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Items: 1 to 50 of 62

1.

How Can Interleukin-1 Receptor Antagonist Modulate Distinct Cell Death Pathways?

Spinello A, Vecile E, Abbate A, Dobrina A, Magistrato A.

J Chem Inf Model. 2019 Jan 28;59(1):351-359. doi: 10.1021/acs.jcim.8b00565. Epub 2019 Jan 10.

2.

Five-year-term results in cirrhotics without varices, either affected or not by portal hypertensive gastropathy.

Zardi EM, Pipita ME, Lichinchi D, Dobrina A.

Eur J Gastroenterol Hepatol. 2019 Apr;31(4):528-533. doi: 10.1097/MEG.0000000000001333.

PMID:
30531405
3.

Portopulmonary hypertension and hepatorenal syndrome. Two faces of the same coin.

Zardi EM, Zardi DM, Giorgi C, Chin D, Dobrina A.

Eur J Intern Med. 2017 Sep;43:22-27. doi: 10.1016/j.ejim.2017.05.028. Epub 2017 Jun 3. Review.

PMID:
28583409
4.

Cirrhotic cardiomyopathy in the pre- and post-liver transplantation phase.

Zardi EM, Zardi DM, Chin D, Sonnino C, Dobrina A, Abbate A.

J Cardiol. 2016 Feb;67(2):125-30. doi: 10.1016/j.jjcc.2015.04.016. Epub 2015 Jun 11. Review.

5.

Hepatic PPARs: their role in liver physiology, fibrosis and treatment.

Zardi EM, Navarini L, Sambataro G, Piccinni P, Sambataro FM, Spina C, Dobrina A.

Curr Med Chem. 2013;20(27):3370-96. Review.

PMID:
23746272
6.

Intracellular function of interleukin-1 receptor antagonist in ischemic cardiomyocytes.

Vecile E, Dobrina A, Salloum FN, Van Tassell BW, Falcione A, Gustini E, Secchiero S, Crovella S, Sinagra G, Finato N, Nicklin MJ, Abbate A.

PLoS One. 2013;8(1):e53265. doi: 10.1371/journal.pone.0053265. Epub 2013 Jan 8.

7.

Alterations in the interleukin-1/interleukin-1 receptor antagonist balance modulate cardiac remodeling following myocardial infarction in the mouse.

Abbate A, Salloum FN, Van Tassell BW, Vecile E, Toldo S, Seropian I, Mezzaroma E, Dobrina A.

PLoS One. 2011;6(11):e27923. doi: 10.1371/journal.pone.0027923. Epub 2011 Nov 28.

8.

Cirrhotic cardiomyopathy.

Zardi EM, Abbate A, Zardi DM, Dobrina A, Margiotta D, Van Tassell BW, Afeltra A, Sanyal AJ.

J Am Coll Cardiol. 2010 Aug 10;56(7):539-49. doi: 10.1016/j.jacc.2009.12.075. Review. Erratum in: J Am Coll Cardiol. 2010 Sep 14;56(12):1000. Van Tassel, Benjamin W [corrected to Van Tassell, Benjamin W].

9.

Portosystemic shunts in a large cohort of patients with liver cirrhosis: detection rate and clinical relevance.

Zardi EM, Uwechie V, Caccavo D, Pellegrino NM, Cacciapaglia F, Di Matteo F, Dobrina A, Laghi V, Afeltra A.

J Gastroenterol. 2009;44(1):76-83. doi: 10.1007/s00535-008-2279-1. Epub 2009 Jan 22.

PMID:
19159076
10.

Endothelin-1 induces connective tissue growth factor expression in cardiomyocytes.

Recchia AG, Filice E, Pellegrino D, Dobrina A, Cerra MC, Maggiolini M.

J Mol Cell Cardiol. 2009 Mar;46(3):352-9. doi: 10.1016/j.yjmcc.2008.11.017. Epub 2008 Dec 10.

PMID:
19111553
11.

Postmeal portal flow variations in HCV-related chronic hepatitis and liver cirrhosis with and without hyperdynamic syndrome.

Zardi EM, Dobrina A, Uwechie V, Cacciapaglia F, Rollo M, Laghi V, Ambrosino G, Lumachi F.

In Vivo. 2008 Jul-Aug;22(4):509-12.

12.

New therapeutic approaches to liver fibrosis: a practicable route?

Zardi EM, Dobrina A, Ambrosino G, Margiotta D, Polistina F, Afeltra A.

Curr Med Chem. 2008;15(16):1628-44. Review.

PMID:
18673229
13.

Anakinra, a recombinant human interleukin-1 receptor antagonist, inhibits apoptosis in experimental acute myocardial infarction.

Abbate A, Salloum FN, Vecile E, Das A, Hoke NN, Straino S, Biondi-Zoccai GG, Houser JE, Qureshi IZ, Ownby ED, Gustini E, Biasucci LM, Severino A, Capogrossi MC, Vetrovec GW, Crea F, Baldi A, Kukreja RC, Dobrina A.

Circulation. 2008 May 20;117(20):2670-83. doi: 10.1161/CIRCULATIONAHA.107.740233. Epub 2008 May 12.

PMID:
18474815
14.

Sudden coronary death, fatal acute myocardial infarction and widespread coronary and myocardial inflammation.

Abbate A, Bussani R, Liuzzo G, Biondi-Zoccai GG, Barresi E, Mellone P, Sinagra G, Dobrina A, De Giorgio F, Sharma R, Bassan F, Severino A, Baldi F, Biasucci LM, Pandolfi F, Silvestri F, Vetrovec GW, Baldi A, Crea F.

Heart. 2008 Jun;94(6):737-42. Epub 2007 Aug 13.

PMID:
17698556
15.

Prostacyclin in liver disease: a potential therapeutic option.

Zardi EM, Dobrina A, Amoroso A, Afeltra A.

Expert Opin Biol Ther. 2007 Jun;7(6):785-90. Review.

PMID:
17555364
16.

Portal diameter in the diagnosis of esophageal varices in 266 cirrhotic patients: which role?

Zardi EM, Uwechie V, Gentilucci UV, Dobrina A, Petitti T, Laghi V, Picardi A, Afeltra A.

Ultrasound Med Biol. 2007 Apr;33(4):506-11.

PMID:
17337112
17.

Prostacyclin in sepsis: a systematic review.

Zardi EM, Zardi DM, Dobrina A, Afeltra A.

Prostaglandins Other Lipid Mediat. 2007 Feb;83(1-2):1-24. Epub 2006 Dec 29. Review.

PMID:
17259068
18.

Iloprost enhances portal flow velocity and volume in patients with systemic sclerosis.

Zardi EM, Picardi A, Ambrosino G, Fazio VM, Dobrina A, Frego M, Afeltra A, Lumachi F.

In Vivo. 2006 May-Jun;20(3):377-80.

19.

Interleukin-1 receptor antagonist levels correlate with extent of myocardial loss in patients with acute myocardial infarction.

Patti G, Mega S, Pasceri V, Nusca A, Giorgi G, Zardi EM, D'Ambrosio A, Dobrina A, Di Sciascio G.

Clin Cardiol. 2005 Apr;28(4):193-6.

20.

Endothelial dysfunction and activation as an expression of disease: role of prostacyclin analogs.

Zardi EM, Zardi DM, Cacciapaglia F, Dobrina A, Amoroso A, Picardi A, Afeltra A.

Int Immunopharmacol. 2005 Mar;5(3):437-59. Review.

PMID:
15683843
21.

Genotypes and haplotypes in the IL-1 gene cluster: analysis of two genetically and diagnostically distinct groups of Alzheimer patients.

Seripa D, Matera MG, Dal Forno G, Gravina C, Masullo C, Daniele A, Binetti G, Bonvicini C, Squitti R, Palermo MT, Davis DG, Antuono P, Wekstein DR, Dobrina A, Gennarelli M, Fazio VM.

Neurobiol Aging. 2005 Apr;26(4):455-64.

PMID:
15653174
22.

Iloprost: an adjunctive approach to chronic viral hepatitis treatment.

Zardi EM, Vespasiani Gentilucci U, Picardi A, Ambrosino G, Fazio VM, Dobrina A, Afeltra A.

Med Hypotheses. 2005;64(1):46-52.

PMID:
15533610
23.

Assessment of systemic inflammation and infective pathogen burden in patients with cardiac syndrome X.

Lanza GA, Sestito A, Cammarota G, Grillo RL, Vecile E, Cianci R, Speziale D, Dobrina A, Maseri A, Crea F.

Am J Cardiol. 2004 Jul 1;94(1):40-4.

PMID:
15219506
24.

Widespread myocardial inflammation and infarct-related artery patency.

Abbate A, Bonanno E, Mauriello A, Bussani R, Biondi-Zoccai GG, Liuzzo G, Leone AM, Silvestri F, Dobrina A, Baldi F, Pandolfi F, Biasucci LM, Baldi A, Spagnoli LG, Crea F.

Circulation. 2004 Jul 6;110(1):46-50. Epub 2004 Jun 21.

PMID:
15210601
25.

Improved hepatic perfusion after iloprost infusion in patients with HCV chronic infection: a pilot study with possible therapeutic implications.

Zardi EM, Picardi A, Fazio VM, Ambrosino G, Dobrina A, Zullo M, Zennaro D, Afeltra A.

J Interferon Cytokine Res. 2004 May;24(5):297-300.

PMID:
15153313
26.

Enhanced portal flow velocity and volume following Iloprost treatment.

Zardi EM, Picardi A, Ambrosino G, Fazio VM, Dobrina A, Afeltra A, Frego M.

Acta Biomed. 2003;74 Suppl 2:108-10.

PMID:
15055047
27.

Early interleukin-1 receptor antagonist elevation in patients with acute myocardial infarction.

Patti G, D'Ambrosio A, Mega S, Giorgi G, Zardi EM, Zardi DM, Dicuonzo G, Dobrina A, Di Sciascio G.

J Am Coll Cardiol. 2004 Jan 7;43(1):35-8.

28.

Soluble interleukin-2 receptor: is there a role in ischaemic cardiomyopathy?

Abbate A, Biondi-Zoccai GG, Vecile E, Dobrina A.

Eur J Clin Invest. 2003 Nov;33(11):1020; author reply 1021. No abstract available.

PMID:
14636309
29.

Right ventricular dilatation after left ventricular acute myocardial infarction is predictive of extremely high peri-infarctual apoptosis at postmortem examination in humans.

Bussani R, Abbate A, Biondi-Zoccai GG, Dobrina A, Leone AM, Camilot D, Di Marino MP, Baldi F, Silvestri F, Biasucci LM, Baldi A.

J Clin Pathol. 2003 Sep;56(9):672-6.

30.

High-risk clinical features predict increased post-infarction myocardial apoptosis and the benefits as a result of an open infarct-related artery.

Abbate A, Biondi-Zoccai GG, Bussani R, Camilot D, Dobrina A, Leone AM, Baldi F, Silvestri F, Biasucci LM, Baldi A.

Eur J Clin Invest. 2003 Aug;33(8):662-8.

PMID:
12864776
31.

Interleukin-1 receptor antagonist: a sensitive marker of instability in patients with coronary artery disease.

Patti G, D'Ambrosio A, Dobrina A, Dicuonzo G, Giansante C, Fiotti N, Abbate A, Guarnieri G, Di Sciascio G.

J Thromb Thrombolysis. 2002 Oct;14(2):139-43.

PMID:
12714833
32.

Relevance of interleukin-1 receptor antagonist intron-2 polymorphism in ischemic stroke.

Seripa D, Dobrina A, Margaglione M, Matera MG, Gravina C, Vecile E, Fazio VM.

Cerebrovasc Dis. 2003;15(4):276-81.

PMID:
12686792
33.

Evidence of CXC, CC and C chemokine production by lymphatic endothelial cells.

Mancardi S, Vecile E, Dusetti N, Calvo E, Stanta G, Burrone OR, Dobrina A.

Immunology. 2003 Apr;108(4):523-30.

34.

Hemodynamic effects of a prostacyclin analog (iloprost) on portal flow velocity and volume and visceral artery circulation in patients with lower limb arteriopathy.

Zardi EM, Picardi A, Ambrosino G, Serio A, Costantino S, Dobrina A.

Ultrasound Med Biol. 2003 Feb;29(2):209-13.

PMID:
12659908
35.

Increased myocardial apoptosis in patients with unfavorable left ventricular remodeling and early symptomatic post-infarction heart failure.

Abbate A, Biondi-Zoccai GG, Bussani R, Dobrina A, Camilot D, Feroce F, Rossiello R, Baldi F, Silvestri F, Biasucci LM, Baldi A.

J Am Coll Cardiol. 2003 Mar 5;41(5):753-60.

36.

Plasma concentrations of interleukin-2 soluble receptor in mild ischaemic left ventricular dysfunction.

Abbate A, Vecile E, Fiotti N, Giansante C, Guarnieri G, Di Sciascio G, Dobrina A.

Eur J Heart Fail. 2003 Jan;5(1):23-5. No abstract available.

37.

Inflammatory markers and coronary interventions: a potentially useful follow-up modality after stenting.

Patti G, Di Sciascio G, D'Ambrosio A, Dicuonzo G, Abbate A, Dobrina A.

Catheter Cardiovasc Interv. 2002 Jul;56(3):341-5.

PMID:
12112886
38.

Apoptosis and post-infarction left ventricular remodeling.

Baldi A, Abbate A, Bussani R, Patti G, Melfi R, Angelini A, Dobrina A, Rossiello R, Silvestri F, Baldi F, Di Sciascio G.

J Mol Cell Cardiol. 2002 Feb;34(2):165-74.

PMID:
11851356
39.

Prognostic value of interleukin-1 receptor antagonist in patients undergoing percutaneous coronary intervention.

Patti G, Di Sciascio G, D'Ambrosio A, Dicuonzo G, Abbate A, Dobrina A.

Am J Cardiol. 2002 Feb 15;89(4):372-6.

PMID:
11835913
40.

Cytolytically inactive terminal complement complex causes transendothelial migration of polymorphonuclear leukocytes in vitro and in vivo.

Dobrina A, Pausa M, Fischetti F, Bulla R, Vecile E, Ferrero E, Mantovani A, Tedesco F.

Blood. 2002 Jan 1;99(1):185-92.

41.

Complement-endothelial cell interactions: pathophysiological implications.

Tedesco F, Fischetti F, Pausa M, Dobrina A, Sim RB, Daha MR.

Mol Immunol. 2000 Jan;37(1-2):91. No abstract available.

PMID:
10781839
43.

Atherosclerosis and inflammation. Patterns of cytokine regulation in patients with peripheral arterial disease.

Fiotti N, Giansante C, Ponte E, Delbello C, Calabrese S, Zacchi T, Dobrina A, Guarnieri G.

Atherosclerosis. 1999 Jul;145(1):51-60.

PMID:
10428295
44.

Complement-endothelial cell interactions: pathophysiological implications.

Tedesco F, Fischetti F, Pausa M, Dobrina A, Sim RB, Daha MR.

Mol Immunol. 1999 Mar-Apr;36(4-5):261-8. Review.

PMID:
10403479
45.

Endothelial cell E- and P-selectin and vascular cell adhesion molecule-1 function as signaling receptors.

Lorenzon P, Vecile E, Nardon E, Ferrero E, Harlan JM, Tedesco F, Dobrina A.

J Cell Biol. 1998 Sep 7;142(5):1381-91.

46.
47.

Leptospira interrogans and Leptospira peptidoglycans induce the release of tumor necrosis factor alpha from human monocytes.

Cinco M, Vecile E, Murgia R, Dobrina P, Dobrina A.

FEMS Microbiol Lett. 1996 May 1;138(2-3):211-4.

PMID:
9026448
48.
49.

Biological activity of a peptidoglycan extracted from Leptospira interrogans: in vitro studies.

Cinco M, Perticarari S, Presani G, Dobrina A, Liut F.

J Gen Microbiol. 1993 Dec;139(12):2959-64.

PMID:
8126423
50.

Effects of endotoxin in mice bearing solid metastasizing tumors and treated with lysozyme hydrochloride.

Sava G, Pacor S, Nardon E, Dobrina A.

J Chemother. 1992 Aug;4(4):228-34.

PMID:
1403079

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