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Items: 39

1.

Lamin B1 in cancer and aging.

Garvalov BK, Muhammad S, Dobreva G.

Aging (Albany NY). 2019 Sep 20;11(18):7336-7338. doi: 10.18632/aging.102306. Epub 2019 Sep 20. No abstract available.

2.

Induction of cardiomyocyte proliferation and angiogenesis protects neonatal mice from pressure overload-associated maladaptation.

Malek Mohammadi M, Abouissa A, Azizah I, Xie Y, Cordero J, Shirvani A, Gigina A, Engelhardt M, Trogisch FA, Geffers R, Dobreva G, Bauersachs J, Heineke J.

JCI Insight. 2019 Jul 23;5. pii: 128336. doi: 10.1172/jci.insight.128336.

3.

Inactivation of Sox9 in fibroblasts reduces cardiac fibrosis and inflammation.

Scharf GM, Kilian K, Cordero J, Wang Y, Grund A, Hofmann M, Froese N, Wang X, Kispert A, Kist R, Conway SJ, Geffers R, Wollert KC, Dobreva G, Bauersachs J, Heineke J.

JCI Insight. 2019 Jul 16;5. pii: 126721. doi: 10.1172/jci.insight.126721.

4.

Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis.

Rubio K, Singh I, Dobersch S, Sarvari P, Günther S, Cordero J, Mehta A, Wujak L, Cabrera-Fuentes H, Chao CM, Braubach P, Bellusci S, Seeger W, Günther A, Preissner KT, Wygrecka M, Savai R, Papy-Garcia D, Dobreva G, Heikenwalder M, Savai-Pullamsetti S, Braun T, Barreto G.

Nat Commun. 2019 May 20;10(1):2229. doi: 10.1038/s41467-019-10066-7.

5.

Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate.

Gao R, Liang X, Cheedipudi S, Cordero J, Jiang X, Zhang Q, Caputo L, Günther S, Kuenne C, Ren Y, Bhattacharya S, Yuan X, Barreto G, Chen Y, Braun T, Evans SM, Sun Y, Dobreva G.

Cell Res. 2019 Jun;29(6):486-501. doi: 10.1038/s41422-019-0168-1. Epub 2019 Apr 25.

6.

Lamin B1 loss promotes lung cancer development and metastasis by epigenetic derepression of RET.

Jia Y, Vong JS, Asafova A, Garvalov BK, Caputo L, Cordero J, Singh A, Boettger T, Günther S, Fink L, Acker T, Barreto G, Seeger W, Braun T, Savai R, Dobreva G.

J Exp Med. 2019 Jun 3;216(6):1377-1395. doi: 10.1084/jem.20181394. Epub 2019 Apr 23.

7.

Delineating the Dynamic Transcriptome Response of mRNA and microRNA during Zebrafish Heart Regeneration.

Klett H, Jürgensen L, Most P, Busch M, Günther F, Dobreva G, Leuschner F, Hassel D, Busch H, Boerries M.

Biomolecules. 2018 Dec 28;9(1). pii: E11. doi: 10.3390/biom9010011.

8.

MiCEE is a ncRNA-protein complex that mediates epigenetic silencing and nucleolar organization.

Singh I, Contreras A, Cordero J, Rubio K, Dobersch S, Günther S, Jeratsch S, Mehta A, Krüger M, Graumann J, Seeger W, Dobreva G, Braun T, Barreto G.

Nat Genet. 2018 Jul;50(7):990-1001. doi: 10.1038/s41588-018-0139-3. Epub 2018 Jun 4.

PMID:
29867223
9.

Disruption of spatiotemporal hypoxic signaling causes congenital heart disease in mice.

Yuan X, Qi H, Li X, Wu F, Fang J, Bober E, Dobreva G, Zhou Y, Braun T.

J Clin Invest. 2017 Jun 1;127(6):2235-2248. doi: 10.1172/JCI88725. Epub 2017 Apr 24.

10.

Isl2b regulates anterior second heart field development in zebrafish.

Witzel HR, Cheedipudi S, Gao R, Stainier DY, Dobreva GD.

Sci Rep. 2017 Jan 20;7:41043. doi: 10.1038/srep41043.

11.

Non-invasive lung cancer diagnosis by detection of GATA6 and NKX2-1 isoforms in exhaled breath condensate.

Mehta A, Cordero J, Dobersch S, Romero-Olmedo AJ, Savai R, Bodner J, Chao CM, Fink L, Guzmán-Díaz E, Singh I, Dobreva G, Rapp UR, Günther S, Ilinskaya ON, Bellusci S, Dammann RH, Braun T, Seeger W, Gattenlöhner S, Tresch A, Günther A, Barreto G.

EMBO Mol Med. 2016 Dec 1;8(12):1380-1389. doi: 10.15252/emmm.201606382. Print 2016 Dec.

12.

The Isl1/Ldb1 Complex Orchestrates Genome-wide Chromatin Organization to Instruct Differentiation of Multipotent Cardiac Progenitors.

Caputo L, Witzel HR, Kolovos P, Cheedipudi S, Looso M, Mylona A, van IJcken WF, Laugwitz KL, Evans SM, Braun T, Soler E, Grosveld F, Dobreva G.

Cell Stem Cell. 2015 Sep 3;17(3):287-99. doi: 10.1016/j.stem.2015.08.007. Epub 2015 Aug 27.

13.

The transcriptional landscape of regenerating newborn mouse hearts.

Dobreva G, Braun T.

Circ Res. 2015 Feb 27;116(5):767-9. doi: 10.1161/CIRCRESAHA.115.305918. No abstract available.

PMID:
25722436
14.

Direct nkx2-5 transcriptional repression of isl1 controls cardiomyocyte subtype identity.

Dorn T, Goedel A, Lam JT, Haas J, Tian Q, Herrmann F, Bundschu K, Dobreva G, Schiemann M, Dirschinger R, Guo Y, Kühl SJ, Sinnecker D, Lipp P, Laugwitz KL, Kühl M, Moretti A.

Stem Cells. 2015 Apr;33(4):1113-29. doi: 10.1002/stem.1923.

15.

Satb2 Regulates the Differentiation of Both Callosal and Subcerebral Projection Neurons in the Developing Cerebral Cortex.

Leone DP, Heavner WE, Ferenczi EA, Dobreva G, Huguenard JR, Grosschedl R, McConnell SK.

Cereb Cortex. 2015 Oct;25(10):3406-19. doi: 10.1093/cercor/bhu156. Epub 2014 Jul 17.

16.

Epigenetic inheritance of cell fates during embryonic development.

Cheedipudi S, Genolet O, Dobreva G.

Front Genet. 2014 Feb 4;5:19. doi: 10.3389/fgene.2014.00019. eCollection 2014. Review.

17.

Jmjd3 controls mesodermal and cardiovascular differentiation of embryonic stem cells.

Ohtani K, Zhao C, Dobreva G, Manavski Y, Kluge B, Braun T, Rieger MA, Zeiher AM, Dimmeler S.

Circ Res. 2013 Sep 13;113(7):856-62. doi: 10.1161/CIRCRESAHA.113.302035. Epub 2013 Jul 15.

PMID:
23856522
18.

A network of genetic repression and derepression specifies projection fates in the developing neocortex.

Srinivasan K, Leone DP, Bateson RK, Dobreva G, Kohwi Y, Kohwi-Shigematsu T, Grosschedl R, McConnell SK.

Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19071-8. doi: 10.1073/pnas.1216793109. Epub 2012 Nov 9.

19.

The LIM protein Ajuba restricts the second heart field progenitor pool by regulating Isl1 activity.

Witzel HR, Jungblut B, Choe CP, Crump JG, Braun T, Dobreva G.

Dev Cell. 2012 Jul 17;23(1):58-70. doi: 10.1016/j.devcel.2012.06.005. Epub 2012 Jul 5.

20.

When silence is broken: polycomb group proteins in heart development.

Dobreva G, Braun T.

Circ Res. 2012 Feb 3;110(3):372-4. doi: 10.1161/CIRCRESAHA.111.263145. No abstract available.

PMID:
22302750
21.

Early B cell factor 2 regulates hematopoietic stem cell homeostasis in a cell-nonautonomous manner.

Kieslinger M, Hiechinger S, Dobreva G, Consalez GG, Grosschedl R.

Cell Stem Cell. 2010 Oct 8;7(4):496-507. doi: 10.1016/j.stem.2010.07.015.

22.

The yin and yang of polycomb repression in regenerating muscle.

Dobreva G, Braun T.

Cell Stem Cell. 2010 Oct 8;7(4):422-4. doi: 10.1016/j.stem.2010.09.005.

23.

Satb2 regulates callosal projection neuron identity in the developing cerebral cortex.

Alcamo EA, Chirivella L, Dautzenberg M, Dobreva G, Fariñas I, Grosschedl R, McConnell SK.

Neuron. 2008 Feb 7;57(3):364-77. doi: 10.1016/j.neuron.2007.12.012.

24.

Action of Humicola lanuginosa lipase on mixed monomolecular films of tricaprylin and polyethylene glycol stearate.

Ivanova T, Mircheva K, Dobreva G, Panaiotov I, Proust JE, Verger R.

Colloids Surf B Biointerfaces. 2008 May 1;63(1):91-100. doi: 10.1016/j.colsurfb.2007.11.004. Epub 2007 Nov 21.

PMID:
18178069
25.

SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation.

Dobreva G, Chahrour M, Dautzenberg M, Chirivella L, Kanzler B, Fariñas I, Karsenty G, Grosschedl R.

Cell. 2006 Jun 2;125(5):971-86.

26.

EBF2 regulates osteoblast-dependent differentiation of osteoclasts.

Kieslinger M, Folberth S, Dobreva G, Dorn T, Croci L, Erben R, Consalez GG, Grosschedl R.

Dev Cell. 2005 Dec;9(6):757-67.

27.

SUMO modification of a novel MAR-binding protein, SATB2, modulates immunoglobulin mu gene expression.

Dobreva G, Dambacher J, Grosschedl R.

Genes Dev. 2003 Dec 15;17(24):3048-61.

28.

Glycine activates myenteric neurones in adult guinea-pigs.

Neunlist M, Michel K, Reiche D, Dobreva G, Huber K, Schemann M.

J Physiol. 2001 Nov 1;536(Pt 3):727-39.

29.

TIF-IA, the factor mediating growth-dependent control of ribosomal RNA synthesis, is the mammalian homolog of yeast Rrn3p.

Bodem J, Dobreva G, Hoffmann-Rohrer U, Iben S, Zentgraf H, Delius H, Vingron M, Grummt I.

EMBO Rep. 2000 Aug;1(2):171-5.

30.

Protein C activity in patients with antiphospholipid syndrome.

Boyanovski B, Russeva M, Dobreva G, Ganev V, Mladenova A, Peicheva V, Nikolov K, Baleva M.

J Clin Rheumatol. 2000 Oct;6(5):239-43.

PMID:
19078479
31.

Characteristics of mucosally projecting myenteric neurones in the guinea-pig proximal colon.

Neunlist M, Dobreva G, Schemann M.

J Physiol. 1999 Jun 1;517 ( Pt 2):533-46.

32.

Different tachykinin receptors mediate chloride secretion in the distal colon through activation of submucosal neurones.

Frieling T, Dobreva G, Weber E, Becker K, Rupprecht C, Neunlist M, Schemann M.

Naunyn Schmiedebergs Arch Pharmacol. 1999 Jan;359(1):71-9.

PMID:
9933154
33.

Post- and presynaptic effects of norepinephrine in guinea-pig colonic submucous plexus.

Dobreva G, Neunlist M, Frieling T, Schemann M.

Neurogastroenterol Motil. 1998 Apr;10(2):123-30.

PMID:
9614670
34.

Differential effects of inflammatory mediators on ion secretion in the guinea-pig colon.

Frieling T, Rupprecht C, Dobreva G, Schemann M.

Comp Biochem Physiol A Physiol. 1997 Oct;118(2):341-3.

PMID:
9366066
35.

Leukotriene-evoked cyclic chloride secretion is mediated by enteric neuronal modulation in guinea-pig colon.

Frieling T, Becker K, Rupprecht C, Dobreva G, Häussinger D, Schemann M.

Naunyn Schmiedebergs Arch Pharmacol. 1997 May;355(5):625-30.

PMID:
9151302
36.

Nitric oxide modulates cholinergic neurotransmission in cat duodenum.

Sotirov E, Dobreva G, Noeva A, Papasova M.

Gen Pharmacol. 1996 Mar;27(2):395-8.

PMID:
8919663
37.

Effects of prostaglandin F2 alpha (PGF2 alpha) and prostaglandin I2 (PGI2) on nerve-mediated secretion in guinea-pig colon.

Frieling T, Rupprecht C, Dobreva G, Häussinger D, Schemann M.

Pflugers Arch. 1995 Dec;431(2):212-20.

PMID:
9026781
38.

Some characteristics of the muscularis mucosae of the cat lower esophageal sphincter.

Dobreva G, Mizhorkova Z, Kortezova N, Papasova M.

Gen Pharmacol. 1994 Jul;25(4):639-43.

PMID:
7958723
39.

Character of the nerve transmission in different stomach regions.

Dobreva G, Bayginov O, Atanassova E.

Acta Physiol Pharmacol Bulg. 1982;8(3):45-51.

PMID:
6303051

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