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Items: 23


CCNE1 amplification and centrosome number abnormality in serous tubal intraepithelial carcinoma: further evidence supporting its role as a precursor of ovarian high-grade serous carcinoma.

Kuhn E, Wang TL, Doberstein K, Bahadirli-Talbott A, Ayhan A, Sehdev AS, Drapkin R, Kurman RJ, Shih IeM.

Mod Pathol. 2016 Oct;29(10):1254-61. doi: 10.1038/modpathol.2016.101. Epub 2016 Jul 22.


Elafin: a double agent in breast and ovarian cancer.

Feng Y, Doberstein K, Drapkin R.

Oncoscience. 2015 Sep 17;2(10):793-4. eCollection 2015. No abstract available.


L1CAM in human cancer.

Altevogt P, Doberstein K, Fogel M.

Int J Cancer. 2016 Apr 1;138(7):1565-76. doi: 10.1002/ijc.29658. Epub 2015 Aug 25. Review.


L1CAM is expressed in triple-negative breast cancers and is inversely correlated with androgen receptor.

Doberstein K, Milde-Langosch K, Bretz NP, Schirmer U, Harari A, Witzel I, Ben-Arie A, Hubalek M, Müller-Holzner E, Reinold S, Zeimet AG, Altevogt P, Fogel M.

BMC Cancer. 2014 Dec 15;14:958. doi: 10.1186/1471-2407-14-958.


Paired box gene 8 (PAX8) expression is associated with sonic hedgehog (SHH)/wingless int (WNT) subtypes, desmoplastic histology and patient survival in human medulloblastomas.

Harter PN, Baumgarten P, Zinke J, Schilling K, Baader S, Hartmetz AK, Schittenhelm J, Beschorner R, Liebner S, Schulte D, Plate KH, Gutwein P, Korshunov A, Pfister SM, Jones DT, Doberstein K, Mittelbronn M.

Neuropathol Appl Neurobiol. 2015 Feb;41(2):165-79. doi: 10.1111/nan.12186.


Antibody therapy to human L1CAM in a transgenic mouse model blocks local tumor growth but induces EMT.

Doberstein K, Harter PN, Haberkorn U, Bretz NP, Arnold B, Carretero R, Moldenhauer G, Mittelbronn M, Altevogt P.

Int J Cancer. 2015 Mar 1;136(5):E326-39. doi: 10.1002/ijc.29222. Epub 2014 Sep 25.


miR-21-3p is a positive regulator of L1CAM in several human carcinomas.

Doberstein K, Bretz NP, Schirmer U, Fiegl H, Blaheta R, Breunig C, Müller-Holzner E, Reimer D, Zeimet AG, Altevogt P.

Cancer Lett. 2014 Nov 28;354(2):455-66. doi: 10.1016/j.canlet.2014.08.020. Epub 2014 Aug 19.


Lack of CD24 expression in mice reduces the number of leukocytes in the colon.

Bretz NP, Salnikov AV, Doberstein K, Garbi N, Kloess V, Joumaa S, Naumov I, Boon L, Moldenhauer G, Arber N, Altevogt P.

Immunol Lett. 2014 Sep;161(1):140-8. doi: 10.1016/j.imlet.2014.06.004. Epub 2014 Jun 20.


Role of miR-34a as a suppressor of L1CAM in endometrial carcinoma.

Schirmer U, Doberstein K, Rupp AK, Bretz NP, Wuttig D, Kiefel H, Breunig C, Fiegl H, Müller-Holzner E, Zeillinger R, Schuster E, Zeimet AG, Sültmann H, Altevogt P.

Oncotarget. 2014 Jan 30;5(2):462-72.


MicroRNA-145 targets the metalloprotease ADAM17 and is suppressed in renal cell carcinoma patients.

Doberstein K, Steinmeyer N, Hartmetz AK, Eberhardt W, Mittelbronn M, Harter PN, Juengel E, Blaheta R, Pfeilschifter J, Gutwein P.

Neoplasia. 2013 Feb;15(2):218-30.


The transcription factor PAX2 regulates ADAM10 expression in renal cell carcinoma.

Doberstein K, Pfeilschifter J, Gutwein P.

Carcinogenesis. 2011 Nov;32(11):1713-23. doi: 10.1093/carcin/bgr195. Epub 2011 Aug 30.


PAX2 regulates ADAM10 expression and mediates anchorage-independent cell growth of melanoma cells.

Lee SB, Doberstein K, Baumgarten P, Wieland A, Ungerer C, Bürger C, Hardt K, Boehncke WH, Pfeilschifter J, Mihic-Probst D, Mittelbronn M, Gutwein P.

PLoS One. 2011;6(8):e22312. doi: 10.1371/journal.pone.0022312. Epub 2011 Aug 18.


L1-CAM expression in ccRCC correlates with shorter patients survival times and confers chemoresistance in renal cell carcinoma cells.

Doberstein K, Wieland A, Lee SB, Blaheta RA, Wedel S, Moch H, Schraml P, Pfeilschifter J, Kristiansen G, Gutwein P.

Carcinogenesis. 2011 Mar;32(3):262-70. doi: 10.1093/carcin/bgq249. Epub 2010 Nov 19.


ADAM15 expression is downregulated in melanoma metastasis compared to primary melanoma.

Ungerer C, Doberstein K, Bürger C, Hardt K, Boehncke WH, Böhm B, Pfeilschifter J, Dummer R, Mihic-Probst D, Gutwein P.

Biochem Biophys Res Commun. 2010 Oct 22;401(3):363-9. doi: 10.1016/j.bbrc.2010.09.055. Epub 2010 Sep 17.


ADAM10 is expressed in human podocytes and found in urinary vesicles of patients with glomerular kidney diseases.

Gutwein P, Schramme A, Abdel-Bakky MS, Doberstein K, Hauser IA, Ludwig A, Altevogt P, Gauer S, Hillmann A, Weide T, Jespersen C, Eberhardt W, Pfeilschifter J.

J Biomed Sci. 2010 Jan 13;17:3. doi: 10.1186/1423-0127-17-3.


ADAM10 is upregulated in melanoma metastasis compared with primary melanoma.

Lee SB, Schramme A, Doberstein K, Dummer R, Abdel-Bakky MS, Keller S, Altevogt P, Oh ST, Reichrath J, Oxmann D, Pfeilschifter J, Mihic-Probst D, Gutwein P.

J Invest Dermatol. 2010 Mar;130(3):763-73. doi: 10.1038/jid.2009.335. Epub 2009 Oct 29.


CXCL16 is expressed in podocytes and acts as a scavenger receptor for oxidized low-density lipoprotein.

Gutwein P, Abdel-Bakky MS, Schramme A, Doberstein K, Kämpfer-Kolb N, Amann K, Hauser IA, Obermüller N, Bartel C, Abdel-Aziz AA, El Sayed el SM, Pfeilschifter J.

Am J Pathol. 2009 Jun;174(6):2061-72. doi: 10.2353/ajpath.2009.080960. Epub 2009 May 12.


CXCL16 and oxLDL are induced in the onset of diabetic nephropathy.

Gutwein P, Abdel-Bakky MS, Doberstein K, Schramme A, Beckmann J, Schaefer L, Amann K, Doller A, Kämpfer-Kolb N, Abdel-Aziz AA, El Sayed el SM, Pfeilschifter J.

J Cell Mol Med. 2009 Sep;13(9B):3809-25. doi: 10.1111/j.1582-4934.2009.00761.x. Epub 2009 May 1.


Downregulation of junctional adhesion molecule-A is involved in the progression of clear cell renal cell carcinoma.

Gutwein P, Schramme A, Voss B, Abdel-Bakky MS, Doberstein K, Ludwig A, Altevogt P, Hansmann ML, Moch H, Kristiansen G, Pfeilschifter J.

Biochem Biophys Res Commun. 2009 Mar 6;380(2):387-91. doi: 10.1016/j.bbrc.2009.01.100. Epub 2009 Jan 23.


Interaction of the replication proteins and the capsid protein of porcine circovirus type 1 and 2 with host proteins.

Finsterbusch T, Steinfeldt T, Doberstein K, Rödner C, Mankertz A.

Virology. 2009 Mar 30;386(1):122-31. doi: 10.1016/j.virol.2008.12.039.


Tumoural CXCL16 expression is a novel prognostic marker of longer survival times in renal cell cancer patients.

Gutwein P, Schramme A, Sinke N, Abdel-Bakky MS, Voss B, Obermüller N, Doberstein K, Koziolek M, Fritzsche F, Johannsen M, Jung K, Schaider H, Altevogt P, Ludwig A, Pfeilschifter J, Kristiansen G.

Eur J Cancer. 2009 Feb;45(3):478-89. doi: 10.1016/j.ejca.2008.10.023. Epub 2008 Dec 11.


Gene expression of the human Torque Teno Virus isolate P/1C1.

Mueller B, Maerz A, Doberstein K, Finsterbusch T, Mankertz A.

Virology. 2008 Nov 10;381(1):36-45. doi: 10.1016/j.virol.2008.08.017. Epub 2008 Sep 17.


Novel intra-tissue perfusion system for culturing thick liver tissue.

Khong YM, Zhang J, Zhou S, Cheung C, Doberstein K, Samper V, Yu H.

Tissue Eng. 2007 Sep;13(9):2345-56.


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