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Items: 9


p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication.

Cannell IG, Kong YW, Johnston SJ, Chen ML, Collins HM, Dobbyn HC, Elia A, Kress TR, Dickens M, Clemens MJ, Heery DM, Gaestel M, Eilers M, Willis AE, Bushell M.

Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5375-80. doi: 10.1073/pnas.0910015107. Epub 2010 Mar 8.


Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes.

Powley IR, Kondrashov A, Young LA, Dobbyn HC, Hill K, Cannell IG, Stoneley M, Kong YW, Cotes JA, Smith GC, Wek R, Hayes C, Gant TW, Spriggs KA, Bushell M, Willis AE.

Genes Dev. 2009 May 15;23(10):1207-20. doi: 10.1101/gad.516509.


The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene.

Kong YW, Cannell IG, de Moor CH, Hill K, Garside PG, Hamilton TL, Meijer HA, Dobbyn HC, Stoneley M, Spriggs KA, Willis AE, Bushell M.

Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):8866-71. doi: 10.1073/pnas.0800650105. Epub 2008 Jun 25.


Identification of internal ribosome entry segment (IRES)-trans-acting factors for the Myc family of IRESs.

Cobbold LC, Spriggs KA, Haines SJ, Dobbyn HC, Hayes C, de Moor CH, Lilley KS, Bushell M, Willis AE.

Mol Cell Biol. 2008 Jan;28(1):40-9. Epub 2007 Oct 29.


Regulation of BAG-1 IRES-mediated translation following chemotoxic stress.

Dobbyn HC, Hill K, Hamilton TL, Spriggs KA, Pickering BM, Coldwell MJ, de Moor CH, Bushell M, Willis AE.

Oncogene. 2008 Feb 14;27(8):1167-74. Epub 2007 Aug 13.


Analysis of pre-mRNA and pre-rRNA processing factor Snu13p structure and mutants.

Dobbyn HC, McEwan PA, Krause A, Novak-Frazer L, Bella J, O'Keefe RT.

Biochem Biophys Res Commun. 2007 Sep 7;360(4):857-62. Epub 2007 Jul 9.


Polypyrimidine tract binding protein regulates IRES-mediated gene expression during apoptosis.

Bushell M, Stoneley M, Kong YW, Hamilton TL, Spriggs KA, Dobbyn HC, Qin X, Sarnow P, Willis AE.

Mol Cell. 2006 Aug 4;23(3):401-12.


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