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Items: 1 to 50 of 232

1.

Niche-Specific Factors Dynamically Regulate Sebaceous Gland Stem Cells in the Skin.

Veniaminova NA, Grachtchouk M, Doane OJ, Peterson JK, Quigley DA, Lull MV, Pyrozhenko DV, Nair RR, Patrick MT, Balmain A, Dlugosz AA, Tsoi LC, Wong SY.

Dev Cell. 2019 Nov 4;51(3):326-340.e4. doi: 10.1016/j.devcel.2019.08.015. Epub 2019 Sep 26.

PMID:
31564613
2.

Sleep quality and daytime sleepiness among Polish anaesthesiologists and intensivists.

Krzych ŁJ, Piekiełko P, Baca A, Długosz A, Liberski P, Jaworski T, Kasperczyk J.

J Crit Care. 2019 Oct;53:87-90. doi: 10.1016/j.jcrc.2019.06.005. Epub 2019 Jun 4.

PMID:
31202163
3.

Osteogenic differentiation of human adipose-derived stem cells in 3D conditions - comparison of spheroids and polystyrene scaffolds.

Rumiński S, Kalaszczyńska I, Długosz A, Lewandowska-Szumieł M.

Eur Cell Mater. 2019 May 17;37:382-401. doi: 10.22203/eCM.v037a23.

4.

The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity.

Billi AC, Gharaee-Kermani M, Fullmer J, Tsoi LC, Hill BD, Gruszka D, Ludwig J, Xing X, Estadt S, Wolf SJ, Rizvi SM, Berthier CC, Hodgin JB, Beamer MA, Sarkar MK, Liang Y, Uppala R, Shao S, Zeng C, Harms PW, Verhaegen ME, Voorhees JJ, Wen F, Ward NL, Dlugosz AA, Kahlenberg JM, Gudjonsson JE.

JCI Insight. 2019 Apr 18;4(8). pii: 127291. doi: 10.1172/jci.insight.127291. eCollection 2019 Apr 18.

5.

Characterizing the Therapeutic Potential of a Potent BET Degrader in Merkel Cell Carcinoma.

Choi JE, Verhaegen ME, Yazdani S, Malik R, Harms PW, Mangelberger D, Tien J, Cao X, Wang Y, Cieślik M, Gurkan J, Yazdani M, Jing X, Juckette K, Su F, Wang R, Zhou B, Apel IJ, Wang S, Dlugosz AA, Chinnaiyan AM.

Neoplasia. 2019 Mar;21(3):322-330. doi: 10.1016/j.neo.2019.01.003. Epub 2019 Feb 21.

6.

Insight into the Etiology of Undifferentiated Soft Tissue Sarcomas from a Novel Mouse Model.

Fleming JT, Brignola E, Chen L, Guo Y, Zhao S, Wang Q, Li B, Correa H, Ermilov AN, Dlugosz AA, Chiang C.

Mol Cancer Res. 2019 May;17(5):1024-1035. doi: 10.1158/1541-7786.MCR-18-0117. Epub 2019 Jan 25.

7.

Hedgehog signaling induces PD-L1 expression and tumor cell proliferation in gastric cancer.

Chakrabarti J, Holokai L, Syu L, Steele NG, Chang J, Wang J, Ahmed S, Dlugosz A, Zavros Y.

Oncotarget. 2018 Dec 21;9(100):37439-37457. doi: 10.18632/oncotarget.26473. eCollection 2018 Dec 21.

8.

Preliminary Evaluation of the Diagnostic Usefulness of Uroplakin 2 with an Assessment of the Antioxidant Potential of Patients with Bladder Cancer.

Matuszewski M, Szymańska B, Długosz A, Małkiewicz B, Dembowski J, Piwowar A.

Biomed Res Int. 2018 Nov 29;2018:8693297. doi: 10.1155/2018/8693297. eCollection 2018.

9.

Reproducibility of a Questionnaire for Dietary Habits, Lifestyle and Nutrition Knowledge Assessment (KomPAN) in Polish Adolescents and Adults.

Kowalkowska J, Wadolowska L, Czarnocinska J, Czlapka-Matyasik M, Galinski G, Jezewska-Zychowicz M, Bronkowska M, Dlugosz A, Loboda D, Wyka J.

Nutrients. 2018 Dec 1;10(12). pii: E1845. doi: 10.3390/nu10121845.

10.

Low molecular weight proteins and enzymes in the urine of patients with bladder cancer - a pilot study.

Marchewka Z, Szymańska B, Dembowski J, Długosz A, Piwowar A.

Cent European J Urol. 2018;71(3):280-286. doi: 10.5173/ceju.2018.1661. Epub 2018 Sep 22.

11.

Massive air embolism as a complication of upper gastrointestinal endoscopy: A case report illustrating a stroke mimic, literature review, and suggested management.

Kjellberg A, Nyström H, Söderberg M, Dlugosz A, Jörnvall H, Steinberg A.

Clin Case Rep. 2018 Aug 8;6(9):1862-1867. doi: 10.1002/ccr3.1725. eCollection 2018 Sep.

12.

Involvement of a coumarin analog AD-013 in the DNA damage response pathways in MCF-7 cells.

Długosz A, Drogosz J, Deredas D, Janecki T, Janecka A.

Mol Biol Rep. 2018 Oct;45(5):1187-1195. doi: 10.1007/s11033-018-4271-z. Epub 2018 Aug 7.

13.

Uroplakin IIIa Is a Marker in Bladder Cancer but Seems Not to Reflect Chemical Carcinogenesis.

Szymańska B, Matuszewski M, Dembowski J, Zdrojowy R, Długosz A.

Biomed Res Int. 2018 Jul 5;2018:8315410. doi: 10.1155/2018/8315410. eCollection 2018.

14.

Circulating Cell-Free miR-375 as Surrogate Marker of Tumor Burden in Merkel Cell Carcinoma.

Fan K, Ritter C, Nghiem P, Blom A, Verhaegen ME, Dlugosz A, Ødum N, Woetmann A, Tothill RW, Hicks RJ, Sand M, Schrama D, Schadendorf D, Ugurel S, Becker JC.

Clin Cancer Res. 2018 Dec 1;24(23):5873-5882. doi: 10.1158/1078-0432.CCR-18-1184. Epub 2018 Jul 30.

PMID:
30061360
15.

Mouse-Derived Gastric Organoid and Immune Cell Co-culture for the Study of the Tumor Microenvironment.

Chakrabarti J, Holokai L, Syu L, Steele N, Chang J, Dlugosz A, Zavros Y.

Methods Mol Biol. 2018;1817:157-168. doi: 10.1007/978-1-4939-8600-2_16.

PMID:
29959712
16.

Synthesis of 3-Methylidene-1-tosyl-2,3-dihydroquinolin-4(1H)-ones as Potent Cytotoxic Agents.

Koszuk J, Bartosik T, Wojciechowski J, Wolf WM, Janecka A, Drogosz J, Długosz A, Krajewska U, Mirowski M, Janecki T.

Chem Biodivers. 2018 Sep;15(9):e1800242. doi: 10.1002/cbdv.201800242. Epub 2018 Aug 8.

PMID:
29935105
17.

Involvement of α-methylene-γ- and δ-lactones in the suppression of multidrug resistance in MCF-7 cells.

Długosz A, Gach-Janczak K, Szymański J, Deredas D, Janecki T, Janecka A.

Pharmacol Rep. 2018 Aug;70(4):631-638. doi: 10.1016/j.pharep.2018.01.002. Epub 2018 Jan 10.

PMID:
29886368
18.

Female-Specific Association Between Variants on Chromosome 9 and Self-Reported Diagnosis of Irritable Bowel Syndrome.

Bonfiglio F, Zheng T, Garcia-Etxebarria K, Hadizadeh F, Bujanda L, Bresso F, Agreus L, Andreasson A, Dlugosz A, Lindberg G, Schmidt PT, Karling P, Ohlsson B, Simren M, Walter S, Nardone G, Cuomo R, Usai-Satta P, Galeazzi F, Neri M, Portincasa P, Bellini M, Barbara G, Latiano A, Hübenthal M, Thijs V, Netea MG, Jonkers D, Chang L, Mayer EA, Wouters MM, Boeckxstaens G, Camilleri M, Franke A, Zhernakova A, D'Amato M.

Gastroenterology. 2018 Jul;155(1):168-179. doi: 10.1053/j.gastro.2018.03.064. Epub 2018 Apr 5.

19.

THE ESTROGENS / CHROMIUM INTERACTION IN THE NITRIC OXIDE GENERATION.

Sawicka E, Piwowar A, Musiala T, Dlugosz A.

Acta Pol Pharm. 2017 May;74(3):785-791.

20.

Increased Prevalence of Rare Sucrase-isomaltase Pathogenic Variants in Irritable Bowel Syndrome Patients.

Garcia-Etxebarria K, Zheng T, Bonfiglio F, Bujanda L, Dlugosz A, Lindberg G, Schmidt PT, Karling P, Ohlsson B, Simren M, Walter S, Nardone G, Cuomo R, Usai-Satta P, Galeazzi F, Neri M, Portincasa P, Bellini M, Barbara G, Jonkers D, Eswaran S, Chey WD, Kashyap P, Chang L, Mayer EA, Wouters MM, Boeckxstaens G, Camilleri M, Franke A, D'Amato M.

Clin Gastroenterol Hepatol. 2018 Oct;16(10):1673-1676. doi: 10.1016/j.cgh.2018.01.047. Epub 2018 Feb 21.

21.

Tumor Architecture and Notch Signaling Modulate Drug Response in Basal Cell Carcinoma.

Eberl M, Mangelberger D, Swanson JB, Verhaegen ME, Harms PW, Frohm ML, Dlugosz AA, Wong SY.

Cancer Cell. 2018 Feb 12;33(2):229-243.e4. doi: 10.1016/j.ccell.2017.12.015. Epub 2018 Jan 27.

22.

Evaluation of NMP22 in bladder cancer patients sensitive to environmental toxins.

Szymańska B, Pawlik KJ, Sawicka E, Dembowski J, Kowal P, Zdrojowy R, Długosz A.

Adv Clin Exp Med. 2017 Oct;26(7):1069-1075. doi: 10.17219/acem/63156.

23.

Recovery of taste organs and sensory function after severe loss from Hedgehog/Smoothened inhibition with cancer drug sonidegib.

Kumari A, Ermilov AN, Grachtchouk M, Dlugosz AA, Allen BL, Bradley RM, Mistretta CM.

Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):E10369-E10378. doi: 10.1073/pnas.1712881114. Epub 2017 Nov 13.

24.

miR-16 and miR-103 impact 5-HT4 receptor signalling and correlate with symptom profile in irritable bowel syndrome.

Wohlfarth C, Schmitteckert S, Härtle JD, Houghton LA, Dweep H, Fortea M, Assadi G, Braun A, Mederer T, Pöhner S, Becker PP, Fischer C, Granzow M, Mönnikes H, Mayer EA, Sayuk G, Boeckxstaens G, Wouters MM, Simrén M, Lindberg G, Ohlsson B, Schmidt PT, Dlugosz A, Agreus L, Andreasson A, D'Amato M, Burwinkel B, Bermejo JL, Röth R, Lasitschka F, Vicario M, Metzger M, Santos J, Rappold GA, Martinez C, Niesler B.

Sci Rep. 2017 Oct 31;7(1):14680. doi: 10.1038/s41598-017-13982-0.

25.

Functional polymorphism of the renalase gene is associated with cardiac hypertrophy in female patients with aortic stenosis.

Orlowska-Baranowska E, Gadomska Vel Betka L, Gora J, Baranowski R, Pedzich-Placha E, Zakrzewski D, Dlugosz A, Kossowska H, Zebrowska A, Zakoscielna E, Janiszewska A, Hryniewiecki T, Gaciong Z, Placha G.

PLoS One. 2017 Oct 24;12(10):e0186729. doi: 10.1371/journal.pone.0186729. eCollection 2017.

26.

Anticancer Properties of a New Hybrid Analog AD-013 Combining a Coumarin Scaffold with an α-methylene-δ-lactone Motif.

Dlugosz A, Gach-Janczak K, Szymanski J, Deredas D, Krawczyk H, Janecki T, Janecka A.

Anticancer Agents Med Chem. 2018;18(3):450-457. doi: 10.2174/1871520617666170921123654.

PMID:
28933263
27.

The Diagnostic Value of Nuclear Matrix Proteins in Bladder Cancer in the Aspect of Environmental Risk from Carcinogens.

Szymańska B, Sawicka E, Guzik A, Zdrojowy R, Długosz A.

Biomed Res Int. 2017;2017:9643139. doi: 10.1155/2017/9643139. Epub 2017 Aug 8.

28.

Indoleamine 2,3-Dioxygenase 1, Increased in Human Gastric Pre-Neoplasia, Promotes Inflammation and Metaplasia in Mice and Is Associated With Type II Hypersensitivity/Autoimmunity.

El-Zaatari M, Bass AJ, Bowlby R, Zhang M, Syu LJ, Yang Y, Grasberger H, Shreiner A, Tan B, Bishu S, Leung WK, Todisco A, Kamada N, Cascalho M, Dlugosz AA, Kao JY.

Gastroenterology. 2018 Jan;154(1):140-153.e17. doi: 10.1053/j.gastro.2017.09.002. Epub 2017 Sep 11.

29.

The role of the BLCA-4 nuclear matrix protein in bladder cancer.

Szymańska B, Długosz A.

Postepy Hig Med Dosw (Online). 2017 Aug 13;71(1):681-689. Review.

30.

The role of 17β-estradiol metabolites in chromium-induced oxidative stress.

Sawicka E, Długosz A.

Adv Clin Exp Med. 2017 Mar-Apr;26(2):215-221. doi: 10.17219/acem/62217.

31.

Glutathione S - transferases class Pi and Mi and their significance in oncology.

Marchewka Z, Piwowar A, Ruzik S, Długosz A.

Postepy Hig Med Dosw (Online). 2017 Jun 19;71(0):541-550. Review.

PMID:
28665283
32.

Merkel Cell Polyomavirus Small T Antigen Initiates Merkel Cell Carcinoma-like Tumor Development in Mice.

Verhaegen ME, Mangelberger D, Harms PW, Eberl M, Wilbert DM, Meireles J, Bichakjian CK, Saunders TL, Wong SY, Dlugosz AA.

Cancer Res. 2017 Jun 15;77(12):3151-3157. doi: 10.1158/0008-5472.CAN-17-0035. Epub 2017 May 16.

33.

New Chiral Ebselen Analogues with Antioxidant and Cytotoxic Potential.

Pacuła AJ, Kaczor KB, Antosiewicz J, Janecka A, Długosz A, Janecki T, Wojtczak A, Ścianowski J.

Molecules. 2017 Mar 20;22(3). pii: E492. doi: 10.3390/molecules22030492.

34.

Cilia-dependent GLI processing in neural crest cells is required for tongue development.

Millington G, Elliott KH, Chang YT, Chang CF, Dlugosz A, Brugmann SA.

Dev Biol. 2017 Apr 15;424(2):124-137. doi: 10.1016/j.ydbio.2017.02.021. Epub 2017 Mar 9.

35.

Synthesis of 4,4-Disubstituted 3-Methylidenechroman-2-ones as Potent Anticancer Agents.

Jakubowski R, Pomorska DK, Długosz A, Janecka A, Krajewska U, Różalski M, Mirowski M, Bartosik T, Janecki T.

ChemMedChem. 2017 Apr 20;12(8):599-605. doi: 10.1002/cmdc.201700080. Epub 2017 Mar 22.

PMID:
28258688
36.

Increased Expression of Toll-Like Receptors 4, 5, and 9 in Small Bowel Mucosa from Patients with Irritable Bowel Syndrome.

Dlugosz A, Zakikhany K, Acevedo N, D'Amato M, Lindberg G.

Biomed Res Int. 2017;2017:9624702. doi: 10.1155/2017/9624702. Epub 2017 Jan 29.

37.

Loss of Pin1 Suppresses Hedgehog-Driven Medulloblastoma Tumorigenesis.

Xu T, Zhang H, Park SS, Venneti S, Kuick R, Ha K, Michael LE, Santi M, Uchida C, Uchida T, Srinivasan A, Olson JM, Dlugosz AA, Camelo-Piragua S, Rual JF.

Neoplasia. 2017 Mar;19(3):216-225. doi: 10.1016/j.neo.2017.01.002. Epub 2017 Feb 3.

38.

New glutathione peroxidase mimetics-Insights into antioxidant and cytotoxic activity.

Pacuła AJ, Kaczor KB, Wojtowicz A, Antosiewicz J, Janecka A, Długosz A, Janecki T, Ścianowski J.

Bioorg Med Chem. 2017 Jan 1;25(1):126-131. doi: 10.1016/j.bmc.2016.10.018. Epub 2016 Oct 18.

PMID:
28029457
39.

Novobiocin Analogs as Potential Anticancer Agents.

Dlugosz A, Janecka A.

Mini Rev Med Chem. 2017;17(9):728-733. doi: 10.2174/1389557516666161223155525. Review.

PMID:
28019639
40.

TRPM8 polymorphisms associated with increased risk of IBS-C and IBS-M.

Henström M, Hadizadeh F, Beyder A, Bonfiglio F, Zheng T, Assadi G, Rafter J, Bujanda L, Agreus L, Andreasson A, Dlugosz A, Lindberg G, Schmidt PT, Karling P, Ohlsson B, Talley NJ, Simren M, Walter S, Wouters M, Farrugia G, D'Amato M.

Gut. 2017 Sep;66(9):1725-1727. doi: 10.1136/gutjnl-2016-313346. Epub 2016 Dec 14. No abstract available.

41.

Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling.

Ermilov AN, Kumari A, Li L, Joiner AM, Grachtchouk MA, Allen BL, Dlugosz AA, Mistretta CM.

PLoS Genet. 2016 Nov 28;12(11):e1006442. doi: 10.1371/journal.pgen.1006442. eCollection 2016 Nov.

42.

Functional variants in the sucrase-isomaltase gene associate with increased risk of irritable bowel syndrome.

Henström M, Diekmann L, Bonfiglio F, Hadizadeh F, Kuech EM, von Köckritz-Blickwede M, Thingholm LB, Zheng T, Assadi G, Dierks C, Heine M, Philipp U, Distl O, Money ME, Belheouane M, Heinsen FA, Rafter J, Nardone G, Cuomo R, Usai-Satta P, Galeazzi F, Neri M, Walter S, Simrén M, Karling P, Ohlsson B, Schmidt PT, Lindberg G, Dlugosz A, Agreus L, Andreasson A, Mayer E, Baines JF, Engstrand L, Portincasa P, Bellini M, Stanghellini V, Barbara G, Chang L, Camilleri M, Franke A, Naim HY, D'Amato M.

Gut. 2018 Feb;67(2):263-270. doi: 10.1136/gutjnl-2016-312456. Epub 2016 Nov 21.

43.

Anticancer activity of new molecular hybrids combining 1,4-naphthalenedione motif with phosphonic acid moiety in hepatocellular carcinoma HepG2 cells.

Długosz A, Gach K, Szymański J, Modranka J, Janecki T, Janecka A.

Acta Biochim Pol. 2017;64(1):41-48. doi: 10.18388/abp.2016_1264. Epub 2016 Nov 4.

44.

ABC Transporters in the Development of Multidrug Resistance in Cancer Therapy.

Dlugosz A, Janecka A.

Curr Pharm Des. 2016;22(30):4705-4716. Review.

PMID:
26932159
45.

Prevalence of Eosinophilic Esophagitis and Lymphocytic Esophagitis in Adults with Esophageal Food Bolus Impaction.

Truskaite K, Dlugosz A.

Gastroenterol Res Pract. 2016;2016:9303858. doi: 10.1155/2016/9303858. Epub 2016 Jul 28.

46.

Diagnostic yield of endomicroscopy for dysplasia in primary sclerosing cholangitis associated inflammatory bowel disease: a feasibility study.

Dlugosz A, Barakat AM, Björkström NK, Öst Å, Bergquist A.

Endosc Int Open. 2016 Aug;4(8):E901-11. doi: 10.1055/s-0042-111203. Epub 2016 Aug 5.

47.

Reciprocal interplay between thyroid hormone and microRNA-21 regulates hedgehog pathway-driven skin tumorigenesis.

Di Girolamo D, Ambrosio R, De Stefano MA, Mancino G, Porcelli T, Luongo C, Di Cicco E, Scalia G, Vecchio LD, Colao A, Dlugosz AA, Missero C, Salvatore D, Dentice M.

J Clin Invest. 2016 Jun 1;126(6):2308-20. doi: 10.1172/JCI84465. Epub 2016 May 9.

48.

Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways.

Syu LJ, Zhao X, Zhang Y, Grachtchouk M, Demitrack E, Ermilov A, Wilbert DM, Zheng X, Kaatz A, Greenson JK, Gumucio DL, Merchant JL, di Magliano MP, Samuelson LC, Dlugosz AA.

Oncotarget. 2016 Mar 1;7(9):10255-70. doi: 10.18632/oncotarget.7182.

49.

Next generation sequencing of Cytokeratin 20-negative Merkel cell carcinoma reveals ultraviolet-signature mutations and recurrent TP53 and RB1 inactivation.

Harms PW, Collie AM, Hovelson DH, Cani AK, Verhaegen ME, Patel RM, Fullen DR, Omata K, Dlugosz AA, Tomlins SA, Billings SD.

Mod Pathol. 2016 Mar;29(3):240-8. doi: 10.1038/modpathol.2015.154. Epub 2016 Jan 8.

50.

SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF NEW SULFONAMIDE ISOXAZOLO[5,4-b]PYRIDINE DERIVATIVES.

Poręba K, Pawlik K, Rembacz KP, Kurowska E, Matuszyk J, Długosz A.

Acta Pol Pharm. 2015 Jul-Aug;72(4):727-35.

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