019 Aug;22(8):1378-1382. doi: 10.1111/1756-185X.13617. Epub 2019 Jun 18.


Continuous Monitoring of Shelf Lives of Materials by Application of Data Loggers with Implemented Kinetic Parameters.

Roduit B, Luyet CA, Hartmann M, Folly P, Sarbach A, Dejeaifve A, Dobson R, Schroeter N, Vorlet O, Dabros M, Baltensperger R.

Molecules. 2019 Jun 13;24(12). pii: E2217. doi: 10.3390/molecules24122217.


Less than full-time training in cardiology.

Dobson R, Joshi A, Allen C, Sinclair HC.

Heart. 2019 Sep;105(18):1445-1446. doi: 10.1136/heartjnl-2019-315226. Epub 2019 May 21. No abstract available.


Differential gene expression analysis in blood of first episode psychosis patients.

Leirer DJ, Iyegbe CO, Di Forti M, Patel H, Carra E, Fraietta S, Colizzi M, Mondelli V, Quattrone D, Lally J, Ajnakina O, Lee SH, Curtis CJ, Breen G, Pariante C, Aitchison K, Dazzan P, Murray RM, Dobson RJB, Newhouse SJ.

Schizophr Res. 2019 Jul;209:88-97. doi: 10.1016/j.schres.2019.05.011. Epub 2019 May 19.


Cross-sectional study of the prevalence, causes and management of hospital-onset diarrhoea.

Mawer D, Byrne F, Drake S, Brown C, Prescott A, Warne B, Bousfield R, Skittrall JP, Ramsay I, Somasunderam D, Bevan M, Coslett J, Rao J, Stanley P, Kennedy A, Dobson R, Long S, Obisanya T, Esmailji T, Petridou C, Saeed K, Brechany K, Davis-Blue K, O'Horan H, Wake B, Martin J, Featherstone J, Hall C, Allen J, Johnson G, Hornigold C, Amir N, Henderson K, McClements C, Liew I, Deshpande A, Vink E, Trigg D, Guilfoyle J, Scarborough M, Scarborough C, Wong THN, Walker T, Fawcett N, Morris G, Tomlin K, Grix C, O'Cofaigh E, McCaffrey D, Cooper M, Corbett K, French K, Harper S, Hayward C, Reid M, Whatley V, Winfield J, Hoque S, Kelly L, King I, Bradley A, McCullagh B, Hibberd C, Merron M, McCabe C, Horridge S, Taylor J, Koo S, Elsanousi F, Saunders R, Lim F, Bond A, Stone S, Milligan ID, Mack DJF, Nagar A, West RM, Wilcox MH, Kirby A, Sandoe JAT.

J Hosp Infect. 2019 Oct;103(2):200-209. doi: 10.1016/j.jhin.2019.05.001. Epub 2019 May 8.


The impact of implementation of a national smoke-free prisons policy on indoor air quality: results from the Tobacco in Prisons study.

Semple S, Dobson R, Sweeting H, Brown A, Hunt K; Tobacco in Prisons (TIPs) research team.

Tob Control. 2019 May 7. pii: tobaccocontrol-2018-054895. doi: 10.1136/tobaccocontrol-2018-054895. [Epub ahead of print]


Transcriptomic analysis of probable asymptomatic and symptomatic alzheimer brains.

Patel H, Hodges AK, Curtis C, Lee SH, Troakes C, Dobson RJB, Newhouse SJ.

Brain Behav Immun. 2019 Aug;80:644-656. doi: 10.1016/j.bbi.2019.05.009. Epub 2019 May 4.


DNAscan: personal computer compatible NGS analysis, annotation and visualisation.

Iacoangeli A, Al Khleifat A, Sproviero W, Shatunov A, Jones AR, Morgan SL, Pittman A, Dobson RJ, Newhouse SJ, Al-Chalabi A.

BMC Bioinformatics. 2019 Apr 27;20(1):213. doi: 10.1186/s12859-019-2791-8.


Oxidative cross-linking of calprotectin occurs in vivo, altering its structure and susceptibility to proteolysis.

Hoskin TS, Crowther JM, Cheung J, Epton MJ, Sly PD, Elder PA, Dobson RCJ, Kettle AJ, Dickerhof N.

Redox Biol. 2019 Jun;24:101202. doi: 10.1016/j.redox.2019.101202. Epub 2019 Apr 13.


Structure-function analyses of two plant meso-diaminopimelate decarboxylase isoforms reveal that active-site gating provides stereochemical control.

Crowther JM, Cross PJ, Oliver MR, Leeman MM, Bartl AJ, Weatherhead AW, North RA, Donovan KA, Griffin MDW, Suzuki H, Hudson AO, Kasanmascheff M, Dobson RCJ.

J Biol Chem. 2019 May 24;294(21):8505-8515. doi: 10.1074/jbc.RA118.006825. Epub 2019 Apr 8.


Informal-sector occupational hazards: an observational workplace assessment of the traditional medicine trade in South Africa.

Shezi B, Naidoo RN, Muttoo S, Mathee A, Alfers L, Dobson R, Ndlovu P, Street RA.

Int J Occup Saf Ergon. 2019 May 24:1-8. doi: 10.1080/10803548.2019.1602329. [Epub ahead of print]


Real World Implementation of a Transdiagnostic Risk Calculator for the Automatic Detection of Individuals at Risk of Psychosis in Clinical Routine: Study Protocol.

Fusar-Poli P, Oliver D, Spada G, Patel R, Stewart R, Dobson R, McGuire P.

Front Psychiatry. 2019 Mar 13;10:109. doi: 10.3389/fpsyt.2019.00109. eCollection 2019.


Telomere length is greater in ALS than in controls: a whole genome sequencing study.

Al Khleifat A, Iacoangeli A, Shatunov A, Fang T, Sproviero W, Jones AR, Opie-Martin S, Morrison KE, Shaw PJ, Shaw CE, Powell JF, Dobson R, Newhouse SJ, Al-Chalabi A.

Amyotroph Lateral Scler Frontotemporal Degener. 2019 May;20(3-4):229-234. doi: 10.1080/21678421.2019.1586951. Epub 2019 Apr 1.


"I just have to take it" - patient safety in acute care: perspectives and experiences of patients with chronic kidney disease.

New L, Goodridge D, Kappel J, Groot G, Dobson R.

BMC Health Serv Res. 2019 Mar 28;19(1):199. doi: 10.1186/s12913-019-4014-4.


A Meta-Analysis of Alzheimer's Disease Brain Transcriptomic Data.

Patel H, Dobson RJB, Newhouse SJ.

J Alzheimers Dis. 2019;68(4):1635-1656. doi: 10.3233/JAD-181085.


Association Between Prerequisites and Academic Success at a Canadian University's Pharmacy Program.

Krol ES, Dobson RT, Adesina K.

Am J Pharm Educ. 2019 Feb;83(1):6491. doi: 10.5688/ajpe6491.


Visibility and representation of women in multiple sclerosis research.

Thomson A, Horne R, Chung C, Marta M, Giovannoni G, Palace J, Dobson R.

Neurology. 2019 Apr 9;92(15):713-719. doi: 10.1212/WNL.0000000000007276. Epub 2019 Mar 20. Review.


The First Purification of Functional Proteins from the Unculturable, Genome-Reduced, Bottlenecked α-Proteobacterium 'Candidatus Liberibacter solanacearum'.

Gilkes JM, Sheen CR, Frampton RA, Smith GR, Dobson RCJ.

Phytopathology. 2019 Jul;109(7):1141-1148. doi: 10.1094/PHYTO-12-18-0486-R. Epub 2019 May 29.


Qualitative exploration of the education and skill needs of community pharmacists in Saskatoon concerning substance use disorder.

Fatani S, Dobson R, El-Aneed A.

Can Pharm J (Ott). 2019 Feb 7;152(2):117-129. doi: 10.1177/1715163518816726. eCollection 2019 Mar-Apr.


Syncope in a new mother: a case of long-QT syndrome presenting after childbirth.

Wereski R, Dobson R, Newman EJ, Connelly D.

J R Coll Physicians Edinb. 2019 Mar;49(1):26-30. doi: 10.4997/JRCPE.2019.105.


ALSgeneScanner: a pipeline for the analysis and interpretation of DNA sequencing data of ALS patients.

Iacoangeli A, Al Khleifat A, Sproviero W, Shatunov A, Jones AR, Opie-Martin S, Naselli E, Topp SD, Fogh I, Hodges A, Dobson RJ, Newhouse SJ, Al-Chalabi A.

Amyotroph Lateral Scler Frontotemporal Degener. 2019 May;20(3-4):207-215. doi: 10.1080/21678421.2018.1562553. Epub 2019 Mar 5.


Remote assessment of disease and relapse in major depressive disorder (RADAR-MDD): a multi-centre prospective cohort study protocol.

Matcham F, Barattieri di San Pietro C, Bulgari V, de Girolamo G, Dobson R, Eriksson H, Folarin AA, Haro JM, Kerz M, Lamers F, Li Q, Manyakov NV, Mohr DC, Myin-Germeys I, Narayan V, Bwjh P, Ranjan Y, Rashid Z, Rintala A, Siddi S, Simblett SK, Wykes T, Hotopf M; RADAR-CNS consortium.

BMC Psychiatry. 2019 Feb 18;19(1):72. doi: 10.1186/s12888-019-2049-z.

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