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Items: 1 to 50 of 113

1.

Cell transformation by the adenovirus oncogenes E1 and E4.

Ip WH, Dobner T.

FEBS Lett. 2019 Dec 10. doi: 10.1002/1873-3468.13717. [Epub ahead of print] Review.

PMID:
31821536
2.

The Ubiquitin-Specific Protease Usp7, a Novel Merkel Cell Polyomavirus Large T-Antigen Interaction Partner, Modulates Viral DNA Replication.

Czech-Sioli M, Siebels S, Radau S, Zahedi RP, Schmidt C, Dobner T, Grundhoff A, Fischer N.

J Virol. 2020 Feb 14;94(5). pii: e01638-19. doi: 10.1128/JVI.01638-19. Print 2020 Feb 14.

PMID:
31801860
3.

The biology of the adenovirus E1B 55K protein.

Hidalgo P, Ip WH, Dobner T, Gonzalez RA.

FEBS Lett. 2019 Dec;593(24):3504-3517. doi: 10.1002/1873-3468.13694. Epub 2019 Dec 8. Review.

PMID:
31769868
4.

The human adenovirus type 5 E1B 55kDa protein interacts with RNA promoting timely DNA replication and viral late mRNA metabolism.

Tejera B, López RE, Hidalgo P, Cárdenas R, Ballesteros G, Rivillas L, French L, Amero C, Pastor N, Santiago Á, Groitl P, Dobner T, Gonzalez RA.

PLoS One. 2019 Apr 3;14(4):e0214882. doi: 10.1371/journal.pone.0214882. eCollection 2019.

5.

Molecular Evolution of Human Adenovirus (HAdV) Species C.

Dhingra A, Hage E, Ganzenmueller T, Böttcher S, Hofmann J, Hamprecht K, Obermeier P, Rath B, Hausmann F, Dobner T, Heim A.

Sci Rep. 2019 Jan 31;9(1):1039. doi: 10.1038/s41598-018-37249-4.

6.

E1B-55K-Mediated Regulation of RNF4 SUMO-Targeted Ubiquitin Ligase Promotes Human Adenovirus Gene Expression.

Müncheberg S, Hay RT, Ip WH, Meyer T, Weiß C, Brenke J, Masser S, Hadian K, Dobner T, Schreiner S.

J Virol. 2018 Jun 13;92(13). pii: e00164-18. doi: 10.1128/JVI.00164-18. Print 2018 Jul 1.

7.

Degradation of a Novel DNA Damage Response Protein, Tankyrase 1 Binding Protein 1, following Adenovirus Infection.

Chalabi Hagkarim N, Ryan EL, Byrd PJ, Hollingworth R, Shimwell NJ, Agathanggelou A, Vavasseur M, Kolbe V, Speiseder T, Dobner T, Stewart GS, Grand RJ.

J Virol. 2018 May 29;92(12). pii: e02034-17. doi: 10.1128/JVI.02034-17. Print 2018 Jun 15.

8.

Broad-spectrum antiviral activity of the deubiquitinase inhibitor HBX against human adenoviruses

Kosulin K, Lam E, Heim A, Dobner T, Rodríguez E.

Antivir Ther. 2018;23(6):475-483. doi: 10.3851/IMP3230.

PMID:
29557344
9.

Human Adenovirus Core Protein V Is Targeted by the Host SUMOylation Machinery To Limit Essential Viral Functions.

Freudenberger N, Meyer T, Groitl P, Dobner T, Schreiner S.

J Virol. 2018 Jan 30;92(4). pii: e01451-17. doi: 10.1128/JVI.01451-17. Print 2018 Feb 15.

10.

Humanized Mice Reproduce Acute and Persistent Human Adenovirus Infection.

Rodríguez E, Ip WH, Kolbe V, Hartmann K, Pilnitz-Stolze G, Tekin N, Gómez-Medina S, Muñoz-Fontela C, Krasemann S, Dobner T.

J Infect Dis. 2017 Jan 1;215(1):70-79. doi: 10.1093/infdis/jiw499. Epub 2016 Oct 17.

PMID:
28077585
11.

Efficient Transformation of Primary Human Mesenchymal Stromal Cells by Adenovirus Early Region 1 Oncogenes.

Speiseder T, Hofmann-Sieber H, Rodríguez E, Schellenberg A, Akyüz N, Dierlamm J, Spruss T, Lange C, Dobner T.

J Virol. 2016 Dec 16;91(1). pii: e01782-16. doi: 10.1128/JVI.01782-16. Print 2017 Jan 1.

12.

Replication of Merkel cell polyomavirus induces reorganization of promyelocytic leukemia nuclear bodies.

Neumann F, Czech-Sioli M, Dobner T, Grundhoff A, Schreiner S, Fischer N.

J Gen Virol. 2016 Nov;97(11):2926-2938. doi: 10.1099/jgv.0.000593. Epub 2016 Aug 30.

PMID:
27580912
13.

Prevalence of hypoalbuminemia and nutritional issues in hospitalized elders.

Brock F, Bettinelli LA, Dobner T, Stobbe JC, Pomatti G, Telles CT.

Rev Lat Am Enfermagem. 2016 Aug 8;24:e2736. doi: 10.1590/1518-8345.0260.2736. English, Portuguese, Spanish.

14.

The Human Adenovirus Type 5 E4orf6/E1B55K E3 Ubiquitin Ligase Complex Enhances E1A Functional Activity.

Dallaire F, Schreiner S, Blair GE, Dobner T, Branton PE, Blanchette P.

mSphere. 2015 Nov 11;1(1). pii: e00015-15. doi: 10.1128/mSphere.00015-15. eCollection 2016 Jan-Feb.

15.

The Human Adenovirus Type 5 E4orf6/E1B55K E3 Ubiquitin Ligase Complex Can Mimic E1A Effects on E2F.

Dallaire F, Schreiner S, Blair GE, Dobner T, Branton PE, Blanchette P.

mSphere. 2015 Nov 11;1(1). pii: e00014-15. doi: 10.1128/mSphere.00014-15. eCollection 2016 Jan-Feb.

16.

[Downregulation of Human Adenovirus DNA Polymerase Gene by Modified siRNAs].

Nikitenko NA, Speiseder T, Chernolovskaya EL, Zenkova MA, Dobner T, Prassolov VS.

Mol Biol (Mosk). 2016 Jan-Feb;50(1):188-92. doi: 10.7868/S0026898416010158. Russian.

17.

Morphological, Biochemical, and Functional Study of Viral Replication Compartments Isolated from Adenovirus-Infected Cells.

Hidalgo P, Anzures L, Hernández-Mendoza A, Guerrero A, Wood CD, Valdés M, Dobner T, Gonzalez RA.

J Virol. 2016 Jan 13;90(7):3411-27. doi: 10.1128/JVI.00033-16.

18.

KAP1 Is a Host Restriction Factor That Promotes Human Adenovirus E1B-55K SUMO Modification.

Bürck C, Mund A, Berscheminski J, Kieweg L, Müncheberg S, Dobner T, Schreiner S.

J Virol. 2015 Nov 4;90(2):930-46. doi: 10.1128/JVI.01836-15. Print 2016 Jan 15.

19.

Regulation of Human Adenovirus Replication by RNA Interference.

Nikitenko NA, Speiseder T, Lam E, Rubtsov PM, Tonaeva KhD, Borzenok SA, Dobner T, Prassolov VS.

Acta Naturae. 2015 Jul-Sep;7(3):100-7.

20.

Sp100A is a tumor suppressor that activates p53-dependent transcription and counteracts E1A/E1B-55K-mediated transformation.

Berscheminski J, Brun J, Speiseder T, Wimmer P, Ip WH, Terzic M, Dobner T, Schreiner S.

Oncogene. 2016 Jun 16;35(24):3178-89. doi: 10.1038/onc.2015.378. Epub 2015 Oct 19.

PMID:
26477309
21.

Effective Apical Infection of Differentiated Human Bronchial Epithelial Cells and Induction of Proinflammatory Chemokines by the Highly Pneumotropic Human Adenovirus Type 14p1.

Lam E, Ramke M, Warnecke G, Schrepfer S, Kopfnagel V, Dobner T, Heim A.

PLoS One. 2015 Jul 13;10(7):e0131201. doi: 10.1371/journal.pone.0131201. eCollection 2015.

22.

Targeting species D adenoviruses replication to counteract the epidemic keratoconjunctivitis.

Nikitenko NA, Speiseder T, Groitl P, Spirin PV, Prokofjeva MM, Lebedev TD, Rubtsov PM, Lam E, Riecken K, Fehse B, Dobner T, Prassolov VS.

Biochimie. 2015 Jun;113:10-6. doi: 10.1016/j.biochi.2015.03.010. Epub 2015 Mar 19. Erratum in: Biochimie. 2015 Sep;116:166.

PMID:
25796214
23.

PML isoforms IV and V contribute to adenovirus-mediated oncogenic transformation by functionally inhibiting the tumor-suppressor p53.

Wimmer P, Berscheminski J, Blanchette P, Groitl P, Branton PE, Hay RT, Dobner T, Schreiner S.

Oncogene. 2016 Jan 7;35(1):69-82. doi: 10.1038/onc.2015.63. Epub 2015 Mar 16.

PMID:
25772236
24.

Adenovirus replaces mitotic checkpoint controls.

Turner RL, Groitl P, Dobner T, Ornelles DA.

J Virol. 2015 May;89(9):5083-96. doi: 10.1128/JVI.00213-15. Epub 2015 Feb 18.

25.

Influence of ND10 components on epigenetic determinants of early KSHV latency establishment.

Günther T, Schreiner S, Dobner T, Tessmer U, Grundhoff A.

PLoS Pathog. 2014 Jul 17;10(7):e1004274. doi: 10.1371/journal.ppat.1004274. eCollection 2014 Jul.

26.

Sp100 isoform-specific regulation of human adenovirus 5 gene expression.

Berscheminski J, Wimmer P, Brun J, Ip WH, Groitl P, Horlacher T, Jaffray E, Hay RT, Dobner T, Schreiner S.

J Virol. 2014 Jun;88(11):6076-92. doi: 10.1128/JVI.00469-14. Epub 2014 Mar 12.

27.

High-affinity Rb binding, p53 inhibition, subcellular localization, and transformation by wild-type or tumor-derived shortened Merkel cell polyomavirus large T antigens.

Borchert S, Czech-Sioli M, Neumann F, Schmidt C, Wimmer P, Dobner T, Grundhoff A, Fischer N.

J Virol. 2014 Mar;88(6):3144-60. doi: 10.1128/JVI.02916-13. Epub 2013 Dec 26.

28.

SPOC1-mediated antiviral host cell response is antagonized early in human adenovirus type 5 infection.

Schreiner S, Kinkley S, Bürck C, Mund A, Wimmer P, Schubert T, Groitl P, Will H, Dobner T.

PLoS Pathog. 2013;9(11):e1003775. doi: 10.1371/journal.ppat.1003775. Epub 2013 Nov 21.

29.

DNA virus replication compartments.

Schmid M, Speiseder T, Dobner T, Gonzalez RA.

J Virol. 2014 Feb;88(3):1404-20. doi: 10.1128/JVI.02046-13. Epub 2013 Nov 20. Review.

30.

Assessment of drug candidates for broad-spectrum antiviral therapy targeting cellular pyrimidine biosynthesis.

Marschall M, Niemann I, Kosulin K, Bootz A, Wagner S, Dobner T, Herz T, Kramer B, Leban J, Vitt D, Stamminger T, Hutterer C, Strobl S.

Antiviral Res. 2013 Dec;100(3):640-8. doi: 10.1016/j.antiviral.2013.10.003. Epub 2013 Oct 20.

PMID:
24149002
31.

Determination of the transforming activities of adenovirus oncogenes.

Speiseder T, Nevels M, Dobner T.

Methods Mol Biol. 2014;1089:105-15. doi: 10.1007/978-1-62703-679-5_8.

PMID:
24132481
32.

Presence of adenovirus species C in infiltrating lymphocytes of human sarcoma.

Kosulin K, Hoffmann F, Clauditz TS, Wilczak W, Dobner T.

PLoS One. 2013 May 6;8(5):e63646. doi: 10.1371/journal.pone.0063646. Print 2013.

33.

A ubiquitin-specific protease possesses a decisive role for adenovirus replication and oncogene-mediated transformation.

Ching W, Koyuncu E, Singh S, Arbelo-Roman C, Hartl B, Kremmer E, Speiseder T, Meier C, Dobner T.

PLoS Pathog. 2013 Mar;9(3):e1003273. doi: 10.1371/journal.ppat.1003273. Epub 2013 Mar 28.

34.

Specific phosphorylation of the PfRh2b invasion ligand of Plasmodium falciparum.

Engelberg K, Paul AS, Prinz B, Kono M, Ching W, Heincke D, Dobner T, Spielmann T, Duraisingh MT, Gilberger TW.

Biochem J. 2013 Jun 15;452(3):457-66. doi: 10.1042/BJ20121694.

35.

Role of E1B55K in E4orf6/E1B55K E3 ligase complexes formed by different human adenovirus serotypes.

Cheng CY, Gilson T, Wimmer P, Schreiner S, Ketner G, Dobner T, Branton PE, Blanchette P.

J Virol. 2013 Jun;87(11):6232-45. doi: 10.1128/JVI.00384-13. Epub 2013 Mar 27.

36.

Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes.

Schreiner S, Bürck C, Glass M, Groitl P, Wimmer P, Kinkley S, Mund A, Everett RD, Dobner T.

Nucleic Acids Res. 2013 Apr 1;41(6):3532-50. doi: 10.1093/nar/gkt064. Epub 2013 Feb 8.

37.

Expression of the coxsackie adenovirus receptor in neuroendocrine lung cancers and its implications for oncolytic adenoviral infection.

Wunder T, Schmid K, Wicklein D, Groitl P, Dobner T, Lange T, Anders M, Schumacher U.

Cancer Gene Ther. 2013 Jan;20(1):25-32. doi: 10.1038/cgt.2012.80. Epub 2012 Nov 30.

PMID:
23196273
38.

Amino acid exchanges in the putative nuclear export signal of adenovirus type 5 L4-100K severely reduce viral progeny due to effects on hexon biogenesis.

Koyuncu OO, Speiseder T, Dobner T, Schmid M.

J Virol. 2013 Feb;87(3):1893-8. doi: 10.1128/JVI.02061-12. Epub 2012 Nov 21.

39.

The adenoviral oncogene E1A-13S interacts with a specific isoform of the tumor suppressor PML to enhance viral transcription.

Berscheminski J, Groitl P, Dobner T, Wimmer P, Schreiner S.

J Virol. 2013 Jan;87(2):965-77. doi: 10.1128/JVI.02023-12. Epub 2012 Nov 7.

40.

Cross-talk between phosphorylation and SUMOylation regulates transforming activities of an adenoviral oncoprotein.

Wimmer P, Blanchette P, Schreiner S, Ching W, Groitl P, Berscheminski J, Branton PE, Will H, Dobner T.

Oncogene. 2013 Mar 28;32(13):1626-37. doi: 10.1038/onc.2012.187. Epub 2012 May 21.

PMID:
22614022
41.

Functional cooperation between human adenovirus type 5 early region 4, open reading frame 6 protein, and cellular homeobox protein HoxB7.

Müller D, Schreiner S, Schmid M, Groitl P, Winkler M, Dobner T.

J Virol. 2012 Aug;86(15):8296-308. doi: 10.1128/JVI.00222-12. Epub 2012 May 2.

42.

Transcriptional activation of the adenoviral genome is mediated by capsid protein VI.

Schreiner S, Martinez R, Groitl P, Rayne F, Vaillant R, Wimmer P, Bossis G, Sternsdorf T, Marcinowski L, Ruzsics Z, Dobner T, Wodrich H.

PLoS Pathog. 2012 Feb;8(2):e1002549. doi: 10.1371/journal.ppat.1002549. Epub 2012 Feb 23.

43.

Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair.

Polo SE, Blackford AN, Chapman JR, Baskcomb L, Gravel S, Rusch A, Thomas A, Blundred R, Smith P, Kzhyshkowska J, Dobner T, Taylor AM, Turnell AS, Stewart GS, Grand RJ, Jackson SP.

Mol Cell. 2012 Feb 24;45(4):505-16. doi: 10.1016/j.molcel.2011.12.035.

44.

Adenovirus degradation of cellular proteins.

Schreiner S, Wimmer P, Dobner T.

Future Microbiol. 2012 Feb;7(2):211-25. doi: 10.2217/fmb.11.153. Review.

PMID:
22324991
45.

Adenovirus E4orf3 targets transcriptional intermediary factor 1γ for proteasome-dependent degradation during infection.

Forrester NA, Patel RN, Speiseder T, Groitl P, Sedgwick GG, Shimwell NJ, Seed RI, Catnaigh PÓ, McCabe CJ, Stewart GS, Dobner T, Grand RJ, Martin A, Turnell AS.

J Virol. 2012 Mar;86(6):3167-79. doi: 10.1128/JVI.06583-11. Epub 2011 Dec 28.

46.

The human adenovirus type 5 E1B 55-kilodalton protein is phosphorylated by protein kinase CK2.

Ching W, Dobner T, Koyuncu E.

J Virol. 2012 Mar;86(5):2400-15. doi: 10.1128/JVI.06066-11. Epub 2011 Dec 21.

47.

CRM1-dependent transport supports cytoplasmic accumulation of adenoviral early transcripts.

Schmid M, Gonzalez RA, Dobner T.

J Virol. 2012 Feb;86(4):2282-92. doi: 10.1128/JVI.06275-11. Epub 2011 Dec 14.

48.

Human pathogens and the host cell SUMOylation system.

Wimmer P, Schreiner S, Dobner T.

J Virol. 2012 Jan;86(2):642-54. doi: 10.1128/JVI.06227-11. Epub 2011 Nov 9. Review.

49.

Intrinsic disorder in the common N-terminus of human adenovirus 5 E1B-55K and its related E1BN proteins indicated by studies on E1B-93R.

Sieber T, Scholz R, Spoerner M, Schumann F, Kalbitzer HR, Dobner T.

Virology. 2011 Sep 30;418(2):133-43. doi: 10.1016/j.virol.2011.07.012. Epub 2011 Aug 17.

50.

The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1.

Felle M, Joppien S, Németh A, Diermeier S, Thalhammer V, Dobner T, Kremmer E, Kappler R, Längst G.

Nucleic Acids Res. 2011 Oct;39(19):8355-65. doi: 10.1093/nar/gkr528. Epub 2011 Jul 10.

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