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134 results

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Page 1
LncRNA DNAJC3-AS1 Promotes Hepatocellular Carcinoma (HCC) Progression via Sponging Premature miR-27b.
Fu C, Li J, Li P, Cheng D. Fu C, et al. Cancer Manag Res. 2021 Nov 15;13:8575-8583. doi: 10.2147/CMAR.S321111. eCollection 2021. Cancer Manag Res. 2021. PMID: 34815712 Free PMC article.
PURPOSE: Long non-coding RNA (lncRNA) DNAJC3 antisense RNA 1 (head to head) (DNAJC3-AS1) plays a key role in the progression of several cancers. ...Subcellular analysis of DNAJC3-AS1 was explored by subcellular fractionation assay. DNAJC3-AS1 overexpre …
PURPOSE: Long non-coding RNA (lncRNA) DNAJC3 antisense RNA 1 (head to head) (DNAJC3-AS1) plays a key role in the progression o …
LncRNA DNAJC3-AS1 promotes the biological functions of papillary thyroid carcinoma via regulating the microRNA-27a-3p/CCBE1 axis.
Ni T, Li Y, Guo D, Tan L, Xiao Z, Shi Y. Ni T, et al. Cell Biol Int. 2023 Mar;47(3):539-547. doi: 10.1002/cbin.11946. Epub 2022 Dec 30. Cell Biol Int. 2023. PMID: 36583660
Long noncoding RNA DNAJC3-AS1 (lncRNA DNAJC3-AS1) has been probed in many studies, while the regulatory mechanism of DNAJC3-AS1 on papillary thyroid carcinoma (PTC) via regulating microRNA (miR)-27a-3p remains inadequate. ...DNAJC3-AS1 bound to miR-27a …
Long noncoding RNA DNAJC3-AS1 (lncRNA DNAJC3-AS1) has been probed in many studies, while the regulatory mechanism of DNAJC3 …
Biallelic DNAJC3 variants in a neuroendocrine developmental disorder with insulin dysregulation.
Ocansey S, Pullen D, Atkinson P, Clarke A, Hadonou M, Crosby C, Short J, Lloyd IC, Smedley D, Assunta A, Shah P, McEntagart M; Genomics England Research Consortium. Ocansey S, et al. Clin Dysmorphol. 2022 Jan 1;31(1):11-17. doi: 10.1097/MCD.0000000000000397. Clin Dysmorphol. 2022. PMID: 34654017
DNAJC3, a co-chaperone of BiP, is a member of the heat shock protein family. ...This report confirms DNAJC3 as a cause of syndromic congenital hyperinsulinaemic hypoglycaemia. ...
DNAJC3, a co-chaperone of BiP, is a member of the heat shock protein family. ...This report confirms DNAJC3 as a cause of synd …
MiR-140 Targets lncRNA DNAJC3-AS1 to Suppress Cell Proliferation in Acute Myeloid Leukemia.
Li H, Bi K, Feng S, Wang Y, Zhu C. Li H, et al. Mediterr J Hematol Infect Dis. 2022 Jan 1;14(1):e2022005. doi: 10.4084/MJHID.2022.005. eCollection 2022. Mediterr J Hematol Infect Dis. 2022. PMID: 35070212 Free PMC article.
This study aimed to explore the role of miR-140 and DNAJC3-AS1 in AML. METHODS: The expression of DNAJC3-AS1 and miR-140 were detected by RT-qPCR. ...DNAJC3-AS1 was detected in nuclear and cytoplasm samples and direct interaction between DNAJC3-AS1 and …
This study aimed to explore the role of miR-140 and DNAJC3-AS1 in AML. METHODS: The expression of DNAJC3-AS1 and miR-140 were …
DNAJC3 deficiency induces beta-cell mitochondrial apoptosis and causes syndromic young-onset diabetes.
Lytrivi M, Senée V, Salpea P, Fantuzzi F, Philippi A, Abdulkarim B, Sawatani T, Marín-Cañas S, Pachera N, Degavre A, Singh P, Derbois C, Lechner D, Ladrière L, Igoillo-Esteve M, Cosentino C, Marselli L, Deleuze JF, Marchetti P, Eizirik DL, Nicolino M, Chaussenot A, Julier C, Cnop M. Lytrivi M, et al. Eur J Endocrinol. 2021 Mar;184(3):455-468. doi: 10.1530/EJE-20-0636. Eur J Endocrinol. 2021. PMID: 33486469
Dnajc3 deficiency in mice causes pancreatic beta-cell loss and diabetes. ...They were heterozygous compound and homozygous for novel loss-of-function mutations in DNAJC3. DNAJC3 silencing did not impair insulin content or secretion. ...
Dnajc3 deficiency in mice causes pancreatic beta-cell loss and diabetes. ...They were heterozygous compound and homozygous for novel …
Reduced DNAJC3 Expression Affects Protein Translocation across the ER Membrane and Attenuates the Down-Modulating Effect of the Translocation Inhibitor Cyclotriazadisulfonamide.
Pauwels E, Provinciael B, Camps A, Hartmann E, Vermeire K. Pauwels E, et al. Int J Mol Sci. 2022 Jan 6;23(2):584. doi: 10.3390/ijms23020584. Int J Mol Sci. 2022. PMID: 35054769 Free PMC article.
In this study, we investigated the impact of altered DNAJC3 protein levels on the inhibitory activity of CADA. By comparing WT DNAJC3 with a CADA-resistant DNAJC3 mutant, we observed the enhanced sensitivity of human CD4, PTK7 and ERLEC1 for CADA when DNAJ …
In this study, we investigated the impact of altered DNAJC3 protein levels on the inhibitory activity of CADA. By comparing WT DNA …
LncRNA DNAJC3-AS1 functions as oncogene in renal cell carcinoma via regulation of the miR-27a-3p/PRDM14 axis.
Na XY, Hu XQ, Zhao Y, Hu CH, Shang XS. Na XY, et al. Eur Rev Med Pharmacol Sci. 2021 Feb;25(3):1291-1301. doi: 10.26355/eurrev_202102_24833. Eur Rev Med Pharmacol Sci. 2021. PMID: 33629299 Free article.
The proliferation, migration, invasion and apoptosis of ccRCC cells were measured after silencing DNAJC3-AS1. The interaction between DNAJC3-AS1, miR-27a-3p and PRDM14 was identified by Dual-Luciferase reporter assay. ...Downregulation of DNAJC3-AS1 also led …
The proliferation, migration, invasion and apoptosis of ccRCC cells were measured after silencing DNAJC3-AS1. The interaction between …
LncRNA DNAJC3-AS1 Regulates Fatty Acid Synthase via the EGFR Pathway to Promote the Progression of Colorectal Cancer.
Tang Y, Tang R, Tang M, Huang P, Liao Z, Zhou J, Zhou L, Su M, Chen P, Jiang J, Hu Y, Zhou Y, Liao Q, Zeng Z, Xiong W, Chen J, Nie S. Tang Y, et al. Front Oncol. 2021 Feb 2;10:604534. doi: 10.3389/fonc.2020.604534. eCollection 2020. Front Oncol. 2021. PMID: 33604287 Free PMC article.
By constructing a differential lncRNA expression profile, we screened gene chips and found that DNAJC3-AS1 was highly expressed in CRC tissues and was associated with poor prognosis in patients with CRC. ...Therefore, DNAJC3-AS1 may be a new target for the diagnosis …
By constructing a differential lncRNA expression profile, we screened gene chips and found that DNAJC3-AS1 was highly expressed in CR …
Down-regulation of lncRNA DNAJC3-AS1 inhibits colon cancer via regulating miR-214-3p/LIVIN axis.
Han B, Ge Y, Cui J, Liu B. Han B, et al. Bioengineered. 2020 Dec;11(1):524-535. doi: 10.1080/21655979.2020.1757224. Bioengineered. 2020. PMID: 32352854 Free PMC article.
Moreover, miR-214-3p can bind to DNAJC3-AS1, and knockdown of DNAJC3-AS1 increased miR-214-3p expression in colon cancer cells. ...These findings suggested that DNAJC3-AS1 may promote colon cancer progression by regulating the miR-214-3p/LIVIN axis. ...
Moreover, miR-214-3p can bind to DNAJC3-AS1, and knockdown of DNAJC3-AS1 increased miR-214-3p expression in colon cancer cells …
Long noncoding RNA DNAJC3-AS1 promotes osteosarcoma progression via its sense-cognate gene DNAJC3.
Liang R, Liu Z, Chen Z, Yang Y, Li Y, Cui Z, Chen A, Long Z, Chen J, Lu J, Huang B, Li Q. Liang R, et al. Cancer Med. 2019 Feb;8(2):761-772. doi: 10.1002/cam4.1955. Epub 2019 Jan 16. Cancer Med. 2019. PMID: 30652414 Free PMC article.
These effects of DNAJC3-AS1 were reversed by down-regulation of its sense-cognate gene DNAJC3. Thus, DNAJC3-AS1 promotes osteosarcoma development and progression by regulating DNAJC3 and might be a biomarker and therapeutic target for osteosarcoma....
These effects of DNAJC3-AS1 were reversed by down-regulation of its sense-cognate gene DNAJC3. Thus, DNAJC3-AS1 promote …
134 results