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Remote assessment of disease and relapse in major depressive disorder (RADAR-MDD): a multi-centre prospective cohort study protocol.

Matcham F, Barattieri di San Pietro C, Bulgari V, de Girolamo G, Dobson R, Eriksson H, Folarin AA, Haro JM, Kerz M, Lamers F, Li Q, Manyakov NV, Mohr DC, Myin-Germeys I, Narayan V, Bwjh P, Ranjan Y, Rashid Z, Rintala A, Siddi S, Simblett SK, Wykes T, Hotopf M; RADAR-CNS consortium.

BMC Psychiatry. 2019 Feb 18;19(1):72. doi: 10.1186/s12888-019-2049-z.


Behavior Change for Youth Drivers: Design and Development of a Smartphone-Based App (BackPocketDriver).

Warren I, Meads A, Whittaker R, Dobson R, Ameratunga S.

JMIR Form Res. 2018 Nov 26;2(2):e25. doi: 10.2196/formative.9660.


The Quest for Novel Antimicrobial Compounds: Emerging Trends in Research, Development, and Technologies.

Mantravadi PK, Kalesh KA, Dobson RCJ, Hudson AO, Parthasarathy A.

Antibiotics (Basel). 2019 Jan 24;8(1). pii: E8. doi: 10.3390/antibiotics8010008. Review.


A patient flow simulator for healthcare management education.

Bean DM, Taylor P, Dobson RJB.

BMJ Simul Technol Enhanc Learn. 2019 Jan;5(1):46-48. doi: 10.1136/bmjstel-2017-000251. Epub 2017 Oct 7.


Chromatic Bacteria - A Broad Host-Range Plasmid and Chromosomal Insertion Toolbox for Fluorescent Protein Expression in Bacteria.

Schlechter RO, Jun H, Bernach M, Oso S, Boyd E, Muñoz-Lintz DA, Dobson RCJ, Remus DM, Remus-Emsermann MNP.

Front Microbiol. 2018 Dec 12;9:3052. doi: 10.3389/fmicb.2018.03052. eCollection 2018.


Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.

Jansen IE, Savage JE, Watanabe K, Bryois J, Williams DM, Steinberg S, Sealock J, Karlsson IK, Hägg S, Athanasiu L, Voyle N, Proitsi P, Witoelar A, Stringer S, Aarsland D, Almdahl IS, Andersen F, Bergh S, Bettella F, Bjornsson S, Brækhus A, Bråthen G, de Leeuw C, Desikan RS, Djurovic S, Dumitrescu L, Fladby T, Hohman TJ, Jonsson PV, Kiddle SJ, Rongve A, Saltvedt I, Sando SB, Selbæk G, Shoai M, Skene NG, Snaedal J, Stordal E, Ulstein ID, Wang Y, White LR, Hardy J, Hjerling-Leffler J, Sullivan PF, van der Flier WM, Dobson R, Davis LK, Stefansson H, Stefansson K, Pedersen NL, Ripke S, Andreassen OA, Posthuma D.

Nat Genet. 2019 Jan 7. doi: 10.1038/s41588-018-0311-9. [Epub ahead of print]


In response to Ballantyne and Schaefer's 'Consent and the ethical duty to participate in health data research'.

Hepgul N, Sleeman KE, Firth AM, Johnston A, Teo JTH, Bernal W, Dobson RJB, Higginson IJ.

J Med Ethics. 2019 Jan 7. pii: medethics-2018-105271. doi: 10.1136/medethics-2018-105271. [Epub ahead of print]


UK consensus on pregnancy in multiple sclerosis: 'Association of British Neurologists' guidelines.

Dobson R, Dassan P, Roberts M, Giovannoni G, Nelson-Piercy C, Brex PA.

Pract Neurol. 2019 Jan 5. pii: practneurol-2018-002060. doi: 10.1136/practneurol-2018-002060. [Epub ahead of print]


Structural and functional analysis of the GABARAP interaction motif (GIM).

Rogov VV, Stolz A, Ravichandran AC, Rios-Szwed DO, Suzuki H, Kniss A, Löhr F, Wakatsuki S, Dötsch V, Dikic I, Dobson RC, McEwan DG.

EMBO Rep. 2018 Dec;19(12). pii: e47268. doi: 10.15252/embr.201847268. No abstract available.


Moving beyond the individual: mHealth tools for social change in low-resource settings.

McCool J, Dobson R, Whittaker R.

BMJ Glob Health. 2018 Nov 21;3(6):e001098. doi: 10.1136/bmjgh-2018-001098. eCollection 2018. No abstract available.


Functional and solution structure studies of amino sugar deacetylase and deaminase enzymes from Staphylococcus aureus.

Davies JS, Coombes D, Horne CR, Pearce FG, Friemann R, North RA, Dobson RCJ.

FEBS Lett. 2019 Jan;593(1):52-66. doi: 10.1002/1873-3468.13289. Epub 2018 Nov 26.


Capturing Rest-Activity Profiles in Schizophrenia Using Wearable and Mobile Technologies: Development, Implementation, Feasibility, and Acceptability of a Remote Monitoring Platform.

Meyer N, Kerz M, Folarin A, Joyce DW, Jackson R, Karr C, Dobson R, MacCabe J.

JMIR Mhealth Uhealth. 2018 Oct 30;6(10):e188. doi: 10.2196/mhealth.8292.


Clinical commentary on 'Life-threatening vitamin D intoxication due to intake of ultra-high doses in multiple sclerosis: a note of caution'.

Dobson R.

Mult Scler. 2018 Oct 25:1352458518807053. doi: 10.1177/1352458518807053. [Epub ahead of print] No abstract available.


Ex-Vivo Signal Transduction Studies in Chronic Lymphocytic Leukemia.

Rogers-Broadway KR, Karydis LI, Dobson RC, Steele AJ.

Methods Mol Biol. 2019;1881:1-17. doi: 10.1007/978-1-4939-8876-1_1.


Multiple sclerosis - a review.

Dobson R, Giovannoni G.

Eur J Neurol. 2019 Jan;26(1):27-40. doi: 10.1111/ene.13819. Epub 2018 Nov 18. Review.


A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes.

Foglizzo M, Middleton AJ, Burgess AE, Crowther JM, Dobson RCJ, Murphy JM, Day CL, Mace PD.

Nat Commun. 2018 Sep 26;9(1):3932. doi: 10.1038/s41467-018-06186-1.


Management of cardiac implantable devices in patients undergoing radiotherapy.

Dobson R, Wright DJ.

Curr Probl Cancer. 2018 Jul;42(4):443-448. doi: 10.1016/j.currproblcancer.2018.06.015. Epub 2018 Jul 18. Review.


Variable Responses of MYC Translocation Positive Lymphoma Cell Lines To Different Combinations of Novel Agents: Impact of BCL2 Family Protein Expression.

Deng W, Clipson A, Liu H, Huang Y, Dobson R, Wang M, Johnson P, Du MQ.

Transl Oncol. 2018 Oct;11(5):1147-1154. doi: 10.1016/j.tranon.2018.07.007. Epub 2018 Jul 25.


The Sodium Sialic Acid Symporter From Staphylococcus aureus Has Altered Substrate Specificity.

North RA, Wahlgren WY, Remus DM, Scalise M, Kessans SA, Dunevall E, Claesson E, Soares da Costa TP, Perugini MA, Ramaswamy S, Allison JR, Indiveri C, Friemann R, Dobson RCJ.

Front Chem. 2018 Jul 4;6:233. doi: 10.3389/fchem.2018.00233. eCollection 2018.


The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics.

Bos I, Vos S, Vandenberghe R, Scheltens P, Engelborghs S, Frisoni G, Molinuevo JL, Wallin A, Lleó A, Popp J, Martinez-Lage P, Baird A, Dobson R, Legido-Quigley C, Sleegers K, Van Broeckhoven C, Bertram L, Ten Kate M, Barkhof F, Zetterberg H, Lovestone S, Streffer J, Visser PJ.

Alzheimers Res Ther. 2018 Jul 6;10(1):64. doi: 10.1186/s13195-018-0396-5.


Crystal structures and kinetic analyses of N-acetylmannosamine-6-phosphate 2-epimerases from Fusobacterium nucleatum and Vibrio cholerae.

Manjunath L, Guntupalli SR, Currie MJ, North RA, Dobson RCJ, Nayak V, Subramanian R.

Acta Crystallogr F Struct Biol Commun. 2018 Jul 1;74(Pt 7):431-440. doi: 10.1107/S2053230X18008543. Epub 2018 Jun 28.


The effectiveness of text message-based self-management interventions for poorly-controlled diabetes: A systematic review.

Dobson R, Whittaker R, Pfaeffli Dale L, Maddison R.

Digit Health. 2017 Nov 9;3:2055207617740315. doi: 10.1177/2055207617740315. eCollection 2017 Jan-Dec. Review.


CogStack - experiences of deploying integrated information retrieval and extraction services in a large National Health Service Foundation Trust hospital.

Jackson R, Kartoglu I, Stringer C, Gorrell G, Roberts A, Song X, Wu H, Agrawal A, Lui K, Groza T, Lewsley D, Northwood D, Folarin A, Stewart R, Dobson R.

BMC Med Inform Decis Mak. 2018 Jun 25;18(1):47. doi: 10.1186/s12911-018-0623-9.


Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain.

Carbajosa G, Malki K, Lawless N, Wang H, Ryder JW, Wozniak E, Wood K, Mein CA, Dobson RJB, Collier DA, O'Neill MJ, Hodges AK, Newhouse SJ.

Neurobiol Aging. 2018 Sep;69:151-166. doi: 10.1016/j.neurobiolaging.2018.04.019. Epub 2018 May 17.


Substrate Locking Promotes Dimer-Dimer Docking of an Enzyme Antibiotic Target.

Atkinson SC, Dogovski C, Wood K, Griffin MDW, Gorman MA, Hor L, Reboul CF, Buckle AM, Wuttke J, Parker MW, Dobson RCJ, Perugini MA.

Structure. 2018 Jul 3;26(7):948-959.e5. doi: 10.1016/j.str.2018.04.014. Epub 2018 May 24.


Effectiveness of text message based, diabetes self management support programme (SMS4BG): two arm, parallel randomised controlled trial.

Dobson R, Whittaker R, Jiang Y, Maddison R, Shepherd M, McNamara C, Cutfield R, Khanolkar M, Murphy R.

BMJ. 2018 May 17;361:k1959. doi: 10.1136/bmj.k1959.


Aurora kinase A (AURKA) interaction with Wnt and Ras-MAPK signalling pathways in colorectal cancer.

Jacobsen A, Bosch LJW, Martens-de Kemp SR, Carvalho B, Sillars-Hardebol AH, Dobson RJ, de Rinaldis E, Meijer GA, Abeln S, Heringa J, Fijneman RJA, Feenstra KA.

Sci Rep. 2018 May 14;8(1):7522. doi: 10.1038/s41598-018-24982-z.


Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site.

Wahlgren WY, Dunevall E, North RA, Paz A, Scalise M, Bisignano P, Bengtsson-Palme J, Goyal P, Claesson E, Caing-Carlsson R, Andersson R, Beis K, Nilsson UJ, Farewell A, Pochini L, Indiveri C, Grabe M, Dobson RCJ, Abramson J, Ramaswamy S, Friemann R.

Nat Commun. 2018 May 1;9(1):1753. doi: 10.1038/s41467-018-04045-7.


Cancer and the heart.

Dobson R, Wright DJ.

Br J Gen Pract. 2018 May;68(670):220-221. doi: 10.3399/bjgp18X695861. No abstract available.


A Three-Ring Circus: Metabolism of the Three Proteogenic Aromatic Amino Acids and Their Role in the Health of Plants and Animals.

Parthasarathy A, Cross PJ, Dobson RCJ, Adams LE, Savka MA, Hudson AO.

Front Mol Biosci. 2018 Apr 6;5:29. doi: 10.3389/fmolb.2018.00029. eCollection 2018. Review.


The self-association and thermal denaturation of caprine and bovine β-lactoglobulin.

Crowther JM, Allison JR, Smolenski GA, Hodgkinson AJ, Jameson GB, Dobson RCJ.

Eur Biophys J. 2018 Oct;47(7):739-750. doi: 10.1007/s00249-018-1300-8. Epub 2018 Apr 16.


Antidepressant drug-specific prediction of depression treatment outcomes from genetic and clinical variables.

Iniesta R, Hodgson K, Stahl D, Malki K, Maier W, Rietschel M, Mors O, Hauser J, Henigsberg N, Dernovsek MZ, Souery D, Dobson R, Aitchison KJ, Farmer A, McGuffin P, Lewis CM, Uher R.

Sci Rep. 2018 Apr 3;8(1):5530. doi: 10.1038/s41598-018-23584-z.


Assessing the implementation processes of a large-scale, multi-year quality improvement initiative: survey of health care providers.

Goodridge D, Rana M, Harrison EL, Rotter T, Dobson R, Groot G, Udod S, Lloyd J.

BMC Health Serv Res. 2018 Apr 3;18(1):237. doi: 10.1186/s12913-018-3045-6.


A Blood Test for Alzheimer's Disease: Progress, Challenges, and Recommendations.

Kiddle SJ, Voyle N, Dobson RJB.

J Alzheimers Dis. 2018;64(s1):S289-S297. doi: 10.3233/JAD-179904.


How to improve the standardization and the diagnostic performance of the fecal egg count reduction test?

Levecke B, Kaplan RM, Thamsborg SM, Torgerson PR, Vercruysse J, Dobson RJ.

Vet Parasitol. 2018 Apr 15;253:71-78. doi: 10.1016/j.vetpar.2018.02.004. Epub 2018 Feb 9.


A Decade of Blood Biomarkers for Alzheimer's Disease Research: An Evolving Field, Improving Study Designs, and the Challenge of Replication.

Shi L, Baird AL, Westwood S, Hye A, Dobson R, Thambisetty M, Lovestone S.

J Alzheimers Dis. 2018;62(3):1181-1198. doi: 10.3233/JAD-170531.


Author Correction: Knowledge graph prediction of unknown adverse drug reactions and validation in electronic health records.

Bean DM, Wu H, Iqbal E, Dzahini O, Ibrahim ZM, Broadbent M, Stewart R, Dobson RJB.

Sci Rep. 2018 Mar 6;8(1):4284. doi: 10.1038/s41598-018-22521-4.


Potential for Bacteriophage Endolysins to Supplement or Replace Antibiotics in Food Production and Clinical Care.

Love MJ, Bhandari D, Dobson RCJ, Billington C.

Antibiotics (Basel). 2018 Feb 27;7(1). pii: E17. doi: 10.3390/antibiotics7010017. Review.


Big data from electronic health records for early and late translational cardiovascular research: challenges and potential.

Hemingway H, Asselbergs FW, Danesh J, Dobson R, Maniadakis N, Maggioni A, van Thiel GJM, Cronin M, Brobert G, Vardas P, Anker SD, Grobbee DE, Denaxas S; Innovative Medicines Initiative 2nd programme, Big Data for Better Outcomes, BigData@Heart Consortium of 20 academic and industry partners including ESC.

Eur Heart J. 2018 Apr 21;39(16):1481-1495. doi: 10.1093/eurheartj/ehx487.


SemEHR: A general-purpose semantic search system to surface semantic data from clinical notes for tailored care, trial recruitment, and clinical research.

Wu H, Toti G, Morley KI, Ibrahim ZM, Folarin A, Jackson R, Kartoglu I, Agrawal A, Stringer C, Gale D, Gorrell G, Roberts A, Broadbent M, Stewart R, Dobson RJB.

J Am Med Inform Assoc. 2018 May 1;25(5):530-537. doi: 10.1093/jamia/ocx160.


"Just a spoonful of sugar...": import of sialic acid across bacterial cell membranes.

North RA, Horne CR, Davies JS, Remus DM, Muscroft-Taylor AC, Goyal P, Wahlgren WY, Ramaswamy S, Friemann R, Dobson RCJ.

Biophys Rev. 2018 Apr;10(2):219-227. doi: 10.1007/s12551-017-0343-x. Epub 2017 Dec 8. Review.


Knowledge graph prediction of unknown adverse drug reactions and validation in electronic health records.

Bean DM, Wu H, Iqbal E, Dzahini O, Ibrahim ZM, Broadbent M, Stewart R, Dobson RJB.

Sci Rep. 2017 Nov 27;7(1):16416. doi: 10.1038/s41598-017-16674-x. Erratum in: Sci Rep. 2018 Mar 6;8(1):4284.


ADEPt, a semantically-enriched pipeline for extracting adverse drug events from free-text electronic health records.

Iqbal E, Mallah R, Rhodes D, Wu H, Romero A, Chang N, Dzahini O, Pandey C, Broadbent M, Stewart R, Dobson RJB, Ibrahim ZM.

PLoS One. 2017 Nov 9;12(11):e0187121. doi: 10.1371/journal.pone.0187121. eCollection 2017.


Effects of Beneficial Mutations in pykF Gene Vary over Time and across Replicate Populations in a Long-Term Experiment with Bacteria.

Peng F, Widmann S, Wünsche A, Duan K, Donovan KA, Dobson RCJ, Lenski RE, Cooper TF.

Mol Biol Evol. 2018 Jan 1;35(1):202-210. doi: 10.1093/molbev/msx279.


Network analysis of patient flow in two UK acute care hospitals identifies key sub-networks for A&E performance.

Bean DM, Stringer C, Beeknoo N, Teo J, Dobson RJB.

PLoS One. 2017 Oct 2;12(10):e0185912. doi: 10.1371/journal.pone.0185912. eCollection 2017.


Vitamin D supplementation.

Dobson R, Cock HR, Brex P, Giovannoni G.

Pract Neurol. 2018 Feb;18(1):35-42. doi: 10.1136/practneurol-2017-001720. Epub 2017 Sep 25. Review.


Synthesis and incorporation of an advanced lipid peroxidation end-product building block into collagen mimetic peptides.

Kavianinia I, Yang SH, Kaur H, Harris PWR, Dobson RCJ, Fairbanks AJ, Brimble MA.

Chem Commun (Camb). 2017 Jul 25;53(60):8459-8462. doi: 10.1039/c7cc05025a.


Structural and functional analysis of the GABARAP interaction motif (GIM).

Rogov VV, Stolz A, Ravichandran AC, Rios-Szwed DO, Suzuki H, Kniss A, Löhr F, Wakatsuki S, Dötsch V, Dikic I, Dobson RC, McEwan DG.

EMBO Rep. 2017 Aug;18(8):1382-1396. doi: 10.15252/embr.201643587. Epub 2017 Jun 27. Erratum in: EMBO Rep. 2018 Dec;19(12):.


Trajectories of dementia-related cognitive decline in a large mental health records derived patient cohort.

Baker E, Iqbal E, Johnston C, Broadbent M, Shetty H, Stewart R, Howard R, Newhouse S, Khondoker M, Dobson RJB.

PLoS One. 2017 Jun 7;12(6):e0178562. doi: 10.1371/journal.pone.0178562. eCollection 2017.

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